Comparison between proliferative and neuron-like SH-SY5Y cells as an in vitro model for Parkinson disease studies

Brain Research

Volumn 1337, Issue , 2010, Pages 85-94

  Lopes, Fernanda Martins ^a,b   Schröder, Rafael ^a   Júnior, Mário Luiz Conte da Frota ^a   Zanotto Filho, Alfeu ^a   Müller, Carolina Beatriz ^a,b   Pires, André Simões ^a   Meurer, Rosalva Thereza ^c   Colpo, Gabriela Delevati ^b,d   Gelain, Daniel Pens ^a   Kapczinski, Flávio ^b,d   Moreira, José Cláudio Fonseca ^a   Fernandes, Marilda da Cruz ^c   Klamt, Fabio ^a,b  

^a Instituto de Ciencias Biologicas e da Saude Pontifical Catholic University of Minas Gerais   (Brazil)

^b National Institute for Translational Medicine INCT TM   (Brazil)

^c UNIVERSIDADE FEDERAL DE CIÊNCIAS DA SAÚDE DE PORTO ALEGRE   (Brazil)

^d HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

Author keywords

6 hydroxydopamine; DJ 1; Parkinson Disease

Indexed keywords

DJ 1 PROTEIN; OXIDOPAMINE; RETINOIC ACID;

ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRAIN; CELL STRUCTURE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOTOXICITY; DOPAMINERGIC NERVE CELL; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; NEUROPROTECTION; PARKINSON DISEASE; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

ADRENERGIC AGENTS; ANIMALS; BIOLOGICAL MARKERS; CATTLE; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KERATOLYTIC AGENTS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NEUROBLASTOMA; ONCOGENE PROTEINS; OXIDOPAMINE; PARKINSON DISEASE; TRETINOIN;

BOVINAE;

EID: 77952544603     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.03.102     Document Type: Article

References (54)

