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Volumn 193, Issue 2, 2010, Pages 189-202

Transcriptome profiling in neurodegenerative disease

Author keywords

Alzheimer's disease; DNA microarrays; Huntington's disease; Next generation DNA sequencing; Parkinson's disease; RNA Seq; Transcriptome

Indexed keywords

TRANSCRIPTOME;

EID: 78049385467     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2010.08.018     Document Type: Review
Times cited : (50)

References (160)
  • 1
    • 0023622899 scopus 로고
    • Neostriatal dopamine uptake and reversal of age-related movement disorders with dopamine-uptake inhibitors
    • Altar C.A., Marshall J.F. Neostriatal dopamine uptake and reversal of age-related movement disorders with dopamine-uptake inhibitors. Ann N Y Acad Sci 1988, 515:343-354.
    • (1988) Ann N Y Acad Sci , vol.515 , pp. 343-354
    • Altar, C.A.1    Marshall, J.F.2
  • 2
    • 22444441576 scopus 로고    scopus 로고
    • Deficient hippocampal neuron expression of proteasome, ubiquitin, and mitochondrial genes in multiple schizophrenia cohorts
    • Altar C.A., Jurata L.W., Charles V., Lemire A., Liu P., Bukhman Y., et al. Deficient hippocampal neuron expression of proteasome, ubiquitin, and mitochondrial genes in multiple schizophrenia cohorts. Biol Psychiatry 2005, 58:85-96.
    • (2005) Biol Psychiatry , vol.58 , pp. 85-96
    • Altar, C.A.1    Jurata, L.W.2    Charles, V.3    Lemire, A.4    Liu, P.5    Bukhman, Y.6
  • 3
    • 57649129041 scopus 로고    scopus 로고
    • Target identification for CNS diseases by transcriptional profiling
    • Altar C.A., Vawter M.P., Ginsberg S.D. Target identification for CNS diseases by transcriptional profiling. Neuropsychopharmacology 2009, 34(1):18-54.
    • (2009) Neuropsychopharmacology , vol.34 , Issue.1 , pp. 18-54
    • Altar, C.A.1    Vawter, M.P.2    Ginsberg, S.D.3
  • 4
    • 0142040220 scopus 로고    scopus 로고
    • Effects of electroconvulsive seizures and antidepressent drugs on brain-derived neurotrophic factor protein in rat brain
    • Altar C.A., Whitehead R.E., Chen R., Wortwein G., Masden T.M. Effects of electroconvulsive seizures and antidepressent drugs on brain-derived neurotrophic factor protein in rat brain. Biol Psychiatry 2003, 54:703-709.
    • (2003) Biol Psychiatry , vol.54 , pp. 703-709
    • Altar, C.A.1    Whitehead, R.E.2    Chen, R.3    Wortwein, G.4    Masden, T.M.5
  • 5
    • 20044367108 scopus 로고    scopus 로고
    • Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms
    • Andorfer C., Acker C.M., Kress Y., Hof P.R., Duff K., Davies P. Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms. J Neurosci 2005, 25:5446-5545.
    • (2005) J Neurosci , vol.25 , pp. 5446-5545
    • Andorfer, C.1    Acker, C.M.2    Kress, Y.3    Hof, P.R.4    Duff, K.5    Davies, P.6
  • 6
    • 0023943181 scopus 로고
    • Differential alteration of various cholinergic markers in cortical and subcortical regions of human brain in Alzheimer's disease
    • Araujo D.M., Lapchak P.A., Robitaille Y., Gauthier S., Quirion R. Differential alteration of various cholinergic markers in cortical and subcortical regions of human brain in Alzheimer's disease. J Neurochem 1988, 50:1914-1923.
    • (1988) J Neurochem , vol.50 , pp. 1914-1923
    • Araujo, D.M.1    Lapchak, P.A.2    Robitaille, Y.3    Gauthier, S.4    Quirion, R.5
  • 7
