-
1
-
-
0036482917
-
Successful antiangiogenic therapy of giant cell angioblastoma with interferon alfa 2b: Report of 2 cases
-
Marler JJ, et al. Successful antiangiogenic therapy of giant cell angioblastoma with interferon alfa 2b: report of 2 cases. Pediatrics. 2002;109(2):E37.
-
(2002)
Pediatrics.
, vol.109
, Issue.2
-
-
Marler, J.J.1
-
2
-
-
0020041976
-
Hemangiomas and vascular malformations in infants and children: A classification based on endothelial characteristics
-
Mulliken JB, Glowacki J. Hemangiomas and vascular malformations in infants and children: a classification based on endothelial characteristics. Plast Reconstr Surg. 1982;69(3):412-422.
-
(1982)
Plast Reconstr Surg.
, vol.69
, Issue.3
, pp. 412-422
-
-
Mulliken, J.B.1
Glowacki, J.2
-
4
-
-
78649263829
-
Vascular anomalies: Current overview of the field
-
Greene AK. Vascular anomalies: current overview of the field. Clin Plast Surg. 2011;38(1):1-5.
-
(2011)
Clin Plast Surg.
, vol.38
, Issue.1
, pp. 1-5
-
-
Greene, A.K.1
-
5
-
-
0347362524
-
Capillary malformation-arteriovenous malformation, a new clinical and genetic disorder caused by RASA1 mutations
-
Eerola I, et al. Capillary malformation-arteriovenous malformation, a new clinical and genetic disorder caused by RASA1 mutations. Am J Hum Genet. 2003;73(6):1240-1249.
-
(2003)
Am J Hum Genet.
, vol.73
, Issue.6
, pp. 1240-1249
-
-
Eerola, I.1
-
6
-
-
19444387096
-
RASA1: Variable phenotype with capillary and arteriovenous malformations
-
Boon LM, Mulliken JB, Vikkula M. RASA1: variable phenotype with capillary and arteriovenous malformations. Curr Opin Genet Dev. 2005;15(3):265-269.
-
(2005)
Curr Opin Genet Dev.
, vol.15
, Issue.3
, pp. 265-269
-
-
Boon, L.M.1
Mulliken, J.B.2
Vikkula, M.3
-
7
-
-
46749101035
-
Parkes Weber syndrome, vein of Galen aneurysmal malformation, and other fastflow vascular anomalies are caused by RASA1 mutations
-
Revencu N, et al. Parkes Weber syndrome, vein of Galen aneurysmal malformation, and other fastflow vascular anomalies are caused by RASA1 mutations. Hum Mutat. 2008;29(7):959-965.
-
(2008)
Hum Mutat.
, vol.29
, Issue.7
, pp. 959-965
-
-
Revencu, N.1
-
8
-
-
84858866422
-
Phenotypic variability in a family with capillary malformations caused by a mutation in the RASA1 gene
-
de Wijn RS, Oduber CE, Breugem CC, Alders M, Hennekam RC, van der Horst CM. Phenotypic variability in a family with capillary malformations caused by a mutation in the RASA1 gene. Eur J Med Genet. 2012;55(3):191-195.
-
(2012)
Eur J Med Genet.
, vol.55
, Issue.3
, pp. 191-195
-
-
De Wijn, R.S.1
Oduber, C.E.2
Breugem, C.C.3
Alders, M.4
Hennekam, R.C.5
Van Der Horst, C.M.6
-
9
-
-
84887617105
-
RASA1 Mutations and Associated Phenotypes in 68 Families with Capillary Malformation-Arteriovenous Malformation
-
Revencu N, et al. RASA1 Mutations and Associated Phenotypes in 68 Families with Capillary Malformation-Arteriovenous Malformation. Hum Mutat. 2013;34(12):1632-1641.
-
(2013)
Hum Mutat.
, vol.34
, Issue.12
, pp. 1632-1641
-
-
Revencu, N.1
-
10
-
-
77951056493
-
Extracranial arteriovenous malformations: Natural progression and recurrence after treatment
-
Liu AS, Mulliken JB, Zurakowski D, Fishman SJ, Greene AK. Extracranial arteriovenous malformations: natural progression and recurrence after treatment. Plast Reconstr Surg. 2010;125(4):1185-1194.
