메뉴 건너뛰기




Volumn 40, Issue 4, 2014, Pages 981-992

Synaptic and sub-synaptic localization of amyloid-β protein precursor in the rat hippocampus

Author keywords

Alzheimer's disease; amyloid protein precursor; gliosomes; nerve terminals; sub synaptic fractions; synaptosomes

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CHOLINERGIC RECEPTOR STIMULATING AGENT; EPITOPE; VESICULAR GLUTAMATE TRANSPORTER 1; VESICULAR INHIBITORY AMINO ACID TRANSPORTER; GLUCOSE TRANSPORTER 1; SLC2A1 PROTEIN, RAT; VESICULAR ACETYLCHOLINE TRANSPORTER;

EID: 84901755722     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-132030     Document Type: Article
Times cited : (19)

References (72)
  • 1
    • 0042634362 scopus 로고    scopus 로고
    • Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory
    • Turner PR, O'Connor K, TateWP, AbrahamWC(2003) Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory. Prog Neurobiol 70, 1-32.
    • (2003) Prog Neurobiol , vol.70 , pp. 1-32
    • Turner, P.R.1    O'connor, K.2    Tate, W.P.3    Abraham, W.C.4
  • 2
    • 33750151421 scopus 로고    scopus 로고
    • Subcellular trafficking of the amyloid precursor protein gene family and its pathogenic role in Alzheimer's disease
    • Kins S, Lauther N, Szodorai A, Beyreuther K (2006) Subcellular trafficking of the amyloid precursor protein gene family and its pathogenic role in Alzheimer's disease. Neurodegener Dis 3, 218-226.
    • (2006) Neurodegener Dis , vol.3 , pp. 218-226
    • Kins, S.1    Lauther, N.2    Szodorai, A.3    Beyreuther, K.4
  • 3
    • 33750151420 scopus 로고    scopus 로고
    • The functions of mammalian amyloid precursor protein and related amyloid precursor-like proteins
    • Anliker B, Müller U (2006) The functions of mammalian amyloid precursor protein and related amyloid precursor-like proteins. Neurodegener Dis 3, 239-246.
    • (2006) Neurodegener Dis , vol.3 , pp. 239-246
    • Anliker, B.1    Müller, U.2
  • 4
    • 84861721553 scopus 로고    scopus 로고
    • Functions of the APP gene family in the nervous system: Insights from mouse models
    • Aydin D, Weyer SW, Müller UC (2012) Functions of the APP gene family in the nervous system: Insights from mouse models. Exp Brain Res 217, 423-434.
    • (2012) Exp Brain Res , vol.217 , pp. 423-434
    • Aydin, D.1    Weyer, S.W.2    Müller, U.C.3
  • 5
    • 84862837302 scopus 로고    scopus 로고
    • Role of APP for dendritic spine formation and stability
    • Jung CK, Herms J (2012) Role of APP for dendritic spine formation and stability. Exp Brain Res 217, 463-470.
    • (2012) Exp Brain Res , vol.217 , pp. 463-470
    • Jung, C.K.1    Herms, J.2
  • 6
    • 84862838270 scopus 로고    scopus 로고
    • The role of APP and APLP for synaptic transmission, plasticity, and network function: Lessons from genetic mouse models
    • Korte M, Herrmann U, Zhang X, Draguhn A (2012) The role of APP and APLP for synaptic transmission, plasticity, and network function: Lessons from genetic mouse models. Exp Brain Res 217, 435-440.
    • (2012) Exp Brain Res , vol.217 , pp. 435-440
    • Korte, M.1    Herrmann, U.2    Zhang, X.3    Draguhn, A.4
  • 8
    • 84655160766 scopus 로고    scopus 로고
    • Proteolytic processing of Alzheimer's -amyloid precursor protein
    • Zhang H, Ma Q, ZhangYW, XuH(2012) Proteolytic processing of Alzheimer's -amyloid precursor protein. J Neurochem 120(Suppl 1), 9-21.
