Luminal Ca2+ regulation of single cardiac ryanodine receptors: Insights provided by calsequestrin and its mutants

Journal of General Physiology

Volumn 131, Issue 4, 2008, Pages 325-334

  Qin, Jia ^a   Valle, Giorgia ^b   Nani, Alma ^a   Nori, Alessandra ^b   Rizzi, Nicoletta ^c   Priori, Silvia G ^c   Volpe, Pompeo ^b   Fill, Michael ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF PADOVA   (Italy)

^c UNIVERSITY OF PAVIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CALCIUM ION; CALSEQUESTRIN; GLUTAMINE; HISTIDINE; LEUCINE; MAGNESIUM ION; MEMBRANE PROTEIN; MONOMER; MUTANT PROTEIN; OLIGOMER; RYANODINE RECEPTOR 2; TRIADIN; UNCLASSIFIED DRUG; CALCIUM; MAGNESIUM; RYANODINE RECEPTOR;

ARTICLE; BINDING AFFINITY; CALCIUM BINDING; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA; CYTOSOL; OLIGOMERIZATION; PHENOTYPE; PROTEIN FUNCTION; AMINO ACID SUBSTITUTION; ANIMAL; CALCIUM SIGNALING; CHANNEL GATING; CHEMISTRY; DIMERIZATION; ELECTRIC CONDUCTIVITY; HEART MUSCLE CELL; HEART VENTRICLE TACHYCARDIA; LIPID BILAYER; METABOLISM; MICROSOME; PATCH CLAMP; PATHOPHYSIOLOGY; PHYSIOLOGY; RAT; SARCOPLASMIC RETICULUM; STRUCTURE ACTIVITY RELATION;

AMINO ACID SUBSTITUTION; ANIMALS; CALCIUM; CALCIUM SIGNALING; CALSEQUESTRIN; CYTOSOL; DIMERIZATION; ELECTRIC CONDUCTIVITY; ION CHANNEL GATING; LIPID BILAYERS; MAGNESIUM; MICROSOMES; MUTANT PROTEINS; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; RATS; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; STRUCTURE-ACTIVITY RELATIONSHIP; TACHYCARDIA, VENTRICULAR;

EID: 41649087866     PISSN: 00221295     EISSN: 00221295     Source Type: Journal    
DOI: 10.1085/jgp.200709907     Document Type: Article

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