Immunomodulatory effects of curcumin in allergy

Molecular Nutrition and Food Research

Volumn 52, Issue 9, 2008, Pages 1031-1039

  Kurup, Viswanath P ^a   Barrios, Christy S ^a,b  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b CLEMENT J ZABLOCKI VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Allergy; Curcumin; Hypersensitivities; Immunomodulation; Turmeric

Indexed keywords

CURCUMIN; IMMUNOLOGIC FACTOR;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ALLERGY; ANIMAL; ASTHMA; DISEASE MODEL; EGYPT; HUMAN; HYPERSENSITIVITY; INDIA; PLANT ROOT; REVIEW; TRADITIONAL MEDICINE;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANIMALS; ASTHMA; CURCUMIN; DISEASE MODELS, ANIMAL; EGYPT; HUMANS; HYPERSENSITIVITY; IMMUNOLOGIC FACTORS; INDIA; LATEX HYPERSENSITIVITY; MEDICINE, TRADITIONAL; PLANT ROOTS;

ANIMALIA; CURCUMA LONGA; MURINAE;

EID: 54949155529     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.200700293     Document Type: Review

References (57)

1. Verma, V., Ayurveda: A Way of Life, Weiserbooks, Red Wheel/Weiser, Boston, MA/York Beach, ME 1995, pp. 1-277.
2. Frawley, D., Ranade, S., Ayurveda, Nature's Medicine, Motilal Banarsidass Publishers, Dehli, India 2004, pp. 1-368.
3. Bentley, R., Trimen, H., Medicinal Plants; Being Descriptions With Original Figures of the Principal Plants Employed in Medicine and an Account of the Characters, Properties, and Uses of Their Parts and Products of Medicinal Value, Churchill, London 1880.
4. National Toxicology Program. NTP Toxicology and Carcinogenesis Studies of Turmeric Oleoresin (CAS no. 8024-37-1) (Major Component 79-85% Curcumin, CAS no. 458-37-7) in F344/N Rats and B6C3F1 Mice (Feed Studies). Natl. Toxicol. Program Tech. Rep. Ser. 1993, 427, 1-275.
5. IPCS-INCHEM. Summary of evaluations performed by the joint FAO/WHO Expert Committee on Food Additives, Curcumin. Report: TRS 922-JECFA 61/18, 2003.
6. Astin, J. A., Why patients use alternative medicine: Results of a national study. JAMA 1998, 279, 1548-1553.
7. Barnes, P. M., Powell-Griner, E., McFann, K., Nahin, R. L., Complementary and alternative medicine use among adults: United States 2002. Advance Data from Vital and Health Statistics. CDC May 27, 2004, 343, 1-20.
8. Huntley, A., Ernst, E., Herbal medicines for asthma: A systematic review. Thorax 2000, 55, 925-929.
9. Kurup, V. P., Barrios, C. S., Raju, R., Johnson, B. D., et al., Immune response modulation by curcumin in a latex allergy model. Clin. Mol. Allergy 2007, 5, 1.
10. Miquel, J., Bernd, A., Sempere, J. M., Diaz-Alperi, J., Ramirez, A., The curcuma antioxidants: Pharmacological effects and prospects for future clinical use. Arch. Gerontol. Geriatr. 2002, 34, 37-46.
11. Kolev, T. M., Velcheva, E., Stamboliyska, B. A., Spiteller, M., DFTand experimental studies of the structure and vibrational spectra of curcumin. Int. J. Quantum. Chem. 2004, 102, 1069.
12. Aggarwal, B. B., Kumar, A., Bharti, A. C., Anticancer potential of curcumin: Preclinical and clinical studies. Anticancer Res. 2003, 23, 363-398.
13. Toda, S., Miyase, T., Arichi, H., Tanizawa, H., Takino, Y., Natural antioxidants. III. Antioxidative components isolated from rhizome of Curcuma longa. Chem. Pharm. Bull. 1985, 33, 1725-1728.
14. Padmaja, S., Raju, T. N., Antioxidant effect of curcumin in selenium induced cataract of Wistar rats. Indian J. Exp. Biol. 2004, 42, 601-603.
15. Dikshit, M., Rastogi, L., Shukla, R., Srimal, R. C., Prevention of ischaemia-induced biochemical changes by curcumin and quinidine in the cat heart. Indian J. Med. Res. 1995, 101, 31-35.
16. Mortellini, R., Foresti, R., Bassi, R., Green, C. J., Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress. Free Radic. Biol. Med. 2000, 28, 1303-1312.
