NHE1 inhibition improves tissue perfusion and resuscitation outcome after severe hemorrhage

Journal of Surgical Research

Volumn 181, Issue 2, 2013, Pages

  Wu, Dongmei ^a,b   Russano, Kristina ^a   Kouz, Irene ^a   Abraham, William M ^a  

^a MOUNT SINAI MEDICAL CENTER   (United States)

^b Chonbuk National University   (South Korea)

Author keywords

Hemorrhagic shock; Na+ H+ exchanger; Neurological outcomes; Oxygen transport; Resuscitation

Indexed keywords

[4 [4 (2 FUROYL) 1 PIPERAZINYL] 3 (METHYLSULFONYL)BENZOYL]GUANIDINE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CYTOKINE; INTERLEUKIN 6; SODIUM PROTON EXCHANGE PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; BLEEDING; BLOOD GAS; BLOOD OXYGEN TENSION; BRAIN BLOOD FLOW; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CYTOKINE RELEASE; EXPERIMENTAL PIG; FLUID RESUSCITATION; HEART HEMODYNAMICS; HEMORRHAGIC SHOCK; HYPOVOLEMIA; KIDNEY BLOOD FLOW; MALE; METABOLIC ACIDOSIS; NEUROLOGIC EXAMINATION; NONHUMAN; ORGAN BLOOD FLOW; OUTCOME ASSESSMENT; OXYGEN TRANSPORT; PRIORITY JOURNAL; SURVIVAL RATE; TISSUE PERFUSION;

ACIDOSIS; ANIMALS; BRAIN; BRAIN DAMAGE, CHRONIC; CEREBROVASCULAR CIRCULATION; COMBINED MODALITY THERAPY; CORONARY CIRCULATION; DOUBLE-BLIND METHOD; FLUID THERAPY; MALE; MESYLATES; PROTECTIVE AGENTS; RANDOM ALLOCATION; RENAL CIRCULATION; RESUSCITATION; SHOCK, HEMORRHAGIC; SODIUM-HYDROGEN ANTIPORTER; SWINE; TREATMENT OUTCOME;

EID: 84876413711     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2012.07.026     Document Type: Article

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