A molecular dynamics simulation study on the effect of lipid substitution on polyethylenimine mediated siRNA complexation

Biomaterials

Volumn 34, Issue 11, 2013, Pages 2822-2833

  Sun, Chongbo ^a   Tang, Tian ^a   Uludag, Hasan ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Gene delivery; Lipid; Molecular dynamics; Polyethylenimine; Polyplex; SiRNA

Indexed keywords

ATOMISTIC LEVELS; GENE DELIVERY; LIPID MODIFICATIONS; MOLECULAR DYNAMICS SIMULATIONS; NONVIRAL; POLYCATIONS; POLYETHYLENIMINES; POLYIONS; POLYPLEXES; REVERSE EFFECTS; SIRNA; SIRNA DELIVERY; SMALL INTERFERING RNA (SIRNA); STERIC HINDRANCES; SYSTEMATIC EVALUATION;

GENE TRANSFER; LIPIDS; RNA;

MOLECULAR DYNAMICS;

LIPID; POLYCATION; POLYETHYLENEIMINE; SMALL INTERFERING RNA;

AMINO ACID SUBSTITUTION; ARTICLE; ATOM; COMPLEX FORMATION; LIPID SUBSTITUTION; MOLECULAR DYNAMICS; PRIORITY JOURNAL; RNA STRUCTURE;

GENE TRANSFER TECHNIQUES; LIPIDS; MOLECULAR DYNAMICS SIMULATION; POLYAMINES; POLYETHYLENEIMINE; RNA, SMALL INTERFERING;

EID: 84873091256     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.01.011     Document Type: Article

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