메뉴 건너뛰기




Volumn 245, Issue 2, 2007, Pages 214-221

Insulin sensitivity and mitochondrial function are improved in children with burn injury during a randomized controlled trial of fenofibrate

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CITRATE SYNTHASE; CYTOCHROME C OXIDASE; FENOFIBRATE; GLUCOSE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PLACEBO; PYRUVIC ACID; TYROSINE;

EID: 33846465014     PISSN: 00034932     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.sla.0000250409.51289.ca     Document Type: Article
Times cited : (102)

References (42)
  • 1
    • 0000069234 scopus 로고
    • Studies of the absorption and metabolism of glucose following injury: The systemic response to injury
    • Howard JM. Studies of the absorption and metabolism of glucose following injury: the systemic response to injury. Ann Surg. 1955;141: 321-326.
    • (1955) Ann Surg , vol.141 , pp. 321-326
    • Howard, J.M.1
  • 2
    • 0022391426 scopus 로고
    • Glucose metabolism in burn injury: A review
    • Wolfe RR. Glucose metabolism in burn injury: a review. J Burn Care Rehabil. 1985;6:408-418.
    • (1985) J Burn Care Rehabil , vol.6 , pp. 408-418
    • Wolfe, R.R.1
  • 3
    • 0028158442 scopus 로고
    • Insulin resistance after abdominal surgery
    • Thorell A, Efendic S, Gutniak M, et al. Insulin resistance after abdominal surgery. Br J Surg. 1994;81:59-63.
    • (1994) Br J Surg , vol.81 , pp. 59-63
    • Thorell, A.1    Efendic, S.2    Gutniak, M.3
  • 4
    • 0035829852 scopus 로고    scopus 로고
    • Intensive insulin therapy in the critically ill patients
    • van den Berghe G, Wouters P, Weekers F, et al. Intensive insulin therapy in the critically ill patients. N Engl J Med. 2001;345:1359-1367.
    • (2001) N Engl J Med , vol.345 , pp. 1359-1367
    • van den Berghe, G.1    Wouters, P.2    Weekers, F.3
  • 5
    • 0034773026 scopus 로고    scopus 로고
    • Association of hyperglycemia with increased mortality after severe burn injury
    • Gore DC, Chinkes D, Heggers J, et al. Association of hyperglycemia with increased mortality after severe burn injury. J Trauma. 2001;51:540-544.
    • (2001) J Trauma , vol.51 , pp. 540-544
    • Gore, D.C.1    Chinkes, D.2    Heggers, J.3
  • 6
    • 33846426173 scopus 로고    scopus 로고
    • Fenofibrate improves muscle mitochondrial oxidative capacity after burn trauma
    • Qian T, Cree M, Aarsland A, et al. Fenofibrate improves muscle mitochondrial oxidative capacity after burn trauma. FASEB J. 2005;19:A565.
    • (2005) FASEB J , vol.19
    • Qian, T.1    Cree, M.2    Aarsland, A.3
  • 7
    • 17244367124 scopus 로고    scopus 로고
    • Burn injury causes mitochondrial dysfunction in skeletal muscle
    • Padfield KE, Astrakas LG, Zhang Q, et al. Burn injury causes mitochondrial dysfunction in skeletal muscle. Proc Natl Acad Sci USA. 2005;102:5368-5373.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 5368-5373
    • Padfield, K.E.1    Astrakas, L.G.2    Zhang, Q.3
  • 8
    • 0033662752 scopus 로고    scopus 로고
    • Skeletal muscle apoptosis after burns is associated with activation of proapoptotic signals
    • Yasuhara S, Perez ME, Kanakubo E, et al. Skeletal muscle apoptosis after burns is associated with activation of proapoptotic signals. Am J Physiol Endocrinol Metab. 2000;279:E1114-E1121.