-
(2010)
Plast Reconstr Surg.
, vol.125
, Issue.4
, pp. 1185-1194
-
-
Liu, A.S.1
Mulliken, J.B.2
Zurakowski, D.3
Fishman, S.J.4
Greene, A.K.5
-
11
-
-
0028788570
-
Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein
-
Henkemeyer M, et al. Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein. Nature. 1995;377(6551):695-701.
-
(1995)
Nature
, vol.377
, Issue.6551
, pp. 695-701
-
-
Henkemeyer, M.1
-
12
-
-
84866158884
-
Genetic causes of vascular malformations
-
Brouillard P, Vikkula M. Genetic causes of vascular malformations. Hum Mol Genet. 2007;16(spec no. 2):R140-R149.
-
(2007)
Hum Mol Genet.
, vol.16
, Issue.2
-
-
Brouillard, P.1
Vikkula, M.2
-
13
-
-
0037451803
-
GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila
-
Bernards A. GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila. Biochim Biophys Acta. 2003;1603(2):47-82.
-
(2003)
Biochim Biophys Acta.
, vol.1603
, Issue.2
, pp. 47-82
-
-
Bernards, A.1
-
14
-
-
0037264633
-
Targeting RAS signalling pathways in cancer therapy
-
Downward J. Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer. 2003;3(1):11-22.
-
(2003)
Nat Rev Cancer
, vol.3
, Issue.1
, pp. 11-22
-
-
Downward, J.1
-
15
-
-
0027454104
-
Nonsense mutations in the C-terminal SH2 region of the GTPase activating protein (GAP) gene in human tumours
-
Friedman E, Gejman PV, Martin GA, McCormick F. Nonsense mutations in the C-terminal SH2 region of the GTPase activating protein (GAP) gene in human tumours. Nat Genet. 1993;5(3):242-247.
-
(1993)
Nat Genet.
, vol.5
, Issue.3
, pp. 242-247
-
-
Friedman, E.1
Gejman, P.V.2
Martin, G.A.3
McCormick, F.4
-
16
-
-
0027976709
-
Genetic analysis of the catalytic domain of the GAP gene in human lung cancer cell lines
-
Mitsudomi T, Friedman E, Gejman PV, McCormick F, Gazdar AF. Genetic analysis of the catalytic domain of the GAP gene in human lung cancer cell lines. Hum Genet. 1994;93(1):27-31.
-
(1994)
Hum Genet.
, vol.93
, Issue.1
, pp. 27-31
-
-
Mitsudomi, T.1
Friedman, E.2
Gejman, P.V.3
McCormick, F.4
Gazdar, A.F.5
-
17
-
-
84856540111
-
RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice
-
Lapinski PE, et al. RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice. J Clin Invest. 2012;122(2):733-747.
-
(2012)
J Clin Invest.
, vol.122
, Issue.2
, pp. 733-747
-
-
Lapinski, P.E.1
-
18
-
-
0025630506
-
The tyrosine phosphorylated carboxyterminus of the EGF receptor is a binding site for GAP and PLC-γ
-
Margolis B, et al. The tyrosine phosphorylated carboxyterminus of the EGF receptor is a binding site for GAP and PLC-γ. EMBO J. 1990;9(13):4375-4380.
-
(1990)
EMBO J.
, vol.9
, Issue.13
, pp. 4375-4380
-
-
Margolis, B.1
-
19
-
-
0025252220
-
PDGF β-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex
-
Kaplan DR, Morrison DK, Wong G, McCormick F, Williams LT. PDGF β-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex. Cell. 1990;61(1):125-133.
-
(1990)
Cell
, vol.61
, Issue.1
, pp. 125-133
-
-
Kaplan, D.R.1
Morrison, D.K.2
Wong, G.3
McCormick, F.4
Williams, L.T.5
-
20
-
-
0031001812
-
Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells
-
Holland SJ, et al. Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells. EMBO J. 1997;16(13):3877-3888.
-
(1997)
EMBO J.
