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Volumn 115, Issue 8, 2014, Pages 1458-1466

Inhibition of AMPK/autophagy potentiates parthenolide-induced apoptosis in human breast cancer cells

Author keywords

ampk; apoptosis; autophagy; parthenolide; ros

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; PARTHENOLIDE; REACTIVE OXYGEN METABOLITE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; SESQUITERPENE;

EID: 84902439806     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24808     Document Type: Article
Times cited : (42)

References (37)
  • 1
    • 34447581119 scopus 로고    scopus 로고
    • Optimized production and concentration of lentiviral vectors containing large inserts
    • al Yacoub N, Romanowska M, Haritonova N, Foerster J,. 2007. Optimized production and concentration of lentiviral vectors containing large inserts. J Gene Med 9: 579-584.
    • (2007) J Gene Med , vol.9 , pp. 579-584
    • Al Yacoub, N.1    Romanowska, M.2    Haritonova, N.3    Foerster, J.4
  • 2
    • 84878707525 scopus 로고    scopus 로고
    • Manipulation of autophagy in cancer cells: An innovative strategy to fight drug resistance
    • Aredia F, Scovassi AI,. 2013. Manipulation of autophagy in cancer cells: An innovative strategy to fight drug resistance. Future Med Chem 5: 1009-1021.
    • (2013) Future Med Chem , vol.5 , pp. 1009-1021
    • Aredia, F.1    Scovassi, A.I.2
  • 4
    • 84859897794 scopus 로고    scopus 로고
    • Regulation of reactive oxygen species generation in cell signaling
    • Bae YS, Oh H, Rhee SG, Yoo YD,. 2011. Regulation of reactive oxygen species generation in cell signaling. Mol Cells 32: 491-509.
    • (2011) Mol Cells , vol.32 , pp. 491-509
    • Bae, Y.S.1    Oh, H.2    Rhee, S.G.3    Yoo, Y.D.4
  • 5
    • 80052218554 scopus 로고    scopus 로고
    • Parthenolide induces apoptosis and cell cycle arrest of human 5637 bladder cancer cells in vitro
    • Cheng G, Xie L,. 2011. Parthenolide induces apoptosis and cell cycle arrest of human 5637 bladder cancer cells in vitro. Molecules 16: 6758-6768.
    • (2011) Molecules , vol.16 , pp. 6758-6768
    • Cheng, G.1    Xie, L.2
  • 6
    • 7744235672 scopus 로고    scopus 로고
    • Death by design: Apoptosis, necrosis and autophagy
    • Edinger AL, Thompson CB,. 2004. Death by design: Apoptosis, necrosis and autophagy. Curr Opin Cell Biol 16: 663-669.
    • (2004) Curr Opin Cell Biol , vol.16 , pp. 663-669
    • Edinger, A.L.1    Thompson, C.B.2
  • 7
    • 79958700761 scopus 로고    scopus 로고
    • Autophagy interplay with apoptosis and cell cycle regulation in the growth inhibiting effect of resveratrol in glioma cells
    • Filippi-Chiela EC, Villodre ES, Zamin LL, Lenz G,. 2011. Autophagy interplay with apoptosis and cell cycle regulation in the growth inhibiting effect of resveratrol in glioma cells. PLoS ONE 6: e20849.
    • (2011) PLoS ONE , vol.6
    • Filippi-Chiela, E.C.1    Villodre, E.S.2    Zamin, L.L.3    Lenz, G.4
  • 10
    • 16844363378 scopus 로고    scopus 로고
    • The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells
    • Guzman ML, Rossi RM, Karnischky L, Li X, Peterson DR, Howard DS, Jordan CT,. 2005. The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells. Blood 105: 4163-4169.
    • (2005) Blood , vol.105 , pp. 4163-4169
    • Guzman, M.L.1    Rossi, R.M.2    Karnischky, L.3    Li, X.4    Peterson, D.R.5    Howard, D.S.6    Jordan, C.T.7
  • 11
    • 0036330651 scopus 로고    scopus 로고
    • N-Acetylcysteine, vitamin C and vitamin e diminish homocysteine thiolactone-induced apoptosis in human promyeloid HL-60 cells
    • Huang RF, Huang SM, Lin BS, Hung CY, Lu HT,. 2002. N-Acetylcysteine, vitamin C and vitamin E diminish homocysteine thiolactone-induced apoptosis in human promyeloid HL-60 cells. J Nutr 132: 2151-2156.
