Design, synthesis, biological evaluation and molecular docking of curcumin analogues as antioxidant, cyclooxygenase inhibitory and anti-inflammatory agents

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 7, 2005, Pages 1793-1797

  Selvam, C ^a,b   Jachak, Sanjay M ^a   Thilagavathi, Ramasamy ^a   Chakraborti, Asit K ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

^b CNRS   (France)

Author keywords

Anti inflammatory activity; Antioxidant activity; COX 1; COX 2; Curcuminoids; Isoxazole analogues; Pyrazole analogues

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTIOXIDANT; CARRAGEENAN; CURCUMA LONGA EXTRACT; CURCUMIN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2; ISOXAZOLE; PYRAZOLE; TROLOX C;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; DRUG ACTIVITY; DRUG BINDING; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME ASSAY; NONHUMAN; PAW EDEMA; RAT;

CURCUMA LONGA;

EID: 15044362170     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.02.039     Document Type: Article

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