In situ confocal imaging in intact heart reveals stress-induced ca2+ release variability in a murine catecholaminergic polymorphic ventricular tachycardia model of type 2 ryanodine receptorr4496c+/? mutation

Circulation: Arrhythmia and Electrophysiology

Volumn 5, Issue 4, 2012, Pages 841-849

  Chen, Biyi ^a   Guo, Ang ^a   Gao, Zhan ^a   Wei, Sheng ^b   Xie, Yu Ping ^a   Chen, S R Wayne ^c   Anderson, Mark E ^a   Song, Long Sheng ^a  

^a UNIVERSITY OF IOWA   (United States)

^b PEKING UNIVERSITY   (China)

^c UNIVERSITY OF CALGARY   (Canada)

Author keywords

Arrhythmia (mechanisms); Calcium; Catecholaminergic polymorphic ventricular tachycardia; Ryanodine receptors; Sarcoplasmic reticulum

Indexed keywords

CALCIUM CHANNEL; RYANODINE RECEPTOR;

ADRENERGIC STIMULATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA; CELL CYCLE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; EXCITATION CONTRACTION COUPLING; GENE MUTATION; ISOLATED HEART; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ACTION POTENTIALS; ADRENERGIC AGONISTS; ANIMALS; CALCIUM SIGNALING; DISEASE MODELS, ANIMAL; ELECTROCARDIOGRAPHY; EPINEPHRINE; EXCITATION CONTRACTION COUPLING; GENETIC PREDISPOSITION TO DISEASE; KINETICS; MICE; MICE, MUTANT STRAINS; MICROSCOPY, CONFOCAL; MUTATION; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PERFUSION; PHENOTYPE; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; TACHYCARDIA, VENTRICULAR;

EID: 84867183079     PISSN: 19413149     EISSN: 19413084     Source Type: Journal    
DOI: 10.1161/CIRCEP.111.969733     Document Type: Article

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