메뉴 건너뛰기




Volumn 40, Issue 3, 2014, Pages 295-302

HMG-CoA reductase inhibitors (statins), inflammation, and endothelial progenitor cells-New mechanistic insights of atherosclerosis

Author keywords

Atherosclerosis; Endothelial stem cells; Inflammation

Indexed keywords

C REACTIVE PROTEIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ESTROGEN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ROSUVASTATIN; AUTACOID; BIOLOGICAL MARKER;

EID: 84902536233     PISSN: 09516433     EISSN: 18728081     Source Type: Journal    
DOI: 10.1002/biof.1157     Document Type: Review
Times cited : (33)

References (100)
  • 1
    • 33745571976 scopus 로고    scopus 로고
    • The immune response in atherosclerosis: a double-edged sword
    • Hansson, G. K. and Libby, P. (2006) The immune response in atherosclerosis: a double-edged sword. Nat. Rev. Immunol. 6, 508-519.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 508-519
    • Hansson, G.K.1    Libby, P.2
  • 2
    • 0037163149 scopus 로고    scopus 로고
    • Innate and adaptive immunity in the pathogenesis of atherosclerosis
    • Hansson, G. K., Libby, P., Schonbeck, U., and Yan, Z.Q. (2002) Innate and adaptive immunity in the pathogenesis of atherosclerosis. Circ. Res. 91, 281-291.
    • (2002) Circ. Res. , vol.91 , pp. 281-291
    • Hansson, G.K.1    Libby, P.2    Schonbeck, U.3    Yan, Z.Q.4
  • 3
    • 51649118633 scopus 로고    scopus 로고
    • P-selectin glycoprotein ligand-1 is highly expressed on Ly-6Chi monocytes and a major determinant for Ly-6Chi monocyte recruitment to sites of atherosclerosis in mice
    • An, G., Wang, H., Tang, R., Yago T., McDaniel J. M., et al. (2008) P-selectin glycoprotein ligand-1 is highly expressed on Ly-6Chi monocytes and a major determinant for Ly-6Chi monocyte recruitment to sites of atherosclerosis in mice. Circulation 117, 3227-3337.
    • (2008) Circulation , vol.117 , pp. 3227-3337
    • An, G.1    Wang, H.2    Tang, R.3    Yago, T.4    McDaniel, J.M.5
  • 4
    • 34250014988 scopus 로고    scopus 로고
    • Mast cells promote atherosclerosis by releasing proinflammatory cytokines
    • Sun, J., Sukhova, G. K., Wolters, P. J., Yang M., Kitamoto S. (2007) Mast cells promote atherosclerosis by releasing proinflammatory cytokines. Nat. Med. 13, 719-724.
    • (2007) Nat. Med. , vol.13 , pp. 719-724
    • Sun, J.1    Sukhova, G.K.2    Wolters, P.J.3    Yang, M.4    Kitamoto, S.5
  • 5
    • 34248531976 scopus 로고    scopus 로고
    • Perivascular mast cells promote atherogenesis and induce plaque destabilization in apolipoprotein E deficient mice
    • Bot, I., de Jager, S. C., Zernecke, A., Lindstedt K. A., van Berkel T. J., et al. (2007) Perivascular mast cells promote atherogenesis and induce plaque destabilization in apolipoprotein E deficient mice. Circulation 115, 2516-2525.
    • (2007) Circulation , vol.115 , pp. 2516-2525
    • Bot, I.1    de Jager, S.C.2    Zernecke, A.3    Lindstedt, K.A.4    van Berkel, T.J.5
  • 6
    • 54049152760 scopus 로고    scopus 로고
    • Effects of the direct lipoprotein associated phospholipase A2 inhibitor darapladib on human coronary atherosclerotic plaque
    • Serruys, R. W., Garcia-Garcia, H. M., Buszman, P., Erne P., Verheye S., et al. (2008) Effects of the direct lipoprotein associated phospholipase A2 inhibitor darapladib on human coronary atherosclerotic plaque. Circulation 118, 1172-1182.
    • (2008) Circulation , vol.118 , pp. 1172-1182
    • Serruys, R.W.1    Garcia-Garcia, H.M.2    Buszman, P.3    Erne, P.4    Verheye, S.5
  • 7
    • 33845358396 scopus 로고    scopus 로고
    • Intertwining of thrombosis and inflammation in atherosclerosis
    • Croce, K. and Libby, P. (2007) Intertwining of thrombosis and inflammation in atherosclerosis. Curr. Opin. Hematol., 14, 55-61.
    • (2007) Curr. Opin. Hematol. , vol.14 , pp. 55-61
    • Croce, K.1    Libby, P.2
  • 8
    • 70450189795 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis. From pathophysiology to practice
    • Libby, P., Ridker, P. M., and Hansson, G. K. (2009) Inflammation in atherosclerosis. From pathophysiology to practice. J. Am. Coll. Cardiol. 54, 2129-2138.
    • (2009) J. Am. Coll. Cardiol. , vol.54 , pp. 2129-2138
    • Libby, P.1    Ridker, P.M.2    Hansson, G.K.3
  • 9
    • 0042926424 scopus 로고    scopus 로고
    • The role of interleukin-4 and interleukin-12 in the progression of atherosclerosis in apolipoprotein E deficient mice
    • Davenport, P. and Tipping, P. G. (2003). The role of interleukin-4 and interleukin-12 in the progression of atherosclerosis in apolipoprotein E deficient mice. Am. J. Pathol. 163, 1117-1125.
    • (2003) Am. J. Pathol. , vol.163 , pp. 1117-1125
    • Davenport, P.1    Tipping, P.G.2
  • 10
    • 4043152981 scopus 로고    scopus 로고
    • IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis
    • Binder, C. J., Hartvigsen, K., Chang, M. K., Miller M., Broide D., et al. (2004) IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis. J. Clin. Invest. 114, 427-437.
    • (2004) J. Clin. Invest. , vol.114 , pp. 427-437
    • Binder, C.J.1    Hartvigsen, K.2    Chang, M.K.3    Miller, M.4    Broide, D.5
  • 11
    • 21044439562 scopus 로고    scopus 로고
    • Atheroprotective immunization with MDA-modified apo B-100 peptide sequences is associated with activation of the TH2 specific antibody expression
    • Fredrikson, G. N., Andersson, L., Soderberg, I., Dimayuga P., Chyu K. Y., et al. (2005) Atheroprotective immunization with MDA-modified apo B-100 peptide sequences is associated with activation of the TH2 specific antibody expression. Autoimmunity 38, 171-179.
    • (2005) Autoimmunity , vol.38 , pp. 171-179
    • Fredrikson, G.N.1    Andersson, L.2    Soderberg, I.3    Dimayuga, P.4    Chyu, K.Y.5
  • 12
    • 33847688373 scopus 로고    scopus 로고
    • Interruption of the Tnfrsf4/Tnfsf4 (OX40/OX40L) pathway attenuates atherogenesis in low-density lipoprotein receptor-deficient mice
    • Van Wanrooij, E. J., van Puijvelde, G. H., de Vos, P., Yagita, H., van Berkel, T. J., et al. (2007) Interruption of the Tnfrsf4/Tnfsf4 (OX40/OX40L) pathway attenuates atherogenesis in low-density lipoprotein receptor-deficient mice. Arterioscler. Thromb. Vasc. Biol. 27, 204-210.
