-
1
-
-
0042634362
-
Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory
-
Turner PR, O'Connor K, TateWP, AbrahamWC(2003) Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory. Prog Neurobiol 70, 1-32.
-
(2003)
Prog Neurobiol
, vol.70
, pp. 1-32
-
-
Turner, P.R.1
O'connor, K.2
Tate, W.P.3
Abraham, W.C.4
-
2
-
-
33750151421
-
Subcellular trafficking of the amyloid precursor protein gene family and its pathogenic role in Alzheimer's disease
-
Kins S, Lauther N, Szodorai A, Beyreuther K (2006) Subcellular trafficking of the amyloid precursor protein gene family and its pathogenic role in Alzheimer's disease. Neurodegener Dis 3, 218-226.
-
(2006)
Neurodegener Dis
, vol.3
, pp. 218-226
-
-
Kins, S.1
Lauther, N.2
Szodorai, A.3
Beyreuther, K.4
-
3
-
-
33750151420
-
The functions of mammalian amyloid precursor protein and related amyloid precursor-like proteins
-
Anliker B, Müller U (2006) The functions of mammalian amyloid precursor protein and related amyloid precursor-like proteins. Neurodegener Dis 3, 239-246.
-
(2006)
Neurodegener Dis
, vol.3
, pp. 239-246
-
-
Anliker, B.1
Müller, U.2
-
4
-
-
84861721553
-
Functions of the APP gene family in the nervous system: Insights from mouse models
-
Aydin D, Weyer SW, Müller UC (2012) Functions of the APP gene family in the nervous system: Insights from mouse models. Exp Brain Res 217, 423-434.
-
(2012)
Exp Brain Res
, vol.217
, pp. 423-434
-
-
Aydin, D.1
Weyer, S.W.2
Müller, U.C.3
-
5
-
-
84862837302
-
Role of APP for dendritic spine formation and stability
-
Jung CK, Herms J (2012) Role of APP for dendritic spine formation and stability. Exp Brain Res 217, 463-470.
-
(2012)
Exp Brain Res
, vol.217
, pp. 463-470
-
-
Jung, C.K.1
Herms, J.2
-
6
-
-
84862838270
-
The role of APP and APLP for synaptic transmission, plasticity, and network function: Lessons from genetic mouse models
-
Korte M, Herrmann U, Zhang X, Draguhn A (2012) The role of APP and APLP for synaptic transmission, plasticity, and network function: Lessons from genetic mouse models. Exp Brain Res 217, 435-440.
-
(2012)
Exp Brain Res
, vol.217
, pp. 435-440
-
-
Korte, M.1
Herrmann, U.2
Zhang, X.3
Draguhn, A.4
-
7
-
-
84865278636
-
Amyloid precursor protein (APP) regulates synaptic structure and function
-
Tyan SH, Shih AY, Walsh JJ, Maruyama H, Sarsoza F, Ku L, Eggert S, Hof PR, Koo EH, Dickstein DL (2012) Amyloid precursor protein (APP) regulates synaptic structure and function. Mol Cell Neurosci 51, 43-52.
-
(2012)
Mol Cell Neurosci
, vol.51
, pp. 43-52
-
-
Tyan, S.H.1
Shih, A.Y.2
Walsh, J.J.3
Maruyama, H.4
Sarsoza, F.5
Ku, L.6
Eggert, S.7
Hof, P.R.8
Koo, E.H.9
Dickstein, D.L.10
-
8
-
-
84655160766
-
Proteolytic processing of Alzheimer's -amyloid precursor protein
-
Zhang H, Ma Q, ZhangYW, XuH(2012) Proteolytic processing of Alzheimer's -amyloid precursor protein. J Neurochem 120(Suppl 1), 9-21.
-
(2012)
J Neurochem
, vol.120
, Issue.SUPPL. 1
, pp. 9-21
-
-
Zhang, H.1
Ma, Q.2
Zhang, Y.W.3
Xu, H.4
-
9
-
-
84878946078
-
The amyloid precursor protein: A biochemical enigma in brain development, function and disease
-
Nalivaeva NN, Turner AJ (2013) The amyloid precursor protein: A biochemical enigma in brain development, function and disease. FEBS Lett 587, 2046-2054.
-
(2013)
FEBS Lett
, vol.587
, pp. 2046-2054
-
-
Nalivaeva, N.N.1
Turner, A.J.2
-
10
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
Hardy J, Selkoe DJ (2002) The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics. Science 297, 353-356.
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
11
-
-
77954132249
-
Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: From synapses toward neural networks
-
Palop JJ, Mucke L (2010) Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: From synapses toward neural networks. Nat Neurosci 13, 812-818.
-
(2010)
Nat Neurosci
, vol.13
, pp. 812-818
-
-
Palop, J.J.1
Mucke, L.2
-
12
-
-
0037174618
-
Alzheimer's disease is a synaptic failure
-
Selkoe DJ (2002) Alzheimer's disease is a synaptic failure. Science 298, 789-791.
-
(2002)
Science
, vol.298
, pp. 789-791
-
-
Selkoe, D.J.1
-
13
-
-
5344272541
-
A focus on the synapse for neuroprotection in Alzheimer disease and other dementias
-
Coleman P, Federoff H, Kurlan R (2004) A focus on the synapse for neuroprotection in Alzheimer disease and other dementias. Neurology 63, 1155-1162.
