Stress hyperglycemia, insulin treatment, and innate immune cells

International Journal of Endocrinology

Volumn 2014, Issue , 2014, Pages

  Xiu, Fangming ^a   Stanojcic, Mile ^a   Diao, Li ^a   Jeschke, Marc G ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GLUCOSE; INSULIN; MACROPHAGE INFLAMMATORY PROTEIN; PROTEIN KINASE C;

CRITICAL ILLNESS; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; GLUCOSE METABOLISM; GLYCEMIC CONTROL; HUMAN; HUMAN CELL; HYPERGLYCEMIA; HYPERMETABOLISM; IMMUNE RESPONSE; IMPAIRED GLUCOSE TOLERANCE; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; INSULIN RESISTANCE; MACROPHAGE; MONOCYTE; MORBIDITY; MORTALITY; NEUTROPHIL; REVIEW; T LYMPHOCYTE;

EID: 84901773329     PISSN: 16878337     EISSN: 16878345     Source Type: Journal    
DOI: 10.1155/2014/486403     Document Type: Review

References (70)

1. Marik P. E., Bellomo R., Stress hyperglycemia: an essential survival response! Critical Care 2013 17 2, article 305 10.1186/cc12514
2. van den Berghe G., Wouters P., Weekers F., Verwaest C., Bruyninckx F., Schetz M., Vlasselaers D., Ferdinande P., Lauwers P., Bouillon R., Intensive insulin therapy in critically ill patients. The New England Journal of Medicine 2001 345 19 1359 1367 2-s2.0-0035829852 10.1056/NEJMoa011300
3. Marik P. E., Raghavan M., Stress-hyperglycemia, insulin and immunomodulation in sepsis. Intensive Care Medicine 2004 30 5 748 756 2-s2.0-2442468054 10.1007/s00134-004-2167-y (Pubitemid 38639464)
4. Mecott G. A., Al-Mousawi A. M., Gauglitz G. G., Herndon D. N., Jeschke M. G., The role of hyperglycemia in burned patients: evidence-based studies. Shock 2010 33 1 5 13 2-s2.0-73849085396 10.1097/SHK.0b013e3181af0494
5. Kerby J. D., Griffin R. L., MacLennan P., Rue L. W. III, Stress-induced hyperglycemia, not diabetic hyperglycemia, is associated with higher mortality in trauma. Annals of Surgery 2012 256 3 446 452 10.1097/SLA.0b013e3182654549
6. Zhang X., Zhang G., Zhang H., Karin M., Bai H., Cai D., Hypothalamic IKK β /NF- B and ER Stress Link Overnutrition to Energy Imbalance and Obesity. Cell 2008 135 1 61 73 2-s2.0-52949096557 10.1016/j.cell.2008.07.043
7. Xiu F., Jeschke M. G., Perturbed mononuclear phagocyte system in severely burned and septic patients. Shock 2013 40 81 88
8. Guha M., Bai W., Nadler J. L., Natarajan R., Molecular mechanisms of tumor necrosis factor α gene expression in monocytic cells via hyperglycemia-induced oxidant stress-dependent and-independent pathways. Journal of Biological Chemistry 2000 275 23 17728 17739 2-s2.0-0034625372 10.1074/jbc.275.23.17728 (Pubitemid 30430822)
9. Shanmugam N., Reddy M. A., Guha M., Natarajan R., High glucose-induced expression of proinflammatory cytokine and chemokine genes in monocytic cells. Diabetes 2003 52 5 1256 1264 2-s2.0-0042393597 10.2337/diabetes.52.5.1256 (Pubitemid 36523365)
10. Shanmugam N., Gonzalo I. T. G., Natarajan R., Molecular mechanisms of high glucose-induced cyclooxygenase-2 expression in monocytes. Diabetes 2004 53 3 795 802 2-s2.0-1442325581 10.2337/diabetes.53.3.795 (Pubitemid 38270651)