    • (2007) Arterioscler. Thromb. Vasc. Biol. , vol.27 , pp. 204-210
    • Van Wanrooij, E.J.1    van Puijvelde, G.H.2    de Vos, P.3    Yagita, H.4    van Berkel, T.J.5
  • 13
    • 0346726036 scopus 로고    scopus 로고
    • Disruption of TGF-beta signaling in T cells accelerates atherosclerosis
    • Robertson, A. K., Rudling, M., Zhou, X., Gorerlik, L., Flavell, R. A., et al. (2003) Disruption of TGF-beta signaling in T cells accelerates atherosclerosis. J. Clin. Invest. 112, 1342-1350.
    • (2003) J. Clin. Invest. , vol.112 , pp. 1342-1350
    • Robertson, A.K.1    Rudling, M.2    Zhou, X.3    Gorerlik, L.4    Flavell, R.A.5
  • 14
    • 32244445416 scopus 로고    scopus 로고
    • Natural regulatory T cells control the development of atherosclerosis in mice
    • Ait-Oufella, H., Salomon, B. L., Potteaux, S., Robertson A. K., Gourdy P. (2006) Natural regulatory T cells control the development of atherosclerosis in mice. Nat. Med. 12, 178-180.
    • (2006) Nat. Med. , vol.12 , pp. 178-180
    • Ait-Oufella, H.1    Salomon, B.L.2    Potteaux, S.3    Robertson, A.K.4    Gourdy, P.5
  • 15
    • 0033749397 scopus 로고    scopus 로고
    • Linking immune-mediated arterial inflammation and cholesterol-induced atherosclerosis in a transgenic mouse model
    • Ludewig, B., Freigang, S., Jaggi, M., Kurrer M. O., Pei Y. C., et al. (2009) Linking immune-mediated arterial inflammation and cholesterol-induced atherosclerosis in a transgenic mouse model. Proc. Natl. Acad. Sci. USA 97, 12752-12757.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 12752-12757
    • Ludewig, B.1    Freigang, S.2    Jaggi, M.3    Kurrer, M.O.4    Pei, Y.C.5
  • 16
    • 34248641015 scopus 로고    scopus 로고
    • C reactive protein and the prediction of cardiovascular events among those at intermediate risk: moving an inflammatory hypothesis toward consensus
    • Ridker, P. M. (2007) C reactive protein and the prediction of cardiovascular events among those at intermediate risk: moving an inflammatory hypothesis toward consensus. J. Am. Coll. Cardiol. 49, 2129-2138.
    • (2007) J. Am. Coll. Cardiol. , vol.49 , pp. 2129-2138
    • Ridker, P.M.1
  • 17
    • 18944371407 scopus 로고    scopus 로고
    • Relative efficacy of atrovastatin 80 mg and pravastatin 40 mg in achieving the dual goals of low density lipoprotein cholesterol<70 mg/dl and C reactive protein<2 mg/l: an analysis of the PROVE-IT TIMI 22 trial
    • Ridker, P. M., Morrow, D. A., Rose, L. M., Rifai, N., Cannon, C. P., et al. (2005) Relative efficacy of atrovastatin 80 mg and pravastatin 40 mg in achieving the dual goals of low density lipoprotein cholesterol<70 mg/dl and C reactive protein<2 mg/l: an analysis of the PROVE-IT TIMI 22 trial. J. Am. Coll. Cardiol. 45, 1644-1648.
    • (2005) J. Am. Coll. Cardiol. , vol.45 , pp. 1644-1648
    • Ridker, P.M.1    Morrow, D.A.2    Rose, L.M.3    Rifai, N.4    Cannon, C.P.5
  • 18
    • 33748064338 scopus 로고    scopus 로고
    • Clinical relevance of C reactive protein during follow-up of patients with acute coronary syndromes in the Aggrastat-to-Zocor trial
    • Morrow, D. A., de Lemos, J. A., Sabatine, M. S., Wiviott S. D., Blazing M. A. (2006) Clinical relevance of C reactive protein during follow-up of patients with acute coronary syndromes in the Aggrastat-to-Zocor trial. Circulation 114, 281-288.
    • (2006) Circulation , vol.114 , pp. 281-288
    • Morrow, D.A.1    de Lemos, J.A.2    Sabatine, M.S.3    Wiviott, S.D.4    Blazing, M.A.5
  • 19
    • 0035963529 scopus 로고    scopus 로고
    • Measurement of C reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events
    • Ridker, P. M., Rifai, N., Clearfield, M., Downs J. R., Weis S. E. (2001) Measurement of C reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events. N. Engl. J. Med. 344, 1959-1965.
    • (2001) N. Engl. J. Med. , vol.344 , pp. 1959-1965
    • Ridker, P.M.1    Rifai, N.2    Clearfield, M.3    Downs, J.R.4    Weis, S.E.5
  • 20
    • 56749106312 scopus 로고    scopus 로고
    • Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein
    • Ridker, P. M., Danielson, E., Fonseca, F. A. H., Genest J., Gotto A. M. Jr. (2008) Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N. Engl. J. Med. 359, 2195-2207.
    • (2008) N. Engl. J. Med. , vol.359 , pp. 2195-2207
    • Ridker, P.M.1    Danielson, E.2    Fonseca, F.A.H.3    Genest, J.4    Gotto, A.M.5
  • 21
    • 54049108847 scopus 로고    scopus 로고
    • Inhibition of lipoprotein-associated phospholipase activity by darapladib: shifting gears in cardiovascular drug development: are anti-inflammatory drugs the next frontier?
    • Boekholdt, S. M., de Winter, R. J., Kastelein, J. J. (2008) Inhibition of lipoprotein-associated phospholipase activity by darapladib: shifting gears in cardiovascular drug development: are anti-inflammatory drugs the next frontier? Circulation 118, 1120-1122.
    • (2008) Circulation , vol.118 , pp. 1120-1122
    • Boekholdt, S.M.1    de Winter, R.J.2    Kastelein, J.J.3
  • 22
    • 42149158984 scopus 로고    scopus 로고
    • Introduction: atherosclerosis as inflammation: a controversial concept becomes accepted
    • Hansson, G. K. and Nilsson, J. (2008) Introduction: atherosclerosis as inflammation: a controversial concept becomes accepted. J. Int. Med. 263, 462-463.
    • (2008) J. Int. Med. , vol.263 , pp. 462-463
    • Hansson, G.K.1    Nilsson, J.2
  • 23
    • 84877137963 scopus 로고    scopus 로고
    • Lipid lowering and HDL raising gene transfer increase endothelial progenitor cells, enhance myocardial vascularity, and improve diastolic function
    • Gordts, S. C., Van Craeyveld, E., Muthuramu, I., Singh, N., Jacobs, F., et al. (2012) Lipid lowering and HDL raising gene transfer increase endothelial progenitor cells, enhance myocardial vascularity, and improve diastolic function. PLoS One 7, e46849.