-
(2004)
Neurology
, vol.63
, pp. 1155-1162
-
-
Coleman, P.1
Federoff, H.2
Kurlan, R.3
-
14
-
-
84880185901
-
Alzheimer's disease-related alterations in synaptic density: Neocortex and hippocampus
-
Scheff SW, Price DA (2006) Alzheimer's disease-related alterations in synaptic density: Neocortex and hippocampus. J Alzheimers Dis 9(3 Suppl), 101-115.
-
(2006)
J Alzheimers Dis
, vol.9
, Issue.3 SUPPL.
, pp. 101-115
-
-
Scheff, S.W.1
Price, D.A.2
-
15
-
-
20844458090
-
Synaptic targeting by Alzheimer's-related amyloid beta oligomers
-
Lacor PN, Buniel MC, Chang L, Fernandez SJ, Gong Y, Viola KL, LambertMP, Velasco PT, Bigio EH, Finch CE, Krafft GA, Klein WL (2004) Synaptic targeting by Alzheimer's-related amyloid beta oligomers. J Neurosci 24, 10191-10200.
-
(2004)
J Neurosci
, vol.24
, pp. 10191-10200
-
-
Lacor, P.N.1
Buniel, M.C.2
Chang, L.3
Fernandez, S.J.4
Gong, Y.5
Viola, K.L.6
Lambert, M.P.7
Velasco, P.T.8
Bigio, E.H.9
Finch, C.E.10
Krafft, G.A.11
Klein, W.L.12
-
16
-
-
81955164774
-
Preferential accumulation of amyloidbeta in presynaptic glutamatergic terminals (VGluT1 and VGluT2) in Alzheimer's disease cortex
-
Sokolow S, Luu SH, Nandy K, Miller CA, Vinters HV, Poon WW, GylysKH(2012) Preferential accumulation of amyloidbeta in presynaptic glutamatergic terminals (VGluT1 and VGluT2) in Alzheimer's disease cortex. Neurobiol Dis 45, 381-387.
-
(2012)
Neurobiol Dis
, vol.45
, pp. 381-387
-
-
Sokolow, S.1
Luu, S.H.2
Nandy, K.3
Miller, C.A.4
Vinters, H.V.5
Poon, W.W.6
Gylys, K.H.7
-
17
-
-
44549087765
-
Soluble oligomers of the amyloid betaprotein impair synaptic plasticity and behavior
-
Selkoe DJ (2008) Soluble oligomers of the amyloid betaprotein impair synaptic plasticity and behavior. Behav Brain Res 192, 106-113.
-
(2008)
Behav Brain Res
, vol.192
, pp. 106-113
-
-
Selkoe, D.J.1
-
18
-
-
0345096618
-
Structural involvement of the glutamatergic presynaptic boutons in a transgenic mouse model expressing early onset amyloid pathology
-
Bell KF, de Kort GJ, Steggerda S, Shigemoto R, Ribeiroda- Silva A, Cuello AC (2003) Structural involvement of the glutamatergic presynaptic boutons in a transgenic mouse model expressing early onset amyloid pathology. Neurosci Lett 353, 143-147.
-
(2003)
Neurosci Lett
, vol.353
, pp. 143-147
-
-
Bell, K.F.1
De Kort, G.J.2
Steggerda, S.3
Shigemoto, R.4
Ribeiroda- Silva, A.5
Cuello, A.C.6
-
19
-
-
33745920510
-
Down-regulation of vesicular glutamate transporters precedes cell loss andpathology in Alzheimer's disease
-
Kirvell SL, Esiri M, Francis PT (2006) Down-regulation of vesicular glutamate transporters precedes cell loss andpathology in Alzheimer's disease. J Neurochem 98, 939-950.
-
(2006)
J Neurochem
, vol.98
, pp. 939-950
-
-
Kirvell, S.L.1
Esiri, M.2
Francis, P.T.3
-
20
-
-
51649106793
-
Loss of VGLUT1 and VGLUT2 in the prefrontal cortex is correlated with cognitive decline in Alzheimer disease
-
Kashani A, Lepicard E, Poirel O, Videau C, David JP, Fallet- Bianco C, Simon A, Delacourte A, Giros B, Epelbaum J, Betancur C, El Mestikawy S (2008) Loss of VGLUT1 and VGLUT2 in the prefrontal cortex is correlated with cognitive decline in Alzheimer disease. Neurobiol Aging 29, 1619-1630.
-
(2008)
Neurobiol Aging
, vol.29
, pp. 1619-1630
-
-
Kashani, A.1
Lepicard, E.2
Poirel, O.3
Videau, C.4
David, J.P.5
Fallet- Bianco, C.6
Simon, A.7
Delacourte, A.8
Giros, B.9
Epelbaum, J.10
Betancur, C.11
El Mestikawy, S.12
-
21
-
-
84886592954
-
Predominant loss of glutamatergic terminal markers in a -amyloid peptide model of Alzheimer's disease
-
Canas PM, Simões AP, Rodrigues RJ, Cunha RA (2014) Predominant loss of glutamatergic terminal markers in a -amyloid peptide model of Alzheimer's disease. Neuropharmacology 76, 51-56.
-
(2014)
Neuropharmacology
, vol.76
, pp. 51-56
-
-
Canas, P.M.1
Simões, A.P.2
Rodrigues, R.J.3
Cunha, R.A.4
-
22
-
-
0142106470
-
Subcellular localization of adenosine A1 receptors in nerve terminals and synapses of the rat hippocampus
-
Rebola N, Pinheiro PC, Oliveira CR, Malva JO, Cunha RA (2003) Subcellular localization of adenosine A1 receptors in nerve terminals and synapses of the rat hippocampus. Brain Res 987, 49-58.