1. Bastien J., and Rochette-Egly C. Nuclear retinoid receptors and the transcription of retinoid-target genes. Gene 328 (2004) 1-16
2. Biedler J.L., Roffler-Tarlov S., Schachner M., and Freedman L.S. Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones. Cancer Res. 38 (1978) 3751-3757
3. Bladini F., Armentero M.T., and Martignoni E. The 6-hydroxydopamine model: news form the past. Parkinsonism. Relat Disord. 14 (2008) 124-129
4. Bonifati V., Rizzu P., Squitieri F., Krieger E., Vanacore N., van Swieten J.C., Brice A., van Duijn C.M., Oostra B., Meco G., and Heutink P. Mutations in the DJ-1 gene associated with autosomal recessive early-onset Parkinsonism. Science 299 (2003) 256-259
5. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
6. Chen L., Malcolm A.J., Wood K.M., Cole M., Variendm S., Cullinane C., Pearson A.D.J., Lunec J., and Tweddle D.A. p53 is nuclear and functional in both undifferentiated and differentiated neuroblastoma. Cell cycle 6 (2007) 2685-2696
7. Cheung Y.T., Lau W.K., Yu M.S., Lai C.S., Yeung S.C., So K.F., and Chang R.C. Effect of all-trans-retinoic acid on human SH-SY5Y neuroblastoma as in vitro model in neurotoxicity research. Neurotoxicology 30 (2009) 127-135
8. Chin M.H., Qian W.J., Wang H., Petryuk V.A., Bloom J.S., Sforza D.M., Lacán G., Liu D., Khan A.H., Cantor R.M., Bigelow D.J., Melega W.P., Camp II D.G., Smith R.D., and Smith D.J. Mitochondrial dysfunction, oxidative stress, and apoptosis revealed by proteomic and transcriptomic analyses of the striata in two mouse models of Parkinson's disease. J. Proteome Res. 7 (2008) 666-677
9. Clements C.M., McNally R.S., Conti B.J., Mak T.W., and Ting J.P. DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2. Proc. Natl Acad. Sci. USA 103 (2006) 15091-15096
10. Dawson T.M., and Dawson V.L. Molecular pathways of neurodegeneration in Parkinson's disease. Science 302 (2003) 819-821
11. Dunkley P.R., Bobrovskaya L., Graham M.E., von Nagy-Felsobuki E.I., and Dickson P.W. Tyrosine hydroxylase phosphorylation: regulation and consequences. J. Neurochem. 91 (2004) 1025-1043
12. Fang F., Wang A.P., and Yang S.F. Antitumor activity of a novel recombinant mutant human tumor necrosis factor-related apoptosis-inducing ligand. Acta pharmacol. Sin. 26 (2005) 1373-1381
13. Fuchs E., and Weber K. Intermediate filaments: structure, dynamics, function, and disease. Annu. Rev. Biochem. 63 (1994) 345-382
14. Gilany K., Elzen R.V., Mous K., Coen E., Dongen W.V., Vandamme S., Gevaert K., Timmerman E., Vandekerckhove J., Dewilde S., Ostade X.V., and Moens L. The proteome of the human neuroblastoma cell line SH-SY5Y: an enlarged proteome. Biochim. Biophys. Acta 1784 (2008) 983-985
15. Gomez-Lazaro M., Bonekamp N.A., Galindo M.F., Jordan J., and Schrader M. 6-Hydroxydopamine (6-OHDA) induces Drp1-dependent mitochondrial fragmentation in SH-SY5Y cells. Free Radic. Biol. Med. 11 (2008) 1690-1699
16. Guarnieri S., Pilla R., Morabito C., Sacchetti S., Mancinelli R., Fano G., and Mariggiò M.A. Extracellular guanosine and GTP promote expression of differentiation markers and induce S-phase cell-cycle arrest in human SH-SY5Y neuroblastoma cells. Int. J. Dev. Neurosci. 27 (2009) 135-147
17. Hockfield S., and McKay R.D. Identification of major cell classes in the developing mammalian nervous system. J. Neurosci. 5 (1985) 3310-3328
18. Hwang Y.P., and Jeong H.G. The coffee diterpene kahweol induces heme oxygenase-1 via the PI3K and p38/Nrf2 pathway to protect human dopaminergic neurons from 6-hydroxydopamine-derived oxidative stress. FEBS Lett. 17 (2008) 2655-2662
