Persistent activation of DNA damage signaling in response to complex mixtures of PAHs in air particulate matter

Toxicology and Applied Pharmacology

Volumn 266, Issue 3, 2013, Pages 408-418

  Jarvis, Ian W H ^a   Bergvall, Christoffer ^b   Bottai, Matteo ^a   Westerholm, Roger ^b   Stenius, Ulla ^a   Dreij, Kristian ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

Air particulate matter; Benzo a pyrene; Complex mixtures; Dibenzo a,l pyrene; PAHs; Risk assessment

Indexed keywords

BENZO[A]PYRENE; CHECKPOINT KINASE 1; DIBENZO[A,L]PYRENE; DNA; POLYCYCLIC AROMATIC HYDROCARBON;

AIR SAMPLING; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA DAMAGE; FRACTIONATION; HUMAN; HUMAN CELL; PARTICULATE MATTER; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STATISTICAL MODEL; URBAN AREA;

ARYL HYDROCARBON HYDROXYLASES; BENZO(A)PYRENE; BENZOPYRENES; BLOTTING, WESTERN; CELL SURVIVAL; COMET ASSAY; CYTOCHROME P-450 CYP1A1; DNA DAMAGE; HEP G2 CELLS; HUMANS; LINEAR MODELS; LIVER; PARTICULATE MATTER; PROTEIN KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SIGNAL TRANSDUCTION; URBAN POPULATION;

EID: 84871906235     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.11.026     Document Type: Article

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