Effect of hyperglycemia on human monocyte activation

Journal of Investigative Medicine

Volumn 59, Issue 4, 2011, Pages 661-667

  Nandy, Debashis ^a   Janardhanan, Rajiv ^b   Mukhopadhyay, Debabrata ^b   Basu, Ananda ^a  

^a Mayo Clinic   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

Author keywords

Hyperglycemia; Monocyte; p101; p110 ; THP 1

Indexed keywords

GLUCOSE; GLYCOGEN SYNTHASE KINASE 3BETA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ARTICLE; CELL ACTIVATION; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HYPERGLYCEMIA; MONOCYTE; MONOLAYER CULTURE; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STRESS FIBER; UPREGULATION;

EID: 80053599750     PISSN: 17088267     EISSN: 17088267     Source Type: Journal    
DOI: 10.2310/JIM.0b013e31820ee432     Document Type: Article

References (32)

1. Haffner SM, Lehto S, Ronnemaa T, et al. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med. 1998;39:229-234. (Pubitemid 28350165)
2. Eeg-Olofsson K, Cederholm J, Nilsson PM, et al. Glycemic control and cardiovascular disease in 7454 patients with type 1 diabetes: an observational study from the Swedish National Diabetes Register (NDR). Diabetes Care. 2010;33:1640-1646.
3. Brindisi MC, Rabasa-Lhoret R, Chiasson JL. Postprandial hyperglycaemia: to treat or not to treat? Diabetes Metab. 2006; 32:105-111.
4. Altannavch TS, Roubalova K, Kucera P, et al. Effect of high glucose concentrations on expression of ELAM-1, VCAM-1 and ICAM-1 in HUVEC with and without cytokine activation. Physiol Res. 2004;53:77-82. (Pubitemid 38295544)
5. Schmidt AM, Hori O, Chen JX, et al. Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes. J Clin Invest. 1995;96:1395-1403.
6. Otsuka A, Azuma K, Iesaki T, et al. Temporary hyperglycaemia provokes monocyte adhesion to endothelial cells in rat thoracic aorta. Diabetologia. 2005;48:2667-2674. (Pubitemid 41738236)
7. Piga R, Naito Y, Kokura S, et al. Short-term high glucose exposure induces monocyte-endothelial cells adhesion and transmigration by increasing VCAM-1 and MCP-1 expression in human aortic endothelial cells. Atherosclerosis. 2007;193:328-334. (Pubitemid 47058120)
8. Nandy D, Asmann YW, Mukhopadhyay D, et al. Role of AKT-glycogen synthase kinase axis in monocyte activation in humans with and without type 2 diabetes. J Cell Mol Med. 2010;14: 1396-1407.
9. Das A, Shergill U, Thakur L, et al. Ephrin B2/EphB4 pathway in hepatic stellate cells stimulates Erk-dependent VEGF production and sinusoidal endothelial cell recruitment. Am J Physiol Gastrointest Liver Physiol. 2010;298:G908-G915.
10. Bussolino F, Fischer E, Turrini F, et al. Platelet-activating factor enhances complement-dependent phagocytosis of diamide-treated erythrocytes by human monocytes through activation of protein kinase C and phosphorylation of complement receptor type one (CR1). J Biol Chem. 1989;264:21711-21719. (Pubitemid 20028740)
11. Hartnett ME, Martiniuk D, Byfield G, et al. Neutralizing VEGF decreases tortuosity and alters endothelial cell division orientation in arterioles and veins in a rat model of ROP: relevance to plus disease. Invest Ophthalmol Vis Sci. 2008;49:3107-3114.
12. Muller WA, Ratti CM, McDonnell SL, et al. A human endothelial cell-restricted, externally disposed plasmalemmal protein enriched in intercellular junctions. J Exp Med. 1989;170:399-414. (Pubitemid 19204271)
13. Randolph GJ, Beaulieu S, Lebecque S, et al. Differentiation of monocytes into dendritic cells in a model of transendothelial trafficking. Science. 1998;282:480-483. (Pubitemid 28483676)
14. Reddy RC, Narala VR, Keshamouni VG, et al. Sepsis-induced inhibition of neutrophil chemotaxis is mediated by activation of peroxisome proliferator-activated receptor-{gamma}. Blood. 2008; 112:4250-4258.
15. Haston WS. F-actin distribution in polymorphonuclear leucocytes. J Cell Sci. 1987;88(Pt 4):495-501.
16. Ruderman NB, Williamson JR, Brownlee M. Glucose and diabetic vascular disease. FASEB J. 1992;6:2905-2914.
17. Gerrity RG. The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions. Am J Pathol. 1981;103:181-190. (Pubitemid 11112973)
18. Li J, Jin HB, Sun YM, et al. KB-R7943 inhibits high glucose-induced endothelial ICAM-1 expression and monocyte-endothelial adhesion. Biochem Biophys Res Commun. 2010;392:516-519.
19. Manduteanu I, Pirvulescu M, Gan AM, et al. Similar effects of resistin and high glucose on P-selectin and fractalkine expression and monocyte adhesion in human endothelial cells. Biochem Biophys Res Commun. 2010391:1443-1448.
20. Franke TF, Kaplan DR, Cantley LC, et al. Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate. Science. 1997;275:665-668. (Pubitemid 27061333)
21. Jiang BH, Zheng JZ, Aoki M, et al. Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells. Proc Natl Acad Sci U S A. 2000;97:1749-1753. (Pubitemid 30118514)
22. Varma S, Lal BK, Zheng R, et al. Hyperglycemia alters PI3k and Akt signaling and leads to endothelial cell proliferative dysfunction. Am J Physiol Heart Circ Physiol. 2005;289:H1744-1751. (Pubitemid 41369020)
23. Ho FM, Lin WW, Chen BC, et al. High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway. Cell Signal. 2006;18:391-399. (Pubitemid 41661354)
24. Radhakrishnan Y, Maile LA, Ling Y, et al. Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cells. J Biol Chem. 2008;283:16320-16331.
25. Andrews S, Stephens LR, Hawkins PT. PI3K class IB pathway in neutrophils. Sci STKE. 2007;407:cm3.
26. Heller R, Chang Q, Ehrlich G, et al. Overlapping and distinct roles for PI3Kbeta and gamma isoforms in S1P-induced migration of human and mouse endothelial cells. Cardiovasc Res. 2008;80:96-105.
27. Sasaki T, Irie-Sasaki J, Jones RG, et al. Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration. Science. 2000;287:1040-1046.
28. Hirsch E, Katanaev VL, Garlanda C, et al. Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation. Science. 2000;287:1049-1053.
29. Wymann MP, Pirola L. Structure and function of phosphoinositide 3-kinases. Biochim Biophys Acta. 1998;1436:127-150.
30. Vanhaesebroeck B, Leevers SJ, Ahmadi K, et al. Synthesis and function of 3-phosphorylated inositol lipids. Annu Rev Biochem. 2001;70: 535-602. (Pubitemid 32662219)
31. Stephens L, Smrcka A, Cooke FT, et al. A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits. Cell. 1994;77:83-93. (Pubitemid 24184690)
32. Thomason PA, James SR, Casey PJ, et al. A G-protein beta gamma-subunit-responsive phosphoinositide 3-kinase activity in human platelet cytosol. J Biol Chem. 1994;269:16525-16528.