11. Devaraj S., Jialal I., Increased secretion of IP-10 from monocytes under hyperglycemia is via the TLR2 and TLR4 pathway. Cytokine 2009 47 1 6 10 2-s2.0-67449083455 10.1016/j.cyto.2009.02.004
12. Devaraj S., Venugopal S. K., Singh U., Jialal I., Hyperglycemia induces monocytic release of interleukin-6 via induction of protein kinase C- α and-β Diabetes 2005 54 1 85 91 2-s2.0-12144255424 10.2337/diabetes.54.1.85 (Pubitemid 40105098)
13. Gonzalez Y., Herrera M. T., Soldevila G., Garcia-Garcia L., Perez-Armendariz E. M., Fabian G., Bobadilla K., Guzman-Beltran S., Sada E., Torres M., High glucose concentrations induce TNF-alpha production through the down-regulation of CD33 in primary human monocytes. BMC Immunology 2012 13, article 19 2-s2.0-84859724629 10.1186/1471-2172-13-19
14. Leonidou L., Mouzaki A., Michalaki M., DeLastic A. L., Kyriazopoulou V., Bassaris H. P., Gogos C. A., Cytokine production and hospital mortality in patients with sepsis-induced stress hyperglycemia. Journal of Infection 2007 55 4 340 346 2-s2.0-34548482285 10.1016/j.jinf.2007.05.177 (Pubitemid 47376575)
15. Wei Y., Chen K., Whaley-Connell A. T., Stump C. S., Ibdah J. A., Sowers J. R., Skeletal muscle insulin resistance: role of inflammatory cytokines and reactive oxygen species. The American Journal of Physiology-Regulatory Integrative and Comparative Physiology 2008 294 3 R673 R680 2-s2.0-40449086344 10.1152/ajpregu.00561.2007 (Pubitemid 351346942)
16. Dasu M. R., Devaraj S., Zhao L., Hwang D. H., Jialal I., High glucose induces toll-like receptor expression in human monocytes Mechanism of activation. Diabetes 2008 57 11 3090 3098 2-s2.0-58149333718 10.2337/db08-0564
17. Haidet J., Cifarelli V., Trucco M., Luppi P., C-peptide reduces pro-inflammatory cytokine secretion in LPS-stimulated U937 monocytes in condition of hyperglycemia. Inflammation Research 2012 61 1 27 35 2-s2.0-84857631025 10.1007/s00011-011-0384-8
18. Qadan M., Weller E. B., Gardner S. A., Maldonado C., Fry D. E., Polk H. C. Jr., Glucose and surgical sepsis: a study of underlying immunologic mechanisms. Journal of the American College of Surgeons 2010 210 6 966 974 2-s2.0-77952551164 10.1016/j.jamcollsurg.2010.02.001
19. Turina M., Miller F. N., Tucker C. F., Polk H. C., Short-term hyperglycemia in surgical patients and a study of related cellular mechanisms. Annals of Surgery 2006 243 6 845 851 2-s2.0-33745221379 10.1097/01.sla. 0000220041.68156.67
20. Nandy D., Janardhanan R., Mukhopadhyay D., Basu A., Effect of hyperglycemia on human monocyte activation. Journal of Investigative Medicine 2011 59 4 661 667 2-s2.0-80053599750 10.231/JIM.0b013e31820ee432
21. Liu V. J., Saini A., Cohen D. J., Ooi B. S., Modulation of macrophage proliferation by hyperglycemia. Molecular and Cellular Endocrinology 1995 114 1-2 187 192 2-s2.0-0028864403 10.1016/0303-7207(95)96799-N
22. Saini A., Liu Y. J., Cohen D. J., Ooi B. S., Hyperglycemia augments macrophage growth responses to colony-stimulating factor-1. Metabolism 1996 45 9 1125 1129 2-s2.0-0029740013 10.1016/S0026-0495(96)90012-8 (Pubitemid 26300312)
