The cardiac ryanodine receptor luminal Ca2+ sensor governs Ca2+ waves, ventricular tachyarrhythmias and cardiac hypertrophy in calsequestrin-null mice

Biochemical Journal

Volumn 461, Issue 1, 2014, Pages 99-106

  Zhang, Jingqun ^a,d   Chen, Biyi ^b   Zhong, Xiaowei ^c   Mi, Tao ^c,d   Guo, Ang ^b   Zhou, Qiang ^a,d   Tan, Zhen ^a   Wu, Guogen ^a   Chen, Alexander W ^c   Fill, Michael ^a   Song, Long Sheng ^b   Chen, S R Wayne ^a,c  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c UNIVERSITY OF CALGARY   (Canada)

^d HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Calsequestrin; Cardiomyopathy; Ryanodine receptor; Sarcoplasmic reticulum

Indexed keywords

CALCIUM ION; CALSEQUESTRIN; GLUTAMIC ACID; GLUTAMINE; RYANODINE RECEPTOR 2;

ADRENERGIC STIMULATION; AMINO ACID SUBSTITUTION; AMPLITUDE MODULATION; ANIMAL EXPERIMENT; ARTICLE; CALCIUM SIGNALING; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ELECTRIC POTENTIAL; GENE MUTATION; HEART MUSCLE; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE TACHYCARDIA; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SARCOPLASMIC RETICULUM; SENSOR; SPONTANEOUS CALCIUM WAVE; STRESS;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CALSEQUESTRIN; CARDIOMEGALY; MICE; MICE, KNOCKOUT; MUTATION; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; TACHYCARDIA, VENTRICULAR;

EID: 84902318460     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20140126     Document Type: Article

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