    • (2012) J Neurochem , vol.120 , Issue.SUPPL. 1 , pp. 9-21
    • Zhang, H.1    Ma, Q.2    Zhang, Y.W.3    Xu, H.4
  • 9
    • 84878946078 scopus 로고    scopus 로고
    • The amyloid precursor protein: A biochemical enigma in brain development, function and disease
    • Nalivaeva NN, Turner AJ (2013) The amyloid precursor protein: A biochemical enigma in brain development, function and disease. FEBS Lett 587, 2046-2054.
    • (2013) FEBS Lett , vol.587 , pp. 2046-2054
    • Nalivaeva, N.N.1    Turner, A.J.2
  • 10
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • Hardy J, Selkoe DJ (2002) The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics. Science 297, 353-356.
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 11
    • 77954132249 scopus 로고    scopus 로고
    • Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: From synapses toward neural networks
    • Palop JJ, Mucke L (2010) Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: From synapses toward neural networks. Nat Neurosci 13, 812-818.
    • (2010) Nat Neurosci , vol.13 , pp. 812-818
    • Palop, J.J.1    Mucke, L.2
  • 12
    • 0037174618 scopus 로고    scopus 로고
    • Alzheimer's disease is a synaptic failure
    • Selkoe DJ (2002) Alzheimer's disease is a synaptic failure. Science 298, 789-791.
    • (2002) Science , vol.298 , pp. 789-791
    • Selkoe, D.J.1
  • 13
    • 5344272541 scopus 로고    scopus 로고
    • A focus on the synapse for neuroprotection in Alzheimer disease and other dementias
    • Coleman P, Federoff H, Kurlan R (2004) A focus on the synapse for neuroprotection in Alzheimer disease and other dementias. Neurology 63, 1155-1162.
    • (2004) Neurology , vol.63 , pp. 1155-1162
    • Coleman, P.1    Federoff, H.2    Kurlan, R.3
  • 14
    • 84880185901 scopus 로고    scopus 로고
    • Alzheimer's disease-related alterations in synaptic density: Neocortex and hippocampus
    • Scheff SW, Price DA (2006) Alzheimer's disease-related alterations in synaptic density: Neocortex and hippocampus. J Alzheimers Dis 9(3 Suppl), 101-115.
    • (2006) J Alzheimers Dis , vol.9 , Issue.3 SUPPL. , pp. 101-115
    • Scheff, S.W.1    Price, D.A.2
  • 16
    • 81955164774 scopus 로고    scopus 로고
    • Preferential accumulation of amyloidbeta in presynaptic glutamatergic terminals (VGluT1 and VGluT2) in Alzheimer's disease cortex
    • Sokolow S, Luu SH, Nandy K, Miller CA, Vinters HV, Poon WW, GylysKH(2012) Preferential accumulation of amyloidbeta in presynaptic glutamatergic terminals (VGluT1 and VGluT2) in Alzheimer's disease cortex. Neurobiol Dis 45, 381-387.
    • (2012) Neurobiol Dis , vol.45 , pp. 381-387
    • Sokolow, S.1    Luu, S.H.2    Nandy, K.3    Miller, C.A.4    Vinters, H.V.5    Poon, W.W.6    Gylys, K.H.7
  • 17
    • 44549087765 scopus 로고    scopus 로고
    • Soluble oligomers of the amyloid betaprotein impair synaptic plasticity and behavior
    • Selkoe DJ (2008) Soluble oligomers of the amyloid betaprotein impair synaptic plasticity and behavior. Behav Brain Res 192, 106-113.
    • (2008) Behav Brain Res , vol.192 , pp. 106-113
    • Selkoe, D.J.1
  • 18
    • 0345096618 scopus 로고    scopus 로고
    • Structural involvement of the glutamatergic presynaptic boutons in a transgenic mouse model expressing early onset amyloid pathology
    • Bell KF, de Kort GJ, Steggerda S, Shigemoto R, Ribeiroda- Silva A, Cuello AC (2003) Structural involvement of the glutamatergic presynaptic boutons in a transgenic mouse model expressing early onset amyloid pathology. Neurosci Lett 353, 143-147.