23. Lamharzi N., Renard C. B., Kramer F., Pennathur S., Heinecke J. W., Chait A., Bornfeldt K. E., Hyperlipidemia in concert with hyperglycemia stimulates the proliferation of macrophages in atherosclerotic lesions: potential role of glucose-oxidized LDL. Diabetes 2004 53 12 3217 3225 2-s2.0-9444291834 10.2337/diabetes.53.12.3217 (Pubitemid 39564498)
24. Wade C. E., Hyperglycemia may alter cytokine production and phagocytosis by means other than hyperosmotic stress. Critical Care 2008 12 5, article 182 2-s2.0-68949204212
25. Yamasawa H., Nakayama M., Bando M., Sugiyama Y., Impaired inflammatory responses to multiple Toll-like receptor ligands in alveolar macrophages of streptozotocin-induced diabetic mice. Inflammation Research 2012 61 417 426 2-s2.0-84855378507 10.1007/s00011-011-0426-2
26. Sun C., Sun L., Ma H., Peng J., Zhen Y., Duan K., Liu G., Ding W., Zhao Y., The phenotype and functional alterations of macrophages in mice with hyperglycemia for long term. Journal of Cellular Physiology 2012 227 4 1670 1679 2-s2.0-84855724917 10.1002/jcp.22891
27. Kulp G. A., Tilton R. G., Herndon D. N., Jeschke M. G., Hyperglycemia exacerbates burn-induced liver inflammation via noncanonical nuclear factor-kappaB pathway activation. Molecular Medicine 2012 18 948 956
28. Alves-Filho J. C., Spiller F., Cunha F. Q., Neutrophil paralysis in sepsis. Shock 2010 34 1 15 21 2-s2.0-77955985078 10.1097/SHK.0b013e3181e7e61b
29. Turina M., Miller F. N., Tucker C., Polk H. C. Jr., Effects of hyperglycemia, hyperinsulinemia, and hyperosmolarity on neutrophil apoptosis. Surgical Infections 2006 7 2 111 121 2-s2.0-33646676959 10.1089/sur.2006.7.111 (Pubitemid 43732778)
30. Stegenga M. E., van der Crabben S. N., Blümer R. M. E., Levi M., Meijers J. C. M., Serlie M. J., Tanck M. W. T., Sauerwein H. P., Van Der Poll T., Hyperglycemia enhances coagulation and reduces neutrophil degranulation, whereas hyperinsulinemia inhibits fibrinolysis during human endotoxemia. Blood 2008 112 1 82 89 2-s2.0-47249138753 10.1182/blood-2007-11-121723
31. Alba-Loureiro T. C., Hirabara S. M., Mendonc J. R., Curi R., Pithon-Curi T. C., Diabetes causes marked changes in function and metabolism of rat neutrophils. Journal of Endocrinology 2006 188 2 295 303 2-s2.0-33244464942 10.1677/joe.1.06438 (Pubitemid 43273817)
32. McManus L. M., Bloodworth R. C., Prihoda T. J., Blodgett J. L., Pinckard R. N., Agonist-dependent failure of neutrophil function in diabetes correlates with extent of hyperglycemia. Journal of Leukocyte Biology 2001 70 3 395 404 2-s2.0-0034840002 (Pubitemid 32826127)
33. Toth B., Alexander M., Daniel T., Chaudry I. H., Hubbard W. J., Schwacha M. G., The role of γ δ T cells in the regulation of neutrophil-mediated tissue damage after thermal injury. Journal of Leukocyte Biology 2004 76 3 545 552 2-s2.0-4344668115 10.1189/jlb.0404219 (Pubitemid 39129085)
34. Daniel T., Thobe B. M., Chaudry I. H., Choudhry M. A., Hubbard W. J., Schwacha M. G., Regulation of the postburn wound inflammatory response by γ δ T-cells. Shock 2007 28 3 278 283 2-s2.0-34548016986 10.1097/shk.0b013e318034264c (Pubitemid 47282018)
