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Volumn 13, Issue 2, 2014, Pages 459-469

Antineoplastic potential of curcumin (cooperative study in Bulgaria and Germany)

Author keywords

Anticlastogenic effect; Antineoplastic activity; CTCL; Curcumin; Topical treatment

Indexed keywords

AMINOPEPTIDASE; ANTINEOPLASTIC AGENT; CASPASE; CURCUMIN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DNA; GLUTATHIONE; I KAPPA B; MICROSOMAL AMINOPEPTIDASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA;

EID: 84902368943     PISSN: 15687767     EISSN: 1572980X     Source Type: Journal    
DOI: 10.1007/s11101-014-9351-7     Document Type: Article
Times cited : (9)

References (91)
  • 1
    • 0032991568 scopus 로고    scopus 로고
    • Curcumin inhibition of inflammatory cytokine production by human peripheral blood monocytes and alveolar macrophages
    • Abe Y, Hashimoto S, Horie T (1999) Curcumin inhibition of inflammatory cytokine production by human peripheral blood monocytes and alveolar macrophages. Pharmacol Res 39(1):41-47
    • (1999) Pharmacol Res , vol.39 , Issue.1 , pp. 41-47
    • Abe, Y.1    Hashimoto, S.2    Horie, T.3
  • 2
    • 55949117806 scopus 로고    scopus 로고
    • Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases
    • Aggarwal BB, Harikumar KB (2009) Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases. Int J Biochem Cell Biol 41(1):40-59
    • (2009) Int J Biochem Cell Biol , vol.41 , Issue.1 , pp. 40-59
    • Aggarwal, B.B.1    Harikumar, K.B.2
  • 3
    • 59349120231 scopus 로고    scopus 로고
    • Pharmacological basis for the role of curcumin in chronic diseases: An age-old spice with modern targets
    • Aggarwal BB, Sung B (2009) Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets. Trends Pharmacol Sci 30(2):85-94
    • (2009) Trends Pharmacol Sci , vol.30 , Issue.2 , pp. 85-94
    • Aggarwal, B.B.1    Sung, B.2
  • 5
    • 30044446136 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation
    • DOI 10.1124/mol.105.017400
    • Aggarwal S, Ichikawa H, Takada Y et al (2006b) Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation. Mol Pharmacol 69(1):195-206 (Pubitemid 43048906)
    • (2006) Molecular Pharmacology , vol.69 , Issue.1 , pp. 195-206
    • Aggarwal, S.1    Ichikawa, H.2    Takada, Y.3    Sandur, S.K.4    Shishodia, S.5    Aggarwal, B.B.6
  • 7
    • 37549051274 scopus 로고    scopus 로고
    • Bioavailability of curcumin: Problems and promises
    • Anand P, Kunnumakkara AB, Newman RA et al (2007) Bioavailability of curcumin: problems and promises. Mol Pharm 4(6):807-818
    • (2007) Mol Pharm , vol.4 , Issue.6 , pp. 807-818
    • Anand, P.1    Kunnumakkara, A.B.2    Newman, R.A.3
  • 8
    • 55949084512 scopus 로고    scopus 로고
    • Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature
    • Anand P, Thomas SG, Kunnumakkara AB et al (2008) Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature. Biochem Pharmacol 76(11):1590-1611
    • (2008) Biochem Pharmacol , vol.76 , Issue.11 , pp. 1590-1611
    • Anand, P.1    Thomas, S.G.2    Kunnumakkara, A.B.3
  • 9
    • 34347238938 scopus 로고    scopus 로고
    • Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: Role of akt and extracellular signal-regulated kinase signaling pathways
    • DOI 10.1124/mol.106.033167
    • Aoki H, Takada Y, Kondo S et al (2007) Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways. Mol Pharmacol 72(1):29-39 (Pubitemid 46998522)
    • (2007) Molecular Pharmacology , vol.72 , Issue.1 , pp. 29-39
    • Aoki, H.1    Takada, Y.2    Kondo, S.3    Sawaya, R.4    Aggarwal, B.B.5    Kondo, Y.6
  • 10
    • 34250370973 scopus 로고    scopus 로고
    • Curcumin suppresses AP1 transcription factor-dependent differentiation and activates apoptosis in human epidermal keratinocytes
    • DOI 10.1074/jbc.M606003200
    • Balasubramanian S, Eckert RL (2007) Curcumin suppresses AP1 transcription factor-dependent differentiation and activates apoptosis in human epidermal keratinocytes. J Biol Chem 282(9):6707-6715 (Pubitemid 47100891)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.9 , pp. 6707-6715
    • Balasubramanian, S.1    Eckert, R.L.2
  • 13
    • 0141955061 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) inhibits constitutive and IL-6-inducible STAT3 phosphorylation in human multiple myeloma cells
    • Bharti AC, Donato N, Aggarwal BB (2003) Curcumin (diferuloylmethane) inhibits constitutive and IL-6-inducible STAT3 phosphorylation in human multiple myeloma cells. J Immunol 171(7):3863-3871 (Pubitemid 37254592)
    • (2003) Journal of Immunology , vol.171 , Issue.7 , pp. 3863-3871
