Alkaline phosphatase ALPPL-2 is a novel pancreatic carcinoma-associated protein

Cancer Research

Volumn 73, Issue 6, 2013, Pages 1934-1945

  Dua, Pooja ^a,c   Kang, Hye Suk ^c   Hong, Seung Mo ^b   Tsao, Ming Sound ^d   Kim, Soyoun ^a   Lee, Dong Ki ^c  

^a Dongguk University   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

^c Sungkyunkwan University   (South Korea)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE PLACENTA ISOENZYME; ALKALINE PHOSPHATASE PLACENTA LIKE 2; APTAMER; MESSENGER RNA; TUMOR MARKER; UNCLASSIFIED DRUG;

ALPPL2 GENE; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INVASION; CELLULAR SECRETION; COMBINATORIAL CHEMISTRY; CONTROLLED STUDY; GENE; GENE EXPRESSION; GENE SILENCING; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MICROARRAY ANALYSIS; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; RNA INTERFERENCE;

ALKALINE PHOSPHATASE; BASE SEQUENCE; CELL DIVISION; CELL LINE, TUMOR; HUMANS; IMMUNOASSAY; MICROSCOPY, FLUORESCENCE; NEOPLASM INVASIVENESS; NUCLEIC ACID CONFORMATION; PANCREATIC NEOPLASMS; POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SELEX APTAMER TECHNIQUE; TUMOR MARKERS, BIOLOGICAL;

EID: 84875460621     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-3682     Document Type: Article

References (50)