    • (2002) J Nutr , vol.132 , pp. 2151-2156
    • Huang, R.F.1    Huang, S.M.2    Lin, B.S.3    Hung, C.Y.4    Lu, H.T.5
  • 12
    • 84893677749 scopus 로고    scopus 로고
    • Autophagy in breast cancer and its implications for therapy
    • Jain K, Paranandi KS, Sridharan S, Basu A,. 2013. Autophagy in breast cancer and its implications for therapy. Am J Cancer Res 3: 251-265.
    • (2013) Am J Cancer Res , vol.3 , pp. 251-265
    • Jain, K.1    Paranandi, K.S.2    Sridharan, S.3    Basu, A.4
  • 13
    • 22244449287 scopus 로고    scopus 로고
    • Susceptibility of cholangiocarcinoma cells to parthenolide-induced apoptosis
    • Kim JH, Liu L, Lee SO, Kim YT, You KR, Kim DG,. 2005. Susceptibility of cholangiocarcinoma cells to parthenolide-induced apoptosis. Cancer Res 65: 6312-6320.
    • (2005) Cancer Res , vol.65 , pp. 6312-6320
    • Kim, J.H.1    Liu, L.2    Lee, S.O.3    Kim, Y.T.4    You, K.R.5    Kim, D.G.6
  • 14
    • 84883806509 scopus 로고    scopus 로고
    • Capsaicin stimulates glucose uptake in C2C12 muscle cells via the reactive oxygen species (ROS)/AMPK/p38 MAPK pathway
    • Kim SH, Hwang JT, Park HS, Kwon DY, Kim MS,. 2013. Capsaicin stimulates glucose uptake in C2C12 muscle cells via the reactive oxygen species (ROS)/AMPK/p38 MAPK pathway. Biochem Biophys Res Commun 439: 66-70.
    • (2013) Biochem Biophys Res Commun , vol.439 , pp. 66-70
    • Kim, S.H.1    Hwang, J.T.2    Park, H.S.3    Kwon, D.Y.4    Kim, M.S.5
  • 15
    • 84866480747 scopus 로고    scopus 로고
    • Parthenolide suppresses tumor growth in a xenograft model of colorectal cancer cells by inducing mitochondrial dysfunction and apoptosis
    • Kim SL, Trang KT, Kim SH, Kim IH, Lee SO, Lee ST, Kim DG, Kim SW,. 2012. Parthenolide suppresses tumor growth in a xenograft model of colorectal cancer cells by inducing mitochondrial dysfunction and apoptosis. Int J Oncol 41: 1547-1553.
    • (2012) Int J Oncol , vol.41 , pp. 1547-1553
    • Kim, S.L.1    Trang, K.T.2    Kim, S.H.3    Kim, I.H.4    Lee, S.O.5    Lee, S.T.6    Kim, D.G.7    Kim, S.W.8
  • 16
    • 34548077575 scopus 로고    scopus 로고
    • Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3
    • Kimura S, Noda T, Yoshimori T,. 2007. Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3. Autophagy 3: 452-460.
    • (2007) Autophagy , vol.3 , pp. 452-460
    • Kimura, S.1    Noda, T.2    Yoshimori, T.3
  • 17
    • 0029311312 scopus 로고
    • Feverfew: Chemistry and biological activity
    • Knight DW,. 1995. Feverfew: Chemistry and biological activity. Nat Prod Rep 12: 271-276.
    • (1995) Nat Prod Rep , vol.12 , pp. 271-276
    • Knight, D.W.1
  • 18
    • 84865967712 scopus 로고    scopus 로고
    • Sesquiterpene lactones as drugs with multiple targets in cancer treatment: Focus on parthenolide
    • Kreuger MR, Grootjans S, Biavatti MW, Vandenabeele P, D'Herde K,. 2012. Sesquiterpene lactones as drugs with multiple targets in cancer treatment: Focus on parthenolide. Anticancer Drugs 23: 883-896.
