-
3
-
-
0036230510
-
Local lymph node assay - validation, conduct and use in practice
-
Basketter DA, Evans P, Fielder RJ, Gerberick GF, Dearman RJ, Kimber I. Local lymph node assay - validation, conduct and use in practice. Food Chem Toxicol 2002;40:593-8.
-
(2002)
Food Chem Toxicol
, vol.40
, pp. 593-598
-
-
Basketter, D.A.1
Evans, P.2
Fielder, R.J.3
Gerberick, G.F.4
Dearman, R.J.5
Kimber, I.6
-
4
-
-
0014480637
-
The identification of contact allergens by animal assay. The guinea pig maximization test
-
Magnusson B, Kligman AM. The identification of contact allergens by animal assay. The guinea pig maximization test. J Invest Dermatol 1969;52:268-76.
-
(1969)
J Invest Dermatol
, vol.52
, pp. 268-276
-
-
Magnusson, B.1
Kligman, A.M.2
-
5
-
-
84902089009
-
-
76/768/EEC CD.
-
76/768/EEC CD. http://ec.europa.eu/consumers/sectors/cosmetics/documents/directive/index_en.htm/February2014.
-
-
-
-
6
-
-
30144443263
-
Compilation of historical local lymph node data for evaluation of skin sensitization alternative methods
-
Gerberick GF, Ryan CA, Kern PS, Schlatter H, Dearman RJ, Kimber I et al. Compilation of historical local lymph node data for evaluation of skin sensitization alternative methods. Dermatitis 2005;16:157-202.
-
(2005)
Dermatitis
, vol.16
, pp. 157-202
-
-
Gerberick, G.F.1
Ryan, C.A.2
Kern, P.S.3
Schlatter, H.4
Dearman, R.J.5
Kimber, I.6
-
7
-
-
76149142138
-
Local lymph node data for the evaluation of skin sensitization alternatives: a second compilation
-
Kern PS, Gerberick GF, Ryan CA, Kimber I, Aptula A, Basketter DA. Local lymph node data for the evaluation of skin sensitization alternatives: a second compilation. Dermatitis 2010;21:8-32.
-
(2010)
Dermatitis
, vol.21
, pp. 8-32
-
-
Kern, P.S.1
Gerberick, G.F.2
Ryan, C.A.3
Kimber, I.4
Aptula, A.5
Basketter, D.A.6
-
8
-
-
85025418671
-
Studies on the sensitization of animals with simple chemical compounds: Iii. Anaphylaxis induced by Arsphenamine
-
Landsteiner K, Jacobs J. Studies on the sensitization of animals with simple chemical compounds: Iii. Anaphylaxis induced by Arsphenamine. J Exp Med 1936;64:717-21.
-
(1936)
J Exp Med
, vol.64
, pp. 717-721
-
-
Landsteiner, K.1
Jacobs, J.2
-
9
-
-
79958838434
-
Caged fluorescent haptens reveal the generation of cryptic epitopes in allergic contact dermatitis
-
Simonsson C, Andersson SI, Stenfeldt AL, Bergstrom J, Bauer B, Jonsson CA et al. Caged fluorescent haptens reveal the generation of cryptic epitopes in allergic contact dermatitis. J Invest Dermatol 2011;131:1486-93.
-
(2011)
J Invest Dermatol
, vol.131
, pp. 1486-1493
-
-
Simonsson, C.1
Andersson, S.I.2
Stenfeldt, A.L.3
Bergstrom, J.4
Bauer, B.5
Jonsson, C.A.6
-
11
-
-
67651085458
-
Langerhans cell migration: not necessarily always at the center of the skin sensitization universe
-
Kimber I, Cumberbatch M, Dearman RJ. Langerhans cell migration: not necessarily always at the center of the skin sensitization universe. J Invest Dermatol 2009;129:1852-3.