    • (2000) Am J Physiol Endocrinol Metab , vol.279
    • Yasuhara, S.1    Perez, M.E.2    Kanakubo, E.3
  • 9
    • 0022799570 scopus 로고
    • Functional changes in rat-liver mitochondria during the early phase of burn injury
    • Wang XM, Chen KM, Wang Y, et al. Functional changes in rat-liver mitochondria during the early phase of burn injury. Burns Incl Therm Inj. 1986;12:461-464.
    • (1986) Burns Incl Therm Inj , vol.12 , pp. 461-464
    • Wang, X.M.1    Chen, K.M.2    Wang, Y.3
  • 10
    • 11444259403 scopus 로고    scopus 로고
    • Protection of hepatocyte mitochondrial ultrastructure and function by strict blood glucose control with insulin in critically ill patients
    • Vanhorebeek I, De Vos R, Mesotten D, et al. Protection of hepatocyte mitochondrial ultrastructure and function by strict blood glucose control with insulin in critically ill patients. Lancet. 2005;365:53-59.
    • (2005) Lancet , vol.365 , pp. 53-59
    • Vanhorebeek, I.1    De Vos, R.2    Mesotten, D.3
  • 11
    • 4544386330 scopus 로고    scopus 로고
    • Unraveling the cellular mechanism of insulin resistance in humans: New insights from magnetic resonance spectroscopy
    • Shulman GI. Unraveling the cellular mechanism of insulin resistance in humans: new insights from magnetic resonance spectroscopy. Physiology (Bethesda). 2004;19:183-190.
    • (2004) Physiology (Bethesda) , vol.19 , pp. 183-190
    • Shulman, G.I.1
  • 12
    • 0036788293 scopus 로고    scopus 로고
    • Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
    • Kelley DE, He J, Menshikova EV, et al. Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes. 2002;51:2944-2950.
    • (2002) Diabetes , vol.51 , pp. 2944-2950
    • Kelley, D.E.1    He, J.2    Menshikova, E.V.3
  • 13
    • 0037352784 scopus 로고    scopus 로고
    • Metformin blunts stress-induced hyperglycemia after thermal injury
    • Gore DC, Wolf SE, Herndon DN, et al. Metformin blunts stress-induced hyperglycemia after thermal injury. J Trauma. 2003;54:555-561.
    • (2003) J Trauma , vol.54 , pp. 555-561
    • Gore, D.C.1    Wolf, S.E.2    Herndon, D.N.3
  • 14
    • 2542491213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma in diabetes and metabolism
    • Rangwala SM, Lazar MA. Peroxisome proliferator-activated receptor gamma in diabetes and metabolism. Trends Pharmacol Sci. 2004;25:331-336.
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 331-336
    • Rangwala, S.M.1    Lazar, M.A.2
  • 15
    • 2942592296 scopus 로고    scopus 로고
    • Support of the metabolic response to burn injury
    • Herndon DN, Tompkins RG. Support of the metabolic response to burn injury. Lancet. 2004;363:1895-1902.
    • (2004) Lancet , vol.363 , pp. 1895-1902
    • Herndon, D.N.1    Tompkins, R.G.2
  • 16
    • 0036686288 scopus 로고    scopus 로고
    • Fenofibrate improves insulin sensitivity in connection with intramuscular lipid content, muscle fatty acid-binding protein, and beta-oxidation in skeletal muscle
    • Furuhashi M, Ura N, Murakami H, et al. Fenofibrate improves insulin sensitivity in connection with intramuscular lipid content, muscle fatty acid-binding protein, and beta-oxidation in skeletal muscle. J Endocrinol. 2002;174:321-329.
    • (2002) J Endocrinol , vol.174 , pp. 321-329
    • Furuhashi, M.1    Ura, N.2    Murakami, H.3
  • 17
    • 0035024343 scopus 로고    scopus 로고
    • A potent PPARalpha agonist stimulates mitochondrial fatty acid beta-oxidation in liver and skeletal muscle
    • Minnich A, Tian N, Byan L, et al. A potent PPARalpha agonist stimulates mitochondrial fatty acid beta-oxidation in liver and skeletal muscle. Am J Physiol Endocrinol Metab. 2001;280:E270-E279.
