Amino acid misincorporation in recombinant biopharmaceutical products

Current Opinion in Biotechnology

Volumn 30, Issue , 2014, Pages 45-50

  Harris, Robert P ^a   Kilby, Peter M ^a  

^a JEALOTT S HILL INTERNATIONAL RESEARCH CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; MAMMALS;

AMINO ACID MISINCORPORATION; BIOPHARMACEUTICAL PRODUCTS; BIOTHERAPEUTICS; GENE SEQUENCES; MAMMALIAN HOSTS; MULTIPLE SPECIES; PRODUCTION ENVIRONMENTS; THERAPEUTIC PRODUCTS;

PROTEINS;

EPIDERMAL GROWTH FACTOR; AMINO ACID; RECOMBINANT PROTEIN; CODON;

AMINO ACID METABOLISM; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CHO CELL LINE; DNA SEQUENCE; DOWNSTREAM PROCESSING; GENETIC TRANSCRIPTION; HUMAN; KWASHIORKOR; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; REVIEW; RIBOSOMAL FRAMESHIFTING; RNA TRANSLATION; STOP CODON; AMINO ACID ANALYSIS; BASE MISPAIRING; FERMENTATION OPTIMIZATION; GENE EXPRESSION SYSTEM; NONHUMAN; PROCESS DEVELOPMENT; PROTEIN MODIFICATION; RNA EDITING; RNA TRANSCRIPTION; UPREGULATION; ANIMAL; CHEMISTRY; CODON;

AMINO ACID SUBSTITUTION; AMINO ACIDS; ANIMALS; CODON; HUMANS; PROTEIN BIOSYNTHESIS; RECOMBINANT PROTEINS; TRANSCRIPTION, GENETIC;

EID: 84902077768     PISSN: 09581669     EISSN: 18790429     Source Type: Journal    
DOI: 10.1016/j.copbio.2014.05.003     Document Type: Review

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