    • (2012) PLoS One , vol.7
    • Gordts, S.C.1    Van Craeyveld, E.2    Muthuramu, I.3    Singh, N.4    Jacobs, F.5
  • 24
    • 84864887891 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor gene transfer in hypercholesterolemic mice improves cardiac function after myocardial infarction
    • Van Craeyveld, E., Jacobs, F., Gordts, S. C., De Geest, B. (2012) Low-density lipoprotein receptor gene transfer in hypercholesterolemic mice improves cardiac function after myocardial infarction. Gene Ther. 19, 860-871.
    • (2012) Gene Ther. , vol.19 , pp. 860-871
    • Van Craeyveld, E.1    Jacobs, F.2    Gordts, S.C.3    De Geest, B.4
  • 25
    • 0035943091 scopus 로고    scopus 로고
    • Cervistatin, a hydroxymethylglutaryl coenzyme A reductase inhibitor, improves endothelial function in elderly diabetic patients within 3 days
    • Tsunekawa, T., Hayashi, T., Kano, H., Sumi D., Matsui-Hirai H. (2001) Cervistatin, a hydroxymethylglutaryl coenzyme A reductase inhibitor, improves endothelial function in elderly diabetic patients within 3 days. Circulation 104, 376-379.
    • (2001) Circulation , vol.104 , pp. 376-379
    • Tsunekawa, T.1    Hayashi, T.2    Kano, H.3    Sumi, D.4    Matsui-Hirai, H.5
  • 26
    • 33846008765 scopus 로고    scopus 로고
    • Endothelial dysfunction, oxidative stress and inflammation in atherosclerosis: beneficial effects of statins
    • Laheta, V., Goicoechea, M., Garcia de Vinuesa, S., de Vinuesa S. G., Praga M. (2007) Endothelial dysfunction, oxidative stress and inflammation in atherosclerosis: beneficial effects of statins. Curr. Med. Chem. 14, 243-248.
    • (2007) Curr. Med. Chem. , vol.14 , pp. 243-248
    • Laheta, V.1    Goicoechea, M.2    Garcia de Vinuesa, S.3    de Vinuesa, S.G.4    Praga, M.5
  • 27
    • 0037233913 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors regulate inflammatory transcription factors in human endothelial and vascular smooth muscle cells
    • Dichtl, W., Dulak, J., Frick, M., Alber H. F., Schwarzacher S. P., et al. (2003) HMG-CoA reductase inhibitors regulate inflammatory transcription factors in human endothelial and vascular smooth muscle cells. Arterioscler. Thromb. Vasc. Biol. 23, 58-63.
    • (2003) Arterioscler. Thromb. Vasc. Biol. , vol.23 , pp. 58-63
    • Dichtl, W.1    Dulak, J.2    Frick, M.3    Alber, H.F.4    Schwarzacher, S.P.5
  • 28
    • 84862502750 scopus 로고    scopus 로고
    • Lipid-related markers and cardiovascular disease prediction
    • Di Angelantonio, E., Gao P., Pennells L., Kaptoge S., Caslake M., et al. (2012) Lipid-related markers and cardiovascular disease prediction. JAMA 307:2499-2506.
    • (2012) JAMA , vol.307 , pp. 2499-2506
    • Di Angelantonio, E.1    Gao, P.2    Pennells, L.3    Kaptoge, S.4    Caslake, M.5
  • 29
    • 77955585234 scopus 로고    scopus 로고
    • Study design and rationale for the clinical outcomes of the STABILITY Trial (STabilization of Atherosclerotic plaque By Initiation of darapLadIb TherapY) comparing darapladib versus placebo in patients with coronary heart disease
    • White, H., Held, C., Stewart, R., Watson D., Harrington R., et al. (2010) Study design and rationale for the clinical outcomes of the STABILITY Trial (STabilization of Atherosclerotic plaque By Initiation of darapLadIb TherapY) comparing darapladib versus placebo in patients with coronary heart disease. Am. Heart J. 160, 655-661.
    • (2010) Am. Heart J. , vol.160 , pp. 655-661
    • White, H.1    Held, C.2    Stewart, R.3    Watson, D.4    Harrington, R.5
  • 30
    • 80053644777 scopus 로고    scopus 로고
    • Interleukin-1β inhibition and the prevention of recurrent cardiovascular events: rationale and design of the Canakinumab Anti-inflammatory thrombosis outcomes study (CANTOS)
    • Ridker, P. M., Thuren, T., Zalewski, A., and Libby, P. (2011) Interleukin-1β inhibition and the prevention of recurrent cardiovascular events: rationale and design of the Canakinumab Anti-inflammatory thrombosis outcomes study (CANTOS). Am. Heart J. 162, 597-605.
    • (2011) Am. Heart J. , vol.162 , pp. 597-605
    • Ridker, P.M.1    Thuren, T.2    Zalewski, A.3    Libby, P.4
  • 31
    • 0344013648 scopus 로고    scopus 로고
    • Inhibition of hydroxymethylglutaryl-coenzyme A reductase reduces Th1 development and promotes Th2 development
    • Hakamada-Taguchi, R., Uehara, Y., Kuribayashi, K., Numabe A., Saito K. (2003) Inhibition of hydroxymethylglutaryl-coenzyme A reductase reduces Th1 development and promotes Th2 development. Circ. Res. 93, 948-956.
    • (2003) Circ. Res. , vol.93 , pp. 948-956
    • Hakamada-Taguchi, R.1    Uehara, Y.2    Kuribayashi, K.3    Numabe, A.4    Saito, K.5
  • 32
    • 0032584177 scopus 로고    scopus 로고
    • Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors
    • Laufs, U., La Fata, V., Plutzky, J., Liao, K. L. (1998) Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors. Circulation 97, 1129-1135.
    • (1998) Circulation , vol.97 , pp. 1129-1135
    • Laufs, U.1    La Fata, V.2    Plutzky, J.3    Liao, K.L.4
  • 33
    • 37049021538 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibition improves anti-aging klotho protein expression and arteriosclerosis in rats with chronic inhibition of nitric oxide synthesis
    • Kuwahara, N., Sasaki, S., Kobara, M., Nakata T., Tatsumi T., (2008) HMG-CoA reductase inhibition improves anti-aging klotho protein expression and arteriosclerosis in rats with chronic inhibition of nitric oxide synthesis. Int. J. Cardiol. 123, 84-90.
    • (2008) Int. J. Cardiol. , vol.123 , pp. 84-90
    • Kuwahara, N.1    Sasaki, S.2    Kobara, M.3    Nakata, T.4    Tatsumi, T.5
  • 34
    • 0035826856 scopus 로고    scopus 로고
    • Simvastatin depresses blood clotting by inhibiting activation of prothrombin, factor V, and factor XIII and by enhancing factor Va inactivation
    • Undas, A., Brummel, K. E., Musial, J., Mann, K. G., Szczeklik, A. (2001) Simvastatin depresses blood clotting by inhibiting activation of prothrombin, factor V, and factor XIII and by enhancing factor Va inactivation. Circulation 103, 2248-2253.