    • Bharti, A.C.1    Donato, N.2    Aggarwal, B.B.3
  • 14
    • 1842579486 scopus 로고    scopus 로고
    • + cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis
    • DOI 10.1182/blood-2003-06-2151
    • Bharti AC, Shishodia S, Reuben JM et al (2004a) Nuclear factor-kappaB and STAT3 are constitutively active in CD138+ cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis. Blood 103(8):3175-3184 (Pubitemid 38451696)
    • (2004) Blood , vol.103 , Issue.8 , pp. 3175-3184
    • Bharti, A.C.1    Shishodia, S.2    Reuben, J.M.3    Weber, D.4    Alexanian, R.5    Raj-Vadhan, S.6    Estrov, Z.7    Talpaz, M.8    Aggarwal, B.B.9
  • 15
    • 2442607612 scopus 로고    scopus 로고
    • Curcumin (Diferuloylmethane) Inhibits Receptor Activator of NF-kappaB Ligand-Induced NF-kappaB Activation in Osteoclast Precursors and Suppresses Osteoclastogenesis
    • Bharti AC, Takada Y, Aggarwal BB (2004b) Curcumin (diferuloylmethane) inhibits receptor activator of NF-kappa B ligand-induced NF-kappa B activation in osteoclast precursors and suppresses osteoclastogenesis. J Immunol 172(10):5940-5947 (Pubitemid 38621193)
    • (2004) Journal of Immunology , vol.172 , Issue.10 , pp. 5940-5947
    • Bharti, A.C.1    Takada, Y.2    Aggarwal, B.B.3
  • 16
    • 34447530391 scopus 로고    scopus 로고
    • Curcumin prevents tumor-induced T cell apoptosis through Stat-5a-mediated Bcl-2 induction
    • DOI 10.1074/jbc.M608189200
    • Bhattacharyya S, Mandal D, Saha B et al (2007) Curcumin prevents tumor-induced T cell apoptosis through Stat-5a-mediated Bcl-2 induction. J Biol Chem 282(22):15954-15964 (Pubitemid 47100378)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.22 , pp. 15954-15964
    • Bhattacharyya, S.1    Mandal, D.2    Saha, B.3    Sen, G.S.4    Das, T.5    Sa, G.6
  • 18
    • 33744805811 scopus 로고    scopus 로고
    • Mitochondrial and nuclear DNA damage induced by curcumin in human hepatoma G2 cells
    • DOI 10.1093/toxsci/kfj153
    • Cao J, Jia L, Zhou H-M et al (2006) Mitochondrial and nuclear DNA damage induced by curcumin in human hepatoma G2 cells. Toxicol Sci 91(2):476-483 (Pubitemid 43827300)
    • (2006) Toxicological Sciences , vol.91 , Issue.2 , pp. 476-483
    • Cao, J.1    Jia, L.2    Zhou, H.-M.3    Liu, Y.4    Zhong, L.-F.5
  • 19
    • 33747470228 scopus 로고    scopus 로고
    • Targeting constitutive and interleukin-6-inducible signal transducers and activators of transcription 3 pathway in head and neck squamous cell carcinoma cells by curcumin (diferuloylmethane)
    • DOI 10.1002/ijc.21967
    • Chakravarti N, Myers JN, Aggarwal BB (2006) Targeting constitutive and interleukin-6-inducible signal transducers and activators of transcription 3 pathway in head and neck squamous cell carcinoma cells by curcumin (diferuloylmethane). Int J Cancer 119(6):1268-1275 (Pubitemid 44258799)
    • (2006) International Journal of Cancer , vol.119 , Issue.6 , pp. 1268-1275
    • Chakravarti, N.1    Myers, J.N.2    Aggarwal, B.B.3
  • 20
    • 31344440514 scopus 로고    scopus 로고
    • Curcumin and its analogues as potent inhibitors of low density lipoprotein oxidation: H-atom abstraction from the phenolic groups and possible involvement of the 4-hydroxy-3-methoxyphenyl groups
    • DOI 10.1016/j.freeradbiomed.2005.09.008, PII S0891584905005265
    • Chen W-F, Deng S-L, Zhou B et al (2006) Curcumin and its analogues as potent inhibitors of low density lipoprotein oxidation: H-atom abstraction from the phenolic groups and possible involvement of the 4-hydroxy-3-methoxyphenyl groups. Free Radic Biol Med 40(3):526-535 (Pubitemid 43139688)
    • (2006) Free Radical Biology and Medicine , vol.40 , Issue.3 , pp. 526-535
    • Chen, W.-F.1    Deng, S.-L.2    Zhou, B.3    Yang, L.4    Liu, Z.-L.5
  • 21
    • 33947532054 scopus 로고    scopus 로고
    • Curcumin attenuates the expression of IL-1beta, IL-6, and TNF-alpha as well as cyclin E in TNF-alpha-treated HaCaT cells; NF-kappaB and MAPKs as potential upstream targets
    • Cho JW, Lee KS, Kim C (2007) Curcumin attenuates the expression of IL-1beta, IL-6, and TNF-alpha as well as cyclin E in TNF-alpha-treated HaCaT cells; NF-kappaB and MAPKs as potential upstream targets. Int J Mol Med 19(3):469-474
    • (2007) Int J Mol Med , vol.19 , Issue.3 , pp. 469-474
    • Cho, J.W.1    Lee, K.S.2    Kim, C.3
  • 22
    • 34447558598 scopus 로고    scopus 로고
    • Incidence of cutaneous T-cell lymphoma in the United States, 1973-2002
    • DOI 10.1001/archderm.143.7.854
    • Criscione VD, Weinstock MA (2007) Incidence of cutaneous T-cell lymphoma in the United States, 1973-2002. Arch Dermatol 143(7):854-859 (Pubitemid 47076482)
