-
1
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A., Xu S., Montgomery M.K., Kostas S.A., Driver S.E., Mello C.C. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998, 391:806-811.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
2
-
-
77953609202
-
Engineering RNA for targeted siRNA delivery and medical application
-
Guo P., Coban O., Snead N.M., Trebley J., Hoeprich S., Guo S., et al. Engineering RNA for targeted siRNA delivery and medical application. Adv Drug Deliv Rev 2010, 62:650-666.
-
(2010)
Adv Drug Deliv Rev
, vol.62
, pp. 650-666
-
-
Guo, P.1
Coban, O.2
Snead, N.M.3
Trebley, J.4
Hoeprich, S.5
Guo, S.6
-
3
-
-
68949208465
-
Nanocarriers' entry into the cell: relevance to drug delivery
-
Hillaireau H., Couvreur P. Nanocarriers' entry into the cell: relevance to drug delivery. Cell Mol Life Sci 2009, 66:2873-2896.
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 2873-2896
-
-
Hillaireau, H.1
Couvreur, P.2
-
4
-
-
84865163864
-
Cellular uptake pathways of lipid-modified cationic polymers in gene delivery to primary cells
-
Hsu C.Y., Uludag H. Cellular uptake pathways of lipid-modified cationic polymers in gene delivery to primary cells. Biomaterials 2012, 33:7834-7848.
-
(2012)
Biomaterials
, vol.33
, pp. 7834-7848
-
-
Hsu, C.Y.1
Uludag, H.2
-
5
-
-
77951168054
-
Breaking down the barriers: siRNA delivery and endosome escape
-
Dominska M., Dykxhoorn D.M. Breaking down the barriers: siRNA delivery and endosome escape. JCell Sci 2010, 123:1183-1189.
-
(2010)
JCell Sci
, vol.123
, pp. 1183-1189
-
-
Dominska, M.1
Dykxhoorn, D.M.2
-
6
-
-
0029160083
-
Aversatile vector for gene and oligonucleotide transfer into cells in culture and invivo: polyethylenimine
-
Boussif O., Lezoualc'h F., Zanta M.A., Mergny M.D., Scherman D., Demeneix B., et al. Aversatile vector for gene and oligonucleotide transfer into cells in culture and invivo: polyethylenimine. Proc Natl Acad Sci U S A 1995, 92:7297-7301.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 7297-7301
-
-
Boussif, O.1
Lezoualc'h, F.2
Zanta, M.A.3
Mergny, M.D.4
Scherman, D.5
Demeneix, B.6
-
7
-
-
0035845733
-
Stability of PEI-DNA and DOTAP-DNA complexes: effect of alkaline pH, heparin and serum
-
Moret I., Esteban-Peris J., Guillem V.M., Benet M., Revert F., Dasi F., et al. Stability of PEI-DNA and DOTAP-DNA complexes: effect of alkaline pH, heparin and serum. JControl Release 2001, 76:169-181.
-
(2001)
JControl Release
, vol.76
, pp. 169-181
-
-
Moret, I.1
Esteban-Peris, J.2
Guillem, V.M.3
Benet, M.4
Revert, F.5
Dasi, F.6
-
9
-
-
0342929614
-
Nonphysical sampling distributions in Monte Carlo free-energy estimation: umbrella sampling
-
Torrie G.M., Valleau J.P. Nonphysical sampling distributions in Monte Carlo free-energy estimation: umbrella sampling. JComput Phys 1977, 23:187-199.
-
(1977)
JComput Phys
, vol.23
, pp. 187-199
-
-
Torrie, G.M.1
Valleau, J.P.2
-
10
-
-
84986519238
-
The weighted histogram analysis method for free-energy calculations on biomolecules. I. The method
-
Kumar S., Rosenberg J.M., Bouzida D., Swendsen R.H., Kollman P.A. The weighted histogram analysis method for free-energy calculations on biomolecules. I. The method. JComput Chem 1992, 13:1011-1021.
-
(1992)
JComput Chem
, vol.13
, pp. 1011-1021
-
-
Kumar, S.1
Rosenberg, J.M.2
Bouzida, D.3
Swendsen, R.H.4
Kollman, P.A.5
-
12
-
-
0017100947
-
Theoretical studies of enzymic reactions: dielectric, electrostatic and steric stabilization of the carbonium ion in the reaction of lysozyme
-
Warshel A., Levitt M. Theoretical studies of enzymic reactions: dielectric, electrostatic and steric stabilization of the carbonium ion in the reaction of lysozyme. JMol Biol 1976, 103:227-249.
-
(1976)
JMol Biol
, vol.103
, pp. 227-249
-
-
Warshel, A.1
Levitt, M.2
-
13
-
-
84934443630
-
Introduction to QM/MM simulations
-
Springer, New York, [Chapter 3]
-
Groenhof G. Introduction to QM/MM simulations. Biomolecular simulations: methods and protocols 2013, vol. 924. Springer, New York, [Chapter 3].