-
(2003)
Brain Res
, vol.987
, pp. 49-58
-
-
Rebola, N.1
Pinheiro, P.C.2
Oliveira, C.R.3
Malva, J.O.4
Cunha, R.A.5
-
23
-
-
17944375149
-
The presynaptic particle web: Ultrastructure, composition, dissolution, and reconstitution
-
Phillips GR, Huang JK, Wang Y, Tanaka H, Shapiro L, Zhang W, Shan WS, Arndt K, Frank M, Gordon RE, Gawinowicz MA, Zhao Y, Colman DR (2001) The presynaptic particle web: Ultrastructure, composition, dissolution, and reconstitution. Neuron 32, 63-77.
-
(2001)
Neuron
, vol.32
, pp. 63-77
-
-
Phillips, G.R.1
Huang, J.K.2
Wang, Y.3
Tanaka, H.4
Shapiro, L.5
Zhang, W.6
Shan, W.S.7
Arndt, K.8
Frank, M.9
Gordon, R.E.10
Gawinowicz, M.A.11
Zhao, Y.12
Colman, D.R.13
-
24
-
-
84862776724
-
Adenosine A2A receptors modulate glutamate uptake in cultured astrocytes and gliosomes
-
Matos M, Augusto E, Santos-Rodrigues A, Schwarzschild MA, Chen J-F, Cunha RA, Agostinho P (2012) Adenosine A2A receptors modulate glutamate uptake in cultured astrocytes and gliosomes. Glia 60, 702-716.
-
(2012)
Glia
, vol.60
, pp. 702-716
-
-
Matos, M.1
Augusto, E.2
Santos-Rodrigues, A.3
Schwarzschild, M.A.4
Chen, J.-F.5
Cunha, R.A.6
Agostinho, P.7
-
25
-
-
58749107499
-
A rapid Percoll gradient procedure for preparation of synaptosomes
-
Dunkley PR, Jarvie PE, Robinson PJ (2008) A rapid Percoll gradient procedure for preparation of synaptosomes. Nat Protoc 3, 1718-1728.
-
(2008)
Nat Protoc
, vol.3
, pp. 1718-1728
-
-
Dunkley, P.R.1
Jarvie, P.E.2
Robinson, P.J.3
-
26
-
-
21844443354
-
Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus
-
Rodrigues RJ, Almeida T, Richardson PJ, Oliveira CR, Cunha RA (2005) Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus. J Neurosci 25, 6286-6295.
-
(2005)
J Neurosci
, vol.25
, pp. 6286-6295
-
-
Rodrigues, R.J.1
Almeida, T.2
Richardson, P.J.3
Oliveira, C.R.4
Cunha, R.A.5
-
27
-
-
72449208698
-
Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by -amyloid peptides via p38 mitogen-activated protein kinase pathway
-
Canas PM, Porciúncula LO, CunhaGMA, Silva CG, Machado NJ, Oliveira JM, Oliveira CR, Cunha RA (2009) Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by -amyloid peptides via p38 mitogen-activated protein kinase pathway. J Neurosci 29, 14741-14751.
-
(2009)
J Neurosci
, vol.29
, pp. 14741-14751
-
-
Canas, P.M.1
Porciúncula, L.O.2
Cunha, G.M.A.3
Silva, C.G.4
Machado, N.J.5
Oliveira, J.M.6
Oliveira, C.R.7
Cunha, R.A.8
-
28
-
-
79952548073
-
Adenosine A2A receptors control neuroinflammation and consequent hippocampal neuronal dysfunction
-
Rebola N, Simões AP, Canas PM, Tomé AR, Andrade GM, Barry CE, Agostinho PM, Lynch MA, Cunha RA (2011) Adenosine A2A receptors control neuroinflammation and consequent hippocampal neuronal dysfunction. J Neurochem 117, 100-111.
-
(2011)
J Neurochem
, vol.117
, pp. 100-111
-
-
Rebola, N.1
Simões, A.P.2
Canas, P.M.3
Tomé, A.R.4
Andrade, G.M.5
Barry, C.E.6
Agostinho, P.M.7
Lynch, M.A.8
Cunha, R.A.9
-
29
-
-
0031780158
-
Synapses in hippocampus occupy only 1-2% of cell membranes and are spaced less than half-micron apart: A quantitative ultrastructural analysis with discussion of physiological implications
-
Rusakov DA, Harrison E, Stewart MG (1998) Synapses in hippocampus occupy only 1-2% of cell membranes and are spaced less than half-micron apart: A quantitative ultrastructural analysis with discussion of physiological implications. Neuropharmacology 37, 513-521.
-
(1998)
Neuropharmacology
, vol.37
, pp. 513-521
-
-
Rusakov, D.A.1
Harrison, E.2
Stewart, M.G.3
-
30
-
-
70349569016
-
Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate (-secretase activity
-
Kim M, Suh J, Romano D, Truong MH, Mullin K, Hooli B, Norton D, Tesco G, Elliott K, Wagner SL, Moir RD, Becker KD, Tanzi RE (2009) Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate (-secretase activity. Hum Mol Genet 18, 3987-3996.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 3987-3996
-
-
Kim, M.1
Suh, J.2
Romano, D.3
Truong, M.H.4
Mullin, K.5
Hooli, B.6
Norton, D.7
Tesco, G.8
Elliott, K.9
Wagner, S.L.10
Moir, R.D.11
Becker, K.D.12
Tanzi, R.E.13
-
31
-
-
84860869183
-
APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms
-
Isbert S, Wagner K, Eggert S, Schweitzer A, Multhaup G, Weggen S, Kins S, Pietrzik CU (2012) APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms. Cell Mol Life Sci 69, 1353-1375.