    • (2007) Archives of Dermatology , vol.143 , Issue.7 , pp. 854-859
    • Criscione, V.D.1    Weinstock, M.A.2
  • 23
    • 34347221946 scopus 로고    scopus 로고
    • Curcumin suppresses growth and chemoresistance of human glioblastoma cells via AP-1 and NFkappaB transcription factors
    • DOI 10.1111/j.1471-4159.2007.04633.x
    • Dhandapani KM, Mahesh VB, Brann DW (2007) Curcumin suppresses growth and chemoresistance of human glioblastoma cells via AP-1 and NFkappaB transcription factors. J Neurochem 102(2):522-538 (Pubitemid 47000605)
    • (2007) Journal of Neurochemistry , vol.102 , Issue.2 , pp. 522-538
    • Dhandapani, K.M.1    Mahesh, V.B.2    Brann, D.W.3
  • 25
    • 21644477778 scopus 로고    scopus 로고
    • Thioredoxin reductase is irreversibly modified by curcumin: A novel molecular mechanism for its anticancer activity
    • DOI 10.1074/jbc.M414645200
    • Fang J, Lu J, Holmgren A (2005) Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activity. J Biol Chem 280(26):25284-25290 (Pubitemid 40934623)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.26 , pp. 25284-25290
    • Fang, J.1    Lu, J.2    Holmgren, A.3
  • 26
    • 30944443965 scopus 로고    scopus 로고
    • Curcumin blocks fibrosis in anti-Thy 1 glomerulonephritis through up-regulation of heme oxygenase 1
    • DOI 10.1111/j.1523-1755.2005.00658.x, PII 4494848
    • Gaedeke J, Noble NA, Border WA (2005) Curcumin blocks fibrosis in anti-Thy 1 glomerulonephritis through up-regulation of heme oxygenase 1. Kidney Int 68(5):2042-2049 (Pubitemid 43117779)
    • (2005) Kidney International , vol.68 , Issue.5 , pp. 2042-2049
    • Gaedeke, J.1    Noble, N.A.2    Border, W.A.3
  • 27
    • 59449089202 scopus 로고    scopus 로고
    • Effects of curcumin on ethanol-induced hepatocyte necrosis and apoptosis: Implication of lipid peroxidation and cytochrome c
    • Ghoneim AI (2009) Effects of curcumin on ethanol-induced hepatocyte necrosis and apoptosis: implication of lipid peroxidation and cytochrome c. Naunyn Schmiedebergs Arch Pharmacol 379(1):47-60
    • (2009) Naunyn Schmiedebergs Arch Pharmacol , vol.379 , Issue.1 , pp. 47-60
    • Ghoneim, A.I.1
  • 28
    • 77958011209 scopus 로고    scopus 로고
    • Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs
    • Goel A, Aggarwal BB (2010) Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs. Nutr Cancer 62(7):919-930
    • (2010) Nutr Cancer , vol.62 , Issue.7 , pp. 919-930
    • Goel, A.1    Aggarwal, B.B.2
  • 30
    • 34848854771 scopus 로고    scopus 로고
    • MD-2 as the target of curcumin in the inhibition of response to LPS
    • DOI 10.1189/jlb.1206727
    • Gradisar H, Keber MM, Pristovsek P et al (2007) MD-2 as the target of curcumin in the inhibition of response to LPS. J Leukoc Biol 82(4):968-974 (Pubitemid 47511057)
    • (2007) Journal of Leukocyte Biology , vol.82 , Issue.4 , pp. 968-974
    • Gradisar, H.1    Keber, M.M.2    Pristovsek, P.3    Jerala, R.4
  • 31
    • 84863097727 scopus 로고    scopus 로고
    • A particular expression pattern of CD13 epitope 7H5 in chronic lymphocytic leukaemia-a possible new therapeutic target
    • Guenova ML, Michova A, Balatzenko GN et al (2012) A particular expression pattern of CD13 epitope 7H5 in chronic lymphocytic leukaemia-a possible new therapeutic target. Hematology 17(3):132-139
    • (2012) Hematology , vol.17 , Issue.3 , pp. 132-139
    • Guenova, M.L.1    Michova, A.2    Balatzenko, G.N.3
  • 32
    • 77957592789 scopus 로고    scopus 로고
    • Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals
    • Gupta SC, Kim JH, Prasad S et al (2010) Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals. Cancer Metastasis Rev 29(3):405-434
    • (2010) Cancer Metastasis Rev , vol.29 , Issue.3 , pp. 405-434
    • Gupta, S.C.1    Kim, J.H.2    Prasad, S.3
  • 33
    • 79958848355 scopus 로고    scopus 로고
    • Role of nuclear factor j B-mediated inflammatory pathways in cancer-related symptoms and their regulation by nutritional agents
    • Gupta SC, Kim JH, Kannappan R et al (2011a) Role of nuclear factor j B-mediated inflammatory pathways in cancer-related symptoms and their regulation by nutritional agents. Exp Biol Med 236(6):658-671
    • (2011) Exp Biol Med , vol.236 , Issue.6 , pp. 658-671
    • Gupta, S.C.1    Kim, J.H.2    Kannappan, R.3
  • 34
    • 81355142057 scopus 로고    scopus 로고
    • Multitargeting by curcumin as revealed by molecular interaction studies
    • Gupta SC, Prasad S, Kim JH et al (2011b) Multitargeting by curcumin as revealed by molecular interaction studies. Nat Prod Rep 28(12):1937-1955
    • (2011) Nat Prod Rep , vol.28 , Issue.12 , pp. 1937-1955