35. Taylor K. R., Mills R. E., Costanzo A. E., Jameson J. M., γ δ T cells are reduced and rendered unresponsive by hyperglycemia and chronic TNF α in mouse models of obesity and metabolic disease. PLoS ONE 2010 5 7 2-s2.0-77955363489 10.1371/journal.pone.0011422 e11422
36. Gyurko R., Siqueira C. C., Caldon N., Gao L., Kantarci A., Van Dyke T. E., Chronic hyperglycemia predisposes to exaggerated inflammatory response and leukocyte dysfunction in Akita mice. Journal of Immunology 2006 177 10 7250 7256 2-s2.0-33750808412 (Pubitemid 44715094)
37. De La Rosa G., Vasquez E. M., Quintero A. M., The potential impact of admission insulin levels on patient outcome in the intensive care unit. Journal of Trauma and Acute Care Surgery 2013 74 270 275
38. Jeschke M. G., Clinical review: glucose control in severely burned patients-current best practice. Critical Care 2013 17, article 232
39. Deng H. P., Chai J. K., The effects and mechanisms of insulin on systemic inflammatory response and immune cells in severe trauma, burn injury, and sepsis. International Immunopharmacology 2009 9 11 1251 1259 2-s2.0-70249118870 10.1016/j.intimp.2009.07.009
40. Weekers F., Giulietti A. P., Michalaki M., Coopmans W., van Herck E., Mathieu C., van den Berghe G., Metabolic, endocrine, and immune effects of stress hyperglycemia in a rabbit model of prolonged critical illness. Endocrinology 2003 144 12 5329 5338 2-s2.0-0345257106 10.1210/en.2003-0697 (Pubitemid 37476061)
41. Hartell N. A., Archer H. E., Bailey C. J., Insulin-stimulated endothelial nitric oxide release is calcium independent and mediated via protein kinase B. Biochemical Pharmacology 2005 69 5 781 790 2-s2.0-13844296424 10.1016/j.bcp.2004.11.022 (Pubitemid 40248620)
42. Sarigianni M., Bekiari E., Tsapas A., Topouridou K., Kaloyianni M., Koliakos G., Paletas K., Effect of glucose and insulin on oxidized low-density lipoprotein phagocytosis by human monocytes: a pilot study. Angiology 2011 62 2 163 166 2-s2.0-78651398059 10.1177/0003319710375088
43. Dimitriadis G., Maratou E., Boutati E., Psarra K., Papasteriades C., Raptis S. A., Evaluation of glucose transport and its regulation by insulin in human monocytes using flow cytometry. Cytometry Part A 2005 64 1 27 33 2-s2.0-14644417238 10.1002/cyto.a.20108 (Pubitemid 40315705)
44. Wurm S., Neumeier M., Weigert J., Wanninger J., Gerl M., Gindner A., Schäffler A., Aslanidis C., Schölmerich J., Buechler C., Insulin induces monocytic CXCL8 secretion by the mitogenic signalling pathway. Cytokine 2008 44 1 185 190 2-s2.0-52949153266 10.1016/j.cyto.2008.08.003
45. Bunn R. C., Cockrell G. E., Ou Y., Thrailkill K. M., Lumpkin C. K. Jr., Fowlkes J. L., Palmitate and insulin synergistically induce IL-6 expression in human monocytes. Cardiovascular Diabetology 2010 9, article 73 2-s2.0-78049408569 10.1186/1475-2840-9-73
46. Fortuño A., San José G., Moreno M. U., Beloqui O., Díez J., Zalba G., Phagocytic NADPH oxidase overactivity underlies oxidative stress in metabolic syndrome. Diabetes 2006 55 1 209 215 2-s2.0-33644768153 10.2337/diabetes.55.1.209 (Pubitemid 43343317)
47. Gerrits A. J., Koekman C. A., Yildirim C., Nieuwland R., Akkerman J. W. N., Insulin inhibits tissue factor expression in monocytes. Journal of Thrombosis and Haemostasis 2009 7 1 198 205 2-s2.0-57749170252 10.1111/j.1538-7836.2008.03206.x