1. Bardeesy N, DePinho RA. Pancreatic cancer biology and genetics. Nat Rev Cancer 2002;2:897-909.
2. Li D, Xie K, Wolff R, Abbruzzese JL. Pancreatic cancer. Lancet 2004;363:1049-57.
3. Brand R, Mahr C. Risk factors for pancreatic adenocarcinoma: are we ready for screening and surveillance? Curr Gastroenterol Rep 2005;7:122-7.
4. Lee MX, Saif MW. Screening for early pancreatic ductal adenocarcinoma: an urgent call! JOP 2009;10:104-8.
5. Gronborg M, Bunkenborg J, Kristiansen TZ, Jensen ON, Yeo CJ, Hruban RH, et al. Comprehensive proteomic analysis of human pancreatic juice. J Proteome Res 2004;3:1042-55.
6. Gronborg M, Kristiansen TZ, Iwahori A, Chang R, Reddy R, Sato N, et al. Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach. Mol Cell Proteomics 2006;5:157-71.
7. Weeks ME, Hariharan D, Petronijevic L, Radon TP, Whiteman HJ, Kocher HM, et al. Analysis of the urine proteome in patients with pancreatic ductal adenocarcinoma. Proteomics Clin Appl 2008;2: 1047-57.
8. Whiteaker JR, Lin C, Kennedy J, Hou L, Trute M, Sokal I, et al. A targeted proteomics-based pipeline for verification of biomarkers in plasma. Nat Biotechnol 2011;29:625-34.
9. le Coutre J, Whitelegge JP, Gross A, Turk E, Wright EM, Kaback HR, et al. Proteomics on full-length membrane proteins using mass spectrometry. Biochemistry 2000;39:4237-42.
10. Ellington AD, Szostak JW. In vitro selection of RNA molecules that bind specific ligands. Nature 1990;346:818-22.
11. Tuerk C, Gold L. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 1990;249:505-10.
12. Lee JF, Stovall GM, Ellington AD. Aptamer therapeutics advance. Curr Opin Chem Biol 2006;10:282-9.
13. Dua P, Kim S, Lee DK. Nucleic acid aptamers targeting cell-surface proteins. Methods 2011;54:215-25.
14. Shangguan D, Cao Z, Meng L, Mallikaratchy P, Sefah K, Wang H, et al. Cell-specific aptamer probes for membrane protein elucidation in cancer cells. J Proteome Res 2008;7:2133-9.
15. Ray P, Rialon-Guevara KL, Veras E, Sullenger BA, White RR. Comparing human pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate pancreatic cancer biomarker. J Clin Invest 2012;122:1734-41.
16. Daniels DA, Chen H, Hicke BJ, Swiderek KM, Gold L. A tenascin-C aptamer identified by tumor cell SELEX: systematic evolution of ligands by exponential enrichment. Proc Natl Acad Sci U S A 2003;100:15416-21.
17. Mallikaratchy P, Tang Z, Kwame S, Meng L, Shangguan D, Tan W. Aptamer directly evolved from live cells recognizes membrane bound immunoglobin heavy mu chain in Burkitt's lymphoma cells. Mol Cell Proteomics 2007;6:2230-8.
18. Ouyang H, Mou L, Luk C, Liu N, Karaskova J, Squire J, et al. Immortal human pancreatic duct epithelial cell lines with near normal genotype and phenotype. Am J Pathol 2000;157:1623-31.
19. Furukawa T, Duguid WP, Rosenberg L, Viallet J, Galloway DA, Tsao MS. Long-term culture and immortalization of epithelial cells from normal adult human pancreatic ducts transfected by the E6E7 gene of human papilloma virus 16. Am J Pathol 1996;148:1763-70.
20. Kang H.S, Min H.Y.M, Kim S, Lee DK. Isolation of RNA aptamers targeting HER-2-overexpressing breast cancer cells using cell-SELEX Bull. Korean Chem Soc 2009;30:1827.
21. Corpet F. Multiple sequence alignment with hierarchical clustering. Nucleic Acids Res 1988;16:10881-90.
22. Matzura O, Wennborg A. RNAdraw: an integrated program for RNA secondary structure calculation and analysis under 32-bit Microsoft Windows. Comput Appl Biosci 1996;12:247-9.
23. Dua P, Yoo JW, Kim S, Lee DK. Modified siRNA structure with a single nucleotide bulge overcomes conventional siRNA-mediated off-target silencing. Mol Ther 2011;19:1676-87.
24. Irizarry RA, Bolstad BM, Collin F, Cope LM, Hobbs B, Speed TP. Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res 2003;31:e15.
25. Dennis G Jr, Sherman BT, Hosack DA, Yang J, Gao W, Lane HC, et al. DAVID: database for annotation visualization, and integrated discovery. Genome Biol 2003;4:P3.
26. Bartlett DW, Davis ME. Effect of siRNA nuclease stability on the in vitro and in vivo kinetics of siRNA-mediated gene silencing. Biotechnol Bioeng 2007;97:909-21.
27. Le Du MH, Stigbrand T, Taussig MJ, Menez A, Stura EA. Crystal structure of alkaline phosphatase from human placenta at 1.8 A resolution. Implication for a substrate specificity. J Biol Chem 2001;276:9158-65.