    • 39249083317 scopus 로고    scopus 로고
    • Loss of phospholipid asymmetry and elevated brain apoptotic protein levels in subjects with amnestic mild cognitive impairment and Alzheimer disease
    • Bader Lange M.L., Cenini G., Piroddi M., Abdul H.M., Sultana R., Galli F., et al. Loss of phospholipid asymmetry and elevated brain apoptotic protein levels in subjects with amnestic mild cognitive impairment and Alzheimer disease. Neurobiol Dis 2008, 29:456-464.
    • (2008) Neurobiol Dis , vol.29 , pp. 456-464
    • Bader Lange, M.L.1    Cenini, G.2    Piroddi, M.3    Abdul, H.M.4    Sultana, R.5    Galli, F.6
  • 9
    • 0038206578 scopus 로고    scopus 로고
    • Gene microarrays in hippocampal aging: statistical profiling identifies novel processes correlated with cognitive impairment
    • Blalock E.M., Chen K.C., Sharrow K., Herman J.P., Porter N.M., Foster T.C., et al. Gene microarrays in hippocampal aging: statistical profiling identifies novel processes correlated with cognitive impairment. J Neurosci 2003, 23:3807-3819.
    • (2003) J Neurosci , vol.23 , pp. 3807-3819
    • Blalock, E.M.1    Chen, K.C.2    Sharrow, K.3    Herman, J.P.4    Porter, N.M.5    Foster, T.C.6
  • 10
    • 0031148892 scopus 로고    scopus 로고
    • Decreased TrkA gene expression in cholinergic neurons of the striatum and basal forebrain of patients with Alzheimer's disease
    • Boissiere F., Faucheux B., Ruberg M., Agid Y., Hirsch E.C. Decreased TrkA gene expression in cholinergic neurons of the striatum and basal forebrain of patients with Alzheimer's disease. Exp Neurol 1997, 145:245-252.
    • (1997) Exp Neurol , vol.145 , pp. 245-252
    • Boissiere, F.1    Faucheux, B.2    Ruberg, M.3    Agid, Y.4    Hirsch, E.C.5
  • 11
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H., Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 1991, 82:239-259.
    • (1991) Acta Neuropathol , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 12
    • 0036668567 scopus 로고    scopus 로고
    • Quantification of mRNA using real-time reverse transcription PCR (RT-PCR): trends and problems
    • Bustin S.A. Quantification of mRNA using real-time reverse transcription PCR (RT-PCR): trends and problems. J Mol Endocrinol 2002, 29:23-39.
    • (2002) J Mol Endocrinol , vol.29 , pp. 23-39
    • Bustin, S.A.1
  • 13
    • 0028989895 scopus 로고
    • Neurons bearing neurofibrillary tangles are responsible for selected synaptic deficitys in Alzheimer's disease
    • Callahan L.M., Coleman P.D. Neurons bearing neurofibrillary tangles are responsible for selected synaptic deficitys in Alzheimer's disease. Neurobiol Aging 1995, 16:311-314.
    • (1995) Neurobiol Aging , vol.16 , pp. 311-314
    • Callahan, L.M.1    Coleman, P.D.2
  • 14
    • 0033025080 scopus 로고    scopus 로고
    • Quantitative decrease in synaptophysin message expression and increase in cathepsin D message expression in Alzheimer disease neurons containing neurofibrillary tangles
    • Callahan L.M., Vaules W.A., Coleman P.D. Quantitative decrease in synaptophysin message expression and increase in cathepsin D message expression in Alzheimer disease neurons containing neurofibrillary tangles. J Neuropathol Exp Neurol 1999, 58:275-287.
    • (1999) J Neuropathol Exp Neurol , vol.58 , pp. 275-287
    • Callahan, L.M.1    Vaules, W.A.2    Coleman, P.D.3
  • 15
    • 2342494269 scopus 로고    scopus 로고