-
(2013)
Biomolecular simulations: methods and protocols
, vol.924
-
-
Groenhof, G.1
-
14
-
-
84861773417
-
Coarse-grained molecular simulations of large biomolecules
-
Takada S. Coarse-grained molecular simulations of large biomolecules. Curr Opin Struct Biol 2012, 22:130-137.
-
(2012)
Curr Opin Struct Biol
, vol.22
, pp. 130-137
-
-
Takada, S.1
-
16
-
-
0035906709
-
Spermine: an "invisible" component in the crystals of B-DNA. A grand canonical Monte Carlo and molecular dynamics simulation study
-
Korolev N., Lyubartsev A.P., Nordenskiold L., Laaksonen A. Spermine: an "invisible" component in the crystals of B-DNA. A grand canonical Monte Carlo and molecular dynamics simulation study. JMol Biol 2001, 308:907-917.
-
(2001)
JMol Biol
, vol.308
, pp. 907-917
-
-
Korolev, N.1
Lyubartsev, A.P.2
Nordenskiold, L.3
Laaksonen, A.4
-
17
-
-
0036106375
-
On the competition between water, sodium ions, and spermine in binding to DNA: a molecular dynamics computer simulation study
-
Korolev N., Lyubartsev A.P., Laaksonen A., Nordenskiold L. On the competition between water, sodium ions, and spermine in binding to DNA: a molecular dynamics computer simulation study. Biophys J 2002, 82:2860-2875.
-
(2002)
Biophys J
, vol.82
, pp. 2860-2875
-
-
Korolev, N.1
Lyubartsev, A.P.2
Laaksonen, A.3
Nordenskiold, L.4
-
18
-
-
0344011142
-
Amolecular dynamics simulation study of oriented DNA with polyamine and sodium counterions: diffusion and averaged binding of water and cations
-
Korolev N., Lyubartsev A.P., Laaksonen A., Nordenskiold L. Amolecular dynamics simulation study of oriented DNA with polyamine and sodium counterions: diffusion and averaged binding of water and cations. Nucleic Acids Res 2003, 31:5971-5981.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 5971-5981
-
-
Korolev, N.1
Lyubartsev, A.P.2
Laaksonen, A.3
Nordenskiold, L.4
-
19
-
-
11244319427
-
Amolecular dynamics simulation study of polyamine- and sodium-DANN: interplay between polyamine binding and DNA structure
-
Korolev N., Lyubartsev A.P., Laaksonen A., Nordenskiold L. Amolecular dynamics simulation study of polyamine- and sodium-DANN: interplay between polyamine binding and DNA structure. Eur Biophys J 2004, 33:671-682.
-
(2004)
Eur Biophys J
, vol.33
, pp. 671-682
-
-
Korolev, N.1
Lyubartsev, A.P.2
Laaksonen, A.3
Nordenskiold, L.4
-
20
-
-
1842683168
-
Molecular dynamics simulation study of oriented polyamine- and Na-DNA: sequence specific interactions and effects on DNA structure
-
Korolev N., Lyubartsev A.P., Laaksonen A., Nordenskiold L. Molecular dynamics simulation study of oriented polyamine- and Na-DNA: sequence specific interactions and effects on DNA structure. Biopolymers 2004, 73:542-555.
-
(2004)
Biopolymers
, vol.73
, pp. 542-555
-
-
Korolev, N.1
Lyubartsev, A.P.2
Laaksonen, A.3
Nordenskiold, L.4
-
21
-
-
70350026253
-
Molecular dynamics simulations of DNA-polycation complex formation
-
Ziebarth J., Wang Y. Molecular dynamics simulations of DNA-polycation complex formation. Biophys J 2009, 97:1971-1983.
-
(2009)
Biophys J
, vol.97
, pp. 1971-1983
-
-
Ziebarth, J.1
Wang, Y.2
-
22
-
-
79960313685
-
Molecular dynamics simulations of DNA/PEI complexes: effect of PEI branching and protonation state
-
Sun C., Tang T., Uludag H., Cuervo J.E. Molecular dynamics simulations of DNA/PEI complexes: effect of PEI branching and protonation state. Biophys J 2011, 100:2754-2763.
-
(2011)
Biophys J
, vol.100
, pp. 2754-2763
-
-
Sun, C.1
Tang, T.2
Uludag, H.3
Cuervo, J.E.4
-
23
-
-
84857693358
-
Molecular dynamics simulations for complexation of DNA with 2kDa PEI reveal profound effect of PEI architecture on complexation
-
Sun C., Tang T., Uludag H. Molecular dynamics simulations for complexation of DNA with 2kDa PEI reveal profound effect of PEI architecture on complexation. JPhys Chem B 2012, 116:2405-2413.