    • Gupta, S.C.1    Prasad, S.2    Kim, J.H.3
  • 35
    • 84863115185 scopus 로고    scopus 로고
    • Discovery of curcumin, a component of golden spice, and its miraculous biological activities
    • Gupta SC, Patchva S, Koh W et al (2012) Discovery of curcumin, a component of golden spice, and its miraculous biological activities. Clin Exp Pharmacol Physiol 39(3):283-299
    • (2012) Clin Exp Pharmacol Physiol , vol.39 , Issue.3 , pp. 283-299
    • Gupta, S.C.1    Patchva, S.2    Koh, W.3
  • 36
    • 44749093175 scopus 로고    scopus 로고
    • Curcumin: From ancient medicine to current clinical trials
    • Hatcher H, Planalp R, Cho J et al (2008) Curcumin: from ancient medicine to current clinical trials. Cell Mol Life Sci 65(11):1631-1652
    • (2008) Cell Mol Life Sci , vol.65 , Issue.11 , pp. 1631-1652
    • Hatcher, H.1    Planalp, R.2    Cho, J.3
  • 37
    • 0026045073 scopus 로고
    • Suppression of c-Jun/AP-1 activation by an inhibitor of tumor promotion in mouse fibroblast cells
    • Huang TS, Lee SC, Lin JK (1991) Suppression of c-Jun/AP-1 activation by an inhibitor of tumor promotion in mouse fibroblast cells. Proc Natl Acad Sci USA 88(12):5292-5296
    • (1991) Proc Natl Acad Sci USA , vol.88 , Issue.12 , pp. 5292-5296
    • Huang, T.S.1    Lee, S.C.2    Lin, J.K.3
  • 38
    • 33846889718 scopus 로고    scopus 로고
    • "Spicing up" of the immune system by curcumin
    • Jagetia GC, Aggarwal BB (2007) "Spicing up" of the immune system by curcumin. J Clin Immunol 27(1):19-35
    • (2007) J Clin Immunol , vol.27 , Issue.1 , pp. 19-35
    • Jagetia, G.C.1    Aggarwal, B.B.2
  • 39
    • 84861091081 scopus 로고    scopus 로고
    • Novel therapeutic agents for cutaneous T-Cell lymphoma
    • Jain S, Zain J, O'Connor O (2012) Novel therapeutic agents for cutaneous T-Cell lymphoma. J Hematol Oncol 5:24
    • (2012) J Hematol Oncol , vol.5 , pp. 24
    • Jain, S.1    Zain, J.2    O'Connor, O.3
  • 40
    • 42449117212 scopus 로고    scopus 로고
    • The chemopreventive agent curcumin is a potent radiosensitizer of human cervical tumor cells via increased reactive oxygen species production and overactivation of the mitogen-activated protein kinase pathway
    • DOI 10.1124/mol.107.043554
    • Javvadi P, Segan AT, Tuttle SW et al (2008) The chemopreventive agent curcumin is a potent radiosensitizer of human cervical tumor cells via increased reactive oxygen species production and overactivation of the mitogen-activated protein kinase pathway. Mol Pharmacol 73(5):1491-1501 (Pubitemid 351574839)
    • (2008) Molecular Pharmacology , vol.73 , Issue.5 , pp. 1491-1501
    • Javvadi, P.1    Segan, A.T.2    Tuttle, S.W.3    Koumenis, C.4
  • 41
    • 34247855828 scopus 로고    scopus 로고
    • Antioxidative effects of plant polyphenols: From protection of G protein signaling to prevention of age-related pathologies
    • DOI 10.1196/annals.1397.048, Signal Transduction Pathways, Part C: Cell Signaling in Health and Disease
    • Jefremov V, Zilmer M, Zilmer K et al (2007) Antioxidative effects of plant polyphenols: from protection of G protein signaling to prevention of age-related pathologies. Ann N Y Acad Sci 1095:449-457 (Pubitemid 47092475)
    • (2007) Annals of the New York Academy of Sciences , vol.1095 , pp. 449-457
    • Jefremov, V.1    Zilmer, M.2    Zilmer, K.3    Bogdanovic, N.4    Karelson, E.5
  • 42
    • 0028134769 scopus 로고
    • Role of capsaicin, curcumin and dietary n-3 fatty acids in lowering the generation of reactive oxygen species in rat peritoneal macrophages
    • Joe B, Lokesh BR (1994) Role of capsaicin, curcumin and dietary n-3 fatty acids in lowering the generation of reactive oxygen species in rat peritoneal macrophages. Biochim Biophys Acta 1224(2):255-263
    • (1994) Biochim Biophys Acta , vol.1224 , Issue.2 , pp. 255-263
    • Joe, B.1    Lokesh, B.R.2
  • 43
    • 14544300204 scopus 로고    scopus 로고
    • The role of p53 & anaplastic lymphoma kinase genes in the progression of cutaneous CD30+ lymphoproliferative diseases
    • Kapur S, Tiemann M, Menke MA et al (2005) The role of p53 and anaplastic lymphoma kinase genes in the progression of cutaneous CD30(?) lymphoproliferative diseases. Indian J Med Res 121(1):46-54 (Pubitemid 40305575)
    • (2005) Indian Journal of Medical Research , vol.121 , Issue.1 , pp. 46-54
    • Kapur, S.1    Tiemann, M.2    Menke, M.A.O.H.3    Schubert, C.4    Parwaresch, R.5
  • 45
    • 0042964834 scopus 로고    scopus 로고
    • Long-term outcome of 525 patients with mycosis fungoides and Sézary syndrome: Clinical prognostic factors and risk for disease progression
    • DOI 10.1001/archderm.139.7.857
