CYP2J2 overexpression increases EETs and protects against angiotensin II-induced abdominal aortic aneurysm in mice

Journal of Lipid Research

Volumn 54, Issue 5, 2013, Pages 1448-1456

  Cai, Zhejun ^a,b   Zhao, Gang ^a   Yan, Jiangtao ^a   Liu, Wanjun ^a   Feng, Wenjing ^a   Ma, Ben ^a   Yang, Lei ^a   Wang, Jian An ^b   Tu, Ling ^a   Wang, Dao Wen ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Abdominal aortic aneurysm; Angiotensin II; Cytochrome P450 epoxygenase 2J2; Epoxyeicosatrienoic acid; Inflammation

Indexed keywords

11,12 EPOXY 5,8,14 ICOSATRIENOIC ACID; ADENOVIRUS VECTOR; ARACHIDONIC ACID; CHOLESTEROL; CYTOCHROME P450 2J2; ELASTIN; EPOXYICOSATRIENOIC ACID; GELATINASE A; GELATINASE B; HIGH DENSITY LIPOPROTEIN; I KAPPA B ALPHA; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN; MATRIX METALLOPROTEINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTION FACTOR RELA; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ABDOMINAL AORTA ANEURYSM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FATTY ACID BLOOD LEVEL; FATTY ACID SYNTHESIS; MACROPHAGE MIGRATION; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; UPREGULATION; URINE LEVEL; VASCULAR SMOOTH MUSCLE; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING;

ANGIOTENSIN II; ANIMALS; AORTIC ANEURYSM, ABDOMINAL; ARACHIDONIC ACIDS; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION REGULATION; HUMANS; MACROPHAGES; MICE; MUSCLE, SMOOTH, VASCULAR; PPAR GAMMA;

EID: 84876808579     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M036533     Document Type: Article

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