-
(2012)
JPhys Chem B
, vol.116
, pp. 2405-2413
-
-
Sun, C.1
Tang, T.2
Uludag, H.3
-
24
-
-
84870452224
-
Targeting the blind spot of polycationic nanocarrier-based siRNA delivery
-
Zheng M., Pavan G.M., Neeb M., Schaper A.K., Danani A., Klebe G., et al. Targeting the blind spot of polycationic nanocarrier-based siRNA delivery. ACS Nano 2012, 6:9447-9454.
-
(2012)
ACS Nano
, vol.6
, pp. 9447-9454
-
-
Zheng, M.1
Pavan, G.M.2
Neeb, M.3
Schaper, A.K.4
Danani, A.5
Klebe, G.6
-
25
-
-
0346401967
-
Molecular dynamics study of a lipid-DNA complex
-
Bandyopadhyay S., Tarek M., Klein M.L. Molecular dynamics study of a lipid-DNA complex. JPhys Chem B 1999, 103:10075-10080.
-
(1999)
JPhys Chem B
, vol.103
, pp. 10075-10080
-
-
Bandyopadhyay, S.1
Tarek, M.2
Klein, M.L.3
-
26
-
-
0037307535
-
The structure of DNA within cationic lipid/DNA complexes
-
Braun C.S., Jas G.S., Choosakoonkriang S., Koe G.S., Smith J.G., Middaugh C.R. The structure of DNA within cationic lipid/DNA complexes. Biophys J 2003, 84:1114-1123.
-
(2003)
Biophys J
, vol.84
, pp. 1114-1123
-
-
Braun, C.S.1
Jas, G.S.2
Choosakoonkriang, S.3
Koe, G.S.4
Smith, J.G.5
Middaugh, C.R.6
-
27
-
-
79960707221
-
The effect of pH on PAMAM dendrimer-siRNA complexation: endosomal considerations as determined by molecular dynamics simulation
-
Ouyang D., Zhang H., Parekh H.S., Smith S.C. The effect of pH on PAMAM dendrimer-siRNA complexation: endosomal considerations as determined by molecular dynamics simulation. Biophys Chem 2011, 158:126-133.
-
(2011)
Biophys Chem
, vol.158
, pp. 126-133
-
-
Ouyang, D.1
Zhang, H.2
Parekh, H.S.3
Smith, S.C.4
-
28
-
-
77954322325
-
PAMAM dendrimers for siRNA delivery: computational and experimental insights
-
Pavan G.M., Posocco P., Tagliabue A., Maly M., Malek A., Danani A., et al. PAMAM dendrimers for siRNA delivery: computational and experimental insights. Chemistry 2010, 16:7781-7795.
-
(2010)
Chemistry
, vol.16
, pp. 7781-7795
-
-
Pavan, G.M.1
Posocco, P.2
Tagliabue, A.3
Maly, M.4
Malek, A.5
Danani, A.6
-
29
-
-
84856573502
-
Poly(amidoamine)-based dendrimer/siRNA complexation studied by computer simulations: effects of pH and generation on dendrimer structure and siRNA binding
-
Karatasos K., Posocco P., Laurini E., Pricl S. Poly(amidoamine)-based dendrimer/siRNA complexation studied by computer simulations: effects of pH and generation on dendrimer structure and siRNA binding. Macromol Biosci 2012, 12:225-240.
-
(2012)
Macromol Biosci
, vol.12
, pp. 225-240
-
-
Karatasos, K.1
Posocco, P.2
Laurini, E.3
Pricl, S.4
-
30
-
-
67650504216
-
Modeling the multivalent recognition between dendritic molecules and DNA: understanding how ligand "sacrifice" and screening can enhance binding
-
Pavan G.M., Danani A., Pricl S., Smith D.K. Modeling the multivalent recognition between dendritic molecules and DNA: understanding how ligand "sacrifice" and screening can enhance binding. JAm Chem Soc 2009, 131:9686-9694.
-
(2009)
JAm Chem Soc
, vol.131
, pp. 9686-9694
-
-
Pavan, G.M.1
Danani, A.2
Pricl, S.3
Smith, D.K.4
-
31
-
-
78651466791
-
DNA compaction by a dendrimer
-
Nandy B., Maiti P.K. DNA compaction by a dendrimer. JPhys Chem B 2011, 115:217-230.
-
(2011)
JPhys Chem B
, vol.115
, pp. 217-230
-
-
Nandy, B.1
Maiti, P.K.2
-
32
-
-
84874400663
-
Attractive hydration forces in DNA-dendrimer interactions on the nanometer scale
-
Mills M., Orr B.G., Banaszak-Holl M.M., Andricioaei I. Attractive hydration forces in DNA-dendrimer interactions on the nanometer scale. JPhys Chem B 2013, 117:973-981.
