Ursolic acid ameliorates carbon tetrachloride-induced oxidative DNA damage and inflammation in mouse kidney by inhibiting the STAT3 and NF-κB activities

International Immunopharmacology

Volumn 21, Issue 2, 2014, Pages 389-395

  Ma, Jie Qiong ^a   Ding, Jie ^a   Xiao, Zheng Hua ^a   Liu, Chan Min ^b  

^a SICHUAN UNIVERSITY OF SCIENCE AND ENGINEERING   (China)

^b JIANGSU NORMAL UNIVERSITY   (China)

Author keywords

Kidney inflammation; NF B; Oxidative stress; STAT3; Ursolic acid

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; CARBON TETRACHLORIDE; CREATININE; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 17; INTERLEUKIN 6; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TUMOR NECROSIS FACTOR ALPHA; UREA; URIC ACID; URSOLIC ACID; ANTIOXIDANT; STAT3 PROTEIN, MOUSE; TRITERPENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CYTOKINE PRODUCTION; DNA DAMAGE; DOSE RESPONSE; DRUG MEGADOSE; HISTOPATHOLOGY; KIDNEY DYSFUNCTION; KIDNEY INJURY; KIDNEY TUBULE ABSORPTION; LIPID PEROXIDATION; LOW DRUG DOSE; MALE; MOUSE; NEPHRITIS; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RENAL PROTECTION; SIGNAL TRANSDUCTION; TREATMENT DURATION; UREA BLOOD LEVEL; URIC ACID BLOOD LEVEL; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; DRUG EFFECTS; INFLAMMATION; INSTITUTE FOR CANCER RESEARCH MOUSE; KIDNEY; METABOLISM; PHOSPHORYLATION; RENAL INSUFFICIENCY;

ANIMALS; ANTIOXIDANTS; CARBON TETRACHLORIDE; CYCLOOXYGENASE 2; DNA DAMAGE; INFLAMMATION; INTERLEUKIN-17; INTERLEUKIN-6; KIDNEY; LIPID PEROXIDATION; MALE; MICE; MICE, INBRED ICR; NF-KAPPA B; OXIDATIVE STRESS; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; RENAL INSUFFICIENCY; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRITERPENES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84902201385     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.05.022     Document Type: Article

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