-
(2012)
Cell Mol Life Sci
, vol.69
, pp. 1353-1375
-
-
Isbert, S.1
Wagner, K.2
Eggert, S.3
Schweitzer, A.4
Multhaup, G.5
Weggen, S.6
Kins, S.7
Pietrzik, C.U.8
-
32
-
-
16344384157
-
Adenosine A1 and A2A receptors are co-expressed in pyramidal neurons and co-localized in glutamatergic nerve terminals of the rat hippocampus
-
Rebola N, Rodrigues RJ, Lopes LV, Richardson PJ, Oliveira CR, Cunha RA (2005) Adenosine A1 and A2A receptors are co-expressed in pyramidal neurons and co-localized in glutamatergic nerve terminals of the rat hippocampus. Neuroscience 133, 79-83.
-
(2005)
Neuroscience
, vol.133
, pp. 79-83
-
-
Rebola, N.1
Rodrigues, R.J.2
Lopes, L.V.3
Richardson, P.J.4
Oliveira, C.R.5
Cunha, R.A.6
-
33
-
-
15244356828
-
Involvement of cannabinoid receptors in the regulation of neurotransmitter release in the rodent striatum: A combined immunochemical and pharmacological analysis
-
Köfalvi A, Rodrigues RJ, Ledent C, Mackie K, Vizi ES, Cunha RA, Sperlágh B (2005) Involvement of cannabinoid receptors in the regulation of neurotransmitter release in the rodent striatum: A combined immunochemical and pharmacological analysis. J Neurosci 25, 2874-2884.
-
(2005)
J Neurosci
, vol.25
, pp. 2874-2884
-
-
Köfalvi, A.1
Rodrigues, R.J.2
Ledent, C.3
Mackie, K.4
Vizi, E.S.5
Cunha, R.A.6
Sperlágh, B.7
-
34
-
-
33748938381
-
CB1 receptor antagonism increases hippocampal acetylcholine release: Site and mechanism of action
-
Degroot A, Köfalvi A, Wade MR, Davis RJ, Rodrigues RJ, Rebola N, Cunha RA, Nomikos GG (2006) CB1 receptor antagonism increases hippocampal acetylcholine release: Site and mechanism of action. Mol Pharmacol 70, 1236-1245.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1236-1245
-
-
Degroot, A.1
Köfalvi, A.2
Wade, M.R.3
Davis, R.J.4
Rodrigues, R.J.5
Rebola, N.6
Cunha, R.A.7
Nomikos, G.G.8
-
35
-
-
49349116847
-
Modification of adenosine receptor modulation of acetylcholine release in the hippocampus of aged rats
-
Rodrigues RJ, Canas PM, Lopes LV, Oliveira CR, Cunha RA (2008) Modification of adenosine receptor modulation of acetylcholine release in the hippocampus of aged rats. Neurobiol Aging 29, 1597-1601.
-
(2008)
Neurobiol Aging
, vol.29
, pp. 1597-1601
-
-
Rodrigues, R.J.1
Canas, P.M.2
Lopes, L.V.3
Oliveira, C.R.4
Cunha, R.A.5
-
36
-
-
65249143369
-
Subcellular localization and dimerization ofAPLP1are strikingly different fromAPPand APLP2
-
Kaden D, Voigt P, Munter LM, Bobowski KD, Schaefer M, Multhaup G (2009) Subcellular localization and dimerization ofAPLP1are strikingly different fromAPPand APLP2. J Cell Sci 122, 368-377.
-
(2009)
J Cell Sci
, vol.122
, pp. 368-377
-
-
Kaden, D.1
Voigt, P.2
Munter, L.M.3
Bobowski, K.D.4
Schaefer, M.5
Multhaup, G.6
-
37
-
-
0025978820
-
Amyloid precursor protein in aged nonhuman primates
-
Martin LJ, Sisodia SS, Koo EH, Cork LC, Dellovade TL, Weidemann A, Beyreuther K, Masters C, Price DL (1991) Amyloid precursor protein in aged nonhuman primates. Proc Natl Acad Sci U S A 88, 1461-1465.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 1461-1465
-
-
Martin, L.J.1
Sisodia, S.S.2
Koo, E.H.3
Cork, L.C.4
Dellovade, T.L.5
Weidemann, A.6
Beyreuther, K.7
Masters, C.8
Price, D.L.9
-
38
-
-
69749115919
-
Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis
-
Wang Z, Wang B, Yang L, Guo Q, Aithmitti N, Songyang Z, Zheng H (2009) Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis. J Neurosci 29, 10788-10801.
-
(2009)
J Neurosci
, vol.29
, pp. 10788-10801
-
-
Wang, Z.1
Wang, B.2
Yang, L.3
Guo, Q.4
Aithmitti, N.5
Songyang, Z.6
Zheng, H.7
-
39
-
-
79957909084
-
APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP
-
Weyer SW, Klevanski M, Delekate A, Voikar V, Aydin D, Hick M, FilippovM, Drost N, Schaller KL, Saar M, Vogt MA, Gass P, Samanta A, Jaschke A, Korte M, Wolfer DP, Caldwell JH, Muller UC (2011) APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP. EMBO J 30, 2266-2280.
