Mitochondrial KATP channels participate in the limitation of infarct size by cariporide

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 383, Issue 6, 2011, Pages 563-571

  Nuñez, Ignacio Pérez ^a   Fantinelli, Juliana ^a   Arbeláez, Luisa F González ^a   Mosca, Susana M ^a  

^a UNIVERSIDAD NACIONAL DE LA PLATA   (Argentina)

Author keywords

Cariporide; Infarct size; Mitochondrial KATP channels; mPTP; PKC

Indexed keywords

5 HYDROXYDECANOIC ACID; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CALCIUM; CARIPORIDE; CHELERYTHRINE; DIAZOXIDE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; 5-HYDROXYDECANOIC ACID; CARDIOTONIC AGENT; CARRIER PROTEIN; DECANOIC ACID DERIVATIVE; GUANIDINE DERIVATIVE; HYDROXYACID; MITOCHONDRIAL K(ATP) CHANNEL; POTASSIUM CHANNEL; PROTEIN KINASE C; SODIUM PROTON EXCHANGE PROTEIN; SULFONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY OBSTRUCTION; HEART FUNCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; ISOLATED HEART; LEFT ANTERIOR DESCENDING CORONARY ARTERY; LIGHT SCATTERING; MITOCHONDRION; NONHUMAN; RAT; REPERFUSION; ANIMAL; DISEASE MODEL; HEART INFARCTION; METABOLISM; PATHOPHYSIOLOGY; REPERFUSION INJURY; WISTAR RAT;

ANIMALS; CALCIUM; CARDIOTONIC AGENTS; DECANOIC ACIDS; DIAZOXIDE; DISEASE MODELS, ANIMAL; GUANIDINES; HYDROXY ACIDS; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; POTASSIUM CHANNELS; PROTEIN KINASE C; RATS; RATS, WISTAR; SODIUM-HYDROGEN ANTIPORTER; SULFONES;

EID: 79959376123     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-011-0632-z     Document Type: Article

References (47)