    • Differential preservation of AMPA receptor subunits in the hippocampi of Alzheimer's disease patients according to Braak stage
    • Carter T.L., Rissman R.A., Mishizen-Eberz A.J., Wolfe B.B., Hamilton R.L., Gandy S., et al. Differential preservation of AMPA receptor subunits in the hippocampi of Alzheimer's disease patients according to Braak stage. Exp Neurol 2004, 187:299-309.
    • (2004) Exp Neurol , vol.187 , pp. 299-309
    • Carter, T.L.1    Rissman, R.A.2    Mishizen-Eberz, A.J.3    Wolfe, B.B.4    Hamilton, R.L.5    Gandy, S.6
  • 16
    • 0030659826 scopus 로고    scopus 로고
    • Isolation of single immunohistochemically identified whole neuronal cell bodies from post-mortem human brain for simultaneous analysis of multiple gene expression
    • Cheetham J.E., Coleman P.D., Chow N. Isolation of single immunohistochemically identified whole neuronal cell bodies from post-mortem human brain for simultaneous analysis of multiple gene expression. J Neurosci Methods 1997, 77:43-48.
    • (1997) J Neurosci Methods , vol.77 , pp. 43-48
    • Cheetham, J.E.1    Coleman, P.D.2    Chow, N.3
  • 17
    • 57649137070 scopus 로고    scopus 로고
    • Mitochondrial dysfunction, oxidative stress, and apoptosis revealed by proteomic and transcriptomic analyses of the striata in two mouse models of Parkinson's disease
    • Chin M.H., Qian W.J., Wang H., Petyuk V.A., Bloom J.S., Sforza D.M., et al. Mitochondrial dysfunction, oxidative stress, and apoptosis revealed by proteomic and transcriptomic analyses of the striata in two mouse models of Parkinson's disease. J Proteome Res 2008, 4:4.
    • (2008) J Proteome Res , vol.4 , pp. 4
    • Chin, M.H.1    Qian, W.J.2    Wang, H.3    Petyuk, V.A.4    Bloom, J.S.5    Sforza, D.M.6
  • 18
    • 1842581669 scopus 로고    scopus 로고
    • Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated idiopathic Parkinson's and Alzheimer's diseases
    • Choi J., Levey A.I., Weintraub S.T., Rees H.D., Gearing M., Chin L.S., et al. Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated idiopathic Parkinson's and Alzheimer's diseases. J Biol Chem 2004, 279:13256-13264.
    • (2004) J Biol Chem , vol.279 , pp. 13256-13264
    • Choi, J.1    Levey, A.I.2    Weintraub, S.T.3    Rees, H.D.4    Gearing, M.5    Chin, L.S.6
  • 21
    • 0037012922 scopus 로고    scopus 로고
    • Genomewide analysis of mRNA processing in yeast using splicing-specific microarrays
    • Clark T.A., Sugnet C.W., Ares M. Genomewide analysis of mRNA processing in yeast using splicing-specific microarrays. Science 2002, 296:907-910.
    • (2002) Science , vol.296 , pp. 907-910
    • Clark, T.A.1    Sugnet, C.W.2    Ares, M.3
  • 22
    • 0037010289 scopus 로고    scopus 로고
    • Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signalling
    • Colangelo V., Schurr J., Ball M.J., Pelaez R.P., Bazan N.G., Lukiw W.J. Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signalling. J Neurosci Res 2002, 70:462-473.
    • (2002) J Neurosci Res , vol.70 , pp. 462-473
    • Colangelo, V.1    Schurr, J.2    Ball, M.J.3    Pelaez, R.P.4    Bazan, N.G.5    Lukiw, W.J.6
  • 25
    • 37149055806 scopus 로고    scopus 로고
    • Alpha7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in Alzheimer disease
    • Counts S.E., He B., Che S., Ikonomovic M.D., DeKosky S.T., Ginsberg S.D., et al. Alpha7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in Alzheimer disease. Arch Neurol 2007, 64:1771-1776.
