Elucidating the molecular mechanism of PAMAM-siRNA dendriplex self-assembly: Effect of dendrimer charge density

International Journal of Pharmaceutics

Volumn 416, Issue 2, 2011, Pages 410-418

  Jensen, Linda B ^a   Pavan, Giovanni M ^b   Kasimova, Marina R ^a   Rutherford, Sandra ^c   Danani, Andrea ^b   Nielsen, Hanne M ^a   Foged, Camilla ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF APPLIED SCIENCES AND ARTS OF SOUTHERN SWITZERLAND   (Switzerland)

^c Molecular Profiles Ltd   (United Kingdom)

Author keywords

Dendriplex; Isothermal titration calorimetry; Molecular dynamics simulations; Nanoparticle tracking analysis; PAMAM dendrimers; siRNA

Indexed keywords

DENDRIMER; POLYAMIDOAMINE; SMALL INTERFERING RNA;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; ENTROPY; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; PRIORITY JOURNAL; RNA BINDING; STATIC ELECTRICITY; SURFACE CHARGE;

CALORIMETRY; DENDRIMERS; LIGHT; MOLECULAR DYNAMICS SIMULATION; NANOPARTICLES; PARTICLE SIZE; RNA, SMALL INTERFERING; SCATTERING, RADIATION; STATIC ELECTRICITY; THERMODYNAMICS;

EID: 80051868887     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.03.015     Document Type: Article

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