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Volumn 53, Issue , 2012, Pages 403-407

Anticancer and radiosensitizing evaluation of some new pyranothiazole- Schiff bases bearing the biologically active sulfonamide moiety

(5) Ghorab, Mostafa M a Shaaban, Mohamed A b Refaat, Hanan M b Heiba, Helmy I c Ibrahim, Sara S c

a KING SAUD UNIVERSITY (Saudi Arabia)

b CAIRO UNIVERSITY (Egypt)

c NATIONAL CENTER FOR RADIATION RESEARCH AND TECHNOLOGY (Egypt)

Author keywords

Carbonic anhydrase inhibitors; Cytotoxicity; Pyranothiazole; Radiosensitizing activities; Sulfonamides

Indexed keywords

4 (4 OXO 4,5 DIHYDROTHIAZOL 2 YLAMINO)BENZENESULFONAMIDE; 5 (2 CHLOROBENZYLIDENEAMINO) 6 CYANO 7H 7 (4 METHOXYPHENYL) 2 (4 SULPHAMOYLPHENYLAMINO)PYRANO[2,3 D]THIAZOLE; 5 (3 BROMOBENZYLIDENEAMINO) 6 CYANO 7H 7 (4 METHOXYPHENYL) 2 (4 SULPHAMOYLPHENYLAMINO)PYRANO[2,3 D]THIAZOLE; 5 (4 CHLOROBENZYLIDENEAMINO) 6 CYANO 7H 7 (4 METHOXYPHENYL) 2 (4 SULPHAMOYLPHENYLAMINO)PYRANO[2,3 D]THIAZOLE; 5 (BENZYLIDENEAMINO) 6 CYANO 7H 7 (4 METHOXYPHENYL) 2 (4 SULPHAMOYLPHENYLAMINO)PYRANO[2,3 D]THIAZOLE; 5 (SUBSTITUTED BENZYLIDENEAMINO) 6 CYANO 7H 7 (4 METHOXYPHENYL) 2 (4 SULPHAMOYLPHENYLAMINO) PYRANO[2,3 D]THIAZOLE; 5 (SUBSTITUTED BENZYLIDENEAMINO) 6 CYANO 7H 7 (4 METHOXYPHENYL) 2 (4 SULPHAMOYLPHENYLAMINO)PYRANO[2,3 D]THIAZOLE; 5 [(BENZO [1,3 B] DIOXOL 5 YLMETHYLENE)AMINO] 6 CYANO 7H 7 (4 METHOXYPHENYL) 2 (4 SULPHAMOYLPHENYLAMINO)PYRANO[2,3 D]THIAZOLE; 6 CYANO 5 (2,4 DICHLOROBENZYLIDENEAMINO) 7H 7 (4 METHOXYPHENYL) 2 (4 SULPHAMOYLPHENYLAMINO)PYRANO[2,3 D]THIAZOLE; 6 CYANO 5 (4 FLUOROBENZYLIDENEAMINO) 7H 7 (4 METHOXYPHENYL) 2 (4 SULPHAMOYLPHENYLAMINO)PYRANO[2,3 D]THIAZOLE; 6 CYANO 5 (4 HYDROXYBENZYLIDENEAMINO) 7H 7 (4 METHOXYPHENYL) 2 (4 SULPHAMOYLPHENYLAMINO)PYRANO[2,3 D]THIAZOLE; 6 CYANO 5 [4 (DIMETHYLAMINO)BENZYLIDENEAMINO] 7H 7 (4 METHOXYPHENYL) 2 (4 SULPHAMOYLPHENYLAMINO)PYRANO[2,3 D]THIAZOLE; 6 CYANO 7H 7 (4 METHOXYPHENYL) 5 (3 PHENYLALLYLIDENE)AMINO 2 (4 SULPHAMOYLPHENYLAMINO)PYRANO[2,3 D]THIAZOLE; 6 CYANO 7H 7 (4 METHOXYPHENYL) 5 (4 NITROBENZYLIDENEAMINO) 2 (4 SULPHAMOYLPHENYLAMINO)PYRANO[2,3 D]THIAZOLE; ANTINEOPLASTIC AGENT; DOXORUBICIN; PYRANOTHIAZOLE SCHIFF BASE; RADIOSENSITIZING AGENT; SCHIFF BASE; SULFONAMIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CELL KILLING; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GAMMA RADIATION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; RADIOSENSITIVITY;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; DRUG DESIGN; GAMMA RAYS; HUMANS; INHIBITORY CONCENTRATION 50; RADIATION-SENSITIZING AGENTS; SCHIFF BASES; SULFONAMIDES; THIAZOLES;

EID: 84861608778 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2012.04.009 Document Type: Article

Times cited : (35)

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