-
(2009)
J Invest Dermatol
, vol.129
, pp. 1852-1853
-
-
Kimber, I.1
Cumberbatch, M.2
Dearman, R.J.3
-
12
-
-
0038216863
-
IL-1beta-induced Langerhans' cell migration and TNF-alpha production in human skin: regulation by lactoferrin
-
Cumberbatch M, Bhushan M, Dearman RJ, Kimber I, Griffiths CE. IL-1beta-induced Langerhans' cell migration and TNF-alpha production in human skin: regulation by lactoferrin. Clin Exp Immunol 2003;132:352-9.
-
(2003)
Clin Exp Immunol
, vol.132
, pp. 352-359
-
-
Cumberbatch, M.1
Bhushan, M.2
Dearman, R.J.3
Kimber, I.4
Griffiths, C.E.5
-
13
-
-
0032792699
-
Tumour necrosis factor-alpha induces Langerhans cell migration in humans
-
Cumberbatch M, Griffiths CE, Tucker SC, Dearman RJ, Kimber I. Tumour necrosis factor-alpha induces Langerhans cell migration in humans. Br J Dermatol 1999;141:192-200.
-
(1999)
Br J Dermatol
, vol.141
, pp. 192-200
-
-
Cumberbatch, M.1
Griffiths, C.E.2
Tucker, S.C.3
Dearman, R.J.4
Kimber, I.5
-
15
-
-
0029913787
-
T cell populations primed by hapten sensitization in contact sensitivity are distinguished by polarized patterns of cytokine production: interferon gamma-producing (Tc1) effector CD8+ T cells and interleukin (Il) 4/Il-10-producing (Th2) negative regulatory CD4+ T cells
-
Xu H, DiIulio NA, Fairchild RL. T cell populations primed by hapten sensitization in contact sensitivity are distinguished by polarized patterns of cytokine production: interferon gamma-producing (Tc1) effector CD8+ T cells and interleukin (Il) 4/Il-10-producing (Th2) negative regulatory CD4+ T cells. J Exp Med 1996;183:1001-12.
-
(1996)
J Exp Med
, vol.183
, pp. 1001-1012
-
-
Xu, H.1
DiIulio, N.A.2
Fairchild, R.L.3
-
16
-
-
3042663180
-
T lymphocyte-mediated immune responses to chemical haptens and metal ions: implications for allergic and autoimmune disease
-
Martin SF. T lymphocyte-mediated immune responses to chemical haptens and metal ions: implications for allergic and autoimmune disease. Int Arch Allergy Immunol 2004;134:186-98.
-
(2004)
Int Arch Allergy Immunol
, vol.134
, pp. 186-198
-
-
Martin, S.F.1
-
17
-
-
0034925388
-
Effector and regulatory T cells in allergic contact dermatitis
-
Cavani A, Albanesi C, Traidl C, Sebastiani S, Girolomoni G. Effector and regulatory T cells in allergic contact dermatitis. Trends Immunol 2001;22:118-20.
-
(2001)
Trends Immunol
, vol.22
, pp. 118-120
-
-
Cavani, A.1
Albanesi, C.2
Traidl, C.3
Sebastiani, S.4
Girolomoni, G.5
-
18
-
-
0034254650
-
Early local generation of C5a initiates the elicitation of contact sensitivity by leading to early T cell recruitment
-
Tsuji RF, Kawikova I, Ramabhadran R, Akahira-Azuma M, Taub D, Hugli TE et al. Early local generation of C5a initiates the elicitation of contact sensitivity by leading to early T cell recruitment. J Immunol 2000;165:1588-98.
-
(2000)
J Immunol
, vol.165
, pp. 1588-1598
-
-
Tsuji, R.F.1
Kawikova, I.2
Ramabhadran, R.3
Akahira-Azuma, M.4
Taub, D.5
Hugli, T.E.6
-
19
-
-
0034798403
-
A cytokine-to-chemokine axis between T lymphocytes and keratinocytes can favor Th1 cell accumulation in chronic inflammatory skin diseases
-
Albanesi C, Scarponi C, Sebastiani S, Cavani A, Federici M, Sozzani S et al. A cytokine-to-chemokine axis between T lymphocytes and keratinocytes can favor Th1 cell accumulation in chronic inflammatory skin diseases. J Leukoc Biol 2001;70:617-23.