-
(2011)
EMBO J
, vol.30
, pp. 2266-2280
-
-
Weyer, S.W.1
Klevanski, M.2
Delekate, A.3
Voikar, V.4
Aydin, D.5
Hick, M.6
Filippov, M.7
Drost, N.8
Schaller, K.L.9
Saar, M.10
Vogt, M.A.11
Gass, P.12
Samanta, A.13
Jaschke, A.14
Korte, M.15
Wolfer, D.P.16
Caldwell, J.H.17
Muller, U.C.18
-
40
-
-
0028323567
-
Differential distribution of amyloid protein precursor immunoreactivity in the rat brain studied by using five different antibodies
-
Beeson JG, Shelton ER, Chan HW, Gage FH (1994) Differential distribution of amyloid protein precursor immunoreactivity in the rat brain studied by using five different antibodies. J Comp Neurol 342, 78-96.
-
(1994)
J Comp Neurol
, vol.342
, pp. 78-96
-
-
Beeson, J.G.1
Shelton, E.R.2
Chan, H.W.3
Gage, F.H.4
-
41
-
-
84862837302
-
Role of APP for dendritic spine formation and stability
-
Jung CK, Herms J (2012) Role of APP for dendritic spine formation and stability. Exp Brain Res 217, 463-470.
-
(2012)
Exp Brain Res
, vol.217
, pp. 463-470
-
-
Jung, C.K.1
Herms, J.2
-
42
-
-
0026784096
-
Localization of amyloid precursor protein in selective postsynaptic densities of rat cortical neurons
-
Shigematsu K, McGeer PL, McGeer EG (1992) Localization of amyloid precursor protein in selective postsynaptic densities of rat cortical neurons. Brain Res 592, 353-357.
-
(1992)
Brain Res
, vol.592
, pp. 353-357
-
-
Shigematsu, K.1
McGeer, P.L.2
McGeer, E.G.3
-
43
-
-
0141462295
-
The amyloid precursor protein of Alzheimer's disease is found on the surface of static but not activity motile portions of neurites
-
Storey E, Spurck T, Pickett-Heaps J, Beyreuther K, Masters CL (1996) The amyloid precursor protein of Alzheimer's disease is found on the surface of static but not activity motile portions of neurites. Brain Res 735, 59-66.
-
(1996)
Brain Res
, vol.735
, pp. 59-66
-
-
Storey, E.1
Spurck, T.2
Pickett-Heaps, J.3
Beyreuther, K.4
Masters, C.L.5
-
44
-
-
79955695654
-
Amyloid precursor protein is trafficked and secreted via synaptic vesicles
-
Groemer TW, Thiel CS, Holt M, Riedel D, Hua Y, Hüve J, Wilhelm BG, Klingauf J (2011) Amyloid precursor protein is trafficked and secreted via synaptic vesicles. PLoS One 6, e18754
-
(2011)
PLoS One
, vol.6
-
-
Groemer, T.W.1
Thiel, C.S.2
Holt, M.3
Riedel, D.4
Hua, Y.5
Hüve, J.6
Wilhelm, B.G.7
Klingauf, J.8
-
45
-
-
0032939003
-
Amyloid precursor protein of Alzheimer's disease: Evidence for a stable, full-length, trans-membrane pool in primary neuronal cultures
-
Storey E, Katz M, Brickman Y, Beyreuther K, Masters CL (1999) Amyloid precursor protein of Alzheimer's disease: Evidence for a stable, full-length, trans-membrane pool in primary neuronal cultures. Eur J Neurosci 11, 1779-1788.
-
(1999)
Eur J Neurosci
, vol.11
, pp. 1779-1788
-
-
Storey, E.1
Katz, M.2
Brickman, Y.3
Beyreuther, K.4
Masters, C.L.5
-
46
-
-
33746233383
-
Synapse formation and function is modulated by the amyloid precursor protein
-
Priller C, Bauer T, Mitteregger G, Krebs B, Kretzschmar HA, Herms J (2006) Synapse formation and function is modulated by the amyloid precursor protein. J Neurosci 26, 7212-7221.
-
(2006)
J Neurosci
, vol.26
, pp. 7212-7221
-
-
Priller, C.1
Bauer, T.2
Mitteregger, G.3
Krebs, B.4
Kretzschmar, H.A.5
Herms, J.6
-
47
-
-
58849151716
-
Synaptic retrogenesis and amyloid-beta in Alzheimer's disease
-
Wasling P, Daborg J, Riebe I, Andersson M, Portelius E, Blennow K, Hanse E, Zetterberg H (2009) Synaptic retrogenesis and amyloid-beta in Alzheimer's disease. J Alzheimers Dis 16, 1-14.
-
(2009)
J Alzheimers Dis
, vol.16
, pp. 1-14
-
-
Wasling, P.1
Daborg, J.2
Riebe, I.3
Andersson, M.4
Portelius, E.5
Blennow, K.6
Hanse, E.7
Zetterberg, H.8
-
48
-
-
77953810503
-
Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines
-
Lee KJ, Moussa CE, Lee Y, Sung Y, Howell BW, Turner RS, Pak DT, Hoe HS (2010) Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines. Neuroscience 169, 344-356.
