Long dsRNA-mediated RNA interference and immunostimulation: A targeted delivery approach using polyethyleneimine based nano-carriers

Molecular Pharmaceutics

Volumn 11, Issue 3, 2014, Pages 872-884

  Sajeesh, S ^a   Lee, Tae Yeon ^a   Hong, Sun Woo ^a   Dua, Pooja ^a   Choe, Jeong Yong ^a   Kang, Aeyeon ^a   Yun, Wan Soo ^a   Song, Changsik ^a   Park, Sung Ha ^a   Kim, Soyoun ^b   Li, Chiang ^c   Lee, Dong Ki ^a  

^a Sungkyunkwan University   (South Korea)

^b Dongguk University   (South Korea)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

glioblastoma; immunostimulation; nanotechnology; RNA interference; siRNA delivery; targeted delivery

Indexed keywords

BETA INTERFERON; DOUBLE STRANDED RNA; HEPARIN; INTERLEUKIN 6; LONG DOUBLE STRANDED RNA; MESSENGER RNA; NANOCARRIER; PENTETIC ACID; POLYETHYLENEIMINE; POLYINOSINIC POLYCYTIDYLIC ACID; RNA INDUCED SILENCING COMPLEX; SMALL INTERFERING RNA; SURVIVIN; TRANSFERRIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; BIRC5 PROTEIN, HUMAN; DRUG CARRIER; INHIBITOR OF APOPTOSIS PROTEIN; POLYMER;

AGAR GEL ELECTROPHORESIS; ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; CANCER GENE THERAPY; CANCER INHIBITION; CELL DENSITY; CELL VIABILITY; CELL VIABILITY ASSAY; COMPLEX FORMATION; CONTROLLED STUDY; CROSS LINKING; CYTOTOXICITY; ENDOTHELIUM CELL; GENE SILENCING; GLIOBLASTOMA; HELA CELL; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; INTERNALIZATION; MOLECULARLY TARGETED THERAPY; MOUSE; NANOTECHNOLOGY; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RNA INTERFERENCE; STATIC ELECTRICITY; ZETA POTENTIAL; ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; ATOMIC FORCE MICROSCOPY; BRAIN; CELL CULTURE; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; GEL MOBILITY SHIFT ASSAY; GENE TRANSFER; GENETICS; METABOLISM; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BRAIN; CELL PROLIFERATION; CELLS, CULTURED; DRUG CARRIERS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENDOTHELIUM, VASCULAR; GENE TRANSFER TECHNIQUES; GLIOBLASTOMA; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; MICE; MICROSCOPY, ATOMIC FORCE; POLYETHYLENEIMINE; POLYMERS; RNA INTERFERENCE; RNA, DOUBLE-STRANDED; RNA, SMALL INTERFERING;

EID: 84901741881     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp400541z     Document Type: Article

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