    • (2012) Anticancer Drugs , vol.23 , pp. 883-896
    • Kreuger, M.R.1    Grootjans, S.2    Biavatti, M.W.3    Vandenabeele, P.4    D'Herde, K.5
  • 19
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B, Kroemer G,. 2008. Autophagy in the pathogenesis of disease. Cell 132: 27-42.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 21
    • 34548188741 scopus 로고    scopus 로고
    • Self-eating and self-killing: Crosstalk between autophagy and apoptosis
    • Maiuri MC, Zalckvar E, Kimchi A, Kroemer G,. 2007. Self-eating and self-killing: Crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 8: 741-752.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 22
    • 84863619176 scopus 로고    scopus 로고
    • Parthenolide, a sesquiterpene lactone, expresses multiple anti-cancer and anti-inflammatory activities
    • Mathema VB, Koh YS, Thakuri BC, Sillanpaa M,. 2012. Parthenolide, a sesquiterpene lactone, expresses multiple anti-cancer and anti-inflammatory activities. Inflammation 35: 560-565.
    • (2012) Inflammation , vol.35 , pp. 560-565
    • Mathema, V.B.1    Koh, Y.S.2    Thakuri, B.C.3    Sillanpaa, M.4
  • 24
    • 84873546725 scopus 로고    scopus 로고
    • Life in the balance - A mechanistic view of the crosstalk between autophagy and apoptosis
    • Rubinstein AD, Kimchi A,. 2012. Life in the balance-A mechanistic view of the crosstalk between autophagy and apoptosis. J Cell Sci 125: 5259-5268.
    • (2012) J Cell Sci , vol.125 , pp. 5259-5268
    • Rubinstein, A.D.1    Kimchi, A.2
  • 25
    • 84884565721 scopus 로고    scopus 로고
    • AMP-activated protein kinase: A target for old drugs against diabetes and cancer
    • Russo GL, Russo M, Ungaro P,. 2013. AMP-activated protein kinase: A target for old drugs against diabetes and cancer. Biochem Pharmacol 86: 339-350.
    • (2013) Biochem Pharmacol , vol.86 , pp. 339-350
    • Russo, G.L.1    Russo, M.2    Ungaro, P.3
  • 27
    • 0005677775 scopus 로고
    • 3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes
    • Seglen PO, Gordon PB,. 1982. 3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes. Proc Natl Acad Sci USA 79: 1889-1892.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 1889-1892
    • Seglen, P.O.1    Gordon, P.B.2
  • 28
    • 84886076523 scopus 로고    scopus 로고
    • Activation of AMPK protects against hydrogen peroxide-induced osteoblast apoptosis through autophagy induction and NADPH maintenance: New implications for osteonecrosis treatment?
    • She C, Zhu LQ, Zhen YF, Wang XD, Dong QR,. 2014. Activation of AMPK protects against hydrogen peroxide-induced osteoblast apoptosis through autophagy induction and NADPH maintenance: New implications for osteonecrosis treatment? Cell Signal 26: 1-8.
    • (2014) Cell Signal , vol.26 , pp. 1-8
    • She, C.1    Zhu, L.Q.2    Zhen, Y.F.3    Wang, X.D.4    Dong, Q.R.5
  • 29
    • 80051580618 scopus 로고    scopus 로고
    • Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths
    • Siegel R, Ward E, Brawley O, Jemal A,. 2011. Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin 61: 212-236.
    • (2011) CA Cancer J Clin , vol.61 , pp. 212-236
    • Siegel, R.1    Ward, E.2    Brawley, O.3    Jemal, A.4
  • 30
    • 83255193986 scopus 로고    scopus 로고
    • Role of the AMP-activated protein kinase (AMPK) signaling pathway in the orexigenic effects of endogenous ghrelin
    • Verhulst PJ, Janssen S, Tack J, Depoortere I,. 2012. Role of the AMP-activated protein kinase (AMPK) signaling pathway in the orexigenic effects of endogenous ghrelin. Regul Pept 173: 27-35.
    • (2012) Regul Pept , vol.173 , pp. 27-35
    • Verhulst, P.J.1    Janssen, S.2    Tack, J.3    Depoortere, I.4
  • 31
    • 33845363571 scopus 로고    scopus 로고
    • Parthenolide-induced apoptosis in multiple myeloma cells involves reactive oxygen species generation and cell sensitivity depends on catalase activity
    • Wang W, Adachi M, Kawamura R, Sakamoto H, Hayashi T, Ishida T, Imai K, Shinomura Y,. 2006. Parthenolide-induced apoptosis in multiple myeloma cells involves reactive oxygen species generation and cell sensitivity depends on catalase activity. Apoptosis 11: 2225-2235.