    • (2003) Neurosci Lett , vol.353 , pp. 143-147
    • Bell, K.F.1    De Kort, G.J.2    Steggerda, S.3    Shigemoto, R.4    Ribeiroda- Silva, A.5    Cuello, A.C.6
  • 19
    • 33745920510 scopus 로고    scopus 로고
    • Down-regulation of vesicular glutamate transporters precedes cell loss andpathology in Alzheimer's disease
    • Kirvell SL, Esiri M, Francis PT (2006) Down-regulation of vesicular glutamate transporters precedes cell loss andpathology in Alzheimer's disease. J Neurochem 98, 939-950.
    • (2006) J Neurochem , vol.98 , pp. 939-950
    • Kirvell, S.L.1    Esiri, M.2    Francis, P.T.3
  • 21
    • 84886592954 scopus 로고    scopus 로고
    • Predominant loss of glutamatergic terminal markers in a -amyloid peptide model of Alzheimer's disease
    • Canas PM, Simões AP, Rodrigues RJ, Cunha RA (2014) Predominant loss of glutamatergic terminal markers in a -amyloid peptide model of Alzheimer's disease. Neuropharmacology 76, 51-56.
    • (2014) Neuropharmacology , vol.76 , pp. 51-56
    • Canas, P.M.1    Simões, A.P.2    Rodrigues, R.J.3    Cunha, R.A.4
  • 22
    • 0142106470 scopus 로고    scopus 로고
    • Subcellular localization of adenosine A1 receptors in nerve terminals and synapses of the rat hippocampus
    • Rebola N, Pinheiro PC, Oliveira CR, Malva JO, Cunha RA (2003) Subcellular localization of adenosine A1 receptors in nerve terminals and synapses of the rat hippocampus. Brain Res 987, 49-58.
    • (2003) Brain Res , vol.987 , pp. 49-58
    • Rebola, N.1    Pinheiro, P.C.2    Oliveira, C.R.3    Malva, J.O.4    Cunha, R.A.5
  • 25
    • 58749107499 scopus 로고    scopus 로고
    • A rapid Percoll gradient procedure for preparation of synaptosomes
    • Dunkley PR, Jarvie PE, Robinson PJ (2008) A rapid Percoll gradient procedure for preparation of synaptosomes. Nat Protoc 3, 1718-1728.
    • (2008) Nat Protoc , vol.3 , pp. 1718-1728
    • Dunkley, P.R.1    Jarvie, P.E.2    Robinson, P.J.3
  • 26
    • 21844443354 scopus 로고    scopus 로고
    • Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus
    • Rodrigues RJ, Almeida T, Richardson PJ, Oliveira CR, Cunha RA (2005) Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus. J Neurosci 25, 6286-6295.
    • (2005) J Neurosci , vol.25 , pp. 6286-6295
    • Rodrigues, R.J.1    Almeida, T.2    Richardson, P.J.3    Oliveira, C.R.4    Cunha, R.A.5
  • 27
    • 72449208698 scopus 로고    scopus 로고
    • Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by -amyloid peptides via p38 mitogen-activated protein kinase pathway
    • Canas PM, Porciúncula LO, CunhaGMA, Silva CG, Machado NJ, Oliveira JM, Oliveira CR, Cunha RA (2009) Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by -amyloid peptides via p38 mitogen-activated protein kinase pathway. J Neurosci 29, 14741-14751.
    • (2009) J Neurosci , vol.29 , pp. 14741-14751
    • Canas, P.M.1    Porciúncula, L.O.2    Cunha, G.M.A.3    Silva, C.G.4    Machado, N.J.5    Oliveira, J.M.6    Oliveira, C.R.7    Cunha, R.A.8
  • 29
    • 0031780158 scopus 로고    scopus 로고
    • Synapses in hippocampus occupy only 1-2% of cell membranes and are spaced less than half-micron apart: A quantitative ultrastructural analysis with discussion of physiological implications
    • Rusakov DA, Harrison E, Stewart MG (1998) Synapses in hippocampus occupy only 1-2% of cell membranes and are spaced less than half-micron apart: A quantitative ultrastructural analysis with discussion of physiological implications. Neuropharmacology 37, 513-521.