19. Inden M., Taira T., Kitamura Y., Yanagida T., Tsuchiya D., Takata K., Yanagisawa D., Nishimura K., Taniguchi T., Kiso Y., Yoshimoto K., Agatsuma T., Koide-Yoshida S., Iguchi-Ariga S.M., Shimohama S., and Ariga H. PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson's disease rat model. Neurobiol. Dis. 24 (2006) 144-158
20. Ikeda Y., Tsuji S., Satoh A., Ishikura M., Shirasawa T., and Shimizu T. Protective effects of astaxanthin on 6-hydroxydopamine-induced apoptosis in human neuroblastoma SH-SY5Y cells. J. Neurochem. 107 (2008) 1730-1740
21. Klamt F., and Schacter E. Taurine chloramine, an oxidant derived from neutrophilis, induces apoptosis in human B lymphoma cells through mitochondrial damage. J. Biol. Chem. 280 (2005) 21346-21352
22. Jordan J., Galindo M.F., Tornero D., Gonzalez-Garcia C., and Cena V. Bcl-xL blocks mitochondrial multiple conductance channel activation and inhibits 6-OHDA-induced death in SH-SY5Y cells. J. Neurochem. 89 (2004) 124-133
23. Lee C.S., Han J.H., Jang Y.Y., Song J.H., and Han E.S. Differential effect of catecholamines and MPP on membrane permeability in brain mitochondria and cell viability in PC12 cells. Neurochem. Int. 40 (2002) 361-369
24. Lehmensiek V., Tan E.M., Liebau S., Lenk T., Zettlmeisl H., Schwarz J., and Storch A. Dopamine transporter-mediated cytotoxicity of 6-hydroxydopamine in vitro depends on expression of mutant a-synucleins related to Parkinson's disease. Neurochem. Int. 48 (2006) 329-340
25. Lesage S., and Brice A. Parkinson's disease: from monogenic forms to genetic susceptibility factors. Hum. Mol. Genet. 18 (2009) 48-50
26. Lev N., Ickowicz D., Melamed E., and Offen D. Oxidative insults induce DJ-1 upregulation and redistribution: implications for neuroprotection. Neurotoxicology 29 (2008) 397-405
27. Liu, F., Nguyen, J.L., Hulleman, J.D., Li, L., Rochet, J.C., 2008. Mechanisms of DJ-1 neuroprotection in a cellular model of Parkinson's disease. J Neurochem.
28. Lo Bianco C., Schneider B.L., Bauer M., Sajadi A., Brice A., Iwatsubo T., and Aebischer P. Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an a-synuclein rat model of Parkinson's disease. Proc. Natl Acad. Sci. USA 101 (2004) 17510-17515
29. López-Carballo G., Moreno L., Masiá S., Pérez P., and Barettino D. Activation of the phosphatidylinositol 3-kinase/Akt signaling pathway by retinoic acid is required for neural differentiation of SH-SY5Y human neuroblastoma cells. J. Biol. Chem. 28 (2002) 25297-25304
30. Mark M., Ghyselinck N.B., and Chambon P. Function of retinoid nuclear receptors: lessons from genetic and pharmacological dissections of the retinoic acid signaling pathway during mouse embryogenesis. Annu. Rev. Pharmacol. Toxicol. 46 (2006) 451-480
31. Miloso M., Villa D., Crimi M., Galbiati S., Donzelli E., Nicolini G., and Tredici G. Retinoic acid-induced neuritogenesis of human neuroblastoma SH-SY5Y cells is ERK independent and PKC dependent. J. Neurosci. Res. 75 (2004) 241-252
32. Miyazaki, S., Yanagida, T., Nunome, K., Ishikawa, S., Inden, M., Kitamura, Y., Nakagawa, S., Taira, T., Hirota, K., Niwa, M., Iguchi-Ariga, S.M., Ariga, H., 2008. DJ-1-Binding Compounds Prevent Oxidative Stress-Induced Cell Death and Movement Defect in Parkinson's Disease Model Rats. J Neurochem.
33. Mizote T., Tsuda M., Smith D.D.S., Nakayama H., and Nakazawa T. Cloning and characterization of the thiD/J gene of Escherichia coli encoding a thiamin-synthesizing bifunctional enzyme, hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase. Microbiology 145 (1999) 495-501
34. Moll U.M., LaQuaglia M., Benard J., and Riou G. Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors. Proc. Natl Acad. Sci. USA 92 (1995) 4407-4411
35. Mu X., He G., Cheng Y., Li X., Xu B., and Du G. Baicalein enxerts neuroprotective effects in 6-hydroxydopamine-induced experimental parkinsonism in vivo and in vitro. Pharmacol. Biochem. Behav. 92 (2009) 642-648