-
(2010)
Neuroscience
, vol.169
, pp. 344-356
-
-
Lee, K.J.1
Moussa, C.E.2
Lee, Y.3
Sung, Y.4
Howell, B.W.5
Turner, R.S.6
Pak, D.T.7
Hoe, H.S.8
-
49
-
-
35348889638
-
Amyolid precursor protein mediates presynaptic localization and activity of the high-affinity choline transporter
-
Wang B, Yang L, Wang Z, ZhengH(2007) Amyolid precursor protein mediates presynaptic localization and activity of the high-affinity choline transporter. Proc Natl Acad Sci U S A 104, 14140-14145.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 14140-14145
-
-
Wang, B.1
Yang, L.2
Wang, Z.3
Zheng, H.4
-
50
-
-
41549155927
-
Endocytosis is required for synaptic activity-dependent release of amyloidbeta in vivo
-
Cirrito JR, Kang JE, Lee J, Stewart FR, Verges DK, Silverio LM, BuG, Mennerick S, HoltzmanDM(2008) Endocytosis is required for synaptic activity-dependent release of amyloidbeta in vivo. Neuron 58, 42-51.
-
(2008)
Neuron
, vol.58
, pp. 42-51
-
-
Cirrito, J.R.1
Kang, J.E.2
Lee, J.3
Stewart, F.R.4
Verges, D.K.5
Silverio, L.M.6
Bu, G.7
Mennerick, S.8
Holtzman, D.M.9
-
51
-
-
79961228576
-
Opposing synaptic regulation of amyloid- metabolism by NMDA receptors in vivo
-
Verges DK, Restivo JL, Goebel WD, Holtzman DM, Cirrito JR (2011) Opposing synaptic regulation of amyloid- metabolism by NMDA receptors in vivo. J Neurosci 31, 11328-11337.
-
(2011)
J Neurosci
, vol.31
, pp. 11328-11337
-
-
Verges, D.K.1
Restivo, J.L.2
Goebel, W.D.3
Holtzman, D.M.4
Cirrito, J.R.5
-
52
-
-
84878556106
-
Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer's disease
-
Marcello E, Saraceno C, Musardo S, Vara H, de la FuenteAG, Pelucchi S, Di Marino D, Borroni B, Tramontano A, Pérez- Otaño I, Padovani A, Giustetto M, Gardoni F, Di Luca M (2013) Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer's disease. J Clin Invest 123, 2523-2538.
-
(2013)
J Clin Invest
, vol.123
, pp. 2523-2538
-
-
Marcello, E.1
Saraceno, C.2
Musardo, S.3
Vara, H.4
De La Fuente, A.G.5
Pelucchi, S.6
Di Marino, D.7
Borroni, B.8
Tramontano, A.9
Pérez-Otaño, I.10
Padovani, A.11
Giustetto, M.12
Gardoni, F.13
Di Luca, M.14
-
53
-
-
77952519104
-
Synaptic and endosomal localization of active gamma-secretase in rat brain
-
Frykman S, Hur JY, Frånberg J, Aoki M, Winblad B, Nahalkova J, Behbahani H, Tjernberg LO (2010) Synaptic and endosomal localization of active gamma-secretase in rat brain. PLOS One 5, e8948.
-
(2010)
PLOS One
, vol.5
-
-
Frykman, S.1
Hur, J.Y.2
Frånberg, J.3
Aoki, M.4
Winblad, B.5
Nahalkova, J.6
Behbahani, H.7
Tjernberg, L.O.8
-
54
-
-
67649776586
-
The effects of amyloid precursor protein on postsynaptic composition and activity
-
Hoe HS, Fu Z, Makarova A, Lee JY, Lu C, Feng L, Pajoohesh- Ganji A, Matsuoka Y, Hyman BT, Ehlers MD, Vicini S, Pak DT, RebeckGW(2009) The effects of amyloid precursor protein on postsynaptic composition and activity. J Biol Chem 284, 8495-8506.
-
(2009)
J Biol Chem
, vol.284
, pp. 8495-8506
-
-
Hoe, H.S.1
Fu, Z.2
Makarova, A.3
Lee, J.Y.4
Lu, C.5
Feng, L.6
Pajoohesh- Ganji, A.7
Matsuoka, Y.8
Hyman, B.T.9
Ehlers, M.D.10
Vicini, S.11
Pak, D.T.12
Rebeck, G.W.13
-
55
-
-
84884904327
-
Amyloid precursor proteins are constituents of the presynaptic active zone
-
Laßek M, Weingarten J, Einsfelder U, Brendel P, Müller U, Volknandt W (2013) Amyloid precursor proteins are constituents of the presynaptic active zone. J Neurochem 127, 48-56.
-
(2013)
J Neurochem
, vol.127
, pp. 48-56
-
-
Laßek, M.1
Weingarten, J.2
Einsfelder, U.3
Brendel, P.4
Müller, U.5
Volknandt, W.6
-
56
-
-
0035830408
-
Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease
-
Masliah E, Mallory M, Alford M, DeTeresa R, Hansen LA, McKeel DW, Jr., Morris JC (2001) Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease. Neurology 56, 127-129.
-
(2001)
Neurology
, vol.56
, pp. 127-129
-
-
Masliah, E.1
Mallory, M.2
Alford, M.3
Deteresa, R.4
Hansen, L.A.5
McKeel Jr., D.W.6
Morris, J.C.7
-
57
-
-
84879966026
-
From synaptic spines to nuclear signaling: Nuclear and synaptic actions of the amyloid precursor protein
-
Octave JN, Pierrot N, Ferao Santos S, Nalivaeva NN, Turner AJ (2013) From synaptic spines to nuclear signaling: Nuclear and synaptic actions of the amyloid precursor protein. J Neurochem 126, 183-190.
