CYP2J2 and EETs protect against oxidative stress and apoptosis in vivo and in vitro following lung ischemia/reperfusion

Cellular Physiology and Biochemistry

Volumn 33, Issue 6, 2014, Pages 1663-1680

  Chen, Wenshu ^a,b   Zheng, Guanying ^b   Yang, Shijiang ^c   Ping, Wei ^a   Fu, Xiangning ^a   Zhang, Ni ^a   Wang, Dao Wen ^a   Wang, Jianing ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b FUJIAN MEDICAL UNIVERSITY   (China)

^c CENTRAL HOSPITAL OF WUHAN   (China)

Author keywords

Apoptosis; Cytochrome P450 epoxygenase 2J2; Epoxyeicosatrienoic acids; Lung ischemia reperfusion injury; Oxidative stress

Indexed keywords

14,15 EPOXY 5,8,11 ICOSATRIENOIC ACID; 2 MORPHOLINO 8 PHENYLCHROMONE; CASPASE 3; CYTOCHROME P450 2J2; EPOXYICOSATRIENOIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; 14,15-DIHYDROXYEICOSATRIENOIC ACID; ARACHIDONATE EPOXYGENASE; CYTOCHROME P450; DIHOMO GAMMA LINOLENIC ACID; OXYGEN; PROTECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANOXIA; APOPTOSIS; ARTICLE; CELL VIABILITY; COLLAPSE; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG INJURY; LUNG PARENCHYMA; MALE; MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PULMONARY ARTERY; RAT; REOXYGENATION; REPERFUSION INJURY; ANALOGS AND DERIVATIVES; ANIMAL; CELL CULTURE; CELL HYPOXIA; CELL SURVIVAL; DRUG EFFECTS; FLOW CYTOMETRY; GENETICS; LUNG; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; PATHOPHYSIOLOGY; VASCULARIZATION; WESTERN BLOTTING; WISTAR RAT; ANIMAL CELL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; GENETIC TRANSFECTION; ISCHEMIA; LUNG HILUS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

RATTUS;

8,11,14-EICOSATRIENOIC ACID; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL HYPOXIA; CELL SURVIVAL; CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; ENDOTHELIAL CELLS; FLOW CYTOMETRY; HUMANS; LUNG; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; OXIDATIVE STRESS; OXYGEN; PROTECTIVE AGENTS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY;

EID: 84901736993     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000362950     Document Type: Article

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