Decreased SIRT2 activity leads to altered microtubule dynamics in oxidatively-stressed neuronal cells: Implications for Parkinson's disease

Experimental Neurology

Volumn 257, Issue , 2014, Pages 170-181

  Patel, Vivek P ^a,b   Chu, Charleen T ^a,b,c  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c MCGOWAN INSTITUTE FOR REGENERATIVE MEDICINE   (United States)

Author keywords

Microtubule dynamics; Oxidative stress; Parkinson's disease; Sirtuin

Indexed keywords

HISTONE DEACETYLASE 6; LACTATE DEHYDROGENASE; OXIDOPAMINE; SIRTUIN 2; TUBULIN;

ACETYLATION; ARTICLE; CELL AGING; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME RELEASE; GROWTH RATE; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; LACTATE DEHYDROGENASE BLOOD LEVEL; MICROTUBULE; MOLECULAR IMAGING; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; OXIDATIVE STRESS; PARKINSON DISEASE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION;

MICROTUBULE DYNAMICS; OXIDATIVE STRESS; PARKINSON'S DISEASE; SIRTUIN;

CELL LINE, TUMOR; CELL PROLIFERATION; COMPLEMENT C1; HISTONE DEACETYLASES; HUMANS; L-LACTATE DEHYDROGENASE; LUMINESCENT PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; NEURITES; NEUROBLASTOMA; NEURONS; NEUROTOXINS; OXIDATIVE STRESS; OXIDOPAMINE; REACTIVE OXYGEN SPECIES; SIRTUIN 2; TIME FACTORS; TRETINOIN;

EID: 84901656353     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2014.04.024     Document Type: Article

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