β1-integrin-dependent migration of microglia in response to neuron-released α-synuclein

Experimental and Molecular Medicine

Volumn 46, Issue 4, 2014, Pages

  Kim, Changyoun ^a   Cho, Eun Deok ^b   Kim, Hyung Koo ^a   You, Sungyong ^c   Lee, He Jin ^a,b   Hwang, Daehee ^d   Lee, Seung Jae ^a  

^a Konkuk University   (South Korea)

^b Konkuk University School of Medicine   (South Korea)

^c CEDARS SINAI MEDICAL CENTER   (United States)

^d Pohang University of Science and Technology (POSTECH)   (South Korea)

Author keywords

Microglial migration; Neuroinflammation; Parkinson's disease; synuclein; 1 integrin

Indexed keywords

ALPHA SYNUCLEIN; ALPHA5 INTEGRIN; BETA ACTIN; BETA1 INTEGRIN; GELATINASE B; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BETA ACTIN GENE; CELL ACTIVATION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; GAPDH GENE; GENE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; ICAM 1 GENE; IL 1 BETA GENE; ITGA5 GENE; MICROGLIA; MMP9 GENE; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; NOS2 GENE; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; RAC1 GENE; RAT; SCIN GENE; SIGNAL TRANSDUCTION; TNF ALPHA GENE; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL MOTION; CULTURE MEDIUM; DRUG EFFECT; GENE REGULATORY NETWORK; GENETICS; METABOLISM; NERVE CELL; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TUMOR CELL LINE;

ALPHA-SYNUCLEIN; ANIMALS; ANTIGENS, CD29; CELL LINE, TUMOR; CELL MOVEMENT; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; GENE REGULATORY NETWORKS; HUMANS; MICE; MICE, INBRED C57BL; MICROGLIA; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2;

EID: 84902162560     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2014.6     Document Type: Article

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