    • (2001) Am J Physiol Endocrinol Metab , vol.280
    • Minnich, A.1    Tian, N.2    Byan, L.3
  • 18
    • 0036121471 scopus 로고    scopus 로고
    • Severe hypertriglyceridemia with insulin resistance is associated with systemic inflammation: Reversal with bezafibrate therapy in a randomized controlled trial
    • Jonkers IJ, Mohrschladt MF, Westendorp RG, et al. Severe hypertriglyceridemia with insulin resistance is associated with systemic inflammation: reversal with bezafibrate therapy in a randomized controlled trial. Am J Med. 2002;112:275-280.
    • (2002) Am J Med , vol.112 , pp. 275-280
    • Jonkers, I.J.1    Mohrschladt, M.F.2    Westendorp, R.G.3
  • 19
    • 23944455362 scopus 로고    scopus 로고
    • Post burn muscle wasting and the effects of treatments
    • Pereira C, Murphy K, Jeschke M, et al. Post burn muscle wasting and the effects of treatments. Int J Biochem Cell Biol. 2005;37:1948-1961.
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 1948-1961
    • Pereira, C.1    Murphy, K.2    Jeschke, M.3
  • 21
    • 0035020539 scopus 로고    scopus 로고
    • Muscle fatty acid oxidative capacity is a determinant of whole body fat oxidation in elderly people
    • Morio B, Hocquette JF, Montaurier C, et al. Muscle fatty acid oxidative capacity is a determinant of whole body fat oxidation in elderly people. Am J Physiol Endocrinol Metab. 2001;280:E143-E149.
    • (2001) Am J Physiol Endocrinol Metab , vol.280
    • Morio, B.1    Hocquette, J.F.2    Montaurier, C.3
  • 22
  • 23
    • 0023255871 scopus 로고
    • Mitochondrial respiratory parameters in cardiac tissue: A novel method of assessment by using saponin-skinned fibers
    • Veksler VI, Kuznetsov AV, Sharov VG, et al. Mitochondrial respiratory parameters in cardiac tissue: a novel method of assessment by using saponin-skinned fibers. Biochim Biophys Acta. 1987;892:191-196.
    • (1987) Biochim Biophys Acta , vol.892 , pp. 191-196
    • Veksler, V.I.1    Kuznetsov, A.V.2    Sharov, V.G.3
  • 24
    • 0017279627 scopus 로고
    • Activities of citrate synthase and NAD -linked and NADP -linked isocitrate dehydrogenase in muscle from vertebrates and invertebrates
    • Alp PR, Newsholme EA, Zammit VA. Activities of citrate synthase and NAD -linked and NADP -linked isocitrate dehydrogenase in muscle from vertebrates and invertebrates. Biochem J. 1976;154:689-700.
    • (1976) Biochem J , vol.154 , pp. 689-700
    • Alp, P.R.1    Newsholme, E.A.2    Zammit, V.A.3
  • 25
    • 71849104860 scopus 로고
    • Protein measurement with the Folin phenol reagent
    • Lowry OH, Rosebrough NJ, Farr AL, et al. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951;193:265-275.
    • (1951) J Biol Chem , vol.193 , pp. 265-275
    • Lowry, O.H.1    Rosebrough, N.J.2    Farr, A.L.3
  • 26
    • 0033056557 scopus 로고    scopus 로고
    • Dephosphorylation increases insulinstimulated receptor kinase activity in skeletal muscle of obese Zucker rats
    • Zhou Q, Dolan PL, Dohm GL. Dephosphorylation increases insulinstimulated receptor kinase activity in skeletal muscle of obese Zucker rats. Mol Cell Biochem. 1999;194:209-216.