    • (1998) Neuropharmacology , vol.37 , pp. 513-521
    • Rusakov, D.A.1    Harrison, E.2    Stewart, M.G.3
  • 32
    • 16344384157 scopus 로고    scopus 로고
    • Adenosine A1 and A2A receptors are co-expressed in pyramidal neurons and co-localized in glutamatergic nerve terminals of the rat hippocampus
    • Rebola N, Rodrigues RJ, Lopes LV, Richardson PJ, Oliveira CR, Cunha RA (2005) Adenosine A1 and A2A receptors are co-expressed in pyramidal neurons and co-localized in glutamatergic nerve terminals of the rat hippocampus. Neuroscience 133, 79-83.
    • (2005) Neuroscience , vol.133 , pp. 79-83
    • Rebola, N.1    Rodrigues, R.J.2    Lopes, L.V.3    Richardson, P.J.4    Oliveira, C.R.5    Cunha, R.A.6
  • 33
    • 15244356828 scopus 로고    scopus 로고
    • Involvement of cannabinoid receptors in the regulation of neurotransmitter release in the rodent striatum: A combined immunochemical and pharmacological analysis
    • Köfalvi A, Rodrigues RJ, Ledent C, Mackie K, Vizi ES, Cunha RA, Sperlágh B (2005) Involvement of cannabinoid receptors in the regulation of neurotransmitter release in the rodent striatum: A combined immunochemical and pharmacological analysis. J Neurosci 25, 2874-2884.
    • (2005) J Neurosci , vol.25 , pp. 2874-2884
    • Köfalvi, A.1    Rodrigues, R.J.2    Ledent, C.3    Mackie, K.4    Vizi, E.S.5    Cunha, R.A.6    Sperlágh, B.7
  • 35
    • 49349116847 scopus 로고    scopus 로고
    • Modification of adenosine receptor modulation of acetylcholine release in the hippocampus of aged rats
    • Rodrigues RJ, Canas PM, Lopes LV, Oliveira CR, Cunha RA (2008) Modification of adenosine receptor modulation of acetylcholine release in the hippocampus of aged rats. Neurobiol Aging 29, 1597-1601.
    • (2008) Neurobiol Aging , vol.29 , pp. 1597-1601
    • Rodrigues, R.J.1    Canas, P.M.2    Lopes, L.V.3    Oliveira, C.R.4    Cunha, R.A.5
  • 36
    • 65249143369 scopus 로고    scopus 로고
    • Subcellular localization and dimerization ofAPLP1are strikingly different fromAPPand APLP2
    • Kaden D, Voigt P, Munter LM, Bobowski KD, Schaefer M, Multhaup G (2009) Subcellular localization and dimerization ofAPLP1are strikingly different fromAPPand APLP2. J Cell Sci 122, 368-377.
    • (2009) J Cell Sci , vol.122 , pp. 368-377
    • Kaden, D.1    Voigt, P.2    Munter, L.M.3    Bobowski, K.D.4    Schaefer, M.5    Multhaup, G.6
  • 38
    • 69749115919 scopus 로고    scopus 로고
    • Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis
    • Wang Z, Wang B, Yang L, Guo Q, Aithmitti N, Songyang Z, Zheng H (2009) Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis. J Neurosci 29, 10788-10801.
    • (2009) J Neurosci , vol.29 , pp. 10788-10801
    • Wang, Z.1    Wang, B.2    Yang, L.3    Guo, Q.4    Aithmitti, N.5    Songyang, Z.6    Zheng, H.7
  • 40
    • 0028323567 scopus 로고
    • Differential distribution of amyloid protein precursor immunoreactivity in the rat brain studied by using five different antibodies
    • Beeson JG, Shelton ER, Chan HW, Gage FH (1994) Differential distribution of amyloid protein precursor immunoreactivity in the rat brain studied by using five different antibodies. J Comp Neurol 342, 78-96.