-
(2013)
J Neurochem
, vol.126
, pp. 183-190
-
-
Octave, J.N.1
Pierrot, N.2
Ferao Santos, S.3
Nalivaeva, N.N.4
Turner, A.J.5
-
58
-
-
85027929889
-
A oligomerinduced synapse degeneration in Alzheimer's disease
-
Wilcox KC, Lacor PN, Pitt J, Klein WL (2011) A oligomerinduced synapse degeneration in Alzheimer's disease. Cell Mol Neurobiol 31, 939-948.
-
(2011)
Cell Mol Neurobiol
, vol.31
, pp. 939-948
-
-
Wilcox, K.C.1
Lacor, P.N.2
Pitt, J.3
Klein, W.L.4
-
59
-
-
84879979361
-
Deregulation of excitatory neurotransmission underlying synapse failure in Alzheimer's disease
-
Paula-Lima AC, Brito-Moreira J, Ferreira ST (2013) Deregulation of excitatory neurotransmission underlying synapse failure in Alzheimer's disease. J Neurochem 126, 191-202.
-
(2013)
J Neurochem
, vol.126
, pp. 191-202
-
-
Paula-Lima, A.C.1
Brito-Moreira, J.2
Ferreira, S.T.3
-
60
-
-
67650079550
-
Glutamate release from astrocytic gliosomes under physiological and pathological conditions
-
Milanese M, Bonifacino T, Zappettini S, Usai C, Tacchetti C, Nobile M, Bonanno G (2009) Glutamate release from astrocytic gliosomes under physiological and pathological conditions. Int Rev Neurobiol 85, 295-318.
-
(2009)
Int Rev Neurobiol
, vol.85
, pp. 295-318
-
-
Milanese, M.1
Bonifacino, T.2
Zappettini, S.3
Usai, C.4
Tacchetti, C.5
Nobile, M.6
Bonanno, G.7
-
61
-
-
84865592766
-
Astrocytic adenosine A2A receptors control the amyloid peptide-induced decrease of glutamate uptake
-
Matos M, Augusto E, Machado NJ, dos Santos-Rodrigues A, Cunha RA, Agostinho P (2012) Astrocytic adenosine A2A receptors control the amyloid peptide-induced decrease of glutamate uptake. J Alzheimers Dis 31, 555-567.
-
(2012)
J Alzheimers Dis
, vol.31
, pp. 555-567
-
-
Matos, M.1
Augusto, E.2
Machado, N.J.3
Dos Santos-Rodrigues, A.4
Cunha, R.A.5
Agostinho, P.6
-
62
-
-
0026325645
-
Processing of betaamyloid precursor protein in microglia and astrocytes favors an internal localization over constitutive secretion
-
Haass C, Hung AY, Selkoe DJ (1991) Processing of betaamyloid precursor protein in microglia and astrocytes favors an internal localization over constitutive secretion. J Neurosci 11, 3783-3793.
-
(1991)
J Neurosci
, vol.11
, pp. 3783-3793
-
-
Haass, C.1
Hung, A.Y.2
Selkoe, D.J.3
-
63
-
-
79955855980
-
Glial amyloid precursor protein expression is restricted to astrocytes in an experimental toxic model of multiple sclerosis
-
Clarner T, Buschmann JP, Beyer C, KippM(2011) Glial amyloid precursor protein expression is restricted to astrocytes in an experimental toxic model of multiple sclerosis. J Mol Neurosci 4, 268-274.
-
(2011)
J Mol Neurosci
, vol.4
, pp. 268-274
-
-
Clarner, T.1
Buschmann, J.P.2
Beyer, C.3
Kipp, M.4
-
64
-
-
0026486606
-
Ultrastructural localization of Alzheimer amyloid beta/A4 protein precursor in the cytoplasm of neurons and senile plaque-associated astrocytes
-
Yamaguchi H, Yamazaki T, Ishiguro K, Shoji M, Nakazato Y, Hirai S (1992) Ultrastructural localization of Alzheimer amyloid beta/A4 protein precursor in the cytoplasm of neurons and senile plaque-associated astrocytes. Acta Neuropathol 85, 15-22.
-
(1992)
Acta Neuropathol
, vol.85
, pp. 15-22
-
-
Yamaguchi, H.1
Yamazaki, T.2
Ishiguro, K.3
Shoji, M.4
Nakazato, Y.5
Hirai, S.6
-
65
-
-
67249087641
-
Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake
-
Li S, Hong S, Shepardson NE, Walsh DM, Shankar GM, Selkoe D (2009) Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake. Neuron 62, 788-801.
-
(2009)
Neuron
, vol.62
, pp. 788-801
-
-
Li, S.1
Hong, S.2
Shepardson, N.E.3
Walsh, D.M.4
Shankar, G.M.5
Selkoe, D.6
-
66
-
-
84877089562
-
Amyloid 1-42 slows clearance of synaptically released glutamate by mislocalizing astrocytic GLT-1
-
Scimemi A, Meabon JS, Woltjer RL, Sullivan JM, Diamond JS, Cook DG (2013) Amyloid 1-42 slows clearance of synaptically released glutamate by mislocalizing astrocytic GLT-1. J Neurosci 33, 5312-5318.