48. Cuschieri J., Bulger E., Grinsell R., Garcia I., Maier R. V., Insulin regulates macrophage activation through activin A1. Shock 2008 29 2 285 290 2-s2.0-38349105018 10.1097/shk.0b013e318123e4d0
49. Yoon J., Subramanian S., Ding Y., Wang S., Goodspeed L., Sullivan B., Kim J., O'Brien K. D., Chait A., Chronic insulin therapy reduces adipose tissue macrophage content in LDL-receptor-deficient mice. Diabetologia 2011 54 5 1252 1260 2-s2.0-79954627979 10.1007/s00125-011-2055-2
50. Iida K. T., Suzuki H., Sone H., Shimano H., Toyoshima H., Yatoh S., Asano T., Okuda Y., Yamada N., Insulin inhibits apoptosis of macrophage cell line, THP-1 cells, via phosphatidylinositol-3-kinase-dependent pathway. Arteriosclerosis, Thrombosis, and Vascular Biology 2002 22 3 380 386 2-s2.0-0036120714 10.1161/hq0302.105272 (Pubitemid 34218742)
51. Leffler M., Hrach T., Stuerzl M., Horch R. E., Herndon D. N., Jeschke M. G., Insulin attenuates apoptosis and exerts anti-inflammatory effects in endotoxemic human macrophages. Journal of Surgical Research 2007 143 2 398 406 2-s2.0-36048994012 10.1016/j.jss.2007.01.030 (Pubitemid 350101570)
52. Park Y. M., RK S., AM J., Silverstein R. L., Insulin promotes macrophage foam cell formation: potential implications in diabetes-related atherosclerosis. Laboratory Investigation 2012 92 1171 1180 10.1038/labinvest.2012.74
53. Sano H., Higashi T., Matsumoto K., Melkko J., Jinnouchi Y., Ikeda K., Ebina Y., Makino H., Smedsrød B., Horiuchi S., Insulin enhances macrophage scavenger receptor-mediated endocytic uptake of advanced glycation end products. Journal of Biological Chemistry 1998 273 15 8630 8637 2-s2.0-0032502763 10.1074/jbc.273.15.8630 (Pubitemid 28176138)
54. Ceschin D. G., Sánchez M. C., Chiabrando G. A., Insulin induces the low density lipoprotein receptor-related protein 1 (LRP1) degradation by the proteasomal system in J774 macrophage-derived cells. Journal of Cellular Biochemistry 2009 106 3 372 380 2-s2.0-62649120101 10.1002/jcb.22014
55. Wu H., Chen Y., Winnall W. R., Phillips D. J., Hedger M. P., Regulation of activin A release from murine bone marrow-derived neutrophil precursors by tumour necrosis factor-alpha and insulin. Cytokine 2013 61 199 204
56. Walrand S., Guillet C., Boirie Y., Vasson M.-P., In vivo evidences that insulin regulates human polymorphonuclear neutrophil functions. Journal of Leukocyte Biology 2004 76 6 1104 1110 2-s2.0-10044275561 10.1189/jlb.0104050 (Pubitemid 39602945)
57. Walrand S., Guillet C., Boirie Y., Vasson M.-P., Insulin differentially regulates monocyte and polymorphonuclear neutrophil functions in healthy young and elderly humans. Journal of Clinical Endocrinology and Metabolism 2006 91 7 2738 2748 2-s2.0-33745789024 10.1210/jc.2005-1619 (Pubitemid 44024646)
58. Rassias A. J., Givan A. L., Marrin C. A. S., Whalen K., Pahl J., Yeager M. P., Insulin increases neutrophil count and phagocytic capacity after cardiac surgery. Anesthesia and Analgesia 2002 94 5 1113 1119 2-s2.0-0036239340 (Pubitemid 34441817)