, vol.16
, Issue.13
, pp. 3877-3888
-
-
Holland, S.J.1
-
21
-
-
0033082959
-
Roles of ephrinB ligands and EphB receptors in cardiovascular development: Demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis
-
Adams RH, et al. Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis. Genes Dev. 1999;13(3):295-306.
-
(1999)
Genes Dev.
, vol.13
, Issue.3
, pp. 295-306
-
-
Adams, R.H.1
-
22
-
-
0033197535
-
Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development
-
Gerety SS, Wang HU, Chen ZF, Anderson DJ. Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development. Mol Cell. 1999;4(3):403-414.
-
(1999)
Mol Cell
, vol.4
, Issue.3
, pp. 403-414
-
-
Gerety, S.S.1
Wang, H.U.2
Chen, Z.F.3
Anderson, D.J.4
-
23
-
-
0032577446
-
Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4
-
Wang HU, Chen ZF, Anderson DJ. Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell. 1998;93(5):741-753.
-
(1998)
Cell
, vol.93
, Issue.5
, pp. 741-753
-
-
Wang, H.U.1
Chen, Z.F.2
Anderson, D.J.3
-
24
-
-
63649138023
-
Arterial-venous specification during development
-
Swift MR, Weinstein BM. Arterial-venous specification during development. Circ Res. 2009;104(5):576-588.
-
(2009)
Circ Res.
, vol.104
, Issue.5
, pp. 576-588
-
-
Swift, M.R.1
Weinstein, B.M.2
-
25
-
-
3042680296
-
Ephrin-B2 reverse signaling is required for axon pathfinding and cardiac valve formation but not early vascular development
-
Cowan CA, et al. Ephrin-B2 reverse signaling is required for axon pathfinding and cardiac valve formation but not early vascular development. Dev Biol. 2004;271(2):263-271.
-
(2004)
Dev Biol.
, vol.271
, Issue.2
, pp. 263-271
-
-
Cowan, C.A.1
-
26
-
-
13244292521
-
PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature
-
Makinen T, et al. PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature. Genes Dev. 2005;19(3):397-410.
-
(2005)
Genes Dev.
, vol.19
, Issue.3
, pp. 397-410
-
-
Makinen, T.1
-
27
-
-
30344440869
-
Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly
-
Foo SS, et al. Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly. Cell. 2006;124(1):161-173.
-
(2006)
Cell
, vol.124
, Issue.1
, pp. 161-173
-
-
Foo, S.S.1
-
28
-
-
77955384669
-
MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis
-
Anand S, et al. MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis. Nat Med. 2010;16(8):909-914.
-
(2010)
Nat Med.
, vol.16
, Issue.8
, pp. 909-914
-
-
Anand, S.1
-
29
-
-
0029778783
-
Disruption of hemoglobin oxygen transport does not impact oxygendependent physiological processes in developing embryos of zebra fish (Danio rerio)
-
Pelster B, Burggren WW. Disruption of hemoglobin oxygen transport does not impact oxygendependent physiological processes in developing embryos of zebra fish (Danio rerio). Circ Res. 1996;79(2):358-362.
-
(1996)
Circ Res.
, vol.79
, Issue.2
, pp. 358-362
-
-
Pelster, B.1
Burggren, W.W.2
-
30
-
-
0033072317
-
O2 consumption and heart rate in developing zebrafish (Danio rerio): Influence of temperature and ambient O2
-
Barrionuevo WR, Burggren WW. O2 consumption and heart rate in developing zebrafish (Danio rerio): influence of temperature and ambient O2. Am J Physiol. 1999;276(2 pt 2):R505-R513.
-
(1999)
Am J Physiol.
, vol.276
, Issue.2 PART 2
-
-
Barrionuevo, W.R.1
Burggren, W.W.2
-
31
-
-
33749208029
-
Morphants: A new systematic vertebrate functional genomics approach
-
Ekker SC. Morphants: a new systematic vertebrate functional genomics approach. Yeast. 2000;17(4):302-306.
-
(2000)
Yeast.
, vol.17
, Issue.4
, pp. 302-306
-
-
Ekker, S.C.1
-
32
-
-
0036039827
-
In vivo imaging of embryonic vascular development using transgenic zebrafish
-
Lawson ND, Weinstein BM. In vivo imaging of embryonic vascular development using transgenic zebrafish. Dev Biol. 2002;248(2):307-318.