    • (1994) J Comp Neurol , vol.342 , pp. 78-96
    • Beeson, J.G.1    Shelton, E.R.2    Chan, H.W.3    Gage, F.H.4
  • 41
    • 84862837302 scopus 로고    scopus 로고
    • Role of APP for dendritic spine formation and stability
    • Jung CK, Herms J (2012) Role of APP for dendritic spine formation and stability. Exp Brain Res 217, 463-470.
    • (2012) Exp Brain Res , vol.217 , pp. 463-470
    • Jung, C.K.1    Herms, J.2
  • 42
    • 0026784096 scopus 로고
    • Localization of amyloid precursor protein in selective postsynaptic densities of rat cortical neurons
    • Shigematsu K, McGeer PL, McGeer EG (1992) Localization of amyloid precursor protein in selective postsynaptic densities of rat cortical neurons. Brain Res 592, 353-357.
    • (1992) Brain Res , vol.592 , pp. 353-357
    • Shigematsu, K.1    McGeer, P.L.2    McGeer, E.G.3
  • 43
    • 0141462295 scopus 로고    scopus 로고
    • The amyloid precursor protein of Alzheimer's disease is found on the surface of static but not activity motile portions of neurites
    • Storey E, Spurck T, Pickett-Heaps J, Beyreuther K, Masters CL (1996) The amyloid precursor protein of Alzheimer's disease is found on the surface of static but not activity motile portions of neurites. Brain Res 735, 59-66.
    • (1996) Brain Res , vol.735 , pp. 59-66
    • Storey, E.1    Spurck, T.2    Pickett-Heaps, J.3    Beyreuther, K.4    Masters, C.L.5
  • 45
    • 0032939003 scopus 로고    scopus 로고
    • Amyloid precursor protein of Alzheimer's disease: Evidence for a stable, full-length, trans-membrane pool in primary neuronal cultures
    • Storey E, Katz M, Brickman Y, Beyreuther K, Masters CL (1999) Amyloid precursor protein of Alzheimer's disease: Evidence for a stable, full-length, trans-membrane pool in primary neuronal cultures. Eur J Neurosci 11, 1779-1788.
    • (1999) Eur J Neurosci , vol.11 , pp. 1779-1788
    • Storey, E.1    Katz, M.2    Brickman, Y.3    Beyreuther, K.4    Masters, C.L.5
  • 48
    • 77953810503 scopus 로고    scopus 로고
    • Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines
    • Lee KJ, Moussa CE, Lee Y, Sung Y, Howell BW, Turner RS, Pak DT, Hoe HS (2010) Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines. Neuroscience 169, 344-356.
    • (2010) Neuroscience , vol.169 , pp. 344-356
    • Lee, K.J.1    Moussa, C.E.2    Lee, Y.3    Sung, Y.4    Howell, B.W.5    Turner, R.S.6    Pak, D.T.7    Hoe, H.S.8
  • 49
    • 35348889638 scopus 로고    scopus 로고
    • Amyolid precursor protein mediates presynaptic localization and activity of the high-affinity choline transporter
    • Wang B, Yang L, Wang Z, ZhengH(2007) Amyolid precursor protein mediates presynaptic localization and activity of the high-affinity choline transporter. Proc Natl Acad Sci U S A 104, 14140-14145.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 14140-14145
    • Wang, B.1    Yang, L.2    Wang, Z.3    Zheng, H.4
  • 51
    • 79961228576 scopus 로고    scopus 로고
    • Opposing synaptic regulation of amyloid- metabolism by NMDA receptors in vivo
    • Verges DK, Restivo JL, Goebel WD, Holtzman DM, Cirrito JR (2011) Opposing synaptic regulation of amyloid- metabolism by NMDA receptors in vivo. J Neurosci 31, 11328-11337.