    • (2001) Circulation , vol.103 , pp. 2248-2253
    • Undas, A.1    Brummel, K.E.2    Musial, J.3    Mann, K.G.4    Szczeklik, A.5
  • 35
    • 0036305114 scopus 로고    scopus 로고
    • Atorvastatin and thrombogenicity of the carotid atherosclerotic plaque: the ATROCAP study
    • Cortellaro, M., Cofranceso, E., Arbustini, E., Rossi F., Negri A., et al. (2002) Atorvastatin and thrombogenicity of the carotid atherosclerotic plaque: the ATROCAP study. Thromb. Haemost. 88:41-47.
    • (2002) Thromb. Haemost. , vol.88 , pp. 41-47
    • Cortellaro, M.1    Cofranceso, E.2    Arbustini, E.3    Rossi, F.4    Negri, A.5
  • 36
    • 0034926855 scopus 로고    scopus 로고
    • Endothelial function and coronary artery disease
    • Kinlay, S., Libby, P., and Ganz, P. (2001) Endothelial function and coronary artery disease. Curr. Opin. Lipidol. 12, 383-389.
    • (2001) Curr. Opin. Lipidol. , vol.12 , pp. 383-389
    • Kinlay, S.1    Libby, P.2    Ganz, P.3
  • 37
    • 0031265794 scopus 로고    scopus 로고
    • Biology of the endothelium
    • II-3-II-10
    • Luscher, T. F. and Barton, M. (1997) Biology of the endothelium. Clin. Cardiol. 20(suppl II):II-3-II-10.
    • (1997) Clin. Cardiol. , vol.20 , Issue.SUPPL. II
    • Luscher, T.F.1    Barton, M.2
  • 38
    • 0032548092 scopus 로고    scopus 로고
    • Factors involved in the maintenance of endothelial function
    • Drexler, H. (1998) Factors involved in the maintenance of endothelial function. Am. J. Cardiol. 82:3S-4S.
    • (1998) Am. J. Cardiol. , vol.82
    • Drexler, H.1
  • 39
    • 0037142095 scopus 로고    scopus 로고
    • Hypertension, angiotensin II, and oxidative stress
    • Sowers, J. R. (2002) Hypertension, angiotensin II, and oxidative stress. N. Engl. J. Med. 346, 1999-2001.
    • (2002) N. Engl. J. Med. , vol.346 , pp. 1999-2001
    • Sowers, J.R.1
  • 40
    • 0032584177 scopus 로고    scopus 로고
    • Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors
    • Laufs, U., La Fata, V., Plutzky, J., Liao J. K. (1998) Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors. Circulation 97, 1129-1135.
    • (1998) Circulation , vol.97 , pp. 1129-1135
    • Laufs, U.1    La Fata, V.2    Plutzky, J.3    Liao, J.K.4
  • 41
    • 0034730812 scopus 로고    scopus 로고
    • Targeting Rho in cardiovascular disease
    • Laufs, U. and Liao, J. K. (2000) Targeting Rho in cardiovascular disease. Circ. Res. 87, 526-528.
    • (2000) Circ. Res. , vol.87 , pp. 526-528
    • Laufs, U.1    Liao, J.K.2
  • 42
    • 0033782877 scopus 로고    scopus 로고
    • Fluvastatin reduces soluble P-selectin and ICAM-1 levels in hypercholesterolemic patients: role of nitric oxide
    • Romano, M., Mezzetti, A., Marulli, C., Ciabattoni G., Febo F. (2000) Fluvastatin reduces soluble P-selectin and ICAM-1 levels in hypercholesterolemic patients: role of nitric oxide. J. Investig. Med. 48, 183-189.
    • (2000) J. Investig. Med. , vol.48 , pp. 183-189
    • Romano, M.1    Mezzetti, A.2    Marulli, C.3    Ciabattoni, G.4    Febo, F.5
  • 43
    • 0027445164 scopus 로고
    • The role of endothelium in cardiovascular homeostasis and diseases
    • Rubanayi, G. M. (1993) The role of endothelium in cardiovascular homeostasis and diseases. J. Cardiovasc. Oharmacol. 22(Suppl4):S1-14.
    • (1993) J. Cardiovasc. Oharmacol. , vol.22 , Issue.SUPPL.4
    • Rubanayi, G.M.1
  • 44
    • 0026478022 scopus 로고
    • Non invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis
    • Celermajer, D. S., Sorensen, K. E., Gooch, V. M., Spiegelhalter D. J., Miller O. I. (1992) Non invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet 340, 1111-1115.
    • (1992) Lancet , vol.340 , pp. 1111-1115
    • Celermajer, D.S.1    Sorensen, K.E.2    Gooch, V.M.3    Spiegelhalter, D.J.4    Miller, O.I.5
  • 45
    • 0028784709 scopus 로고
    • Close relation of endothelial function in the human coronary and peripheral circulations
    • Anderson, T. J., Uehata, A., Gerhard, M. D., Meredith I. T., Knab S. et al. (1995) Close relation of endothelial function in the human coronary and peripheral circulations. J. Am. Coll. Cardiol. 26, 1235-1241.
    • (1995) J. Am. Coll. Cardiol. , vol.26 , pp. 1235-1241
    • Anderson, T.J.1    Uehata, A.2    Gerhard, M.D.3    Meredith, I.T.4    Knab, S.5
  • 46
    • 0031786766 scopus 로고    scopus 로고
    • Cholesterol, cholesterol lowering, and endothelial function
    • Vogel, R. A., Corretti, M. C., and Gellman, J. (1998) Cholesterol, cholesterol lowering, and endothelial function. Prog. Cardiovascul. Dis. 41, 117-136.
    • (1998) Prog. Cardiovascul. Dis. , vol.41 , pp. 117-136
    • Vogel, R.A.1    Corretti, M.C.2    Gellman, J.3
  • 47
    • 0035022781 scopus 로고    scopus 로고
    • Endothelium-dependent and independent vasodilation studies at normoglycemia in type 1 diabetes mellitus with and without microalbuminuria
    • Dogra, G., Rich, L., Stanton, K., and Watts, G. F. (2001) Endothelium-dependent and independent vasodilation studies at normoglycemia in type 1 diabetes mellitus with and without microalbuminuria. Diabetologia 44, 593-601.
    • (2001) Diabetologia , vol.44 , pp. 593-601
    • Dogra, G.1    Rich, L.2    Stanton, K.3    Watts, G.F.4
  • 48
    • 0034047179 scopus 로고    scopus 로고
    • Late prognostic value of flow mediated dilation in the brachial artery of patients with chest pain
    • Neunteufl, T., Neher, S., Katzenschlager, R., Wölfl G., Kostner K., et al. (2000) Late prognostic value of flow mediated dilation in the brachial artery of patients with chest pain. Am. J. Cardiol. 86, 207-210.
    • (2000) Am. J. Cardiol. , vol.86 , pp. 207-210
    • Neunteufl, T.1    Neher, S.2    Katzenschlager, R.3    Wölfl, G.4    Kostner, K.5
  • 49
    • 0035991539 scopus 로고    scopus 로고
    • Statin therapy improves brachial artery endothelial function in nephritic syndrome
    • Dogra, G. K., Watts, G. F., Herrmann, S., Thomas, M. A. B., and Irish, A. B. (2002) Statin therapy improves brachial artery endothelial function in nephritic syndrome. Kid. Int. 62, 550-557.
