Genetic disruption of the murine complement C3 promoter region generates deficient mice with extrahepatic expression of C3 mRNA

Immunopharmacology

Volumn 42, Issue 1-3, 1999, Pages 135-149

  Circolo, Antonella ^a   Garnier, Gérard ^a   Fukuda, Wataru ^a   Wang, Xeufeng ^a   Hidvegi, Tünde ^a   Szalai, Alexander J ^a   Briles, David E ^a   Volanakis, John E ^a   Wetsel, Rick A ^a   Colten, Harvey R ^a  

^a NONE

Author keywords

C3 deficient mice; Complement C3; Gene targeting; Tissue specific expression

Indexed keywords

COMPLEMENT COMPONENT C3; MESSENGER RNA;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; BACTEREMIA; COMPLEMENT DEFICIENCY; CONFERENCE PAPER; CONTROLLED STUDY; DNA FLANKING REGION; EMBRYO; GENE DELETION; HEART; IMMUNE RESPONSE; KIDNEY; LIVER; LUNG; MALE; METABOLISM; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROCESSING; PROTEIN SECRETION; RNA TRANSLATION; SPLEEN; STREPTOCOCCUS PNEUMONIAE; TRANSCRIPTION INITIATION;

ANIMALS; BASE SEQUENCE; BLOTTING, NORTHERN; CHLORAMPHENICOL O-ACETYLTRANSFERASE; COMPLEMENT C3; DNA; EXONS; FEMALE; GENE DELETION; GENE EXPRESSION; GENE TARGETING; IMMUNITY, NATURAL; IN SITU HYBRIDIZATION; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; PNEUMOCOCCAL INFECTIONS; PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; STREPTOCOCCUS PNEUMONIAE;

EID: 0033062148     PISSN: 01623109     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0162-3109(99)00021-1     Document Type: Conference Paper

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