    • (1999) Mol Cell Biochem , vol.194 , pp. 209-216
    • Zhou, Q.1    Dolan, P.L.2    Dohm, G.L.3
  • 27
    • 11844254843 scopus 로고    scopus 로고
    • Fenofibrate treatment is associated with better glycemic control and lower serum leptin and insulin levels in type 2 diabetic patients with hypertriglyceridemia
    • Damci T, Tatliagac S, Osar Z, et al. Fenofibrate treatment is associated with better glycemic control and lower serum leptin and insulin levels in type 2 diabetic patients with hypertriglyceridemia. Eur J Intern Med. 2003;14:357-360.
    • (2003) Eur J Intern Med , vol.14 , pp. 357-360
    • Damci, T.1    Tatliagac, S.2    Osar, Z.3
  • 28
    • 0141763847 scopus 로고    scopus 로고
    • Prediabetes in obese youth: A syndrome of impaired glucose tolerance, severe insulin resistance, and altered myocellular and abdominal fat partitioning
    • Weiss R, Dufour S, Taksali SE, et al. Prediabetes in obese youth: a syndrome of impaired glucose tolerance, severe insulin resistance, and altered myocellular and abdominal fat partitioning. Lancet. 2003;362:951-957.
    • (2003) Lancet , vol.362 , pp. 951-957
    • Weiss, R.1    Dufour, S.2    Taksali, S.E.3
  • 29
    • 0036774527 scopus 로고    scopus 로고
    • Glucose tolerance, insulin sensitivity, and insulin secretion in children born small for gestational age
    • Veening MA, Van Weissenbruch MM, Delemarre-Van De Waal HA. Glucose tolerance, insulin sensitivity, and insulin secretion in children born small for gestational age. J Clin Endocrinol Metab. 2002;87:4657-4661.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 4657-4661
    • Veening, M.A.1    Van Weissenbruch, M.M.2    Delemarre-Van De Waal, H.A.3
  • 30
    • 0018567260 scopus 로고
    • Glucose metabolism in severely burned patients
    • Wolfe RR, Durkot MJ, Allsop JR, et al. Glucose metabolism in severely burned patients. Metabolism. 1979;28:1031-1039.
    • (1979) Metabolism , vol.28 , pp. 1031-1039
    • Wolfe, R.R.1    Durkot, M.J.2    Allsop, J.R.3
  • 31
    • 20044369980 scopus 로고    scopus 로고
    • Insulin resistance and impaired glucose tolerance in obese children and adolescents referred to a tertiarycare center in Israel
    • Shalitin S, Abrahami M, Lilos P, et al. Insulin resistance and impaired glucose tolerance in obese children and adolescents referred to a tertiarycare center in Israel. Int J Obes (Lond). 2005;29:571-578.
    • (2005) Int J Obes (Lond) , vol.29 , pp. 571-578
    • Shalitin, S.1    Abrahami, M.2    Lilos, P.3
  • 32
    • 0038369154 scopus 로고    scopus 로고
    • Low adiponectin levels in adolescent obesity: A marker of increased intramyocellular lipid accumulation
    • Weiss R, Dufour S, Groszmann A, et al. Low adiponectin levels in adolescent obesity: a marker of increased intramyocellular lipid accumulation. J Clin Endocrinol Metab. 2003;88:2014-2018.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2014-2018
    • Weiss, R.1    Dufour, S.2    Groszmann, A.3
  • 33
    • 0019992469 scopus 로고
    • Mechanisms of insulin resistance following injury
    • Black PR, Brooks DC, Bessey PQ, et al. Mechanisms of insulin resistance following injury. Ann Surg. 1982;196:420-435.
    • (1982) Ann Surg , vol.196 , pp. 420-435
    • Black, P.R.1    Brooks, D.C.2    Bessey, P.Q.3
  • 34
    • 12744267799 scopus 로고    scopus 로고
    • Molecular mechanisms of alcoholic fatty liver: Role of peroxisome proliferator-activated receptor alpha
    • Crabb DW, Galli A, Fischer M, et al. Molecular mechanisms of alcoholic fatty liver: role of peroxisome proliferator-activated receptor alpha. Alcohol. 2004;34:35-38.