-
(2002)
Dev Biol.
, vol.248
, Issue.2
, pp. 307-318
-
-
Lawson, N.D.1
Weinstein, B.M.2
-
33
-
-
0347382591
-
Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants
-
Traver D, Paw BH, Poss KD, Penberthy WT, Lin S, Zon LI. Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nat Immunol. 2003;4(12):1238-1246.
-
(2003)
Nat Immunol.
, vol.4
, Issue.12
, pp. 1238-1246
-
-
Traver, D.1
Paw, B.H.2
Poss, K.D.3
Penberthy, W.T.4
Lin, S.5
Zon, L.I.6
-
34
-
-
0035865186
-
The vascular anatomy of the developing zebrafish: An atlas of embryonic and early larval development
-
Isogai S, Horiguchi M, Weinstein BM. The vascular anatomy of the developing zebrafish: an atlas of embryonic and early larval development. Dev Biol. 2001;230(2):278-301.
-
(2001)
Dev Biol.
, vol.230
, Issue.2
, pp. 278-301
-
-
Isogai, S.1
Horiguchi, M.2
Weinstein, B.M.3
-
35
-
-
79955134993
-
Aplexone targets the HMG-CoA reductase pathway and differentially regulates arteriovenous angiogenesis
-
Choi J, et al. Aplexone targets the HMG-CoA reductase pathway and differentially regulates arteriovenous angiogenesis. Development. 2011;138(6):1173-1181.
-
(2011)
Development.
, vol.138
, Issue.6
, pp. 1173-1181
-
-
Choi, J.1
-
36
-
-
0037458569
-
Manipulation of EphB2 regulatory motifs and SH2 binding sites switches MAPK signaling and biological activity
-
Tong J, Elowe S, Nash P, Pawson T. Manipulation of EphB2 regulatory motifs and SH2 binding sites switches MAPK signaling and biological activity. J Biol Chem. 2003;278(8):6111-6119.
-
(2003)
J Biol Chem.
, vol.278
, Issue.8
, pp. 6111-6119
-
-
Tong, J.1
Elowe, S.2
Nash, P.3
Pawson, T.4
-
37
-
-
0242628897
-
Angiogenic network formation in the developing vertebrate trunk
-
Isogai S, Lawson ND, Torrealday S, Horiguchi M, Weinstein BM. Angiogenic network formation in the developing vertebrate trunk. Development. 2003;130(21):5281-5290.
-
(2003)
Development.
, vol.130
, Issue.21
, pp. 5281-5290
-
-
Isogai, S.1
Lawson, N.D.2
Torrealday, S.3
Horiguchi, M.4
Weinstein, B.M.5
-
38
-
-
0036340364
-
Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels
-
Roman BL, et al. Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels. Development. 2002;129(12):3009-3019.
-
(2002)
Development.
, vol.129
, Issue.12
, pp. 3009-3019
-
-
Roman, B.L.1
-
39
-
-
34347220473
-
Defining the role of mTOR in cancer
-
Guertin DA, Sabatini DM. Defining the role of mTOR in cancer. Cancer Cell. 2007;12(1):9-22.
-
(2007)
Cancer Cell
, vol.12
, Issue.1
, pp. 9-22
-
-
Guertin, D.A.1
Sabatini, D.M.2
-
40
-
-
84872229987
-
In parallel interconnectivity of the dorsal longitudinal anastomotic vessels requires both VEGF signaling and circulatory flow
-
Zygmunt T, et al. In parallel interconnectivity of the dorsal longitudinal anastomotic vessels requires both VEGF signaling and circulatory flow. J Cell Sci. 2012;125(pt 21):5159-5167.
-
(2012)
J Cell Sci.
, vol.125
, Issue.PART 21
, pp. 5159-5167
-
-
Zygmunt, T.1
-
41
-
-
65349101151
-
Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941
-
Junttila TT, et al. Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941. Cancer Cell. 2009;15(5):429-440.
-
(2009)
Cancer Cell
, vol.15
, Issue.5
, pp. 429-440
-
-
Junttila, T.T.1
-
42
-
-
51849111524
-
NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations
-
Serra V, et al. NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations. Cancer Res. 2008;68(19):8022-8030.