    • (2002) Kid. Int. , vol.62 , pp. 550-557
    • Dogra, G.K.1    Watts, G.F.2    Herrmann, S.3    Thomas, M.A.B.4    Irish, A.B.5
  • 50
    • 17844408136 scopus 로고    scopus 로고
    • Lipid independent effects of statins on endothelial function and bioavailability of nitric oxide in hypercholesterolemic patients
    • John, S., Schneider, M. P., Delles, C., Jacobi, J., and Schmieder, R. E. (2005) Lipid independent effects of statins on endothelial function and bioavailability of nitric oxide in hypercholesterolemic patients. Am. Heart J. 149: 473-475.
    • (2005) Am. Heart J. , vol.149 , pp. 473-475
    • John, S.1    Schneider, M.P.2    Delles, C.3    Jacobi, J.4    Schmieder, R.E.5
  • 51
    • 2942733214 scopus 로고    scopus 로고
    • Role of endothelial dysfunction in atherosclerosis
    • III-27-III-32
    • Davignon, J. and Ganz, P. (2004) Role of endothelial dysfunction in atherosclerosis. Circulation 109(suppl III): III-27-III-32.
    • (2004) Circulation , vol.109 , Issue.SUPPL. III
    • Davignon, J.1    Ganz, P.2
  • 52
    • 24944587279 scopus 로고    scopus 로고
    • The effect of statin therapy on endothelial function in type 2 diabetes without manifest cardiovascular disease
    • Beishuizen, E. D., Tamsma, J. T., Jukema, J. W., van de Ree M. .A, van der Vijver J. C., et al. (2005) The effect of statin therapy on endothelial function in type 2 diabetes without manifest cardiovascular disease. Diabetes Care 28:1668-1674.
    • (2005) Diabetes Care , vol.28 , pp. 1668-1674
    • Beishuizen, E.D.1    Tamsma, J.T.2    Jukema, J.W.3    van de Ree, M.A.4    van der Vijver, J.C.5
  • 53
    • 0033782877 scopus 로고    scopus 로고
    • Fluvastatin reduces soluble P-selectin and ICAM-1 levels in hypercholesterolemic patients: role of nitric oxide
    • Romano, M., Mezzetti, A., Marulli, C., Ciabattoni G., Febo F. (2000) Fluvastatin reduces soluble P-selectin and ICAM-1 levels in hypercholesterolemic patients: role of nitric oxide. J. Incest. Med. 48, 183-189.
    • (2000) J. Incest. Med. , vol.48 , pp. 183-189
    • Romano, M.1    Mezzetti, A.2    Marulli, C.3    Ciabattoni, G.4    Febo, F.5
  • 54
    • 0035830412 scopus 로고    scopus 로고
    • Hydroxy-methylglutaryl-coenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance
    • Feron, O., Dessy, C., Desager, J. P., Balligand J. L. (2001) Hydroxy-methylglutaryl-coenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance. Circulation 103, 113-118.
    • (2001) Circulation , vol.103 , pp. 113-118
    • Feron, O.1    Dessy, C.2    Desager, J.P.3    Balligand, J.L.4
  • 55
    • 0035569562 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species
    • Müller K., Ahlbory K. () .
    • Wassmann, S., Laufs, U., Baumer, A. T., Müller K., Ahlbory K. (2001) HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species. Hypertension 37, 1450-1457.
    • (2001) Hypertension , vol.37 , pp. 1450-1457
    • Wassmann, S.1    Laufs, U.2    Baumer, A.T.3
  • 56
    • 2942720515 scopus 로고    scopus 로고
    • Beneficial cardiovascular pleiotropic effects of statins
    • III-39-III-43
    • Davignon, J. (2004) Beneficial cardiovascular pleiotropic effects of statins. Circulation 109: III-39-III-43.
    • (2004) Circulation , vol.109
    • Davignon, J.1
  • 57
    • 0033826581 scopus 로고    scopus 로고
    • The HMG-CoA redcuctase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals
    • Kureishi, Y., Luo, Z. Y., Dhiojima, I., Bialik A., Fulton D. (2000) The HMG-CoA redcuctase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals. Nat. Med. 6, 1004-1010.
    • (2000) Nat. Med. , vol.6 , pp. 1004-1010
    • Kureishi, Y.1    Luo, Z.Y.2    Dhiojima, I.3    Bialik, A.4    Fulton, D.5
  • 58
    • 0037031094 scopus 로고    scopus 로고
    • MRC/BHF heart protection study of antioxidant vitamin supplementation in 20536 high risk individuals: a randomized placebo-controlled trial
    • Heart Protection Study Collaborative Group. () .
    • Heart Protection Study Collaborative Group. (2002) MRC/BHF heart protection study of antioxidant vitamin supplementation in 20536 high risk individuals: a randomized placebo-controlled trial. Lancet 360, 23-33.
    • (2002) Lancet , vol.360 , pp. 23-33
  • 59
    • 0035176943 scopus 로고    scopus 로고
    • The oxidative modification hypothesis of atherosclerosis: does it hold for humans?
    • Witztum, J. L. and Steinberg, D. (2001) The oxidative modification hypothesis of atherosclerosis: does it hold for humans? Trends Cardiovasc. Med. 11: 93-102.
    • (2001) Trends Cardiovasc. Med. , vol.11 , pp. 93-102
    • Witztum, J.L.1    Steinberg, D.2
  • 60
    • 0033559426 scopus 로고    scopus 로고
    • Protective effect of fluvastatin sodium (XU-62-320), a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor on oxidative modification of human low density lipoprotein in vitro
    • Suzumura, K., Yasuhara, M., Tanaka, K., Suzuki T. (1999) Protective effect of fluvastatin sodium (XU-62-320), a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor on oxidative modification of human low density lipoprotein in vitro. Biochem. Pharmacol. 57, 697-703.
    • (1999) Biochem. Pharmacol. , vol.57 , pp. 697-703
    • Suzumura, K.1    Yasuhara, M.2    Tanaka, K.3    Suzuki, T.4
  • 61
    • 0031985499 scopus 로고    scopus 로고
    • Interactions of platelets, macrophages, and lipoproteins in hypercholesterolemia: antiatherogenic effects of HMG-CoA reductase inhibitor therapy
    • Aviram, M., Hussein, O., Rosenblat, M., Schlezinger S., Hayek T. (1998) Interactions of platelets, macrophages, and lipoproteins in hypercholesterolemia: antiatherogenic effects of HMG-CoA reductase inhibitor therapy. J. Cardiovasc. Pharmacol. 31, 39-45.
    • (1998) J. Cardiovasc. Pharmacol. , vol.31 , pp. 39-45
    • Aviram, M.1    Hussein, O.2    Rosenblat, M.3    Schlezinger, S.4    Hayek, T.5
  • 62
    • 0027492038 scopus 로고
    • Simvastatin inhibits the oxidation of low density lipoproteins by activated human monocyte-derived macrophages
    • Giroux, L. M., Davignon, J., and Naruszewicz, M. (1993) Simvastatin inhibits the oxidation of low density lipoproteins by activated human monocyte-derived macrophages. Biochim. Biophys. Acta. 1165, 335-338.