    • Kim YH, Liu HL, Mraz-Gernhard S et al (2003) Long-term outcome of 525 patients with mycosis fungoides and Sezary syndrome: clinical prognostic factors and risk for disease progression. Arch Dermatol 139(7):857-866 (Pubitemid 36898920)
    • (2003) Archives of Dermatology , vol.139 , Issue.7 , pp. 857-866
    • Kim, Y.H.1    Liu, H.L.2    Mraz-Gernhard, S.3    Varghese, A.4    Hoppe, R.T.5
  • 46
    • 47249092205 scopus 로고    scopus 로고
    • Curcumin stimulates proliferation of embryonic neural progenitor cells and neurogenesis in the adult hippocampus
    • Kim SJ, Son TG, Park HR et al (2008) Curcumin stimulates proliferation of embryonic neural progenitor cells and neurogenesis in the adult hippocampus. J Biol Chem 283(21):14497-14505
    • (2008) J Biol Chem , vol.283 , Issue.21 , pp. 14497-14505
    • Kim, S.J.1    Son, T.G.2    Park, H.R.3
  • 47
    • 0030870818 scopus 로고    scopus 로고
    • Curcumin inhibition of Dermatophagoides farinea-induced interleukin-5 (IL-5) and granulocyte macrophage-colony stimulating factor (GM-CSF) production by lymphocytes from bronchial asthmatics
    • DOI 10.1016/S0006-2952(97)00220-7, PII S0006295297002207
    • Kobayashi T, Hashimoto S, Horie T (1997) Curcumin inhibition of Dermatophagoides farinea-induced interleukin-5 (IL-5) and granulocyte macrophage-colony stimulating factor (GM-CSF) production by lymphocytes from bronchial asthmatics. Biochem Pharmacol 54(7):819-824 (Pubitemid 27404683)
    • (1997) Biochemical Pharmacology , vol.54 , Issue.7 , pp. 819-824
    • Kobayashi, T.1    Hashimoto, S.2    Horie, T.3
  • 49
    • 84902358324 scopus 로고    scopus 로고
    • Will human urinary bladder carcinoma respond to treatment with alkylphosphocholines and curcumin?
    • Konstantinov SM, Kostovski A, Berger MR (2002) Will human urinary bladder carcinoma respond to treatment with alkylphosphocholines and curcumin? Facta Univ Ser Med Biol 9(1):111-113
    • (2002) Facta Univ Ser Med Biol , vol.9 , Issue.1 , pp. 111-113
    • Konstantinov, S.M.1    Kostovski, A.2    Berger, M.R.3
  • 51
    • 34248573808 scopus 로고    scopus 로고
    • Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products
    • DOI 10.1158/0008-5472.CAN-06-4257
    • Kunnumakkara AB, Guha S, Krishnan S et al (2007) Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products. Cancer Res 67(8):3853-3861 (Pubitemid 46762173)
    • (2007) Cancer Research , vol.67 , Issue.8 , pp. 3853-3861
    • Kunnumakkara, A.B.1    Guha, S.2    Krishnan, S.3    Diagaradjane, P.4    Gelovani, J.5    Aggarwal, B.B.6
  • 52
    • 36849048813 scopus 로고    scopus 로고
    • Delayed activation of PKCdelta and NFkappaB and higher radioprotection in splenic lymphocytes by copper (II)-curcumin (1:1) Complex as compared to curcumin
    • DOI 10.1002/jcb.21348
    • Kunwar A, Kunwar A, Narang H et al (2007) Delayed activation of PKCdelta and NFkappaB and higher radioprotection in splenic lymphocytes by copper (II)-Curcumin (1) complex as compared to curcumin. J Cell Biochem 102(5):1214-1224 (Pubitemid 350220042)
    • (2007) Journal of Cellular Biochemistry , vol.102 , Issue.5 , pp. 1214-1224
    • Kunwar, A.1    Narang, H.2    Indira, P.K.3    Krishna, M.4    Pandey, R.5    Sainis, K.B.6
  • 53
    • 40949107359 scopus 로고    scopus 로고
    • Quantitative cellular uptake, localization and cytotoxicity of curcumin in normal and tumor cells
    • Kunwar A, Barik A, Mishra B et al (2008) Quantitative cellular uptake, localization and cytotoxicity of curcumin in normal and tumor cells. Biochim Biophys Acta 1780(4):673-679
    • (2008) Biochim Biophys Acta , vol.1780 , Issue.4 , pp. 673-679
    • Kunwar, A.1    Barik, A.2    Mishra, B.3
  • 54
    • 54949155529 scopus 로고    scopus 로고
    • Immunomodulatory effects of curcumin in allergy
    • Kurup VP, Barrios CS (2008) Immunomodulatory effects of curcumin in allergy. Mol Nutr Food Res 52(9):1031-1039
    • (2008) Mol Nutr Food Res , vol.52 , Issue.9 , pp. 1031-1039
    • Kurup, V.P.1    Barrios, C.S.2
  • 55
    • 84864408254 scopus 로고    scopus 로고
    • The tumour suppressor p53 is frequently nonfunctional in Sezary syndrome
    • Lamprecht B, Kreher S, Mobs M et al (2012) The tumour suppressor p53 is frequently nonfunctional in Sezary syndrome. Br J Dermatol 167(2):240-246
    • (2012) Br J Dermatol , vol.167 , Issue.2 , pp. 240-246
    • Lamprecht, B.1    Kreher, S.2    Mobs, M.3
  • 57
    • 33845950491 scopus 로고    scopus 로고
    • Inhibition of pancreatic and lung adenocarcinoma cell survival by curcumin is associated with increased apoptosis, down-regulation of COX-2 and EGFR and inhibition of Erk1/2 activity