-
(2008)
Cancer Res.
, vol.68
, Issue.19
, pp. 8022-8030
-
-
Serra, V.1
-
43
-
-
34547810922
-
Phosphatidylinositol 3-kinase (PI3K) inhibitors as anticancer drugs
-
Verheijen JC, Zask A. Phosphatidylinositol 3-kinase (PI3K) inhibitors as anticancer drugs. Drugs Fut. 2007;32(6):537-547.
-
(2007)
Drugs Fut.
, vol.32
, Issue.6
, pp. 537-547
-
-
Verheijen, J.C.1
Zask, A.2
-
44
-
-
33745993633
-
Hyperactivation of mammalian target of rapamycin (mTOR) signaling by a gain-offunction mutant of the Rheb GTPase
-
Yan L, Findlay GM, Jones R, Procter J, Cao Y, Lamb RF. Hyperactivation of mammalian target of rapamycin (mTOR) signaling by a gain-offunction mutant of the Rheb GTPase. J Biol Chem. 2006;281(29):19793-19797.
-
(2006)
J Biol Chem.
, vol.281
, Issue.29
, pp. 19793-19797
-
-
Yan, L.1
Findlay, G.M.2
Jones, R.3
Procter, J.4
Cao, Y.5
Lamb, R.F.6
-
45
-
-
0347318056
-
TSC2: Filling the GAP in the mTOR signaling pathway
-
Li Y, Corradetti MN, Inoki K, Guan KL. TSC2: filling the GAP in the mTOR signaling pathway. Trends Biochem Sci. 2004;29(1):32-38.
-
(2004)
Trends Biochem Sci.
, vol.29
, Issue.1
, pp. 32-38
-
-
Li, Y.1
Corradetti, M.N.2
Inoki, K.3
Guan, K.L.4
-
46
-
-
16644391315
-
Transgenesis and gene trap methods in zebrafish by using the Tol2 transposable element
-
Kawakami K. Transgenesis and gene trap methods in zebrafish by using the Tol2 transposable element. Methods Cell Biol. 2004;77:201-222.
-
(2004)
Methods Cell Biol.
, vol.77
, pp. 201-222
-
-
Kawakami, K.1
-
47
-
-
25444488956
-
Transposon tools and methods in zebrafish
-
Kawakami K. Transposon tools and methods in zebrafish. Dev Dyn. 2005;234(2):244-254.
-
(2005)
Dev Dyn.
, vol.234
, Issue.2
, pp. 244-254
-
-
Kawakami, K.1
-
48
-
-
38449110499
-
Tol2: A versatile gene transfer vector in vertebrates
-
Kawakami K. Tol2: a versatile gene transfer vector in vertebrates. Genome Biol. 2007;8(Suppl 1):S7.
-
(2007)
Genome Biol.
, vol.8
, Issue.SUPPL. 1
-
-
Kawakami, K.1
-
49
-
-
36448963734
-
The Tol2kit: A multisite gateway-based construction kit for Tol2 transposon transgenesis constructs
-
Kwan KM, et al. The Tol2kit: a multisite gateway-based construction kit for Tol2 transposon transgenesis constructs. Dev Dyn. 2007;236(11):3088-3099.
-
(2007)
Dev Dyn.
, vol.236
, Issue.11
, pp. 3088-3099
-
-
Kwan, K.M.1
-
50
-
-
60249088034
-
P120-Ras GTPase activating protein (RasGAP): A multi-interacting protein in downstream signaling
-
Pamonsinlapatham P, et al. P120-Ras GTPase activating protein (RasGAP): a multi-interacting protein in downstream signaling. Biochimie. 2009;91(RasGAP):320-328.
-
(2009)
Biochimie.
, vol.91
, Issue.RASGAP
, pp. 320-328
-
-
Pamonsinlapatham, P.1
-
51
-
-
0030772378
-
The Ras-RasGAP complex: Structural basis for GTPase activation and its loss in oncogenic Ras mutants
-
Scheffzek K, et al. The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants. Science. 1997;277(5324):333- 338.