    • (1993) Biochim. Biophys. Acta. , vol.1165 , pp. 335-338
    • Giroux, L.M.1    Davignon, J.2    Naruszewicz, M.3
  • 63
    • 0041769306 scopus 로고    scopus 로고
    • Effect of simvastatin treatment on the electronegative low density lipoprotein present in patients with heterozygous familial hypercholesterolemia
    • Sanchez-Quesada, J. L., Otal-Entraigas, C., Franco, M., Jorba O., González-Sastre F. (1999) Effect of simvastatin treatment on the electronegative low density lipoprotein present in patients with heterozygous familial hypercholesterolemia. Am. J. Cardiol. 84, 655-659.
    • (1999) Am. J. Cardiol. , vol.84 , pp. 655-659
    • Sanchez-Quesada, J.L.1    Otal-Entraigas, C.2    Franco, M.3    Jorba, O.4    González-Sastre, F.5
  • 64
    • 0032169240 scopus 로고    scopus 로고
    • for the cholesterol and recurrent events (CARE) investigators. Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in patients with average cholesterol levels
    • Ridker, P. M., Rifai, N., Pfeffer, M. A., Sacks F. M., Moye L. A., et al. (1998) for the cholesterol and recurrent events (CARE) investigators. Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in patients with average cholesterol levels. Circulation 98, 839-844.
    • (1998) Circulation , vol.98 , pp. 839-844
    • Ridker, P.M.1    Rifai, N.2    Pfeffer, M.A.3    Sacks, F.M.4    Moye, L.A.5
  • 65
    • 0034687438 scopus 로고    scopus 로고
    • Markers of myocardial damage and inflammation in relation to long term mortality in unstable coronary artery disease
    • Lindahl, B., Toss, H., Siegbahn, A., Venge P., Wallentin L. (2000) Markers of myocardial damage and inflammation in relation to long term mortality in unstable coronary artery disease. N. Engl. J. Med. 343, 1139-1147.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 1139-1147
    • Lindahl, B.1    Toss, H.2    Siegbahn, A.3    Venge, P.4    Wallentin, L.5
  • 66
    • 0033587667 scopus 로고    scopus 로고
    • Long term effects of pravastatin on plasma concentration of C reactive protein
    • for the Cholesterol and Recurrent Events (CARE) Investigators. () .
    • Ridker, P. M., Rifai, N., Pfeffer, M. A., Sacks F., Braunwald E., for the Cholesterol and Recurrent Events (CARE) Investigators. (1999) Long term effects of pravastatin on plasma concentration of C reactive protein. Circulation 100, 230-235.
    • (1999) Circulation , vol.100 , pp. 230-235
    • Ridker, P.M.1    Rifai, N.2    Pfeffer, M.A.3    Sacks, F.4    Braunwald, E.5
  • 67
    • 0035806626 scopus 로고    scopus 로고
    • Effect of statin therapy on C reactive protein levels-the prasavtatin inflammation/CRP evaluation (PRINCE): a randomized trial and cohort study
    • Ridker P. M., PRINCE Investigators. () .
    • Albert, M. A., Danielson, E., Rifai, N., Ridker P. M., PRINCE Investigators. (2001) Effect of statin therapy on C reactive protein levels-the prasavtatin inflammation/CRP evaluation (PRINCE): a randomized trial and cohort study. JAMA 286, 64-70.
    • (2001) JAMA , vol.286 , pp. 64-70
    • Albert, M.A.1    Danielson, E.2    Rifai, N.3
  • 68
    • 0036890370 scopus 로고    scopus 로고
    • Differential hs-CRP reduction in patients with familial hypercholesterolemia treated with aggressive or conventional statin therapy
    • Van Wissen, S., Trip, M. D., Snilde, T. J., de Graaf J., Stalenhoef A. F., Kastelein J. J. (2002) Differential hs-CRP reduction in patients with familial hypercholesterolemia treated with aggressive or conventional statin therapy. Atherosclerosis 165, 361-366.
    • (2002) Atherosclerosis , vol.165 , pp. 361-366
    • Van Wissen, S.1    Trip, M.D.2    Snilde, T.J.3    de Graaf, J.4    Stalenhoef, A.F.5    Kastelein, J.J.6
  • 69
    • 0037126043 scopus 로고    scopus 로고
    • Simvastatin lowers C reactive protein within 14 days: an effect independent of low density lipoprotein cholesterol reduction
    • Plenge, J. K., Hernandez, T. L., Weil, K. M., Poirier P., Grunwald G. K., et al. (2002) Simvastatin lowers C reactive protein within 14 days: an effect independent of low density lipoprotein cholesterol reduction. Circulation 106, 1447-1452.
    • (2002) Circulation , vol.106 , pp. 1447-1452
    • Plenge, J.K.1    Hernandez, T.L.2    Weil, K.M.3    Poirier, P.4    Grunwald, G.K.5
  • 70
    • 0036239382 scopus 로고    scopus 로고
    • Early initiation of treatment with statins in acute coronary syndromes
    • Olsson, A. G. and Schwartz, G. G. (2002) Early initiation of treatment with statins in acute coronary syndromes. Ann. Med. 34, 37-41.
    • (2002) Ann. Med. , vol.34 , pp. 37-41
    • Olsson, A.G.1    Schwartz, G.G.2
  • 72
    • 0035916233 scopus 로고    scopus 로고
    • Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization
    • Crisby, M., Nordin-Fredriksson, G., Shah, P. K., Yano J., Zhu J., Nilsson J. (2001) Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization. Circulation 103, 926-933.
    • (2001) Circulation , vol.103 , pp. 926-933
    • Crisby, M.1    Nordin-Fredriksson, G.2    Shah, P.K.3    Yano, J.4    Zhu, J.5    Nilsson, J.6
  • 73
    • 0001654669 scopus 로고    scopus 로고
    • Long term follow up of patients with mild coronary artery disease and endothelial dysfunction
    • Suwaidi, J. A., Hamaski, S., Higano, S. T., Nishimura, R. A., Holmes, D. R., Jr. et al. (2000) Long term follow up of patients with mild coronary artery disease and endothelial dysfunction. Circulation 101, 948-954.
    • (2000) Circulation , vol.101 , pp. 948-954
    • Suwaidi, J.A.1    Hamaski, S.2    Higano, S.T.3    Nishimura, R.A.4    Holmes Jr., D.R.5
  • 74
    • 0342424181 scopus 로고    scopus 로고
    • Prognostic impact of coronary vasodilator dysfunction on adverse long term outcome of coronary heart disease
    • Schachinger, V., Britten, M. B., and Zeiher, A. M. (2000) Prognostic impact of coronary vasodilator dysfunction on adverse long term outcome of coronary heart disease. Circulation 101, 1899-1906.
    • (2000) Circulation , vol.101 , pp. 1899-1906
    • Schachinger, V.1    Britten, M.B.2    Zeiher, A.M.3
  • 75
    • 0035838416 scopus 로고    scopus 로고
    • Prognostic significance of endothelial dysfunction in hypertensive patients
    • Perticone, F., Ceravolo, R., Pujia, A., Ventura G, Iacopino S, et al. (2001) Prognostic significance of endothelial dysfunction in hypertensive patients. Circulation 104, 191-196.