17. Brouet, I., Ohshima, H., Curcumin, an anti-tumour promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthetase in activated macrophages. Biochem. Biophys. Res. Commun. 1995, 206, 533-540.
18. Mukhopadhyay, A., Basu, N., Ghatak, N., Gujral, P. K., Antiinflammatory and irritant activities of curcumin analogues in rats. Agents Actions 1982, 12, 508-515.
19. Srivastava, R., Inhibition of neutrophil response by curcumin. Agents Actions 1989, 28, 298-303.
20. Chandra, D., Gupta, S., Anti-inflammatory and anti-arthritic activity of volatile oil of Curcuma longa (Haldi). Ind. J. Med. Res. 1972, 60, 138-142.
21. Arora, R. B., Kapoor, V., Basu, N., Jain, A. P., Anti-inflammatory studies on Curcuma longa (turmeric). Ind. J. Med. Res. 1971, 59, 1289-1295.
22. Kato, K., Ito, H., Kamei, K., Iwamoto, I., Stimulation of the stress-induced expression of stress proteins by curcumin in cultured cells and in rat tissues in vivo. Cell Stress Chaperones 1998, 3, 152-160.
23. Kawamori, T., Lubet, R., Steele, V. E., Kelloff, G. J., et al., Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer. Cancer Res. 1999, 59, 597-601.
24. Thaloor, D., Singh, A. K., Sidhu, G. S., Prasad, P. V., et al., Inhibition of angiogenic differentiation of human umbilical vein endothelial cells by curcumin. Cell Growth Differ. 1998, 9, 305-312.
25. Arbiser, J. L., Klauber, N., Rohan, R., van Leeuwen, R., et al., Curcumin is an in vivo inhibitor of angiogenesis. Mol. Med. 1998, 4, 376-383.
26. Limtrakul, P., Lipigorngoson, S., Namwong, O., Apisariyakul, A., Dunn, F. W., Inhibitory effect of dietary curcumin on skin carcinogenesis in mice. Cancer Lett. 1997, 116, 197-203.
27. Hanif, R., Qiao, L., Shift, S. J., Rigas, B., Curcumin, a natural plant phenolic food additive, inhibits cell proliferation and induces cell cycle changes in colon adenocarcinoma cell lines by a prostaglandin-independent pathway. J. Lab. Clin. Med. 1997, 130, 576-584.
28. Dorai, T., Cao, Y. C., Dorai, B., Buttyan, R., Katz, A. E., Therapeutic potential of curcumin in human prostate cancer. III. Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo. Prostate 2001, 47, 293-303.
29. Mehta, R. G., Moon, R. C., Characterization of effective chemopreventive agents in mammary gland in vitro using and initiation-promotion protocol. Anticancer Res. 1991, 11, 593-596.
30. Soudamini, N. K., Kuttan, R., Inhibition of chemical carcinogenesis by curcumin. J. Ethnopharmacol. 1989, 27, 227-233.
31. Azuine, M., Bhide, S., Chemopreventive effect of turmeric against stomach and skin tumors induced by chemical carcinogens in Swiss mice. Nutr. Cancer. 1992, 17, 77-83.
32. Boone, C. W., Steele, V. E., Kelloff, G. J., Screening of chemopreventive (anticarcinogenic) compounds in rodents. Mut. Res. 1992, 267, 251-255.
33. Siwak, D. R., Shishodia, S., Aggarwal, B. B., Kurzrock, R., Curcumin-induced antiproliferative and proapoptotic effects in melanoma cells are associated with suppression of IkappaB kinase and nuclear factor kappaB activity and are independent of the B-Raf/mitogen-activated/extracellular signalregulated protein kinase pathway and the Akt pathway. Cancer. 2005, 104, 879-890.
34. Hahm, E. R., Cheon, G., Lee, J. H., Kim, B. J., et al., New and known symmetrical curcumin derivatives inhibit the formation of Fos-Jun-DNA complex. Cancer Lett. 2002, 184, 89-96.
35. Han, S. S., Keum, Y. S., Soe, H. J., Surh, Y. J., Curcumin suppresses activation of NF-κB and AP-1 induced by phorbol ester in cultured human promyeelocytic leukemia cells. J. Biochem. Mol. Biol. 2002, 35, 337-342.
36. Cheng, A. L., Hsu, C. H., Lin, J. K., Hsu, M. M., et al., Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or premalignant lesions. Anticancer Res. 2001, 21, 2895-2900.
37. Sharma, R. A., Gescher, A. J., Steward, W. P., Curcumin: The story so far. Eur. J. Cancer. 2005, 41, 1955-1968.