-
(2013)
JPhys Chem B
, vol.117
, pp. 973-981
-
-
Mills, M.1
Orr, B.G.2
Banaszak-Holl, M.M.3
Andricioaei, I.4
-
33
-
-
77749280012
-
Ability to adapt: different generations of PAMAM dendrimers show different behaviors in binding siRNA
-
Pavan G.M., Albertazzi L., Danani A. Ability to adapt: different generations of PAMAM dendrimers show different behaviors in binding siRNA. JPhys Chem B 2010, 114:2667-2675.
-
(2010)
JPhys Chem B
, vol.114
, pp. 2667-2675
-
-
Pavan, G.M.1
Albertazzi, L.2
Danani, A.3
-
34
-
-
78650260446
-
Molecular characterization of the interaction between siRNA and PAMAM G7 dendrimers by SAXS, ITC, and molecular dynamics simulations
-
Jensen L.B., Mortensen K., Pavan G.M., Kasimova M.R., Jensen D.K., Gadzhyeva V., et al. Molecular characterization of the interaction between siRNA and PAMAM G7 dendrimers by SAXS, ITC, and molecular dynamics simulations. Biomacromol 2010, 11:3571-3577.
-
(2010)
Biomacromol
, vol.11
, pp. 3571-3577
-
-
Jensen, L.B.1
Mortensen, K.2
Pavan, G.M.3
Kasimova, M.R.4
Jensen, D.K.5
Gadzhyeva, V.6
-
35
-
-
80051868887
-
Elucidating the molecular mechanism of PAMAM-siRNA dendriplex self-assembly: effect of dendrimer charge density
-
Jensen L.B., Pavan G.M., Kasimova M.R., Rutherford S., Danani A., Nielsen H.M., et al. Elucidating the molecular mechanism of PAMAM-siRNA dendriplex self-assembly: effect of dendrimer charge density. Int J Pharm 2011, 416:410-418.
-
(2011)
Int J Pharm
, vol.416
, pp. 410-418
-
-
Jensen, L.B.1
Pavan, G.M.2
Kasimova, M.R.3
Rutherford, S.4
Danani, A.5
Nielsen, H.M.6
-
36
-
-
77950102895
-
Computational insights into the interactions between DNA and siRNA with "rigid" and "flexible" triazine dendrimers
-
Pavan G.M., Mintzer M.A., Simanek E.E., Merkel O.M., Kissel T., Danani A. Computational insights into the interactions between DNA and siRNA with "rigid" and "flexible" triazine dendrimers. Biomacromol 2010, 11:721-730.
-
(2010)
Biomacromol
, vol.11
, pp. 721-730
-
-
Pavan, G.M.1
Mintzer, M.A.2
Simanek, E.E.3
Merkel, O.M.4
Kissel, T.5
Danani, A.6
-
37
-
-
33846164122
-
Structure and dynamics of DNA-dendrimer complexation: role of counterions, water, and base pair sequence
-
Maiti P.K., Bagchi B. Structure and dynamics of DNA-dendrimer complexation: role of counterions, water, and base pair sequence. Nano Lett 2006, 6:2478-2485.
-
(2006)
Nano Lett
, vol.6
, pp. 2478-2485
-
-
Maiti, P.K.1
Bagchi, B.2
-
38
-
-
77954694522
-
Structure, dynamics, and energetics of siRNA-cationic vector complexation: a molecular dynamics study
-
Ouyang D., Zhang H., Herten D.P., Parekh H.S., Smith S.C. Structure, dynamics, and energetics of siRNA-cationic vector complexation: a molecular dynamics study. JPhys Chem B 2010, 114:9220-9230.
-
(2010)
JPhys Chem B
, vol.114
, pp. 9220-9230
-
-
Ouyang, D.1
Zhang, H.2
Herten, D.P.3
Parekh, H.S.4
Smith, S.C.5
-
39
-
-
77957792353
-
Complexation of siRNA with dendrimer: a molecular modeling approach
-
Vasumathi V., Maiti P.K. Complexation of siRNA with dendrimer: a molecular modeling approach. Macromol 2010, 43:8264-8274.
-
(2010)
Macromol
, vol.43
, pp. 8264-8274
-
-
Vasumathi, V.1
Maiti, P.K.2
-
40
-
-
81255184847
-
Understanding the effect of polylysine architecture on DNA binding using molecular dynamics simulations
-
Elder R.M., Emrick T., Jayaraman A. Understanding the effect of polylysine architecture on DNA binding using molecular dynamics simulations. Biomacromol 2011, 12:3870-3879.