1. DG Allen SP Cairns SE Turvey JA Lee 1993 Intracellular calcium and myocardial function during ischemia Adv Exp Med Biol 346 19 29 8184757 1:STN:280:DyaK2c3ktFSksQ%3D%3D (Pubitemid 24048710)
2. G Ambrosio JT Flaherty C Duilio I Tritto G Santoro PP Elia M Condorelli M Chiariello 1991 Oxygen radicals generated at reflow induce peroxidation of membrane lipids in reperfused hearts J Clin Invest 87 2056 2066 1645750 10.1172/JCI115236 1:CAS:528:DyaK3MXltleju7w%3D
3. 2+]i load after ischemia and improves function in intact hearts Am J Physiol Heart Circ Physiol 281 H2398 H2409 11709405 1:CAS:528: DC%2BD3MXptlKgu7g%3D
4. CP Baines CX Song YT Zheng GW Wang J Zhang OL Wang Y Guo R Bolli EM Cardwell P Ping 2003 Protein kinase C epsilon interacts with and inhibits the permeability transition pore in cardiac mitochondria Circ Res 92 8 873 880 12663490 10.1161/01.RES.0000069215.36389.8D 1:CAS:528:DC%2BD3sXjtFWqu7o%3D (Pubitemid 36542528)
5. R Bolli MO Jeroudi BS Patel CJ Hartley JI Thornby R Roberts 1989 Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog Proc Natl Acad Sci 86 4695 4699 2543984 10.1073/pnas.86.12.4695 1:CAS:528:DyaL1MXksFGjurc%3D (Pubitemid 19164616)
6. MM Bradford 1976 A rapid and sensitive for the quantitation of microgram quantitites of protein utilizing the principle of protein-dye binding Anal Biochem 72 248 254 942051 10.1016/0003-2697(76)90527-3 1:CAS:528: DyaE28XksVehtrY%3D
7. JA Buege SD Aust 1978 Microsomal lipid peroxidation Methods Enzymol 52 302 309 672633 10.1016/S0076-6879(78)52032-6 1:CAS:528:DyaE1MXltVajsw%3D%3D
8. ADT Costa KD Garlid 2008 Intramitochondrial signaling: interactions among mitoKATP, PKC, ROS, and MPT Am J Physiol Heart Circ Physiol 295 2 H874 H882 18586884 10.1152/ajpheart.01189.2007 1:CAS:528:DC%2BD1cXhtVakt7vI
9. M Crompton 1999 The mitochondrial transition pore and its role in cell death Biochem J 341 233 249 10393078 10.1042/0264-6021:3410233 1:CAS:528:DyaK1MXltFCks74%3D (Pubitemid 29373645)
10. B Das C Sarkar 2003 Mitochondrial KATP channel activation is important in the antiarrhythmic and cardioprotective effects of non-hypotensive doses of nicorandil and cromakalim during ischemia/reperfusion: a study in an intact anesthetized rabbit model Pharmacol Res 47 447 461 12741997 10.1016/S1043- 6618(02)00335-3 1:CAS:528:DC%2BD3sXjsVeisrw%3D (Pubitemid 36542923)
11. + channels are redox-sensitive pathways that control reactive oxygen species production Free Radic Biol Med 42 7 1039 1048 17349931 10.1016/j.freeradbiomed.2007.01.001 1:CAS:528:DC%2BD2sXivVantLw%3D (Pubitemid 46356894)
12. + exchanger inhibition at the onset of reperfusion decreases the myocardial infarct size: role of ROS Cardiovasc Pathol 15 4 179 184 16844548 10.1016/j.carpath.2006.04.005 1:CAS:528:DC%2BD28XntV2huro%3D (Pubitemid 44038397)
13. + exchanger-1 inhibitors decrease myocardial superoxide production via direct mitochondrial action J Appl Physiol 105 1706 1713 18801963 10.1152/japplphysiol.90616.2008 1:CAS:528:DC%2BD1MXmvFSmtA%3D%3D
14. Garciarena CD, Fantinelli JC, Caldiz CI, Chiappe de Cingolani G, Ennis IL, Pérez NG, Cingolani HE, Mosca SM (2011) Myocardial reperfusion injury: reactive oxygen species vs. NHE-1 reactivation. Cell Physiol Biochem, in press
15. DR Green G Kroemer 2004 The pathophysiology of mitochondrial cell death Science 305 626 629 15286356 10.1126/science.1099320 1:CAS:528: DC%2BD2cXmtFWqsrc%3D (Pubitemid 39006738)
16. RJ Gumina T Mizumura N Beier P Schelling JJ Schultz GJ Gross 1998 A new sodium/hydrogen exchange inhibitor, EMD 85131, limits infarct size in dogs when administered before and after coronary occlusion J Pharmacol Exp Ther 286 175 183 9655858 1:CAS:528:DyaK1cXksFChu78%3D
17. + exchange inhibition on infarct size in rabbits Am J Physiol Heart Circ Physiol 279 6 H2673 H2677 11087220 1:CAS:528:DC%2BD3cXptFSmur8%3D
18. AP Halestrap PM Kerr S Javadov KY Woodfield 1998 Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart Biochim Biophys Acta 1366 79 94 9714750 10.1016/S0005-2728(98)00122-4 1:CAS:528:DyaK1cXltFWksL0%3D (Pubitemid 28467024)
19. 2+ overload in isolated perfused rabbit heart Circulation 89 2787 2798 8205693 1:CAS:528:DyaK2cXlvFGgurk%3D
20. + exchange inhibitor, on the ion transport of myocardial mitochondria Mol Cell Biochem 219 83 90 11354258 10.1023/A:1011019010140 1:CAS:528:DC%2BD3MXjt1amtbk%3D (Pubitemid 32331448)
21. + exchange at the beginning of reperfusion is cardioprotective in isolated, beating adult cardiomyocytes J Mol Cell Cardiol 32 1897 1907 11013133 10.1006/jmcc.2000.1222 1:CAS:528:DC%2BD3cXmvFWksrs%3D
22. S Javadov A Choi V Rajapurohitam A Zeidan AG Basnakian M Karmazyn 2008 NHE-1 inhibition-induced cardioprotection against ischaemia/reperfusion is associated with attenuation of the mitochondrial permeability transition Cardiovasc Res 77 416 424 18006455 10.1093/cvr/cvm039 1:CAS:528: DC%2BD1cXis12rsr8%3D (Pubitemid 351197641)
23. + exchange. The effect of amiloride analogues Biochim Biophys Acta 944 383 390 2846061 10.1016/0005-2736(88)90509-3 1:CAS:528:DyaL1MXltlSlsQ%3D%3D