38. Manikandan, P., Sumitra, M., Aishwarya, S., Manohar, B. M., et al., Curcumin modulates free radical quenching in myocardial ischaemia in rats. Int. J. Biochem. Cell Biol. 2004, 36, 1967-1980.
39. Ramirez-Tortosa, M. C., Mesa, M. D., Aguilera, M. C., Quiles, J. L., et al., Oral administration of a turmeric extract inhibits LDL oxidation and has hypocholeterolemic effects in rabbits with experimental atherosclerosis. Atherosclerosis 1999, 147, 371-378.
40. Holt, P. R., Katz, S., Kirshoff, R., Curcumin therapy in inflammatory bowel disease: A pilot study. Dig. Dis. Sci. 2005, 50, 2191-2193.
41. Mahady, G. B., Pendland, S. L., Yun, G., Lu, Z. Z., Turmeric (Curcuma longa) and curcumin inhibit the growth of Helicobacter pylori, a group 1 carcinogen. Anticancer Res. 2002, 22, 4179-4181.
42. Ammon, H. P. T., Wahl, M. A., Pharmacology of Curcuma longa. Planta Medica 1991, 57, 1-7.
43. Rafatullah, S., Tariq, M., Al-Yahya, M. A., Mossa, J. S., Ageel, A. M., Evaluation of turmeric (Curcuma longa) for gastric and duodenal antiulcer activity in rats. J. Ethnopharmacol. 1990, 29, 25-34.
44. Barthelemy, S., Vergnes, L., Moynier, M., Guyot, D., et al., Curcumin and curcumin derivative inhibit Tat-mediated transactivation of type 1 human immunodeficiency virus long terminal repeat. Res. Virol. 1998, 149, 43-52.
45. Copeland, R., Baker, D., Wilson, H., Curcumin therapy in HIV-infected patients initially increased CD-4 and CD-8 cell counts. Int. Conf. AIDS (abstract no. PB0876) 1994, 10, 216.
46. Liu, J. P., Manheimer, E., Yang, M., Herbal medicines for treating HIV infection and AIDS. Cochrane Database Syst. Rev. 2005, 3, CD003937.
47. Ono, K., Hasegaw, K., Naiki, H., Yamada, M., Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro. J. Neurosci. Res. 2004, 75, 742-750.
48. Garcia-Alloza, M., Borrelli, L. A., Rozkalne, A., Hyman, B.T., Bacskai B.J., Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model. J. Neurochem. 2007, 102, 1095-1104.
49. Gao, X., Kuo, J., Jiang, H., Deeb, D., et al., Immunomodulatory activity of curcumin: suppression of lymphocyte proliferation, development of cell-mediated cytotoxicity, and cytokine production in vitro. Biochem. Pharmacol. 2004, 68, 51-61.
50. Yadav, V. S., Mishra, K. P., Singh, D. P., Mehrotra, S., Singh, V. K., Immunomodulatory effects of curcumin. Immunopharmacol. Immunotoxicol. 2005, 27, 485-497.
51. Kang, B. Y., Song, Y. J., Kim, K. M., Choe, Y. K., et al., Curcumin inhibits Th1 cytokine profile in CD4+ T cells by suppressing interleukin-12 production in macrophages. Br. J. Pharmacol. 1999, 128, 380-384.
52. Jagetia, G. C., Aggarwal, B. B., "Spicing up" of the immune system by curcumin. J. Clin. Immunol. 2007, 27, 19-35.
53. Yano, S., Terai, M., Shimizu, K. L., Horie, S., Futagami, Y., Antiallergic Activity of Curcuma longa. (I). Effectiveness of Extracts Containing Curcuminoids. Nat. Med. 2000, 54, 318-324.
54. Yano, S., Terai, M., Shimizu, K. L., Futagami, Y., et al., Antiallergic Activity of Curcuma longa. (II). Features of inhibitory actions on histamine release from mast cells. Nat. Med. 2000, 54, 325-329.
55. Ram, A., Das, M., Ghosh, B., Curcumin Attenuates Allergen-Induced Airway Hyperresponsiveness in Sensitized Guinea Pigs. Biol. Pharm. Bull. 2003, 26, 1021-1024.
56. Suzuki, M., Nakamura, T., Iyoki, S., Fujiwara, A., et al., Elucidation of anti-allergic activities of curcumin-related compounds with a special reference to their anti-oxidative activities. Biol. Pharm. Bull. 2005, 28, 1438-1443.
57. Kurup, V., Barrios, C., Johnson, B., Fink, J., Intragastric curcumin downregulates Aspergillus antigen induced Th2 response in a murine model of allergic aspergillosis. J. Allergy Clin. Immunol. 2006, 117, S203-S203.