    • (2011) J Neurosci , vol.31 , pp. 11328-11337
    • Verges, D.K.1    Restivo, J.L.2    Goebel, W.D.3    Holtzman, D.M.4    Cirrito, J.R.5
  • 57
    • 84879966026 scopus 로고    scopus 로고
    • From synaptic spines to nuclear signaling: Nuclear and synaptic actions of the amyloid precursor protein
    • Octave JN, Pierrot N, Ferao Santos S, Nalivaeva NN, Turner AJ (2013) From synaptic spines to nuclear signaling: Nuclear and synaptic actions of the amyloid precursor protein. J Neurochem 126, 183-190.
    • (2013) J Neurochem , vol.126 , pp. 183-190
    • Octave, J.N.1    Pierrot, N.2    Ferao Santos, S.3    Nalivaeva, N.N.4    Turner, A.J.5
  • 58
    • 85027929889 scopus 로고    scopus 로고
    • A oligomerinduced synapse degeneration in Alzheimer's disease
    • Wilcox KC, Lacor PN, Pitt J, Klein WL (2011) A oligomerinduced synapse degeneration in Alzheimer's disease. Cell Mol Neurobiol 31, 939-948.
    • (2011) Cell Mol Neurobiol , vol.31 , pp. 939-948
    • Wilcox, K.C.1    Lacor, P.N.2    Pitt, J.3    Klein, W.L.4
  • 59
    • 84879979361 scopus 로고    scopus 로고
    • Deregulation of excitatory neurotransmission underlying synapse failure in Alzheimer's disease
    • Paula-Lima AC, Brito-Moreira J, Ferreira ST (2013) Deregulation of excitatory neurotransmission underlying synapse failure in Alzheimer's disease. J Neurochem 126, 191-202.
    • (2013) J Neurochem , vol.126 , pp. 191-202
    • Paula-Lima, A.C.1    Brito-Moreira, J.2    Ferreira, S.T.3
  • 62
    • 0026325645 scopus 로고
    • Processing of betaamyloid precursor protein in microglia and astrocytes favors an internal localization over constitutive secretion
    • Haass C, Hung AY, Selkoe DJ (1991) Processing of betaamyloid precursor protein in microglia and astrocytes favors an internal localization over constitutive secretion. J Neurosci 11, 3783-3793.
    • (1991) J Neurosci , vol.11 , pp. 3783-3793
    • Haass, C.1    Hung, A.Y.2    Selkoe, D.J.3
  • 63
    • 79955855980 scopus 로고    scopus 로고
    • Glial amyloid precursor protein expression is restricted to astrocytes in an experimental toxic model of multiple sclerosis
    • Clarner T, Buschmann JP, Beyer C, KippM(2011) Glial amyloid precursor protein expression is restricted to astrocytes in an experimental toxic model of multiple sclerosis. J Mol Neurosci 4, 268-274.
    • (2011) J Mol Neurosci , vol.4 , pp. 268-274
    • Clarner, T.1    Buschmann, J.P.2    Beyer, C.3    Kipp, M.4
  • 64
    • 0026486606 scopus 로고
    • Ultrastructural localization of Alzheimer amyloid beta/A4 protein precursor in the cytoplasm of neurons and senile plaque-associated astrocytes
    • Yamaguchi H, Yamazaki T, Ishiguro K, Shoji M, Nakazato Y, Hirai S (1992) Ultrastructural localization of Alzheimer amyloid beta/A4 protein precursor in the cytoplasm of neurons and senile plaque-associated astrocytes. Acta Neuropathol 85, 15-22.
    • (1992) Acta Neuropathol , vol.85 , pp. 15-22
    • Yamaguchi, H.1    Yamazaki, T.2    Ishiguro, K.3    Shoji, M.4    Nakazato, Y.5    Hirai, S.6
  • 65
    • 67249087641 scopus 로고    scopus 로고
    • Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake
    • Li S, Hong S, Shepardson NE, Walsh DM, Shankar GM, Selkoe D (2009) Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake. Neuron 62, 788-801.