-
(1997)
Science
, vol.277
, Issue.5324
, pp. 333-338
-
-
Scheffzek, K.1
-
53
-
-
0028333768
-
Sequential protein kinase reactions controlling cell growth and differentiation
-
Johnson GL, Vaillancourt RR. Sequential protein kinase reactions controlling cell growth and differentiation. Curr Opin Cell Biol. 1994;6(2):230-238.
-
(1994)
Curr Opin Cell Biol.
, vol.6
, Issue.2
, pp. 230-238
-
-
Johnson, G.L.1
Vaillancourt, R.R.2
-
54
-
-
0028074316
-
Phosphatidylinositol-3-OH kinase as a direct target of Ras
-
Rodriguez-Viciana P, et al. Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature. 1994;370(6490):527-532.
-
(1994)
Nature
, vol.370
, Issue.6490
, pp. 527-532
-
-
Rodriguez-Viciana, P.1
-
55
-
-
0030605386
-
Phosphatidylinositol 3' kinase: One of the effectors of Ras
-
Rodriguez-Viciana P, Marte BM, Warne PH, Downward J. Phosphatidylinositol 3' kinase: one of the effectors of Ras. Philos Trans R Soc Lond B Biol Sci. 1996;351(1336):225-231.
-
(1996)
Philos Trans R Soc Lond B Biol Sci.
, vol.351
, Issue.1336
, pp. 225-231
-
-
Rodriguez-Viciana, P.1
Marte, B.M.2
Warne, P.H.3
Downward, J.4
-
56
-
-
0029990003
-
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation
-
Rodriguez-Viciana P, Warne PH, Vanhaesebroeck B, Waterfield MD, Downward J. Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation. EMBO J. 1996;15(10):2442-2451.
-
(1996)
EMBO J.
, vol.15
, Issue.10
, pp. 2442-2451
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Vanhaesebroeck, B.3
Waterfield, M.D.4
Downward, J.5
-
57
-
-
79960055459
-
RAS interaction with PI3K: More than just another effector pathway
-
Castellano E, Downward J. RAS interaction with PI3K: more than just another effector pathway. Genes Cancer. 2011;2(3):261-274.
-
(2011)
Genes Cancer
, vol.2
, Issue.3
, pp. 261-274
-
-
Castellano, E.1
Downward, J.2
-
58
-
-
59149089644
-
Artery and vein size is balanced by Notch and ephrin B2/EphB4 during angiogenesis
-
Kim YH, Hu H, Guevara-Gallardo S, Lam MT, Fong SY, Wang RA. Artery and vein size is balanced by Notch and ephrin B2/EphB4 during angiogenesis. Development. 2008;135(22):3755-3764.
-
(2008)
Development.
, vol.135
, Issue.22
, pp. 3755-3764
-
-
Kim, Y.H.1
Hu, H.2
Guevara-Gallardo, S.3
Lam, M.T.4
Fong, S.Y.5
Wang, R.A.6
-
59
-
-
70349856167
-
Arterial-venous segregation by selective cell sprouting: An alternative mode of blood vessel formation
-
Herbert SP, et al. Arterial-venous segregation by selective cell sprouting: an alternative mode of blood vessel formation. Science. 2009;326(5950):294-298.
-
(2009)
Science
, vol.326
, Issue.5950
, pp. 294-298
-
-
Herbert, S.P.1
-
60
-
-
0028110068
-
Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity
-
Davis S, et al. Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity. Science. 1994;266(5186):816-819.
-
(1994)
Science
, vol.266
, Issue.5186
, pp. 816-819
-
-
Davis, S.1
-
61
-
-
76749124339
-
Rapamycin (sirolimus) in tuberous sclerosis associated pediatric central nervous system tumors
-
Lam C, Bouffet E, Tabori U, Mabbott D, Taylor M, Bartels U. Rapamycin (sirolimus) in tuberous sclerosis associated pediatric central nervous system tumors. Pediatr Blood Cancer. 2010;54(3):476-479.
-
(2010)
Pediatr Blood Cancer
, vol.54
, Issue.3
, pp. 476-479
-
-
Lam, C.1
Bouffet, E.2
Tabori, U.3
Mabbott, D.4
Taylor, M.5
Bartels, U.6
-
62
-
-
80052651179
-
Sirolimus for the treatment of complicated vascular anomalies in children
-
Hammill AM, et al. Sirolimus for the treatment of complicated vascular anomalies in children. Pediatr Blood Cancer. 2011;57(6):1018-1024.
