Cardioprotective efficacy against reperfusion injury of EMD-87580: Comparison to ischemic postconditioning

European Journal of Pharmacology

Volumn 737, Issue , 2014, Pages 125-132

  Fantinelli, Juliana ^a   González Arbeláez, Luisa F ^a   Mosca, Susana M ^a  

^a UNIVERSIDAD NACIONAL DE LA PLATA   (Argentina)

Author keywords

Infarct size; Ischemic postconditioning; NHE 1 blockade; P GSK 3 ; Reactive oxygen species

Indexed keywords

CARDIOVASCULAR AGENT; EMD 87580; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE; GLYCOGEN SYNTHASE KINASE 3BETA; MANGANESE SUPEROXIDE DISMUTASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG; CARDIOTONIC AGENT; GROWTH FACTOR-ACTIVATABLE NA-H EXCHANGER NHE-1; GUANIDINE DERIVATIVE; N-(2-METHYL-4,5-BIS(METHYLSULFONYL)BENZOYL)GUANIDINE; SODIUM PROTON EXCHANGE PROTEIN; SULFONE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CYTOSOL; DRUG EFFICACY; HEART INFARCTION SIZE; HEART LEFT VENTRICLE DP-DT; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE ISCHEMIA; HEART PROTECTION; ISCHEMIC POSTCONDITIONING; LEFT VENTRICULAR DEVELOPED PRESSURE; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; ANIMAL; ANTAGONISTS AND INHIBITORS; COMPARATIVE STUDY; DRUG EFFECTS; DRUG THERAPY; HEART LEFT VENTRICLE FUNCTION; METABOLISM; MYOCARDIAL REPERFUSION INJURY; PATHOPHYSIOLOGY; PHOSPHORYLATION; WISTAR RAT;

ANIMALS; CARDIOTONIC AGENTS; GUANIDINES; ISCHEMIC POSTCONDITIONING; MALE; MYOCARDIAL REPERFUSION INJURY; OXIDATIVE STRESS; PHOSPHORYLATION; RATS; RATS, WISTAR; SODIUM-HYDROGEN ANTIPORTER; SULFONES; VENTRICULAR DYSFUNCTION, LEFT;

EID: 84901908344     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.05.010     Document Type: Article

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