-
(2011)
Biomacromol
, vol.12
, pp. 3870-3879
-
-
Elder, R.M.1
Emrick, T.2
Jayaraman, A.3
-
41
-
-
77954713630
-
Structure and dynamics of multiple cationic vectors-siRNA complexation by all-atomic molecular dynamics simulations
-
Ouyang D., Zhang H., Parekh H.S., Smith S.C. Structure and dynamics of multiple cationic vectors-siRNA complexation by all-atomic molecular dynamics simulations. JPhys Chem B 2010, 114:9231-9237.
-
(2010)
JPhys Chem B
, vol.114
, pp. 9231-9237
-
-
Ouyang, D.1
Zhang, H.2
Parekh, H.S.3
Smith, S.C.4
-
42
-
-
77950835322
-
Quantifying the effect of surface ligands on dendron-DNA interactions: insights into multivalency through a combined experimental and theoretical approach
-
Jones S.P., Pavan G.M., Danani A., Pricl S., Smith D.K. Quantifying the effect of surface ligands on dendron-DNA interactions: insights into multivalency through a combined experimental and theoretical approach. Chemistry 2010, 16:4519-4532.
-
(2010)
Chemistry
, vol.16
, pp. 4519-4532
-
-
Jones, S.P.1
Pavan, G.M.2
Danani, A.3
Pricl, S.4
Smith, D.K.5
-
43
-
-
77951821505
-
Computational approach for understanding the interactions of UV-degradable dendrons with DNA and siRNA
-
Pavan G.M., Kostiainen M.A., Danani A. Computational approach for understanding the interactions of UV-degradable dendrons with DNA and siRNA. JPhys Chem B 2010, 114:5686-5693.
-
(2010)
JPhys Chem B
, vol.114
, pp. 5686-5693
-
-
Pavan, G.M.1
Kostiainen, M.A.2
Danani, A.3
-
44
-
-
79955152065
-
Less is more - multiscale modelling of self-assembling multivalency and its impact on DNA binding and gene delivery
-
Posocco P., Pricl S., Jones S., Barnard A., Smith D.K. Less is more - multiscale modelling of self-assembling multivalency and its impact on DNA binding and gene delivery. Chem Sci 2010, 1:393-404.
-
(2010)
Chem Sci
, vol.1
, pp. 393-404
-
-
Posocco, P.1
Pricl, S.2
Jones, S.3
Barnard, A.4
Smith, D.K.5
-
45
-
-
0035136714
-
Simple simulations of DNA condensation
-
Stevens M.J. Simple simulations of DNA condensation. Biophys J 2001, 80:130-139.
-
(2001)
Biophys J
, vol.80
, pp. 130-139
-
-
Stevens, M.J.1
-
46
-
-
0242321243
-
Modeling of DNA compaction by polycations
-
Dias R.S., Pais A.A.C.C., Miguel M.G., Lindman B. Modeling of DNA compaction by polycations. JChem Phys 2003, 119:8150-8157.
-
(2003)
JChem Phys
, vol.119
, pp. 8150-8157
-
-
Dias, R.S.1
Pais, A.A.C.C.2
Miguel, M.G.3
Lindman, B.4
-
47
-
-
77952505550
-
Coarse-grained molecular dynamics simulations of DNA condensation by block copolymer and formation of core-corona structures
-
Ziebarth J., Wang Y. Coarse-grained molecular dynamics simulations of DNA condensation by block copolymer and formation of core-corona structures. JPhys Chem B 2010, 114:6225-6232.
-
(2010)
JPhys Chem B
, vol.114
, pp. 6225-6232
-
-
Ziebarth, J.1
Wang, Y.2
-
48
-
-
34249041190
-
Inter-DNA electrostatics from explicit solvent molecular dynamics simulations
-
Savelyev A., Papoian G.A. Inter-DNA electrostatics from explicit solvent molecular dynamics simulations. JAm Chem Soc 2007, 129:6060-6061.
-
(2007)
JAm Chem Soc
, vol.129
, pp. 6060-6061
-
-
Savelyev, A.1
Papoian, G.A.2
-
49
-
-
41149115685
-
Molecular dynamics simulation of multivalent-ion mediated attraction between DNA molecules
-
Dai L., Mu Y., Nordenskiold L., van der Maarel J.R. Molecular dynamics simulation of multivalent-ion mediated attraction between DNA molecules. Phys Rev Lett 2008, 100:118301.
-
(2008)
Phys Rev Lett
, vol.100
, pp. 118301
-
-
Dai, L.1
Mu, Y.2
Nordenskiold, L.3
van der Maarel, J.R.4
-
50
-
-
84872278903
-
Potential of mean force of polyethylenimine-mediated DNA attraction
-
Bagai S., Sun C., Tang T. Potential of mean force of polyethylenimine-mediated DNA attraction. JPhys Chem B 2013, 117:49-56.