-
(2001)
J Leukoc Biol
, vol.70
, pp. 617-623
-
-
Albanesi, C.1
Scarponi, C.2
Sebastiani, S.3
Cavani, A.4
Federici, M.5
Sozzani, S.6
-
20
-
-
0032191916
-
An innate sense of danger
-
Matzinger P. An innate sense of danger. Semin Immunol 1998;10:399-415.
-
(1998)
Semin Immunol
, vol.10
, pp. 399-415
-
-
Matzinger, P.1
-
21
-
-
74549167783
-
Regulation of adaptive immunity by the innate immune system
-
Iwasaki A, Medzhitov R. Regulation of adaptive immunity by the innate immune system. Science 2010;327:291-5.
-
(2010)
Science
, vol.327
, pp. 291-295
-
-
Iwasaki, A.1
Medzhitov, R.2
-
22
-
-
51049124690
-
Toll-like receptor and IL-12 signaling control susceptibility to contact hypersensitivity
-
Martin SF, Dudda JC, Bachtanian E, Lembo A, Liller S, Durr C et al. Toll-like receptor and IL-12 signaling control susceptibility to contact hypersensitivity. J Exp Med 2008;205:2151-62.
-
(2008)
J Exp Med
, vol.205
, pp. 2151-2162
-
-
Martin, S.F.1
Dudda, J.C.2
Bachtanian, E.3
Lembo, A.4
Liller, S.5
Durr, C.6
-
23
-
-
77955886553
-
Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel
-
Schmidt M, Raghavan B, Muller V, Vogl T, Fejer G, Tchaptchet S et al. Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel. Nat Immunol 2010;11:814-9.
-
(2010)
Nat Immunol
, vol.11
, pp. 814-819
-
-
Schmidt, M.1
Raghavan, B.2
Muller, V.3
Vogl, T.4
Fejer, G.5
Tchaptchet, S.6
-
24
-
-
33644985564
-
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1
-
Sutterwala FS, Ogura Y, Szczepanik M, Lara-Tejero M, Lichtenberger GS, Grant EP et al. Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 2006;24:317-27.
-
(2006)
Immunity
, vol.24
, pp. 317-327
-
-
Sutterwala, F.S.1
Ogura, Y.2
Szczepanik, M.3
Lara-Tejero, M.4
Lichtenberger, G.S.5
Grant, E.P.6
-
25
-
-
34250792190
-
Activation of the IL-1beta-processing inflammasome is involved in contact hypersensitivity
-
Watanabe H, Gaide O, Petrilli V, Martinon F, Contassot E, Roques S et al. Activation of the IL-1beta-processing inflammasome is involved in contact hypersensitivity. J Invest Dermatol 2007;127:1956-63.
-
(2007)
J Invest Dermatol
, vol.127
, pp. 1956-1963
-
-
Watanabe, H.1
Gaide, O.2
Petrilli, V.3
Martinon, F.4
Contassot, E.5
Roques, S.6
-
26
-
-
84864361826
-
Contact sensitizers induce skin inflammation via ROS production and hyaluronic acid degradation
-
Esser PR, Wolfle U, Durr C, von Loewenich FD, Schempp CM, Freudenberg MA et al. Contact sensitizers induce skin inflammation via ROS production and hyaluronic acid degradation. PLoS ONE 2012;7:e41340.
-
(2012)
PLoS ONE
, vol.7
-
-
Esser, P.R.1
Wolfle, U.2
Durr, C.3
von Loewenich, F.D.4
Schempp, C.M.5
Freudenberg, M.A.6
-
27
-
-
79959462242
-
Impact of aryl hydrocarbon receptor (AhR) knockdown on cell cycle progression in human HaCaT keratinocytes
-
Kalmes M, Hennen J, Clemens J, Blomeke B. Impact of aryl hydrocarbon receptor (AhR) knockdown on cell cycle progression in human HaCaT keratinocytes. Biol Chem 2011;392:643-51.