24. + exchanger inhibitor cariporide attenuates cell injury predominantly during ischemia and not at the onset of reperfusion in porcine hearts with low residual blood flow Circulation 102 1977 1982 11034948 1:CAS:528:DC%2BD3cXnvV2qtbs%3D
25. M Lazdunski C Frelin P Vigne 1985 The sodium/hydrogen exchange system in cardiac cells: its biochemical and pharmacological properties and its role in regulating internal concentrations of sodium and internal pH J Mol Cell Cardiol 17 11 1029 1042 3001319 10.1016/S0022-2828(85)80119-X 1:CAS:528: DyaL28XkvFamsQ%3D%3D (Pubitemid 16200867)
26. EJ Lesnefsky S Moghaddas B Tandler J Kerner CL Hoppel 2001 Mitochondrial dysfunction in cardiac disease: ischemia-reperfusion, aging, and heart failure J Mol Cell Cardiol 33 1065 1089 11444914 10.1006/jmcc.2001.1378 1:CAS:528:DC%2BD3MXkvFOqtb4%3D (Pubitemid 32579276)
27. RB Mason RM Pluta S Walbridge DA Wink EH Oldfield RJ Boock 2000 Production of reactive oxygen species after reperfusion in vitro and in vivo: protective effect of nitric oxide J Neurosurg 93 99 107 10883911 10.3171/jns.2000.93.1.0099 1:CAS:528:DC%2BD3cXltFShs7c%3D (Pubitemid 30457329)
28. 2+ exchanger increase myocardial vulnerability to ischemia/reperfusion injury in rabbit hearts? Mol Cell Biochem 248 1-2 141 147 12870666 10.1023/A:1024140419688 1:CAS:528:DC%2BD3sXksFWnsb4%3D (Pubitemid 36833652)
29. L Mela S Seitz 1979 Isolation of mitochondria with emphasis on heart mitochondria from small amounts of tissue Methods Enzymol 55 39 46 459851 10.1016/0076-6879(79)55006-X 1:CAS:528:DyaE1MXlvV2hu7s%3D
30. + exchange inhibition against ischemia/reperfusion injury J Am Coll Cardiol 37 957 963 11693777 10.1016/S0735-1097(00)01183-9 1:CAS:528:DC%2BD3MXitlKitbs%3D (Pubitemid 32202469)
31. B Molavi JL Mehta 2004 Oxidative stress in cardiovascular disease: molecular basis of its deleterious effects, its detection, and therapeutic considerations Curr Opin Cardiol 19 488 493 15316458 10.1097/01.hco.0000133657. 77024.bd (Pubitemid 39222966)
32. + exchanger blockade Naunyn Schmiedeberg's Arch Pharmacol 362 7 13 10.1007/s002100000255 1:CAS:528:DC%2BD3cXlsFals70%3D (Pubitemid 30431630)
33. E Murphy C Steenbergen 2008 Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury Physiol Rev 88 581 609 18391174 10.1152/physrev.00024.2007 1:CAS:528:DC%2BD1cXls1KhsL8%3D (Pubitemid 351520088)
34. T Pain XM Yang SD Critz Y Yue A Nakano GS Liu G Heusch MV Cohen JM Downey 2000 Opening of mitochondrial KATP channels triggers the preconditioning state by generating free radicals Circ Res 87 460 466 10988237 1:CAS:528: DC%2BD3cXmvFKju7c%3D
35. + channel and protein kinase C activation Basic Res Cardiol 101 2 180 189 16450075 10.1007/s00395-006-0584-5 1:CAS:528:DC%2BD28Xjtleqsrw%3D (Pubitemid 43250810)
36. M Ruiz-Meana D Garcia-Dorado P Pina J Inserte L Agullo J Soler-Soler 2003 Cariporide preserves mitochondrial proton gradient and delays ATP depletion in cardiomyocytes during ischemic conditions Am J Physiol Heart Circ Physiol 285 H999 H1006 12915386 1:CAS:528:DC%2BD3sXnsVGntbY%3D
37. + channels by protein kinase C Circ Res 83 110 114 9670924 1:CAS:528:DyaK1cXks1Kktro%3D (Pubitemid 28322105)
38. W Scholz U Albus L Counillon H Gögelein HJ Lang W Linz A Weichert BA Schölkens 1995 Protective effects of HOE 642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusion Cardiovasc Res 29 260 268 7736504 1:CAS:528:DyaK2MXkslGhtb8%3D
39. AC Shen RB Jennings 1972 Kinetics of calcium accumulation in acute myocardial ischemic injury Am J Pathol 67 3 441 452 5033258 1:CAS:528: DyaE38Xktlags7c%3D
40. ATP channels in cardioprotection against ischemia/reperfusion injury in mice J Clin Invest 109 509 516 11854323 1:CAS:528:DC%2BD38XhsVSkt70%3D (Pubitemid 34171782)
41. 2+ dynamics at the border of the acute myocardial infarct Mol Cell Biochem 248 1-2 135 139 12870665 10.1023/A:1024188302849 1:CAS:528:DC%2BD3sXksFWnsLc%3D (Pubitemid 36833651)
42. MT Vivaldi RA Kloner FJ Schoen 1985 Triphenyltetrazolium staining of irreversible injury following coronary artery occlusion in rats Am J Pathol 121 522 530 2416222 1:STN:280:DyaL28%2FnsVClug%3D%3D (Pubitemid 16183372)
43. 2+ overload injury in rat myocardium Circ Res 84 10 1156 1165 10347090 1:CAS:528:DyaK1MXjsVygsrk%3D (Pubitemid 29244777)
44. + exchanger is critical to reperfusion damage and preconditioning in the isolated rat heart Cardiovasc Res 48 244 253 11054471 10.1016/S0008-6363(00)00166-8 1:CAS:528:DC%2BD3cXnsFWqtr4%3D
45. + exchange inhibition and mitochondrial KATP channel activation are additive in the isolated rat heart Pflugers Arch 447 3 272 279 14534792 10.1007/s00424-003-1183-z 1:CAS:528:DC%2BD3sXptleksbk%3D (Pubitemid 38186774)
46. Z-Q Zhao JS Corvera ME Halkos F Kerendi NP Wang RA Guyton J Vinten-Johansen 2003 Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning Am J Physiol Heart Circ Physiol 285 H579 H588 12860564 1:CAS:528: DC%2BD3sXmsVagsrc%3D
47. JL Zweier 1988 Measurement of superoxide-derived free radicals in the reperfused heart. Evidence for a free radical mechanism of reperfusion injury J Biol Chem 263 1353 1357 2826476 1:CAS:528:DyaL1cXpt1Ggsw%3D%3D (Pubitemid 18039938)