-
(2013)
JPhys Chem B
, vol.117
, pp. 49-56
-
-
Bagai, S.1
Sun, C.2
Tang, T.3
-
51
-
-
80053964044
-
Molecular dynamics simulations of PEI mediated DNA aggregation
-
Sun C., Tang T., Uludag H. Molecular dynamics simulations of PEI mediated DNA aggregation. Biomacromol 2011, 12:3698-3707.
-
(2011)
Biomacromol
, vol.12
, pp. 3698-3707
-
-
Sun, C.1
Tang, T.2
Uludag, H.3
-
52
-
-
84866137983
-
Probing the effects of lipid substitution on polycation mediated DNA aggregation: a molecular dynamics simulations study
-
Sun C., Tang T., Uludag H. Probing the effects of lipid substitution on polycation mediated DNA aggregation: a molecular dynamics simulations study. Biomacromol 2012, 13:2982-2988.
-
(2012)
Biomacromol
, vol.13
, pp. 2982-2988
-
-
Sun, C.1
Tang, T.2
Uludag, H.3
-
53
-
-
84873091256
-
Amolecular dynamics simulation study on the effect of lipid substitution on polyethylenimine mediated siRNA complexation
-
Sun C., Tang T., Uludag H. Amolecular dynamics simulation study on the effect of lipid substitution on polyethylenimine mediated siRNA complexation. Biomaterials 2013, 34:2822-2833.
-
(2013)
Biomaterials
, vol.34
, pp. 2822-2833
-
-
Sun, C.1
Tang, T.2
Uludag, H.3
-
54
-
-
32644460458
-
Mesoscale computer modeling of lipid-DNA complexes for gene therapy
-
Farago O., Gronbech-Jensen N., Pincus P. Mesoscale computer modeling of lipid-DNA complexes for gene therapy. Phys Rev Lett 2006, 96:018102.
-
(2006)
Phys Rev Lett
, vol.96
, pp. 018102
-
-
Farago, O.1
Gronbech-Jensen, N.2
Pincus, P.3
-
55
-
-
68049096292
-
Simulation of self-assembly of cationic lipids and DNA into structured complexes
-
Farago O., Gronbech-Jensen N. Simulation of self-assembly of cationic lipids and DNA into structured complexes. JAm Chem Soc 2009, 131:2875-2881.
-
(2009)
JAm Chem Soc
, vol.131
, pp. 2875-2881
-
-
Farago, O.1
Gronbech-Jensen, N.2
-
56
-
-
65349190502
-
Dendrimers as synthetic gene vectors: cell membrane attachment
-
Voulgarakis N.K., Rasmussen K.O., Welch P.M. Dendrimers as synthetic gene vectors: cell membrane attachment. JChem Phys 2009, 130:155101.
-
(2009)
JChem Phys
, vol.130
, pp. 155101
-
-
Voulgarakis, N.K.1
Rasmussen, K.O.2
Welch, P.M.3
-
57
-
-
84881667139
-
Design maps for cellular uptake of gene nanovectors by computer simulation
-
Ding H.M., Ma Y.Q. Design maps for cellular uptake of gene nanovectors by computer simulation. Biomaterials 2013, 34:8401-8407.
-
(2013)
Biomaterials
, vol.34
, pp. 8401-8407
-
-
Ding, H.M.1
Ma, Y.Q.2
-
58
-
-
33846796031
-
Understanding intracellular transport processes pertinent to synthetic gene delivery via stochastic simulations and sensitivity analyses
-
Dinh A.T., Pangarkar C., Theofanous T., Mitragotri S. Understanding intracellular transport processes pertinent to synthetic gene delivery via stochastic simulations and sensitivity analyses. Biophys J 2007, 92:831-846.
-
(2007)
Biophys J
, vol.92
, pp. 831-846
-
-
Dinh, A.T.1
Pangarkar, C.2
Theofanous, T.3
Mitragotri, S.4
-
59
-
-
84867452391
-
Enhanced condensation and facilitated release of DNA using mixed cationic agents: a combined experimental and Monte Carlo study
-
Jorge A.F., Dias R.S., Pais A.A. Enhanced condensation and facilitated release of DNA using mixed cationic agents: a combined experimental and Monte Carlo study. Biomacromol 2012, 13:3151-3161.
-
(2012)
Biomacromol
, vol.13
, pp. 3151-3161
-
-
Jorge, A.F.1
Dias, R.S.2
Pais, A.A.3
-
60
-
-
0031860769
-
Size, diffusibility and transfection performance of linear PEI/DNA complexes in the mouse central nervous system
-
Goula D., Remy J.S., Erbacher P., Wasowicz M., Levi G., Abdallah B., et al. Size, diffusibility and transfection performance of linear PEI/DNA complexes in the mouse central nervous system. Gene Ther 1998, 5:712-717.