-
(2011)
Biol Chem
, vol.392
, pp. 643-651
-
-
Kalmes, M.1
Hennen, J.2
Clemens, J.3
Blomeke, B.4
-
28
-
-
79952637507
-
Active transport of contact allergens in human monocyte-derived dendritic cells is mediated by multidrug resistance related proteins
-
Skazik C, Heise R, Ott H, Czaja K, Marquardt Y, Merk HF et al. Active transport of contact allergens in human monocyte-derived dendritic cells is mediated by multidrug resistance related proteins. Arch Biochem Biophys 2011;508:212-6.
-
(2011)
Arch Biochem Biophys
, vol.508
, pp. 212-216
-
-
Skazik, C.1
Heise, R.2
Ott, H.3
Czaja, K.4
Marquardt, Y.5
Merk, H.F.6
-
29
-
-
0001267196
-
Delayed contact hypersensitivity in the Guinea pig
-
Buehler EV. Delayed contact hypersensitivity in the Guinea pig. Arch Dermatol 1965;91:171-7.
-
(1965)
Arch Dermatol
, vol.91
, pp. 171-177
-
-
Buehler, E.V.1
-
30
-
-
84902076075
-
The adverse outcome pathway for skin sensitisation initiated by covalent binding to proteins
-
HaSPSoTaA OE. The adverse outcome pathway for skin sensitisation initiated by covalent binding to proteins. 2012;168:1-59. http://search.oecd.org/officialdocuments/displaydocumentpdf/?cote=env/jm/mono%282012%2910/part1&doclanguage=en/February2014.
-
(2012)
, vol.168
, pp. 1-59
-
-
Haspsotaa, O.E.1
-
31
-
-
5744253935
-
Development of a peptide reactivity assay for screening contact allergens
-
Gerberick GF, Vassallo JD, Bailey RE, Chaney JG, Morrall SW, Lepoittevin JP. Development of a peptide reactivity assay for screening contact allergens. Toxicol Sci 2004;81:332-43.
-
(2004)
Toxicol Sci
, vol.81
, pp. 332-343
-
-
Gerberick, G.F.1
Vassallo, J.D.2
Bailey, R.E.3
Chaney, J.G.4
Morrall, S.W.5
Lepoittevin, J.P.6
-
32
-
-
79961120567
-
A genomic biomarker signature can predict skin sensitizers using a cell-based in vitro alternative to animal tests
-
Johansson H, Lindstedt M, Albrekt AS, Borrebaeck CA. A genomic biomarker signature can predict skin sensitizers using a cell-based in vitro alternative to animal tests. BMC Genomics 2011;12:399.
-
(2011)
BMC Genomics
, vol.12
, pp. 399
-
-
Johansson, H.1
Lindstedt, M.2
Albrekt, A.S.3
Borrebaeck, C.A.4
-
33
-
-
82755173987
-
Pattern rules: biomarker signatures for sensitization as an alternative to animal testing
-
Lindstedt M, Borrebaeck C. Pattern rules: biomarker signatures for sensitization as an alternative to animal testing. Biomark Med 2011;5:809-11.
-
(2011)
Biomark Med
, vol.5
, pp. 809-811
-
-
Lindstedt, M.1
Borrebaeck, C.2
-
34
-
-
84884702882
-
A dataset on 145 chemicals tested in alternative assays for skin sensitization undergoing prevalidation
-
doi: 10.1002/jat.2869.
-
Natsch A, Ryan CA, Foertsch L, Emter R, Jaworska J, Gerberick F et al. A dataset on 145 chemicals tested in alternative assays for skin sensitization undergoing prevalidation. J Appl Toxicol 2013; doi: 10.1002/jat.2869.