    • (2001) Circulation , vol.104 , pp. 191-196
    • Perticone, F.1    Ceravolo, R.2    Pujia, A.3    Ventura, G.4    Iacopino, S.5
  • 76
    • 0037007153 scopus 로고    scopus 로고
    • Risk stratification for postoperative cardiovascular events via noninvasive assessment of endothelial function: a prospective study
    • Gokce, N., Keaney, J. F., Jr., Hynter, L. M., Watkins M. T., Menzoian J. O., Vita J. A. (2002) Risk stratification for postoperative cardiovascular events via noninvasive assessment of endothelial function: a prospective study. Circulation 105, 1567-1572.
    • (2002) Circulation , vol.105 , pp. 1567-1572
    • Gokce, N.1    Keaney Jr., J.F.2    Hynter, L.M.3    Watkins, M.T.4    Menzoian, J.O.5    Vita, J.A.6
  • 77
  • 78
    • 0037434561 scopus 로고    scopus 로고
    • Circulating endothelial progenitor cells, vascular function, and cardiovascular risk
    • Hill, J., Zalos, G., Halcox, J. P. J., Schenke W. H., Waclawiw M. A., et al. (2003) Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N. Engl. J. Med. 348, 593-600.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 593-600
    • Hill, J.1    Zalos, G.2    Halcox, J.P.J.3    Schenke, W.H.4    Waclawiw, M.A.5
  • 79
    • 0034898468 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitor mobilizes bone marrow derived endothelial progenitor cells
    • Llevadot, J., Murasawa, S., Kureishi, Y., Uchida S., Masuda H., et al. (2001) HMG-CoA reductase inhibitor mobilizes bone marrow derived endothelial progenitor cells. J. Clin. Invest. 108, 399-405.
    • (2001) J. Clin. Invest. , vol.108 , pp. 399-405
    • Llevadot, J.1    Murasawa, S.2    Kureishi, Y.3    Uchida, S.4    Masuda, H.5
  • 80
    • 0034908652 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway
    • Dimmeler, S., Aicher, A., Vasa, M., Mildner-Rihm C., Adler K. (2001) HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway. J. Clin. Invest. 108, 391-397.
    • (2001) J. Clin. Invest. , vol.108 , pp. 391-397
    • Dimmeler, S.1    Aicher, A.2    Vasa, M.3    Mildner-Rihm, C.4    Adler, K.5
  • 81
    • 0035912855 scopus 로고    scopus 로고
    • Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease
    • Vasa, M., Fichtlscherer, S., Adler, K., Aicher A., Martin H., et al. (2001) Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease. Circulation 103, 2885-2890.
    • (2001) Circulation , vol.103 , pp. 2885-2890
    • Vasa, M.1    Fichtlscherer, S.2    Adler, K.3    Aicher, A.4    Martin, H.5
  • 82
    • 20844431696 scopus 로고    scopus 로고
    • Statin induced improvement of endothelial progenitor cell mobilization, myocardial neovascularization, left ventricular function, and survival after experimental myocardial infarction requires endothelial nitric oxide synthase
    • Landmesser, U., Engberding, N., Bahlmann, F. H., Schaefer A., Wiencke A., et al. (2004) Statin induced improvement of endothelial progenitor cell mobilization, myocardial neovascularization, left ventricular function, and survival after experimental myocardial infarction requires endothelial nitric oxide synthase. Circulation 110, 1933-1939.
    • (2004) Circulation , vol.110 , pp. 1933-1939
    • Landmesser, U.1    Engberding, N.2    Bahlmann, F.H.3    Schaefer, A.4    Wiencke, A.5
  • 83
    • 0033529618 scopus 로고    scopus 로고
    • Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization
    • Asahara, T., Masuda, H., Takahashi, T., Kalka C., Pastore C. (1999) Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ. Res. 85, 221-228.
    • (1999) Circ. Res. , vol.85 , pp. 221-228
    • Asahara, T.1    Masuda, H.2    Takahashi, T.3    Kalka, C.4    Pastore, C.5
  • 84
    • 0035814766 scopus 로고    scopus 로고
    • Therapeutic potential of ex vivo expanded endothelial progenitor cells for myocardial ischemia
    • Kawamoto, A., Gwon, H. C., Iwaguro, H., Yamaguchi J. I., Uchida S., et al. (2001) Therapeutic potential of ex vivo expanded endothelial progenitor cells for myocardial ischemia. Circulation 103, 634-637.
    • (2001) Circulation , vol.103 , pp. 634-637
    • Kawamoto, A.1    Gwon, H.C.2    Iwaguro, H.3    Yamaguchi, J.I.4    Uchida, S.5
  • 85
    • 0035044085 scopus 로고    scopus 로고
    • Neovascularization of ischemic myocardium by human bone-marrow derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function
    • Kocher, A. A., Schuster, M. D., Szabolcs, M. J., Takuma S., Burkhoff D., et al. (2001) Neovascularization of ischemic myocardium by human bone-marrow derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat. Med. 7, 430-436.
    • (2001) Nat. Med. , vol.7 , pp. 430-436
    • Kocher, A.A.1    Schuster, M.D.2    Szabolcs, M.J.3    Takuma, S.4    Burkhoff, D.5
  • 86
    • 0345276632 scopus 로고    scopus 로고
    • Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells
    • Aicher, A., Heeschen, C., Mildner-Rihm, C., Urbich C, Ihling C., (2003) Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells. Nat. Med. 9, 1370-1376.
    • (2003) Nat. Med. , vol.9 , pp. 1370-1376
    • Aicher, A.1    Heeschen, C.2    Mildner-Rihm, C.3    Urbich, C.4    Ihling, C.5
  • 87
    • 0037173080 scopus 로고    scopus 로고
    • Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrow derived endothelial progenitor cells
    • Walter, D. H., Ritting, K., Bahlmann, F. H., Kirchmair R., Silver M., et al. (2002) Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrow derived endothelial progenitor cells. Circulation 105, 3017-3024.
    • (2002) Circulation , vol.105 , pp. 3017-3024
    • Walter, D.H.1    Ritting, K.2    Bahlmann, F.H.3    Kirchmair, R.4    Silver, M.5
  • 89
    • 84869501803 scopus 로고    scopus 로고
    • Increased levels of circulating endothelial progenitor cells in patients with ischemic stroke treated with statins during acute phase
    • Sobrino, T., Blanco, M., Perez-Mato, M., Rodriguez-Yanez, M., and Castillo, J. (2012) Increased levels of circulating endothelial progenitor cells in patients with ischemic stroke treated with statins during acute phase. Eur. J. Neurol. 19, 1539-1546.
    • (2012) Eur. J. Neurol. , vol.19 , pp. 1539-1546
    • Sobrino, T.1    Blanco, M.2    Perez-Mato, M.3    Rodriguez-Yanez, M.4    Castillo, J.5
  • 90
    • 84863630296 scopus 로고    scopus 로고
    • Effect of pravastatin on endothelial function and endothelial progenitor cells in healthy postmenopausal women
    • Paradisi, G., Bracaglia, M., Basile, F., Di'Ipolito S., Di Nicuolo F., et al. (2012) Effect of pravastatin on endothelial function and endothelial progenitor cells in healthy postmenopausal women. Clin. Exp. Obstet. Gynecol. 39, 153-159.