59. Laird A. M., Miller P. R., Kilgo P. D., Meredith J. W., Chang M. C., Relationship of early hyperglycemia to mortality in trauma patients. The Journal of Trauma 2004 56 5 1058 1062 2-s2.0-2942536490 (Pubitemid 38788732)
60. Tuvdendorj D., Zhang X. J., Chinkes D. L., Aarsland A., Kulp G. A., Jeschke M. G., Herndon D. N., Intensive insulin treatment increases donor site wound protein synthesis in burn patients. Surgery 2011 149 4 512 518 2-s2.0-79952700325 10.1016/j.surg.2010.10.021
61. Pham T. N., Warren A. J., Phan H. H., Molitor F., Greenhalgh D. G., Palmieri T. L., Impact of tight glycemic control in severely burned children. Journal of Trauma 2005 59 5 1148 1154 2-s2.0-30344470788 10.1097/01.ta. 0000188933.16637.68 (Pubitemid 43060971)
62. Murphy C. V., Coffey R., Cook C. H., Gerlach A. T., Miller S. F., Early glycemic control in critically Ill patients with burn injury. Journal of Burn Care and Research 2011 32 6 583 590 2-s2.0-81155131026 10.1097/BCR. 0b013e31822dc3da
63. Vespa P., Boonyaputthikul R., McArthur D. L., Miller C., Etchepare M., Bergsneider M., Glenn T., Martin N., Hovda D., Intensive insulin therapy reduces microdialysis glucose values without altering glucose utilization or improving the lactate/pyruvate ratio after traumatic brain injury. Critical Care Medicine 2006 34 3 850 856 2-s2.0-33644585056 10.1097/01.CCM.0000201875.12245.6F
64. Frontera J. A., Intensive versus conventional insulin therapy in critically ill neurologic patients: still searching for the sweet spot. Neurocritical Care 2010 13 3 295 298 2-s2.0-78649716193 10.1007/s12028-010-9458- 7
65. Eakins J., Blood glucose control in the trauma patient. Journal of diabetes science and technology 2009 3 6 1373 1376 2-s2.0-77957312124
66. Kutcher M. E., Pepper M. B., Morabito D., Sunjaya D., Knudson M. M., Cohen M. J., Finding the sweet spot: identification of optimal glucose levels in critically injured patients. Journal of Trauma 2011 71 5 1108 1114 2-s2.0-81455144954 10.1097/TA.0b013e318232e35b
67. Gore D. C., Wolf S. E., Sanford A., Herndon D. N., Wolfe R. R., Influence of metformin on glucose intolerance and muscle catabolism following severe burn injury. Annals of Surgery 2005 241 2 334 342 2-s2.0-12744280722 10.1097/01.sla.0000152013.23032.d1
68. Cree M. G., Zwetsloot J. J., Herndon D. N., Qian T., Morio B., Fram R., Sanford A. P., Aarsland A., Wolfe R. R., Insulin sensitivity and mitochondrial function are improved in children with burn injury during a randomized controlled trial of fenofibrate. Annals of Surgery 2007 245 2 214 221 2-s2.0-33846465014 10.1097/01.sla.0000250409.51289.ca (Pubitemid 46148480)
69. Elijah I. E., Børsheim E., Maybauer D. M., Finnerty C. C., Herndon D. N., Maybauer M. O., Role of the PPAR- α agonist fenofibrate in severe pediatric burn. Burns 2012 38 4 481 486 2-s2.0-84859801219 10.1016/j.burns.2011. 12.004
70. Seok J., Warren H. S., Cuenca A. G., Genomic responses in mouse models poorly mimic human inflammatory diseases. Proceedings of the National Academy of Sciences of the United States of America 2013 110 9 3507 3512 10.1073/pnas.1222878110