-
(2013)
J Appl Toxicol
-
-
Natsch, A.1
Ryan, C.A.2
Foertsch, L.3
Emter, R.4
Jaworska, J.5
Gerberick, F.6
-
35
-
-
33745450390
-
Development of an in vitro skin sensitization test using human cell lines: the human Cell Line Activation Test (h-CLAT). I. Optimization of the h-CLAT protocol
-
Ashikaga T, Yoshida Y, Hirota M, Yoneyama K, Itagaki H, Sakaguchi H et al. Development of an in vitro skin sensitization test using human cell lines: the human Cell Line Activation Test (h-CLAT). I. Optimization of the h-CLAT protocol. Toxicol In Vitro 2006;20:767-73.
-
(2006)
Toxicol In Vitro
, vol.20
, pp. 767-773
-
-
Ashikaga, T.1
Yoshida, Y.2
Hirota, M.3
Yoneyama, K.4
Itagaki, H.5
Sakaguchi, H.6
-
36
-
-
81155152595
-
Predictive performance for human skin sensitizing potential of the human cell line activation test (h-CLAT)
-
Nukada Y, Ashikaga T, Sakaguchi H, Sono S, Mugita N, Hirota M et al. Predictive performance for human skin sensitizing potential of the human cell line activation test (h-CLAT). Contact Dermat 2011;65:343-53.
-
(2011)
Contact Dermat
, vol.65
, pp. 343-353
-
-
Nukada, Y.1
Ashikaga, T.2
Sakaguchi, H.3
Sono, S.4
Mugita, N.5
Hirota, M.6
-
37
-
-
77956173929
-
Predicting skin sensitization potential and inter-laboratory reproducibility of a human Cell Line Activation Test (h-CLAT) in the European Cosmetics Association (COLIPA) ring trials
-
Sakaguchi H, Ryan C, Ovigne JM, Schroeder KR, Ashikaga T. Predicting skin sensitization potential and inter-laboratory reproducibility of a human Cell Line Activation Test (h-CLAT) in the European Cosmetics Association (COLIPA) ring trials. Toxicol In Vitro 2010;24:1810-20.
-
(2010)
Toxicol In Vitro
, vol.24
, pp. 1810-1820
-
-
Sakaguchi, H.1
Ryan, C.2
Ovigne, J.M.3
Schroeder, K.R.4
Ashikaga, T.5
-
38
-
-
48649106638
-
A cell-based in vitro alternative to identify skin sensitizers by gene expression
-
Hooyberghs J, Schoeters E, Lambrechts N, Nelissen I, Witters H, Schoeters G et al. A cell-based in vitro alternative to identify skin sensitizers by gene expression. Toxicol Appl Pharmacol 2008;231:103-11.
-
(2008)
Toxicol Appl Pharmacol
, vol.231
, pp. 103-111
-
-
Hooyberghs, J.1
Schoeters, E.2
Lambrechts, N.3
Nelissen, I.4
Witters, H.5
Schoeters, G.6
-
39
-
-
79955481875
-
Functionality and specificity of gene markers for skin sensitization in dendritic cells
-
Lambrechts N, Nelissen I, Van Tendeloo V, Witters H, Van Den Heuvel R, Hooyberghs J et al. Functionality and specificity of gene markers for skin sensitization in dendritic cells. Toxicol Lett 2011;203:106-10.
-
(2011)
Toxicol Lett
, vol.203
, pp. 106-110
-
-
Lambrechts, N.1
Nelissen, I.2
Van Tendeloo, V.3
Witters, H.4
Van Den Heuvel, R.5
Hooyberghs, J.6
-
41
-
-
34547500757
-
An evaluation of selected global (Q)SARs/expert systems for the prediction of skin sensitisation potential
-
Patlewicz G, Aptula AO, Uriarte E, Roberts DW, Kern PS, Gerberick GF et al. An evaluation of selected global (Q)SARs/expert systems for the prediction of skin sensitisation potential. SAR QSAR Environ Res 2007;18:515-41.