28. Koyama I, Hirano K, Makiya R, Stendahl U, Stigbrand T. Purification and characterisation of the placental-like alkaline phosphatase from ovarian epithelial tumours. Br J Cancer Suppl 1990;10:6-11.
29. Watanabe T, Wada N, Chou JY. Structural and functional analysis of human germ cell alkaline phosphatase by site-specific mutagenesis. Biochemistry 1992;31:3051-8.
30. Otto VI, Fried R, Wiederkehr F, Hanseler E. Separation of the two most closely related isoenzymes of alkaline phosphatase by two-dimensional electrophoresis. Electrophoresis 1995;16:1284-8.
31. Roelofs H, Manes T, Janszen T, Millan JL, Oosterhuis JW, Looijenga LH. Heterogeneity in alkaline phosphatase isozyme expression in human testicular germ cell tumours: An enzyme-/immunohistochemical and molecular analysis. J Pathol 1999;189:236-44.
32. Hoylaerts MF, Millan JL. Site-directed mutagenesis and epitopemapped monoclonal antibodies define a catalytically important conformational difference between human placental and germ cell alkaline phosphatase. Eur J Biochem 1991;202:605-16.
33. Neumann A, Keller T, Jocham D, Doehn C. [Human placental alkaline phosphatase (hPLAP) is the most frequently elevated serum marker in testicular cancer]. Aktuelle Urol 2011;42:311-5.
34. Wolf JS, Chen Z, Dong G, Sunwoo JB, Bancroft CC, Capo DE, et al. IL (interleukin)-1alpha promotes nuclear factor-kappaB and AP-1- induced IL-8 expression, cell survival, and proliferation in head and neck squamous cell carcinomas. Clin Cancer Res 2001;7:1812-20.
35. Lesina M, Kurkowski MU, Ludes K, Rose-John S, Treiber M, Kloppel G, et al. Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer. Cancer Cell 2011;19:456-69.
36. Haan C, Kreis S, Margue C, Behrmann I. Jaks and cytokine receptors- an intimate relationship. Biochem Pharmacol 2006;72:1538-46.
37. Schuler S, Diersch S, Hamacher R, Schmid RM, Saur D, Schneider G. SKP2 confers resistance of pancreatic cancer cells towards TRAILinduced apoptosis. Int J Oncol 2011;38:219-25
38. Takano Y, Kato Y, Masuda M, Ohshima Y, Okayasu I. Cyclin D2, but not cyclin D1, overexpression closely correlates with gastric cancer progression and prognosis. J Pathol 1999;189:194-200.
39. Masood A, Azmi AS,MohammadRM.Small molecule inhibitors of Bcl-2 family proteins for pancreatic cancer therapy. Cancers 2011;3:1527-49.
40. Ochi Y, Okabe H, Inui T, Yamashiro K. [Tumor marker-present and future]. Rinsho Byori 1997;45:875-83.
41. Ial'chenko NA, Lagutin VD, Lavik NN, Musin II. The clinical information value of an immunoenzyme study of the tumor markers CA-19-9, CEA and AFP in cancer of the stomach, pancreas, colon and rectum. Vopr Onkol 1991;37:921-4.
42. Jeppsson A, Wahren B, Brehmer-Andersson E, Silfversward C, Stigbrand T, Millan JL. Eutopic expression of placental-like alkaline phosphatase in testicular tumors. Int J Cancer 1984;34:757-61.
43. Paiva J, Damjanov I, Lange PH, Harris H. Immunohistochemical localization of placental-like alkaline phosphatase in testis and germ-cell tumors using monoclonal antibodies.AmJ Pathol 1983;111: 156-65.
44. Stendahl U, Lindgren A, Tholander B, Makyia R, Stigbrand T. Expression of placental alkaline phosphatase in epithelial ovarian tumours. Tumour Biol 1989;10:126-32.
45. Millan JL, Fishman WH. Biology of human alkaline phosphatases with special reference to cancer. Crit Rev Clin Lab Sci 1995;32:1-39.
46. Hustinx SR, Cao D, Maitra A, Sato N, Martin ST, Sudhir D, et al. Differentially expressed genes in pancreatic ductal adenocarcinomas identified through serial analysis of gene expression. Cancer Biol Ther 2004;3:1254-61.
47. Nathanson L, Fishman WH. New observations on the Regan isoenzyme of alkaline phosphatase in cancer patients. Cancer 1971;27: 1388-97.
48. Bellazi L, Mornet E, Meurice G, Pata-Merci N, De Mazancourt P, Dieudonne MN. Genome wide expression profile in human HTR-8/ Svneo trophoblastic cells in response to overexpression of placental alkaline phosphatase gene. Placenta 2011;32:771-7.
49. Deer EL, González-Hernández J, Coursen JD, Shea JE, Ngatia J, Scaife CL, et al. Phenotype and genotype of pancreatic cancer cell lines. Pancreas 2010;39:425-35.
50. O'Connor MD, Kardel MD, Iosfina I, Youssef D, Lu M, Li MM, et al. Alkaline phosphatase-positive colony formation is a sensitive, specific, and quantitative indicator of undifferentiated human embryonic stem cells. Stem Cells 2008;26:1109-16.