Constitutive activity in the angiotensin II type 1 receptor: Discovery and applications

Advances in Pharmacology

Volumn 70, Issue , 2014, Pages 155-174

  Unal, Hamiyet ^a   Karnik, Sadashiva S ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Angiotensin II; AT1 receptor; Constitutive activity; GPCR; Inverse agonist

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; AUTOANTIBODY; GLYCINE; GUANINE NUCLEOTIDE BINDING PROTEIN; MUTANT PROTEIN; PARTIAL AGONIST; RENIN; SERINE;

AMINO ACID SUBSTITUTION; ARTICLE; CELL MEMBRANE; GENE MUTATION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HUMAN; HYPERTENSION; INVERSE AGONISM; MECHANICAL STRESS; MOLECULAR INTERACTION; MOLECULAR MECHANICS; MOLECULAR MODEL; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; SYMPATHETIC TONE; TRANSGENIC ANIMAL; VASCULAR ENDOTHELIUM; AGONISTS; ANIMAL; CHEMISTRY; DRUG DEVELOPMENT; GENETICS; MEDICAL RESEARCH; METABOLISM; MUTATION;

ANIMALS; BIOMEDICAL RESEARCH; DRUG DISCOVERY; DRUG INVERSE AGONISM; HUMANS; MUTATION; RECEPTOR, ANGIOTENSIN, TYPE 1;

EID: 84902210472     PISSN: 10543589     EISSN: 15578925     Source Type: Book Series    
DOI: 10.1016/B978-0-12-417197-8.00006-7     Document Type: Chapter

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