Understanding the effect of polylysine architecture on DNA binding using molecular dynamics simulations

Biomacromolecules

Volumn 12, Issue 11, 2011, Pages 3870-3879

  Elder, Robert M ^a   Emrick, Todd ^b   Jayaraman, Arthi ^a  

^a UCB 450   (United States)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMISTIC MOLECULAR DYNAMICS SIMULATIONS; BINDING FREE ENERGY; DNA TRANSFECTION; DNA-BINDING; ENTROPIC CONTRIBUTIONS; MOLECULAR DYNAMICS SIMULATIONS; POLY-L-LYSINE; POLYCATIONS; POLYLYSINE; THERMODYNAMIC EFFECT; TRANSFECTION EFFICIENCY;

AMINO ACIDS; ARCHITECTURE; BINDING ENERGY; DNA; DYNAMICS; FREE ENERGY; MOLECULAR DYNAMICS;

GRAFTING (CHEMICAL);

AMINE; DNA; POLYCATION; POLYLYSINE;

ARTICLE; DNA BINDING; ENTROPY; HYDROPHOBICITY; MOLECULAR DYNAMICS; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN STRUCTURE;

ALGORITHMS; DNA; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MOLECULAR DYNAMICS SIMULATION; NUCLEIC ACID CONFORMATION; POLYLYSINE; PROTEIN BINDING; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

EID: 81255184847     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm201113y     Document Type: Article

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