    • (2006) Apoptosis , vol.11 , pp. 2225-2235
    • Wang, W.1    Adachi, M.2    Kawamura, R.3    Sakamoto, H.4    Hayashi, T.5    Ishida, T.6    Imai, K.7    Shinomura, Y.8
  • 32
    • 0037064130 scopus 로고    scopus 로고
    • Oxidative stress-mediated apoptosis. The anticancer effect of the sesquiterpene lactone parthenolide
    • Wen J, You KR, Lee SY, Song CH, Kim DG,. 2002. Oxidative stress-mediated apoptosis. The anticancer effect of the sesquiterpene lactone parthenolide. J Biol Chem 277: 38954-38964.
    • (2002) J Biol Chem , vol.277 , pp. 38954-38964
    • Wen, J.1    You, K.R.2    Lee, S.Y.3    Song, C.H.4    Kim, D.G.5
  • 33
    • 84878363798 scopus 로고    scopus 로고
    • Apoptosis-mediated cytotoxic effects of parthenolide and the new synthetic analog MZ-6 on two breast cancer cell lines
    • Wyrebska A, Szymanski J, Gach K, Piekielna J, Koszuk J, Janecki T, Janecka A,. 2013. Apoptosis-mediated cytotoxic effects of parthenolide and the new synthetic analog MZ-6 on two breast cancer cell lines. Mol Biol Rep 40: 1655-1663.
    • (2013) Mol Biol Rep , vol.40 , pp. 1655-1663
    • Wyrebska, A.1    Szymanski, J.2    Gach, K.3    Piekielna, J.4    Koszuk, J.5    Janecki, T.6    Janecka, A.7
  • 34
    • 18044376489 scopus 로고    scopus 로고
    • Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-kappa B pathway in pancreatic carcinoma cells
    • Yip-Schneider MT, Nakshatri H, Sweeney CJ, Marshall MS, Wiebke EA, Schmidt CM,. 2005. Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-kappa B pathway in pancreatic carcinoma cells. Mol Cancer Ther 4: 587-594.
    • (2005) Mol Cancer Ther , vol.4 , pp. 587-594
    • Yip-Schneider, M.T.1    Nakshatri, H.2    Sweeney, C.J.3    Marshall, M.S.4    Wiebke, E.A.5    Schmidt, C.M.6
  • 35
    • 84880382817 scopus 로고    scopus 로고
    • Visualization of caspase-3-like activity in cells using a genetically encoded fluorescent biosensor activated by protein cleavage
    • Zhang J, Wang X, Cui W, Wang W, Zhang H, Liu L, Zhang Z, Li Z, Ying G, Zhang N, Li B,. 2013. Visualization of caspase-3-like activity in cells using a genetically encoded fluorescent biosensor activated by protein cleavage. Nat Commun 4: 2157.
    • (2013) Nat Commun , vol.4 , pp. 2157
    • Zhang, J.1    Wang, X.2    Cui, W.3    Wang, W.4    Zhang, H.5    Liu, L.6    Zhang, Z.7    Li, Z.8    Ying, G.9    Zhang, N.10    Li, B.11
  • 36
    • 2442538125 scopus 로고    scopus 로고
    • Critical roles of intracellular thiols and calcium in parthenolide-induced apoptosis in human colorectal cancer cells
    • Zhang S, Ong CN, Shen HM,. 2004. Critical roles of intracellular thiols and calcium in parthenolide-induced apoptosis in human colorectal cancer cells. Cancer Lett 208: 143-153.
    • (2004) Cancer Lett , vol.208 , pp. 143-153
    • Zhang, S.1    Ong, C.N.2    Shen, H.M.3
  • 37
    • 34447319405 scopus 로고    scopus 로고
    • Parthenolide induces significant apoptosis and production of reactive oxygen species in high-risk pre-B leukemia cells
    • Zunino SJ, Ducore JM, Storms DH,. 2007. Parthenolide induces significant apoptosis and production of reactive oxygen species in high-risk pre-B leukemia cells. Cancer Lett 254: 119-127.
    • (2007) Cancer Lett , vol.254 , pp. 119-127
    • Zunino, S.J.1    Ducore, J.M.2    Storms, D.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.