Agonist-dependent failure of neutrophil function in diabetes correlates with extent of hyperglycemia

Journal of Leukocyte Biology

Volumn 70, Issue 3, 2001, Pages 395-404

  McManus, Linda M ^a,b   Bloodworth, Rebecca C ^a   Prihoda, Thomas J ^a   Blodgett, Janet L ^a,c   Pinckard, R Neal ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

Author keywords

fMLP; GPCR; Inflammation; LTB4; PAF

Indexed keywords

CALCIMYCIN; G PROTEIN COUPLED RECEPTOR; GLUCOSE; GLYCOSYLATED HEMOGLOBIN; LEUKOTRIENE B4; LYSOSOME ENZYME; PHORBOL 13 ACETATE 12 MYRISTATE; ZYMOSAN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ASSAY; ENZYME RELEASE; FEMALE; GLUCOSE BLOOD LEVEL; HOST RESISTANCE; HUMAN; HUMAN CELL; HYPERGLYCEMIA; INFLAMMATION; LYSOSOME; MALE; NEUTROPHIL; PRIORITY JOURNAL;

ADULT; BLOOD GLUCOSE; CALCIMYCIN; CELLS, CULTURED; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS; FEMALE; HUMANS; HYPERGLYCEMIA; LEUKOTRIENE B4; LYSOSOMES; MALE; MIDDLE AGED; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHIL ACTIVATION; NEUTROPHILS; PLATELET ACTIVATING FACTOR; TETRADECANOYLPHORBOL ACETATE; ZYMOSAN;

EID: 0034840002     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (86)