-
(1998)
Gene Ther
, vol.5
, pp. 712-717
-
-
Goula, D.1
Remy, J.S.2
Erbacher, P.3
Wasowicz, M.4
Levi, G.5
Abdallah, B.6
-
61
-
-
84885642089
-
Characterization of conformation and interaction of gene delivery vector polyethylenimine with phospholipid bilayer at different protonation state
-
Choudhury C.K., Kumar A., Roy S. Characterization of conformation and interaction of gene delivery vector polyethylenimine with phospholipid bilayer at different protonation state. Biomacromolecules 2013, 14:3759-3768.
-
(2013)
Biomacromolecules
, vol.14
, pp. 3759-3768
-
-
Choudhury, C.K.1
Kumar, A.2
Roy, S.3
-
62
-
-
22244452943
-
Membrane electroporation: a molecular dynamics simulation
-
Tarek M. Membrane electroporation: a molecular dynamics simulation. Biophys J 2005, 88:4045-4053.
-
(2005)
Biophys J
, vol.88
, pp. 4045-4053
-
-
Tarek, M.1
-
63
-
-
84865644203
-
Transport of siRNA through lipid membranes driven by nanosecond electric pulses: an experimental and computational study
-
Breton M., Delemotte L., Silve A., Mir L.M., Tarek M. Transport of siRNA through lipid membranes driven by nanosecond electric pulses: an experimental and computational study. JAm Chem Soc 2012, 134:13938-13941.
-
(2012)
JAm Chem Soc
, vol.134
, pp. 13938-13941
-
-
Breton, M.1
Delemotte, L.2
Silve, A.3
Mir, L.M.4
Tarek, M.5
-
64
-
-
23244440384
-
Constant pH molecular dynamics with proton tautomerism
-
Khandogin J., Brooks C.L. Constant pH molecular dynamics with proton tautomerism. Biophys J 2005, 89:141-157.
-
(2005)
Biophys J
, vol.89
, pp. 141-157
-
-
Khandogin, J.1
Brooks, C.L.2
-
65
-
-
0036732086
-
Constant-pH molecular dynamics using stochastic titration
-
Baptista A.M., Teixeira V.H., Soares C.M. Constant-pH molecular dynamics using stochastic titration. JChem Phys 2002, 117:4184-4200.
-
(2002)
JChem Phys
, vol.117
, pp. 4184-4200
-
-
Baptista, A.M.1
Teixeira, V.H.2
Soares, C.M.3
-
66
-
-
9244223045
-
Constant pH molecular dynamics in generalized born implicit solvent
-
Mongan J., Case D.A., McCammon J.A. Constant pH molecular dynamics in generalized born implicit solvent. JComput Chem 2004, 25:2038-2048.
-
(2004)
JComput Chem
, vol.25
, pp. 2038-2048
-
-
Mongan, J.1
Case, D.A.2
McCammon, J.A.3
-
67
-
-
80051643867
-
Continuous constant pH molecular dynamics in explicit solvent with pH-based replica exchange
-
Wallace J.A., Shen J.K. Continuous constant pH molecular dynamics in explicit solvent with pH-based replica exchange. JChem Theory Comput 2011, 7:2617-2629.
-
(2011)
JChem Theory Comput
, vol.7
, pp. 2617-2629
-
-
Wallace, J.A.1
Shen, J.K.2
-
68
-
-
84855710487
-
Constant pH molecular dynamics simulations of nucleic acids in explicit solvent
-
Goh G.B., Knight J.L., Brooks C.L. Constant pH molecular dynamics simulations of nucleic acids in explicit solvent. JChem Theory Comput 2012, 8:36-46.
-
(2012)
JChem Theory Comput
, vol.8
, pp. 36-46
-
-
Goh, G.B.1
Knight, J.L.2
Brooks, C.L.3
-
69
-
-
79959283736
-
Constant pH molecular dynamics in explicit solvent with lambda-dynamics
-
Donnini S., Tegeler F., Groenhof G., Grubmuller H. Constant pH molecular dynamics in explicit solvent with lambda-dynamics. JChem Theory Comput 2011, 7:1962-1978.
-
(2011)
JChem Theory Comput
, vol.7
, pp. 1962-1978
-
-
Donnini, S.1
Tegeler, F.2
Groenhof, G.3
Grubmuller, H.4
-
70
-
-
0141995069
-
The nuclear pore complex: nucleocytoplasmic transport and beyond
-
Fahrenkrog B., Aebi U. The nuclear pore complex: nucleocytoplasmic transport and beyond. Nat Rev Mol Cell Biol 2003, 4:757-766.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 757-766
-
-
Fahrenkrog, B.1
Aebi, U.2
-
71
-
-
61449201281
-
Transport-related structures and processes of the nuclear pore complex studied through molecular dynamics
-
Miao L., Schulten K. Transport-related structures and processes of the nuclear pore complex studied through molecular dynamics. Structure 2009, 17:449-459.
