Apoptosis-mediated cytotoxic effects of parthenolide and the new synthetic analog MZ-6 on two breast cancer cell lines

Molecular Biology Reports

Volumn 40, Issue 2, 2013, Pages 1655-1663

  Wyrȩbska, Anna ^a   Szymański, Jacek ^a   Gach, Katarzyna ^a   Piekielna, Justyna ^a   Koszuk, Jacek ^b   Janecki, Tomasz ^b   Janecka, Anna ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

^b LODZ UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

Methylene lactones; Apoptosis; Breast cancer; Cell cycle arrest

Indexed keywords

3 ISOPROPYL 2 METHYL 4 METHYLENEISOXAZOLIDIN 5 ONE; ALPHA METHYLENE GAMMA LACTONE DERIVATIVE; ANTINEOPLASTIC AGENT; MALONALDEHYDE; MESSENGER RNA; MZ 6; PARTHENOLIDE; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BAX GENE; BCL 2 GENE; BREAST CANCER; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG STRUCTURE; G1 PHASE CELL CYCLE CHECKPOINT; GAPDH GENE; GENE; HUMAN; HUMAN CELL; LIPID PEROXIDATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BREAST NEOPLASMS; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; CELL SHAPE; DNA REPLICATION; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; ISOXAZOLES; LIPID PEROXIDATION; MCF-7 CELLS; OXIDATIVE STRESS; SESQUITERPENES; TRANSCRIPTION, GENETIC;

TANACETUM PARTHENIUM;

EID: 84878363798     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-2215-6     Document Type: Article

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