1. Infections and diabetes: Mechanisms and prospects for prevention
2. Infection and diabetes: The case for glucose control
3. Chronic granulomatous disease: More than the lack of superoxide?
4. Genetic, biochemical, and clinical features of chronic granulomatous disease
5. Disorders of phagocytic cells
6. Impaired leucocyte functions in diabetic patients
7. Effect of tolrestat, an aldose reductase inhibitor, on neutrophil respiratory burst activity in diabetic patients
8. Effect of granulocyte-colony stimulating factor on generation of oxygen-derived free radicals and myeloperoxidase activity in neutrophils from poorly controlled NIDDM patients
9. Epalrestat, an aldose reductase inhibitor, improves an impaired generation of oxygen-derived free radicals by neutrophils from poorly controlled NIDDM patients
10. Reduced hydrogen peroxide production in neutrophils from patients with diabetes
11. Inhibition of phospholipase D and superoxide generation by glucose in diabetic neutrophils
12. Production of superoxide anion by polymorphonuclear leukocytes from diabetic patients with or without diabetic retinopathy
13. Polymorphonuclear leukocytes in non-insulin-dependent diabetes mellitus: Abnormalities in metabolism and function
14. Exploration of the various steps of polymorphonuclear neutrophil function in diabetic patients
15. Monitoring of polymorphonuclear leukocyte functions in diabetes mellitus - A comparative study of conventional radiometric function tests and low-light imaging systems
16. Polymorphonuclear cell-mediated phagocytosis and superoxide anion release in insulin-dependent diabetes mellitus
17. Prevalence of diabetes mellitus in odontogenic infections and oral candidiasis: An analysis of neutrophil suppression
18. Effects of ponalrestat, an aldose reductase inhibitor, on neutrophil killing of Escherichia coli and autonomic function in patients with diabetes mellitus
19. Impairment of polymorphonuclear leukocyte function and metabolic control of diabetes
20. Intracellular hydrogen peroxide production by peripheral phagocytes from diabetic patients: Dissociation between polymorphonuclear leucocytes and monocytes
21. Neutrophil adhesive dysfunction in diabetes mellitus, the role of cellular and plasma factors
22. Polymorphonuclear cell derangements in type I diabetes
23. The influence of thymus extracts on the chemotaxis of polymorphonuclear neutrophils (PMN) from patients with insulin-dependent diabetes mellitus
24. Neutrophil function in diabetes
25. Superoxide production and LDL oxidation by diabetic neutrophils
26. Impairment of the oxygen-dependent microbicidal mechanisms of polymorphonuclear neutrophils in patients with type 2 diabetes is not associated with increased susceptibility to infection
27. The role of aldose reductase inhibition in diabetic neutrophil phagocytosis and killing
28. Phagocyte oxidative metabolism in cyclosporine- or placebo-treated patients with insulin-dependent (type I) diabetes mellitus of recent onset
29. Evidence of polymorphonuclear neutrophil activation in patients with insulin-dependent diabetes mellitus
30. The effect of diabetes mellitus on chemotactic and bactericidal activity of human polymorphonuclear leukocytes
31. The influence of insulin-dependent diabetes mellitus (IDDM) duration on superoxide anion and hydrogen peroxide production by polymorphonuclear neutrophils
32. Modulation of platelet-activating factor (PAF) synthesis and release from human polymorphonuclear leukocytes (PMN): Role of extracellular calcium
33. A new micromethod for the colorimetric determination of inorganic phosphate
34. Differential responsiveness of human neutrophils to the autocrine actions of 1-O-alkyl-homologs and 1-acyl-analogs of platelet-activating factor (PAF)
35. Neutrophils autoinactivate secretory products by myeloperoxidase-catalyzed oxidation
36. Secretion and inactivation of myeloperoxidase by isolated neutrophils
37. Impaired superoxide anion production by PAF-primed diabetic PMN
38. The mammalian facilitative glucose transporter (GLUT) family
39. Conversion between two cytochalasin B-binding states of the human GLUT1 glucose transporter
40. Activation of G-protein coupled fMLP or PAF receptor directly triggers glucose transporter type 1 (GLUT1) translocation in Chinese hamster ovary (CHO) cells stably expressing fMLP or PAF receptor
41. Decreased leukotriene B4 synthesis by polymorphonuclear leukocytes from male patients with diabetes mellitus
42. The relationship between glycated hemoglobin and polymorphonuclear leukocyte leukotriene B4 release in people with diabetes mellitus
43. Leukotriene B4 costimulates 5-lipoxygenase activity in neutrophils via increased 5-lipoxygenase translocation
44. Lipid mediators up-regulate CD11b and prime for concordant superoxide and elastase release in human neutrophils
45. Hypertonic saline activates lipid-primed human neutrophils for enhanced elastase release
46. Changes in superoxide dismutase activities and concentrations and myeloperoxidase activities in leukocytes from patients with diabetes mellitus
47. Bactericidal proteins and neutral proteases in diabetes neutrophils
48. Neutrophil activation detected by increased neutrophil elastase activity in type 1 (insulin-dependent) diabetes mellitus
49. The functions of circulatory, polymorphonuclear leukocytes in diabetic patients with and without diabetic triopathy
50. Improvement of an impaired chemiluminescence response to formyl-methionyl-leucyl-phenylalanine in neutrophils from patients with non insulin dependent diabetes mellitus by recombinant human granulocyte-colony stimulating factor
51. Polymorphonuclear leukocyte membrane fluidity before and after activation in subjects with insulin resistance
52. Effects of insulin on N-formyl-methionyl-leucyl-phenylalanine (fMet-Leu-Phe)-stimulated production of reactive oxygen metabolites from normal human neutrophils
53. Neutrophils: Molecules, functions and pathophysiological aspects
54. Inhibition of apoptosis and prolongation of neutrophil functional longevity by inflammatory mediators
55. Apoptosis of neutrophils
56. Regulation of neutrophil apoptosis - Its biological significance in inflammation and the immune response
57. Apoptosis and the regulation of neutrophil lifespan
58. Selective activation and functional significance of p38α mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils
59. Absence of lipopolysaccharide-induced inhibition of neutrophil apoptosis in patients with diabetes
60. Altered postreceptor signal transduction of formyl-met-leu-phe receptors in polymorphonuclear leukocytes of patients with non-insulin-dependent diabetes mellitus
61. 2+ content in platelets from a group of type II diabetic patients with macrovascular complications
62. 2+ content and membrane fluidity of platelets and polymorphonuclear leucocytes in diabetes mellitus
63. i activity in diabetes
64. Effect of glucose on the respiratory burst of circulating neutrophils from asthmatics
65. Glucose suppresses superoxide generation in normal neutrophils: Interference in phospholipase D activation
66. Peritoneal dialysis fluid inhibition of phagocyte function: Effects of osmolality and glucose concentration
67. Inhibition of C5a-induced actin polymerization, chemotaxis, and phagocytosis of human polymorphonuclear neutrophils incubated in a glucose-based dialysis solution
68. The influence of aldose reductase on the oxidative burst in diabetic neutrophils
69. Involvement of peripheral polymorphonuclear leukocytes in oxidative stress and inflammation in type 2 diabetic patients
70. Relative effects of glucose and glutamine on reactive oxygen intermediate production by neutrophils
71. Inhibition of polymorphonuclear leukocyte respiratory burst by elevated glucose concentrations in vitro
72. Different effects of glucose on extracellular and intracellular respiratory burst response in normal human neutrophils activated with the soluble agonist fMet-Leu-Phe
73. Roles of the AGE-RAGE system in vascular injury in diabetes
74. In vitro glycoxidation alters the interactions between collagens and human polymorphonuclear leucocytes
75. Cell volume-dependent regulation of L-selectin shedding in neutrophils
76. Hypertonicity prevents lipopolysaccharide-stimulated CD11b/CD18 expression in human neutrophils in vitro: Role for p38 inhibition
77. + exchanger activation during shrinkage of human neutrophils
78. The role of cellular hydration in the regulation of cell function
79. Prognostic implications of hyperglycaemia in paediatric head injury
80. Stress hyperglycemia in minimally invasive surgery
81. Age-related differences in the metabolic response to injury
82. Gunshot wounds in brains of children: Prognostic variables in mortality, course, and outcome
83. Early prediction of neurological outcome after falls in children: Metabolic and clinical markers
84. The influence of hyperglycemia on neurological outcome in patients with severe head injury
85. Effect of growth hormone therapy in burn patients on conservative treatment
86. Metabolic responses and nutritional therapy in patients with severe head injuries