-
(2013)
J Neurosci
, vol.33
, pp. 5312-5318
-
-
Scimemi, A.1
Meabon, J.S.2
Woltjer, R.L.3
Sullivan, J.M.4
Diamond, J.S.5
Cook, D.G.6
-
67
-
-
84879732252
-
A induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss
-
Talantova M, Sanz-Blasco S, Zhang X, Xia P, Akhtar MW, Okamoto S, Dziewczapolski G, Nakamura T, Cao G, Pratt AE, Kang YJ, Tu S, Molokanova E, McKercher SR, Hires SA, Sason H, Stouffer DG, BuczynskiMW, Solomon JP, Michael S, Powers ET, Kelly JW, Roberts A, Tong G, Fang-Newmeyer T, Parker J, Holland EA, Zhang D, Nakanishi N, Chen HS, Wolosker H, Wang Y, Parsons LH, Ambasudhan R, Masliah E, Heinemann SF, Piña-Crespo JC, Lipton SA (2013) A induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss. Proc Natl Acad Sci U S A 110, E2518-E2527.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
-
-
Talantova, M.1
Sanz-Blasco, S.2
Zhang, X.3
Xia, P.4
Akhtar, M.W.5
Okamoto, S.6
Dziewczapolski, G.7
Nakamura, T.8
Cao, G.9
Pratt, A.E.10
Kang, Y.J.11
Tu, S.12
Molokanova, E.13
McKercher, S.R.14
Hires, S.A.15
Sason, H.16
Stouffer, D.G.17
Buczynski, M.W.18
Solomon, J.P.19
Michael, S.20
Powers, E.T.21
Kelly, J.W.22
Roberts, A.23
Tong, G.24
Fang-Newmeyer, T.25
Parker, J.26
Holland, E.A.27
Zhang, D.28
Nakanishi, N.29
Chen, H.S.30
Wolosker, H.31
Wang, Y.32
Parsons, L.H.33
Ambasudhan, R.34
Masliah, E.35
Heinemann, S.F.36
Piña-Crespo, J.C.37
Lipton, S.A.38
more..
-
68
-
-
33847725506
-
Alterations in expression of glutamatergic transporters and receptors in sporadic Alzheimer's disease
-
Jacob CP, Koutsilieri E, Bartl J, Neuen-Jacob E, Arzberger T, Zander N, Ravid R, Roggendorf W, Riederer P, Grunblatt E (2007) Alterations in expression of glutamatergic transporters and receptors in sporadic Alzheimer's disease. J Alzheimers Dis 11, 97-116.
-
(2007)
J Alzheimers Dis
, vol.11
, pp. 97-116
-
-
Jacob, C.P.1
Koutsilieri, E.2
Bartl, J.3
Neuen-Jacob, E.4
Arzberger, T.5
Zander, N.6
Ravid, R.7
Roggendorf, W.8
Riederer, P.9
Grunblatt, E.10
-
69
-
-
0029794266
-
Expression and distribution of amyloid precursor protein-like protein-2 in Alzheimer's disease and in normal brain
-
Crain BJ, Hu W, Sze CI, Slunt HH, Koo EH, Price DL, Thinakaran G, Sisodia SS (1996) Expression and distribution of amyloid precursor protein-like protein-2 in Alzheimer's disease and in normal brain. Am J Pathol 149, 1087-1095.
-
(1996)
Am J Pathol
, vol.149
, pp. 1087-1095
-
-
Crain, B.J.1
Hu, W.2
Sze, C.I.3
Slunt, H.H.4
Koo, E.H.5
Price, D.L.6
Thinakaran, G.7
Sisodia, S.S.8
-
70
-
-
80053566644
-
FE65 proteins regulate NMDA receptor activation-induced amyloid precursor protein processing
-
Suh J, Lyckman A, Wang L, Eckman EA, Guénette SY (2011) FE65 proteins regulate NMDA receptor activation-induced amyloid precursor protein processing. J Neurochem 119, 377-388.
-
(2011)
J Neurochem
, vol.119
, pp. 377-388
-
-
Suh, J.1
Lyckman, A.2
Wang, L.3
Eckman, E.A.4
Guénette, S.Y.5
-
71
-
-
78650669822
-
The transcriptionally active amyloid precursor protein (APP) intracellular domain is preferentially produced from the 695 isoform of APP in a {beta}-secretase-dependent pathway
-
Belyaev ND, Kellett KA, Beckett C, Makova NZ, Revett TJ, Nalivaeva NN, Hooper NM, Turner AJ (2010) The transcriptionally active amyloid precursor protein (APP) intracellular domain is preferentially produced from the 695 isoform of APP in a {beta}-secretase-dependent pathway. J Biol Chem 285, 41443-41454.
-
(2010)
J Biol Chem
, vol.285
, pp. 41443-41454
-
-
Belyaev, N.D.1
Kellett, K.A.2
Beckett, C.3
Makova, N.Z.4
Revett, T.J.5
Nalivaeva, N.N.6
Hooper, N.M.7
Turner, A.J.8
-
72
-
-
80053918665
-
Soluble amyloid precursor protein: A novel proliferation factor of adult progenitor cells of ectodermal and mesodermal origin
-
Demars MP, Bartholomew A, Strakova Z, Lazarov O (2011) Soluble amyloid precursor protein: A novel proliferation factor of adult progenitor cells of ectodermal and mesodermal origin. Stem Cell Res Ther 2, 36-51. Nível Superior
-
(2011)
Stem Cell Res Ther
, vol.2
, pp. 36-51
-
-
Demars, M.P.1
Bartholomew, A.2
Strakova, Z.3
Lazarov, O.4
|