    • Lev-Ari S, Starr A, Vexler A et al (2006a) Inhibition of pancreatic and lung adenocarcinoma cell survival by curcumin is associated with increased apoptosis, down-regulation of COX-2 and EGFR and inhibition of Erk1/2 activity. Anticancer Res 26(6B):4423-4430 (Pubitemid 46031517)
    • (2006) Anticancer Research , vol.26 , Issue.6 B , pp. 4423-4430
    • Lev-Ari, S.1    Starr, A.2    Vexler, A.3    Karaush, V.4    Loew, V.5    Greif, J.6    Fenig, E.7    Aderka, D.8    Ben-Yosef, R.9
  • 58
    • 31544438079 scopus 로고    scopus 로고
    • Curcumin synergistically potentiates the growth-inhibitory and pro-apoptotic effects of celecoxib in osteoarthritis synovial adherent cells
    • DOI 10.1093/rheumatology/kei132
    • Lev-Ari S, Strier L, Kazanov D et al (2006b) Curcumin synergistically potentiates the growth-inhibitory and pro-apoptotic effects of celecoxib in osteoarthritis synovial adherent cells. Rheumatology (Oxford) 45(2):171-177 (Pubitemid 43160078)
    • (2006) Rheumatology , vol.45 , Issue.2 , pp. 171-177
    • Lev-Ari, S.1    Strier, L.2    Kazanov, D.3    Elkayam, O.4    Lichtenberg, D.5    Caspi, D.6    Arber, N.7
  • 59
    • 33947270928 scopus 로고    scopus 로고
    • Curcumin, a dietary component, has anticancer, chemosensitization, and radiosensitization effects by down-regulating the MDM2 oncogene through the PI3K/mTOR/ETS2 pathway
    • DOI 10.1158/0008-5472.CAN-06-3066
    • Li M, Zhang Z, Hill DL et al (2007) Curcumin, a dietary component, has anticancer, chemosensitization, and radiosensitization effects by down-regulating the MDM2 oncogene through the PI3K/mTOR/ETS2 pathway. Cancer Res 67(5):1988-1996 (Pubitemid 46424215)
    • (2007) Cancer Research , vol.67 , Issue.5 , pp. 1988-1996
    • Li, M.1    Zhang, Z.2    Hill, D.L.3    Wang, H.4    Zhang, R.5
  • 60
    • 84859544145 scopus 로고    scopus 로고
    • Management of cutaneous T cell lymphoma: New and emerging targets and treatment options
    • Li JY, Horwitz S, Moskowitz A et al (2012) Management of cutaneous T cell lymphoma: new and emerging targets and treatment options. Cancer Manag Res 4:75-89
    • (2012) Cancer Manag Res , vol.4 , pp. 75-89
    • Li, J.Y.1    Horwitz, S.2    Moskowitz, A.3
  • 62
    • 2442521357 scopus 로고    scopus 로고
    • Curcumin and Resveratrol Induce Apoptosis and Nuclear Translocation and Activation of p53 in Human Neuroblastoma
    • Liontas A, Yeger H (2004) Curcumin and resveratrol induce apoptosis and nuclear translocation and activation of p53 in human neuroblastoma. Anticancer Res 24(2B):987-998 (Pubitemid 38625049)
    • (2004) Anticancer Research , vol.24 , Issue.2 B , pp. 987-998
    • Liontas, A.1    Yeger, H.2
  • 63
    • 34147165621 scopus 로고    scopus 로고
    • Curcumin induces heme oxygenase 1 through generation of reactive oxygen species, p38 activation and phosphatase inhibition
    • McNally SJ, Harrison EM, Ross JA et al (2007) Curcumin induces heme oxygenase 1 through generation of reactive oxygen species, p38 activation and phosphatase inhibition. Int J Mol Med 19(1):165-172
    • (2007) Int J Mol Med , vol.19 , Issue.1 , pp. 165-172
    • McNally, S.J.1    Harrison, E.M.2    Ross, J.A.3
  • 64
    • 35448932469 scopus 로고    scopus 로고
    • Curcumin prevents streptozotocin-induced islet damage by scavenging free radicals: A prophylactic and protective role
    • DOI 10.1016/j.ejphar.2007.09.002, PII S0014299907009764
    • Meghana K, Sanjeev G, Ramesh B (2007) Curcumin prevents streptozotocin-induced islet damage by scavenging free radicals: a prophylactic and protective role. Eur J Pharmacol 577(1-3):183-191 (Pubitemid 47632529)
    • (2007) European Journal of Pharmacology , vol.577 , Issue.1-3 , pp. 183-191
    • Meghana, K.1    Sanjeev, G.2    Ramesh, B.3
  • 65
    • 34047240829 scopus 로고    scopus 로고
    • Curcumin, a potential inhibitor of MMP-2 in human laryngeal squamous carcinoma cells HEp2
    • Mitra A, Chakrabarti J, Banerji A et al (2006) Curcumin, a potential inhibitor of MMP-2 in human laryngeal squamous carcinoma cells HEp2. J Environ Pathol Toxicol Oncol 25(4):679-690
    • (2006) J Environ Pathol Toxicol Oncol , vol.25 , Issue.4 , pp. 679-690
    • Mitra, A.1    Chakrabarti, J.2    Banerji, A.3
  • 66
    • 0020450453 scopus 로고
    • Anti-inflammatory and irritant activities of curcumin analogues in rats
    • DOI 10.1007/BF01965935
    • Mukhopadhyay A, Basu N, Ghatak N et al (1982) Anti-inflammatory and irritant activities of curcumin analogues in rats. Agents Actions 12(4):508-515 (Pubitemid 13218984)
    • (1982) Agents and Actions , vol.12 , Issue.4 , pp. 508-515