36. Nie G., Cao Y., and Zhao B. Protective effects of green tea polyphenols and their major component, (-)-epigallocatechin-3-gallate (EGCG), on 6-hydroxydopamine-induced apoptosis in PC12 cells. Redox Rep. 7 (2002) 171-177
37. Odelstad L., Pahlman S., Nilsson K., Larsson E., Lackgren G., Johansson K.E., Hjerten S., and Grotte G. Neuron specific enolase in relation to differentiation in human neuroblastoma. Brain Res. 224 (1981) 69-82
38. Pahlman S., Ruusala A.I., Abrahamsson L., Mattsson M.E., and Esscher T. Retinoic acid-induced differentiation of cultured human neuroblastoma cells: a comparison with phorbolester-induced differentiation. Cell Differ. 14 (1984) 135-144
39. Prabhakara J.P.R., Feist G., Thomasson S., Thompson A., Schommer E., and Ghribi O. Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and α-synuclein in human neuroblastoma SH-SY5Y cells. J. Neurochem. 107 (2008) 1722-1729
40. Poewe W. Non-motor symptoms in Parkinson's disease. Eur. J. Neurol. 15 (2008) 14-20
41. Reimer R., Helmbold H., Szalay B., Hagel C., Hohenberg H., Deppert W., and Bohn W. Nestin modulates glucocorticoid receptor function by cytoplasmic anchoring. Plos One 29 (2009) e6084
42. Sahlgren C.M., Pallari H.M., He T., Chou Y.H., Goldman R.D., and Eriksson J.E. A nestin scaffold links Cdk5/p35 signaling to oxidant-induced cell death. Embo J. 25 (2006) 4808-4819
43. Sarkanen J.R., Nykky J., Siikanen J., Selinummi J., Ylokomi T., and Janolen T.O. Cholesterol supports the retinoic acid-induced synaptic vesicle formation in differentiating human SH-SY5Y neuroblastoma cells. J. Neurochem. 102 (2007) 1941-1952
44. Savickiene J., Treigyte G., Magnusson K.E., and Navakauskiene R. Response of retinoic acid-resistant KG1 cells to combination of retinoic acid with diverse histone deacetylase inhibitors. Ann. N. Y. Acad. Sci. 1171 (2009) 321-333
45. Schapira A.H. Mitochondrial dysfunction in neurodegenerative disease. Neurochem. Res. 12 (2008) 2502-2509
46. Seitz G., Stegmann H.B., Jager H.H., Schlude H.M., Wolburg H., Roginsky V.A., Niethammer D., and Bruchelt G. Neuroblastoma cells expressing the noradrenaline transporter are destroyed more selectively by 6-fluorodopamine than by 6-hydroxydopamine. J. Neurochem. 75 (2000) 511-520
47. 2-induced cell death. Free Radic. Res. 40 (2006) 155-165
48. Thomas S.K., Messam C.A., Spengler B.A., and Biedler J.L. Nestin is a potential mediator of malignancy in human neuroblastoma cells. J. Biol. Chem. 279 (2004) 27994-27999
49. Tieu K., Zuo D.M., and Yu P.H. Differential effects of staurosporine and retinoic acid on the vulnerability of the SH-SY5Y neuroblastoma cells: involvement of Bcl-2 and p53 proteins. J. Neurosci. Res. 58 (1999) 426-435
50. Weggen S., Bayer T.A., Koch A., Salewski H., Scheidtmann K.H., Pietsch T., and Wiestler O.D. Characterization of neural cell lines derived from SV40 large T-induced primitive neuroectodermal tumors. Brain Pathol. 7 (1997) 731-739
51. Weyer A., and Schilling K. Developmental and cell type-specific expression of the neuronal marker NeuN in the murine cerebellum. J. Neurosci. Res. 73 (2003) 400-409
52. Xu J., Zhong N., Wang H., Elias J.E., Kim C.Y., Woldman I., Pifl C., Gygi S.P., Geula C., and Yankner B.A. The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis. Hum. Mol. Genet. 14 (2005) 231-1241
53. Zhang L., Shimoji M., Thomas B., Moore D.J., Yu S.H., Marupudi N.I., Torp R., Torgner I.A., Ottersen O.P., Dawson T.M., and Dawson V.L. Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis. Hum. Mol. Genet. 14 (2005) 203-2073
54. Zhong N., and Xu J. Synergistic activation of the human MnSOD promoter by DJ-1 and PGC-1alpha: regulation by SUMOylation and oxidation. Hum. Mol. Genet. 17 (2008) 3357-3367