Parthenolide-induced apoptosis in multiple myeloma cells involves reactive oxygen species generation and cell sensitivity depends on catalase activity

Apoptosis

Volumn 11, Issue 12, 2006, Pages 2225-2235

  Wang, Wei ^a   Adachi, Masaaki ^a,b   Kawamura, Rina ^a   Sakamoto, Hiroki ^a   Hayashi, Toshiaki ^b   Ishida, Tadao ^b   Imai, Kohzoh ^b   Shinomura, Yasuhisa ^b  

^a SAPPORO MEDICAL UNIVERSITY   (Japan)

^b SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Catalase; Multiple myeloma; NADPH oxidase; Parthenolide; ROS

Indexed keywords

ACETYLCYSTEINE; AMITROLE; CATALASE; CD38 ANTIGEN; PARTHENOLIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; CELL DEATH; CELL LINE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; ENZYME INHIBITOR INTERACTION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LYMPHOCYTE; MULTIPLE MYELOMA; OXIDATIVE STRESS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ACETYLCYSTEINE; AGED, 80 AND OVER; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIOXIDANTS; APOPTOSIS; CATALASE; CELL SURVIVAL; ENZYME INHIBITORS; HUMANS; MULTIPLE MYELOMA; ONIUM COMPOUNDS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SESQUITERPENES;

EID: 33845363571     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-006-0287-2     Document Type: Article

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