    • (2009) Neuron , vol.62 , pp. 788-801
    • Li, S.1    Hong, S.2    Shepardson, N.E.3    Walsh, D.M.4    Shankar, G.M.5    Selkoe, D.6
  • 66
    • 84877089562 scopus 로고    scopus 로고
    • Amyloid 1-42 slows clearance of synaptically released glutamate by mislocalizing astrocytic GLT-1
    • Scimemi A, Meabon JS, Woltjer RL, Sullivan JM, Diamond JS, Cook DG (2013) Amyloid 1-42 slows clearance of synaptically released glutamate by mislocalizing astrocytic GLT-1. J Neurosci 33, 5312-5318.
    • (2013) J Neurosci , vol.33 , pp. 5312-5318
    • Scimemi, A.1    Meabon, J.S.2    Woltjer, R.L.3    Sullivan, J.M.4    Diamond, J.S.5    Cook, D.G.6
  • 69
    • 0029794266 scopus 로고    scopus 로고
    • Expression and distribution of amyloid precursor protein-like protein-2 in Alzheimer's disease and in normal brain
    • Crain BJ, Hu W, Sze CI, Slunt HH, Koo EH, Price DL, Thinakaran G, Sisodia SS (1996) Expression and distribution of amyloid precursor protein-like protein-2 in Alzheimer's disease and in normal brain. Am J Pathol 149, 1087-1095.
    • (1996) Am J Pathol , vol.149 , pp. 1087-1095
    • Crain, B.J.1    Hu, W.2    Sze, C.I.3    Slunt, H.H.4    Koo, E.H.5    Price, D.L.6    Thinakaran, G.7    Sisodia, S.S.8
  • 70
    • 80053566644 scopus 로고    scopus 로고
    • FE65 proteins regulate NMDA receptor activation-induced amyloid precursor protein processing
    • Suh J, Lyckman A, Wang L, Eckman EA, Guénette SY (2011) FE65 proteins regulate NMDA receptor activation-induced amyloid precursor protein processing. J Neurochem 119, 377-388.
    • (2011) J Neurochem , vol.119 , pp. 377-388
    • Suh, J.1    Lyckman, A.2    Wang, L.3    Eckman, E.A.4    Guénette, S.Y.5
  • 71
    • 78650669822 scopus 로고    scopus 로고
    • The transcriptionally active amyloid precursor protein (APP) intracellular domain is preferentially produced from the 695 isoform of APP in a {beta}-secretase-dependent pathway
    • Belyaev ND, Kellett KA, Beckett C, Makova NZ, Revett TJ, Nalivaeva NN, Hooper NM, Turner AJ (2010) The transcriptionally active amyloid precursor protein (APP) intracellular domain is preferentially produced from the 695 isoform of APP in a {beta}-secretase-dependent pathway. J Biol Chem 285, 41443-41454.
    • (2010) J Biol Chem , vol.285 , pp. 41443-41454
    • Belyaev, N.D.1    Kellett, K.A.2    Beckett, C.3    Makova, N.Z.4    Revett, T.J.5    Nalivaeva, N.N.6    Hooper, N.M.7    Turner, A.J.8
  • 72
    • 80053918665 scopus 로고    scopus 로고
    • Soluble amyloid precursor protein: A novel proliferation factor of adult progenitor cells of ectodermal and mesodermal origin
    • Demars MP, Bartholomew A, Strakova Z, Lazarov O (2011) Soluble amyloid precursor protein: A novel proliferation factor of adult progenitor cells of ectodermal and mesodermal origin. Stem Cell Res Ther 2, 36-51. Nível Superior
    • (2011) Stem Cell Res Ther , vol.2 , pp. 36-51
    • Demars, M.P.1    Bartholomew, A.2    Strakova, Z.3    Lazarov, O.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.