-
(2009)
Structure
, vol.17
, pp. 449-459
-
-
Miao, L.1
Schulten, K.2
-
72
-
-
83655190545
-
Receptor-mediated endocytosis of nanoparticles of various shapes
-
Vacha R., Martinez-Veracoechea F.J., Frenkel D. Receptor-mediated endocytosis of nanoparticles of various shapes. Nano Lett 2011, 11:5391-5395.
-
(2011)
Nano Lett
, vol.11
, pp. 5391-5395
-
-
Vacha, R.1
Martinez-Veracoechea, F.J.2
Frenkel, D.3
-
73
-
-
84861339009
-
Role of physicochemical properties of coating ligands in receptor-mediated endocytosis of nanoparticles
-
Ding H.M., Ma Y.Q. Role of physicochemical properties of coating ligands in receptor-mediated endocytosis of nanoparticles. Biomaterials 2012, 33:5798-5802.
-
(2012)
Biomaterials
, vol.33
, pp. 5798-5802
-
-
Ding, H.M.1
Ma, Y.Q.2
-
74
-
-
0022588467
-
Similarity of protein encoded by the human C-Erb-B-2 gene to epidermal growth-factor receptor
-
Yamamoto T., Ikawa S., Akiyama T., Semba K., Nomura N., Miyajima N., et al. Similarity of protein encoded by the human C-Erb-B-2 gene to epidermal growth-factor receptor. Nature 1986, 319:230-234.
-
(1986)
Nature
, vol.319
, pp. 230-234
-
-
Yamamoto, T.1
Ikawa, S.2
Akiyama, T.3
Semba, K.4
Nomura, N.5
Miyajima, N.6
-
75
-
-
0034600849
-
The ErbB signaling network: receptor heterodimerization in development and cancer
-
Olayioye M.A., Neve R.M., Lane H.A., Hynes N.E. The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J 2000, 19:3159-3167.
-
(2000)
EMBO J
, vol.19
, pp. 3159-3167
-
-
Olayioye, M.A.1
Neve, R.M.2
Lane, H.A.3
Hynes, N.E.4
-
76
-
-
37049183697
-
Human-breast cancer - correlation of relapse and survival with amplification of the Her-2 Neu oncogene
-
Slamon D.J., Clark G.M., Wong S.G., Levin W.J., Ullrich A., Mcguire W.L. Human-breast cancer - correlation of relapse and survival with amplification of the Her-2 Neu oncogene. Science 1987, 235:177-182.
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
Levin, W.J.4
Ullrich, A.5
Mcguire, W.L.6
-
77
-
-
0021363327
-
Growth-inhibition of human-tumor cells in athymic mice by anti-epidermal growth-factor receptor monoclonal antibodies
-
Masui H., Kawamoto T., Sato J.D., Wolf B., Sato G., Mendelsohn J. Growth-inhibition of human-tumor cells in athymic mice by anti-epidermal growth-factor receptor monoclonal antibodies. Cancer Res 1984, 44:1002-1007.
-
(1984)
Cancer Res
, vol.44
, pp. 1002-1007
-
-
Masui, H.1
Kawamoto, T.2
Sato, J.D.3
Wolf, B.4
Sato, G.5
Mendelsohn, J.6
-
78
-
-
66149084032
-
Atomistic insights into regulatory mechanisms of the HER2 tyrosine kinase domain: a molecular dynamics study
-
Telesco S.E., Radhakrishnan R. Atomistic insights into regulatory mechanisms of the HER2 tyrosine kinase domain: a molecular dynamics study. Biophys J 2009, 96:2321-2334.
-
(2009)
Biophys J
, vol.96
, pp. 2321-2334
-
-
Telesco, S.E.1
Radhakrishnan, R.2
-
79
-
-
0347285239
-
Structural analysis of the epitopes on erbB2 interacted with inhibitory or non-inhibitory monoclonal antibodies
-
Wang J.N., Feng J.N., Yu M., Xu M., Shi M., Zhou T., et al. Structural analysis of the epitopes on erbB2 interacted with inhibitory or non-inhibitory monoclonal antibodies. Mol Immunol 2003, 40:963-969.
-
(2003)
Mol Immunol
, vol.40
, pp. 963-969
-
-
Wang, J.N.1
Feng, J.N.2
Yu, M.3
Xu, M.4
Shi, M.5
Zhou, T.6
-
80
-
-
83155183294
-
Identifying HER2 inhibitors from natural products database
-
Yang S.C., Chang S.S., Chen C.Y. Identifying HER2 inhibitors from natural products database. PLoS One 2011, 6:e28793.
-
(2011)
PLoS One
, vol.6
-
-
Yang, S.C.1
Chang, S.S.2
Chen, C.Y.3
|