-
(2007)
SAR QSAR Environ Res
, vol.18
, pp. 515-541
-
-
Patlewicz, G.1
Aptula, A.O.2
Uriarte, E.3
Roberts, D.W.4
Kern, P.S.5
Gerberick, G.F.6
-
42
-
-
84887828102
-
Computer models versus reality: how well do in silico models currently predict the sensitization potential of a substance
-
Teubner W, Mehling A, Schuster PX, Guth K, Worth A, Burton J et al. Computer models versus reality: how well do in silico models currently predict the sensitization potential of a substance. Regul Toxicol Pharmacol 2013;67:468-85.
-
(2013)
Regul Toxicol Pharmacol
, vol.67
, pp. 468-485
-
-
Teubner, W.1
Mehling, A.2
Schuster, P.X.3
Guth, K.4
Worth, A.5
Burton, J.6
-
43
-
-
70449637644
-
Overcoming barriers to validation of non-animal partial replacement methods/integrated testing strategies: the report of an EPAA-ECVAM workshop
-
Kinsner-Ovaskainen A, Akkan Z, Casati S, Coecke S, Corvi R, Dal Negro G et al. Overcoming barriers to validation of non-animal partial replacement methods/integrated testing strategies: the report of an EPAA-ECVAM workshop. Altern Lab Anim 2009;37:437-44.
-
(2009)
Altern Lab Anim
, vol.37
, pp. 437-444
-
-
Kinsner-Ovaskainen, A.1
Akkan, Z.2
Casati, S.3
Coecke, S.4
Corvi, R.5
Dal Negro, G.6
-
44
-
-
84866513233
-
Report of the EPAA-ECVAM workshop on the validation of Integrated Testing Strategies (ITS)
-
Kinsner-Ovaskainen A, Maxwell G, Kreysa J, Barroso J, Adriaens E, Alepee N et al. Report of the EPAA-ECVAM workshop on the validation of Integrated Testing Strategies (ITS). Altern Lab Anim 2012;40:175-81.
-
(2012)
Altern Lab Anim
, vol.40
, pp. 175-181
-
-
Kinsner-Ovaskainen, A.1
Maxwell, G.2
Kreysa, J.3
Barroso, J.4
Adriaens, E.5
Alepee, N.6
-
45
-
-
33748801463
-
Toward an evidence-based toxicology
-
Hoffmann S, Hartung T. Toward an evidence-based toxicology. Hum Exp Toxicol 2006;25:497-513.
-
(2006)
Hum Exp Toxicol
, vol.25
, pp. 497-513
-
-
Hoffmann, S.1
Hartung, T.2
-
46
-
-
84884699708
-
Bayesian integrated testing strategy to assess skin sensitization potency: from theory to practice
-
doi: 10.1002/jat.2869.
-
Jaworska J, Dancik Y, Kern P, Gerberick F, Natsch A. Bayesian integrated testing strategy to assess skin sensitization potency: from theory to practice. J Appl Toxicol 2013; doi: 10.1002/jat.2869.
-
(2013)
J Appl Toxicol
-
-
Jaworska, J.1
Dancik, Y.2
Kern, P.3
Gerberick, F.4
Natsch, A.5
-
47
-
-
79960928365
-
Intralaboratory validation of four in vitro assays for the prediction of the skin sensitizing potential of chemicals
-
Bauch C, Kolle SN, Fabian E, Pachel C, Ramirez T, Wiench B et al. Intralaboratory validation of four in vitro assays for the prediction of the skin sensitizing potential of chemicals. Toxicol In Vitro 2011;25:1162-8.
-
(2011)
Toxicol In Vitro
, vol.25
, pp. 1162-1168
-
-
Bauch, C.1
Kolle, S.N.2
Fabian, E.3
Pachel, C.4
Ramirez, T.5
Wiench, B.6
|