    • Mukhopadhyay, A.1    Basu, N.2    Ghatak, N.3    Gujral, P.K.4
  • 67
    • 70350217623 scopus 로고    scopus 로고
    • Fluorocurcumins as cyclooxygenase-2 inhibitor: Molecular docking, pharmacokinetics and tissue distribution in mice
    • Padhye S, Banerjee S, Chavan D et al (2009) Fluorocurcumins as cyclooxygenase-2 inhibitor: molecular docking, pharmacokinetics and tissue distribution in mice. Pharm Res 26(11):2438-2445
    • (2009) Pharm Res , vol.26 , Issue.11 , pp. 2438-2445
    • Padhye, S.1    Banerjee, S.2    Chavan, D.3
  • 68
    • 35148838593 scopus 로고    scopus 로고
    • Curcumin induces apoptosis and inhibits prostaglandin E(2) production in synovial fibroblasts of patients with rheumatoid arthritis
    • Park C, Moon D-O, Choi I-W et al (2007) Curcumin induces apoptosis and inhibits prostaglandin E(2) production in synovial fibroblasts of patients with rheumatoid arthritis. Int J Mol Med 20(3):365-372
    • (2007) Int J Mol Med , vol.20 , Issue.3 , pp. 365-372
    • Park, C.1    Moon, D.-O.2    Choi, I.-W.3
  • 69
    • 56349157010 scopus 로고    scopus 로고
    • Curcumin in combination with bortezomib synergistically induced apoptosis in human multiple myeloma U266 cells
    • Park J, Ayyappan V, Bae E-K et al (2008) Curcumin in combination with bortezomib synergistically induced apoptosis in human multiple myeloma U266 cells. Mol Oncol 2(4):317-326
    • (2008) Mol Oncol , vol.2 , Issue.4 , pp. 317-326
    • Park, J.1    Ayyappan, V.2    Bae, E.-K.3
  • 70
    • 36849018017 scopus 로고    scopus 로고
    • Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R
    • DOI 10.1002/ijc.23097
    • Patel BB, Sengupta R, Qazi S et al (2008) Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R. Int J Cancer 122(2):267-273 (Pubitemid 350234711)
    • (2008) International Journal of Cancer , vol.122 , Issue.2 , pp. 267-273
    • Patel, B.B.1    Sengupta, R.2    Qazi, S.3    Vachhani, H.4    Yu, Y.5    Rishi, A.K.6    Majumdar, A.P.N.7
  • 72
    • 73349094986 scopus 로고    scopus 로고
    • Curcumin and cancer cells: How many ways can curry kill tumor cells selectively?
    • Ravindran J, Prasad S, Aggarwal BB (2009) Curcumin and cancer cells: how many ways can curry kill tumor cells selectively? AAPS J 11(3):495-510
    • (2009) AAPS J , vol.11 , Issue.3 , pp. 495-510
    • Ravindran, J.1    Prasad, S.2    Aggarwal, B.B.3
  • 73
    • 0026711273 scopus 로고
    • Studies on spice principles as antioxidants in the inhibition of lipid peroxidation of rat liver microsomes
    • Reddy AC, Lokesh BR (1992) Studies on spice principles as antioxidants in the inhibition of lipid peroxidation of rat liver microsomes. Mol Cell Biochem 111(1-2):117-124
    • (1992) Mol Cell Biochem , vol.111 , Issue.1-2 , pp. 117-124
    • Reddy, A.C.1    Lokesh, B.R.2
  • 74
    • 15044362170 scopus 로고    scopus 로고
    • Design, synthesis, biological evaluation and molecular docking of curcumin analogues as antioxidant, cyclooxygenase inhibitory and anti-inflammatory agents
    • DOI 10.1016/j.bmcl.2005.02.039
    • Selvam C, Jachak SM, Thilagavathi R et al (2005) Design, synthesis, biological evaluation and molecular docking of curcumin analogues as antioxidant, cyclooxygenase inhibitory and anti-inflammatory agents. Bioorg Med Chem Lett 15(7):1793-1797 (Pubitemid 40380734)
    • (2005) Bioorganic and Medicinal Chemistry Letters , vol.15 , Issue.7 , pp. 1793-1797
    • Selvam, C.1    Jachak, S.M.2    Thilagavathi, R.3    Chakraborti, A.K.4
  • 75
    • 23044479821 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma
    • DOI 10.1016/j.bcp.2005.04.043, PII S0006295205002418
    • Shishodia S, Amin HM, Lai R et al (2005) Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma. Biochem Pharmacol 70(5):700-713 (Pubitemid 41058705)
    • (2005) Biochemical Pharmacology , vol.70 , Issue.5 , pp. 700-713
    • Shishodia, S.1    Amin, H.M.2    Lai, R.3    Aggarwal, B.B.4
  • 78
    • 84866235332 scopus 로고    scopus 로고
    • Application of UV-V is spectrophotometric and chemiluminescent methods for the evaluation of the antioxidant action of curcumin
    • Stanchev S, Pencheva I, Konstantinov S et al (2012) Application of UV-V is spectrophotometric and chemiluminescent methods for the evaluation of the antioxidant action of curcumin. J Serb Chem Soc 77(8):1063-1069
    • (2012) J Serb Chem Soc , vol.77 , Issue.8 , pp. 1063-1069
    • Stanchev, S.1    Pencheva, I.2    Konstantinov, S.3
  • 79
    • 66449104640 scopus 로고    scopus 로고
    • Curcumin circumvents chemoresistance in vitro and potentiates the effect of thalidomide and bortezomib against human multiple myeloma in nude mice model
