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Volumn 81, Issue 22, 2009, Pages 9282-9290
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Identification of codon-specific serine to asparagine mistranslation in recombinant monoclonal antibodies by high-resolution mass spectrometry
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Author keywords
[No Author keywords available]
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Indexed keywords
ASPARAGINE RESIDUE;
CHINESE HAMSTER OVARY CELLS;
DYNAMIC RANGE;
ERROR RATE;
HIGH RESOLUTION MASS SPECTROMETRY;
HIGH SENSITIVITY;
IN-VIVO;
LOW LEVEL;
MAMMALIAN CELL LINES;
MAP ANALYSIS;
PROTEIN BIOSYNTHESIS;
PROTEIN VARIANTS;
RECOMBINANT MONOCLONAL ANTIBODY;
RECOMBINANT PROTEIN;
REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
TANDEM MASS SPECTROMETRY;
AMINES;
BIOCHEMISTRY;
CELL CULTURE;
CHROMATOGRAPHIC ANALYSIS;
HIGH PRESSURE LIQUID CHROMATOGRAPHY;
MAMMALS;
MASS SPECTROMETERS;
MASS SPECTROMETRY;
MONOCLONAL ANTIBODIES;
ORGANIC ACIDS;
PEPTIDES;
SURFACE PLASMON RESONANCE;
AMINO ACIDS;
AMINO ACID;
ASPARAGINE;
MONOCLONAL ANTIBODY;
RECOMBINANT PROTEIN;
SERINE;
ACCURACY;
ANALYTIC METHOD;
ANIMAL CELL;
ARTICLE;
CHO CELL;
MASS;
MASS SPECTROMETRY;
NONHUMAN;
PEPTIDE MAPPING;
PROTEIN SYNTHESIS;
PROTEIN VARIANT;
REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
SENSITIVITY AND SPECIFICITY;
ANIMALS;
ANTIBODIES, MONOCLONAL;
CHO CELLS;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
CHROMATOGRAPHY, REVERSE-PHASE;
CODON;
CRICETINAE;
CRICETULUS;
PROTEIN BIOSYNTHESIS;
RECOMBINANT PROTEINS;
SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;
TANDEM MASS SPECTROMETRY;
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EID: 70649100426
PISSN: 00032700
EISSN: None
Source Type: Journal
DOI: 10.1021/ac901541h Document Type: Article |
Times cited : (67)
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References (21)
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