    • (2012) Clin. Exp. Obstet. Gynecol. , vol.39 , pp. 153-159
    • Paradisi, G.1    Bracaglia, M.2    Basile, F.3    Di'Ipolito, S.4    Di Nicuolo, F.5
  • 91
    • 84865534163 scopus 로고    scopus 로고
    • Effects of preoperative short term use of atorvastatin on endothelial progenitor cells after coronary surgery: a randomized, controlled trial
    • Baran, C., Durdu, S., Dalva, K., Zaim Ç., Dogan A., et al. (2012) Effects of preoperative short term use of atorvastatin on endothelial progenitor cells after coronary surgery: a randomized, controlled trial. Stem Cell Rev. Rep. 8, 963-971.
    • (2012) Stem Cell Rev. Rep. , vol.8 , pp. 963-971
    • Baran, C.1    Durdu, S.2    Dalva, K.3    Zaim, C.4    Dogan, A.5
  • 92
    • 0346157997 scopus 로고    scopus 로고
    • Estrogen mediated, endothelial nitric oxide synthase-dependent mobilization of bone marrow derived endothelial progenitor cells contributes to reendothelialization after arterial injury
    • Iwakura, A., Luedemann, C., Shastry, S., Hanley A., Kearney M. (2003) Estrogen mediated, endothelial nitric oxide synthase-dependent mobilization of bone marrow derived endothelial progenitor cells contributes to reendothelialization after arterial injury. Circulation 108, 3115-3121.
    • (2003) Circulation , vol.108 , pp. 3115-3121
    • Iwakura, A.1    Luedemann, C.2    Shastry, S.3    Hanley, A.4    Kearney, M.5
  • 93
    • 0037007133 scopus 로고    scopus 로고
    • Statin attenuates increase in C-reactive protein during estrogen replacement therapy in postmenopausal women
    • Koh, K. K., Schenke, W. H., Waclawiw, M. A., Csako, G., and Cannon, R. O., III. (2002) Statin attenuates increase in C-reactive protein during estrogen replacement therapy in postmenopausal women. Circulation 105, 1531-1533.
    • (2002) Circulation , vol.105 , pp. 1531-1533
    • Koh, K.K.1    Schenke, W.H.2    Waclawiw, M.A.3    Csako, G.4    Cannon III, R.O.5
  • 94
    • 0034669457 scopus 로고    scopus 로고
    • Divergent effects of hormone therapy on serum markers of inflammation in postmenopausal women with coronary artery disease on appropriate medical management
    • Zanger, D., Yang, B. K., Ardans, J., Waclawiw, M. A., and Csako, G., et al. (2000) Divergent effects of hormone therapy on serum markers of inflammation in postmenopausal women with coronary artery disease on appropriate medical management. J. Am. Coll. Cardiol. 36, 1797-1802.
    • (2000) J. Am. Coll. Cardiol. , vol.36 , pp. 1797-1802
    • Zanger, D.1    Yang, B.K.2    Ardans, J.3    Waclawiw, M.A.4    Csako, G.5
  • 95
    • 1642576175 scopus 로고    scopus 로고
    • Physical training increases endothelial progenitor cells. Inhibits neointima formation, and enhances angiogenesis
    • Laufs, U., Werner, N., Link, A., et al. (2004) Physical training increases endothelial progenitor cells. Inhibits neointima formation, and enhances angiogenesis. Circulation 109, 220-226.
    • (2004) Circulation , vol.109 , pp. 220-226
    • Laufs, U.1    Werner, N.2    Link, A.3
  • 96
    • 58849100330 scopus 로고    scopus 로고
    • Microarray-based characterization of a colony assay used to investigate endothelial progenitor cells and relevance to endothelial function in humans
    • Desai, A., Glaser, A., Liu, D., Endres M., Wassmann S., et al. (2009) Microarray-based characterization of a colony assay used to investigate endothelial progenitor cells and relevance to endothelial function in humans. Arterioscler. Thromb. Vasc. Biol. 29, 121-127.
    • (2009) Arterioscler. Thromb. Vasc. Biol. , vol.29 , pp. 121-127
    • Desai, A.1    Glaser, A.2    Liu, D.3    Endres, M.4    Wassmann, S.5
  • 97
    • 78751521573 scopus 로고    scopus 로고
    • Transcriptional profiling of CD133+ cells in coronary artery disease and effects of exercise on gene expression
    • Liu, D., Glaser, A. P., Patibandla, S., Blum A., Munson P. J., et al. (2011) Transcriptional profiling of CD133+ cells in coronary artery disease and effects of exercise on gene expression. Cytotherapy 13, 227-236.
    • (2011) Cytotherapy , vol.13 , pp. 227-236
    • Liu, D.1    Glaser, A.P.2    Patibandla, S.3    Blum, A.4    Munson, P.J.5
  • 98
    • 84878607366 scopus 로고    scopus 로고
    • Atorvastatin enhance efficacy of mesenchymal stem cells treatment for swine myocardial infarction via activation of nitric oxide syntase
    • Song, L., Yang, Y. J., Dong, Q. T., Qian H. Y., Gao R. L., et al. (2013) Atorvastatin enhance efficacy of mesenchymal stem cells treatment for swine myocardial infarction via activation of nitric oxide syntase. PLoS One 8, e65702.
    • (2013) PLoS One , vol.8
    • Song, L.1    Yang, Y.J.2    Dong, Q.T.3    Qian, H.Y.4    Gao, R.L.5
  • 99
    • 84880176410 scopus 로고    scopus 로고
    • Vasculoprotective effects of combined endothelial progenitor cells and mesenchymal stem cells in diabetic wound care: their potential role in decreasing wound oxidative stress
    • doi.org/10.1155/2013/459196.
    • Sukpat, S., Isarasena, N., Wongphoom, J., Patumraj, S. (2013) Vasculoprotective effects of combined endothelial progenitor cells and mesenchymal stem cells in diabetic wound care: their potential role in decreasing wound oxidative stress. BioMed Res. Int. 2013, 8. doi.org/10.1155/2013/459196.
    • (2013) BioMed Res. Int. , vol.2013 , pp. 8
    • Sukpat, S.1    Isarasena, N.2    Wongphoom, J.3    Patumraj, S.4
  • 100
    • 84902541944 scopus 로고    scopus 로고
    • Cardiac cell based therapy: methods of application and delivery systems
    • 8th edn. (Grossman B and Baim D). Lippincott, Williams & Wilkins, Philadelphia PA 19103 USA.
    • Hare, J. M., Blum, A., and Heldman, A. W. (2013) Cardiac cell based therapy: methods of application and delivery systems. In Cardiac Catheterization, Angiography, and Intervention, 8th edn. (Grossman B and Baim D). pp. 871-889. Lippincott, Williams & Wilkins, Philadelphia PA 19103 USA.
    • (2013) Cardiac Catheterization, Angiography, and Intervention , pp. 871-889
    • Hare, J.M.1    Blum, A.2    Heldman, A.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.