    • Sung B, Kunnumakkara AB, Sethi G et al (2009) Curcumin circumvents chemoresistance in vitro and potentiates the effect of thalidomide and bortezomib against human multiple myeloma in nude mice model. Mol Cancer Ther 8(4):959-970
    • (2009) Mol Cancer Ther , vol.8 , Issue.4 , pp. 959-970
    • Sung, B.1    Kunnumakkara, A.B.2    Sethi, G.3
  • 81
    • 4644364745 scopus 로고    scopus 로고
    • Effect of curcumin on normal and tumor cells: Role of glutathione and bcl-2
    • Syng-Ai C, Kumari AL, Khar A (2004) Effect of curcumin on normal and tumor cells: role of glutathione and bcl-2. Mol Cancer Ther 3(9):1101-1108 (Pubitemid 39295007)
    • (2004) Molecular Cancer Therapeutics , vol.3 , Issue.9 , pp. 1101-1108
    • Syng-Ai, C.1    Kumari, A.L.2    Khar, A.3
  • 84
    • 57049125505 scopus 로고    scopus 로고
    • Curcumin attenuated the lipid peroxidation and apoptotic liver injury in copper-overloaded rats
    • Wan XH, Li YW, Luo XP (2007) Curcumin attenuated the lipid peroxidation and apoptotic liver injury in copper-overloaded rats. Zhonghua Er Ke Za Zhi 45(8):604-608
    • (2007) Zhonghua Er Ke Za Zhi , vol.45 , Issue.8 , pp. 604-608
    • Wan, X.H.1    Li, Y.W.2    Luo, X.P.3
  • 85
    • 80053571383 scopus 로고    scopus 로고
    • Evolving insights in the pathogenesis and therapy of cutaneous T-cell lymphoma (mycosis fungoides and Sezary syndrome)
    • Wong HK, Mishra A, Hake T et al (2011) Evolving insights in the pathogenesis and therapy of cutaneous T-cell lymphoma (mycosis fungoides and Sezary syndrome). Br J Haematol 155(2):150-166
    • (2011) Br J Haematol , vol.155 , Issue.2 , pp. 150-166
    • Wong, H.K.1    Mishra, A.2    Hake, T.3
  • 86
    • 79953840339 scopus 로고    scopus 로고
    • Reduction of Fas/CD95 promoter methylation, upregulation of Fas protein, and enhancement of sensitivity to apoptosis in cutaneous T-cell lymphoma
    • Wu J, Wood GS (2011) Reduction of Fas/CD95 promoter methylation, upregulation of Fas protein, and enhancement of sensitivity to apoptosis in cutaneous T-cell lymphoma. Arch Dermatol 147(4):443-449
    • (2011) Arch Dermatol , vol.147 , Issue.4 , pp. 443-449
    • Wu, J.1    Wood, G.S.2
  • 87
    • 77649283299 scopus 로고    scopus 로고
    • Reversal of multidrug resistance by curcumin through FA/BRCA pathway in multiple myeloma cell line MOLP-2/R
    • Xiao H, Xiao Q, Zhang K et al (2010) Reversal of multidrug resistance by curcumin through FA/BRCA pathway in multiple myeloma cell line MOLP-2/R. Ann Hematol 89(4):399-404
    • (2010) Ann Hematol , vol.89 , Issue.4 , pp. 399-404
    • Xiao, H.1    Xiao, Q.2    Zhang, K.3
  • 88
    • 78651102288 scopus 로고    scopus 로고
    • Erucyl-phospho-N, N, N-trimethylpropylammonium (erufosine) is a potential antimyeloma drug devoid of myelotoxicity
    • Yosifov DY, Todorov PT, Zaharieva MM et al (2011) Erucyl-phospho-N, N, N-trimethylpropylammonium (erufosine) is a potential antimyeloma drug devoid of myelotoxicity. Cancer Chemother Pharmacol 67(1):13-25
    • (2011) Cancer Chemother Pharmacol , vol.67 , Issue.1 , pp. 13-25
    • Yosifov, D.Y.1    Todorov, P.T.2    Zaharieva, M.M.3
  • 89
    • 84890551588 scopus 로고    scopus 로고
    • Alkylphosphocholines and curcumin induce programmed cell death in cutaneous T-cell lymphoma cell lines
    • Yosifov DY, Kaloyanov KA, Guenova ML et al (2014) Alkylphosphocholines and curcumin induce programmed cell death in cutaneous T-cell lymphoma cell lines. Leuk Res 38(1):49-56
    • (2014) Leuk Res , vol.38 , Issue.1 , pp. 49-56
    • Yosifov, D.Y.1    Kaloyanov, K.A.2    Guenova, M.L.3
  • 90
    • 77954762181 scopus 로고    scopus 로고
    • Curcumin selectively induces apoptosis in cutaneous T-cell lymphoma cell lines and patients' PBMCs: Potential role for STAT-3 and NF-kappaB signaling
    • Zhang C, Li B, Zhang X et al (2010) Curcumin selectively induces apoptosis in cutaneous T-cell lymphoma cell lines and patients' PBMCs: potential role for STAT-3 and NF-kappaB signaling. J Invest Dermatol 130(8):2110-2119
    • (2010) J Invest Dermatol , vol.130 , Issue.8 , pp. 2110-2119
    • Zhang, C.1    Li, B.2    Zhang, X.3
  • 91
    • 2542451035 scopus 로고    scopus 로고
    • 1-acid glycoprotein
    • DOI 10.1016/j.bmc.2004.03.074, PII S0968089604002779
    • Zsila F, Bikádi Z, SimonyiM(2004) Induced circular dichroism spectra reveal binding of the antiinflammatory curcumin to human alpha1-acid glycoprotein. Bioorg Med Chem 12(12):3239-3245 (Pubitemid 38680713)
    • (2004) Bioorganic and Medicinal Chemistry , vol.12 , Issue.12 , pp. 3239-3245
    • Zsila, F.1    Bikadi, Z.2    Simonyi, M.3


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