    • (2004) Alcohol , vol.34 , pp. 35-38
    • Crabb, D.W.1    Galli, A.2    Fischer, M.3
  • 35
    • 0030845178 scopus 로고    scopus 로고
    • Analysis of thermal injury-induced insulin resistance in rodents: Implication of postreceptor mechanisms
    • Ikezu T, Okamoto T, Yonezawa K, et al. Analysis of thermal injury-induced insulin resistance in rodents: implication of postreceptor mechanisms. J Biol Chem. 1997;272:25289-25295.
    • (1997) J Biol Chem , vol.272 , pp. 25289-25295
    • Ikezu, T.1    Okamoto, T.2    Yonezawa, K.3
  • 36
    • 26444436274 scopus 로고    scopus 로고
    • Molecular mechanism(s) of burn-induced insulin resistance in murine skeletal muscle: Role of IRS phosphorylation
    • Zhang Q, Carter EA, Ma BY, et al. Molecular mechanism(s) of burn-induced insulin resistance in murine skeletal muscle: role of IRS phosphorylation. Life Sci. 2005;77:3068-3077.
    • (2005) Life Sci , vol.77 , pp. 3068-3077
    • Zhang, Q.1    Carter, E.A.2    Ma, B.Y.3
  • 37
    • 0028903232 scopus 로고
    • Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects
    • Goodyear LJ, Giorgino F, Sherman LA, et al. Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects. J Clin Invest. 1995;95:2195-2204.
    • (1995) J Clin Invest , vol.95 , pp. 2195-2204
    • Goodyear, L.J.1    Giorgino, F.2    Sherman, L.A.3
  • 38
    • 12344305124 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and type 2 diabetes
    • Lowell BB, Shulman GI. Mitochondrial dysfunction and type 2 diabetes. Science. 2005;307:384-387.
    • (2005) Science , vol.307 , pp. 384-387
    • Lowell, B.B.1    Shulman, G.I.2
  • 39
    • 0025765874 scopus 로고
    • Isotopic evaluation of the metabolism of pyruvate and related substrates in normal adult volunteers and severely burned children: Effect of dichloroacetate and glucose infusion
    • Wolfe RR, Jahoor F, Herndon DN, et al. Isotopic evaluation of the metabolism of pyruvate and related substrates in normal adult volunteers and severely burned children: effect of dichloroacetate and glucose infusion. Surgery. 1991;110:54-67.
    • (1991) Surgery , vol.110 , pp. 54-67
    • Wolfe, R.R.1    Jahoor, F.2    Herndon, D.N.3
  • 40
    • 23644434842 scopus 로고    scopus 로고
    • Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without uncoupling respiration in muscle cells
    • MacLellan JD, Gerrits MF, Gowing A, et al. Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without uncoupling respiration in muscle cells. Diabetes. 2005;54:2343-2350.
    • (2005) Diabetes , vol.54 , pp. 2343-2350
    • MacLellan, J.D.1    Gerrits, M.F.2    Gowing, A.3
  • 41
    • 0033086243 scopus 로고    scopus 로고
    • Mitochondria mediate tumor necrosis factor-alpha/NF-kappaB signaling in skeletal muscle myotubes
    • Li YP, Atkins CM, Sweatt JD, et al. Mitochondria mediate tumor necrosis factor-alpha/NF-kappaB signaling in skeletal muscle myotubes. Antioxid Redox Signal. 1999;1:97-104.
    • (1999) Antioxid Redox Signal , vol.1 , pp. 97-104
    • Li, Y.P.1    Atkins, C.M.2    Sweatt, J.D.3
  • 42
    • 8544244084 scopus 로고    scopus 로고
    • PKC-theta knockout mice are protected from fat-induced insulin resistance
    • Kim JK, Fillmore JJ, Sunshine MJ, et al. PKC-theta knockout mice are protected from fat-induced insulin resistance. J Clin Invest. 2004;114: 823-827.
    • (2004) J Clin Invest , vol.114 , pp. 823-827
    • Kim, J.K.1    Fillmore, J.J.2    Sunshine, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.