Heterogeneity of ryanodine receptor dysfunction in a mouse model of catecholaminergic polymorphic ventricular tachycardia

Circulation Research

Volumn 112, Issue 2, 2013, Pages 298-308

  Loaiza, Randall ^a   Benkusky, Nancy A ^b   Powers, Patricia P ^d   Hacker, Timothy ^c   Noujaim, Sami ^a   Ackerman, Michael J ^e,f   Jalife, José ^a   Valdivia, Héctor H ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b Department of Biochemistry ^*  (United States)

^c Internal Medicine   (United States)

^d Biotechnology Center   (United States)

^e UNIVERSITY OF WISCONSIN MADISON   (United States)

^f MAYO CLINIC   (United States)

Author keywords

atecholaminergic polymorphic ventricular tachycardia; inherited arrhythmias; ryanodine receptor

Indexed keywords

ADRENALIN; ATM PROTEIN; CAFFEINE; CALCIUM; CALCIUM CHANNEL; ISOPRENALINE; PROTEIN KINASE; RYANODINE RECEPTOR 2;

ADRENERGIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BETA ADRENERGIC STIMULATION; CALCIUM TRANSPORT; CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOSOL; ENZYME PHOSPHORYLATION; GENE MUTATION; GENE SILENCING; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; HEART ARRHYTHMIA; HEART STRESS; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; LATENT PERIOD; MOUSE; MUSCLE CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING;

ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; GENE KNOCK-IN TECHNIQUES; GENETIC HETEROGENEITY; HEK293 CELLS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; TACHYCARDIA, VENTRICULAR;

EID: 84872851693     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.112.274803     Document Type: Article

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