-
(2011)
Pediatr Blood Cancer
, vol.57
, Issue.6
, pp. 1018-1024
-
-
Hammill, A.M.1
-
63
-
-
61349168351
-
A mechanosensitive transcriptional mechanism that controls angiogenesis
-
Mammoto A, et al. A mechanosensitive transcriptional mechanism that controls angiogenesis. Nature. 2009;457(7233):1103-1108.
-
(2009)
Nature
, vol.457
, Issue.7233
, pp. 1103-1108
-
-
Mammoto, A.1
-
64
-
-
70350036077
-
Quantification of oxygeninduced retinopathy in the mouse: A model of vessel loss, vessel regrowth and pathological angiogenesis
-
Connor KM, et al. Quantification of oxygeninduced retinopathy in the mouse: a model of vessel loss, vessel regrowth and pathological angiogenesis. Nat Protoc. 2009;4(11):1565-1573.
-
(2009)
Nat Protoc.
, vol.4
, Issue.11
, pp. 1565-1573
-
-
Connor, K.M.1
-
65
-
-
80052838996
-
EphrinA/EphA signal facilitates insulin-like growth factor-I-induced myogenic differentiation through suppression of the Ras/extracellular signal-regulated kinase 1/2 cascade in myoblast cell lines
-
Minami M, Koyama T, Wakayama Y, Fukuhara S, Mochizuki N. EphrinA/EphA signal facilitates insulin-like growth factor-I-induced myogenic differentiation through suppression of the Ras/extracellular signal-regulated kinase 1/2 cascade in myoblast cell lines. Mol Biol Cell. 2011;22(18):3508-3519.
-
(2011)
Mol Biol Cell
, vol.22
, Issue.18
, pp. 3508-3519
-
-
Minami, M.1
Koyama, T.2
Wakayama, Y.3
Fukuhara, S.4
Mochizuki, N.5
-
66
-
-
57649221000
-
Ephrin-B2-induced cleavage of EphB2 receptor is mediated by matrix metalloproteinases to trigger cell repulsion
-
Lin KT, Sloniowski S, Ethell DW, Ethell IM. Ephrin-B2-induced cleavage of EphB2 receptor is mediated by matrix metalloproteinases to trigger cell repulsion. J Biol Chem. 2008;283(43):28969-28979.
-
(2008)
J Biol Chem.
, vol.283
, Issue.43
, pp. 28969-28979
-
-
Lin, K.T.1
Sloniowski, S.2
Ethell, D.W.3
Ethell, I.M.4
-
67
-
-
34547645033
-
Identification of S664 TSC2 phosphorylation as a marker for extracellular signalregulated kinase mediated mTOR activation in tuberous sclerosis and human cancer
-
Ma L, et al. Identification of S664 TSC2 phosphorylation as a marker for extracellular signalregulated kinase mediated mTOR activation in tuberous sclerosis and human cancer. Cancer Res. 2007;67(15):7106-7112.
-
(2007)
Cancer Res.
, vol.67
, Issue.15
, pp. 7106-7112
-
-
Ma, L.1
-
68
-
-
0035875829
-
Morphogenesis of prechordal plate and notochord requires intact Eph/ephrin B signaling
-
Chan J, et al. Morphogenesis of prechordal plate and notochord requires intact Eph/ephrin B signaling. Dev Biol. 2001;234(2):470-482.
-
(2001)
Dev Biol.
, vol.234
, Issue.2
, pp. 470-482
-
-
Chan, J.1
-
69
-
-
0036527350
-
Dissection of angiogenic signaling in zebrafish using a chemical genetic approach
-
Chan J, Bayliss PE, Wood JM, Roberts TM. Dissection of angiogenic signaling in zebrafish using a chemical genetic approach. Cancer Cell. 2002;1(3):257-267.
-
(2002)
Cancer Cell
, vol.1
, Issue.3
, pp. 257-267
-
-
Chan, J.1
Bayliss, P.E.2
Wood, J.M.3
Roberts, T.M.4
|