    • (2007) Arch Neurol , vol.64 , pp. 1771-1776
    • Counts, S.E.1    He, B.2    Che, S.3    Ikonomovic, M.D.4    DeKosky, S.T.5    Ginsberg, S.D.6
  • 26
    • 4644268336 scopus 로고    scopus 로고
    • Reduction of cortical TrkA but not p75(NTR) protein in early-stage Alzheimer's disease
    • Counts S.E., Nadeem M., Wuu J., Ginsberg S.D., Saragovi H.U., Mufson E.J. Reduction of cortical TrkA but not p75(NTR) protein in early-stage Alzheimer's disease. Ann Neurol 2004, 56:520-531.
    • (2004) Ann Neurol , vol.56 , pp. 520-531
    • Counts, S.E.1    Nadeem, M.2    Wuu, J.3    Ginsberg, S.D.4    Saragovi, H.U.5    Mufson, E.J.6
  • 28
    • 0027280874 scopus 로고
    • Disrupted 1-adrenoceptor-G protein coupling in the temporal cortex of patients with Alzheimer's disease
    • Cowburn R.F., Vestling M., Fowler C.J., Ravid R., Winblad B., O'Neill C. Disrupted 1-adrenoceptor-G protein coupling in the temporal cortex of patients with Alzheimer's disease. Neurosci Lett 1993, 155:163-166.
    • (1993) Neurosci Lett , vol.155 , pp. 163-166
    • Cowburn, R.F.1    Vestling, M.2    Fowler, C.J.3    Ravid, R.4    Winblad, B.5    O'Neill, C.6
  • 29
    • 0022578631 scopus 로고
    • The selectivity of the reduction of serotonin S2 receptors in Alzheimer-type dementia
    • Cross A.J., Crow T.J., Ferrier I.N., Johnson J.A. The selectivity of the reduction of serotonin S2 receptors in Alzheimer-type dementia. Neurobiol Aging 1986, 7:3-7.
    • (1986) Neurobiol Aging , vol.7 , pp. 3-7
    • Cross, A.J.1    Crow, T.J.2    Ferrier, I.N.3    Johnson, J.A.4
  • 30
    • 0011162190 scopus 로고
    • Selective loss of central cholinergic neurons in Alzheimer's disease
    • Davies P., Maloney A.J. Selective loss of central cholinergic neurons in Alzheimer's disease. Lancet 1976, 2:1403.
    • (1976) Lancet , vol.2 , pp. 1403
    • Davies, P.1    Maloney, A.J.2
  • 31
    • 0025269152 scopus 로고
    • Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity
    • DeKosky S.T., Scheff S.W. Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity. Ann Neurol 1990, 27:457-464.
    • (1990) Ann Neurol , vol.27 , pp. 457-464
    • DeKosky, S.T.1    Scheff, S.W.2
  • 32
    • 33746104816 scopus 로고    scopus 로고
    • Transcriptome analysis reveals link between proteasomal and mitochondrial pathways in Parkinson's disease
    • Duke D.C., Moran L.B., Kalaitzakis M.E., Deprez M., Dexter D.T., Pearce R.K., et al. Transcriptome analysis reveals link between proteasomal and mitochondrial pathways in Parkinson's disease. Neurogenetics 2006, 7:139-148.
    • (2006) Neurogenetics , vol.7 , pp. 139-148
    • Duke, D.C.1    Moran, L.B.2    Kalaitzakis, M.E.3    Deprez, M.4    Dexter, D.T.5    Pearce, R.K.6
  • 33
    • 0037150687 scopus 로고    scopus 로고
    • Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease
    • Dunah A.W., Jeong H., Griffin A., Kim Y.M., Standaert D.G., Hersch S.M., et al. Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease. Science 2002, 296:2238-2243.
    • (2002) Science , vol.296 , pp. 2238-2243
    • Dunah, A.W.1    Jeong, H.2    Griffin, A.3    Kim, Y.M.4    Standaert, D.G.5    Hersch, S.M.6
  • 34
    • 34548561818 scopus 로고    scopus 로고
    • Beadarray: R classes and methods for Illumina bead-based data
    • Dunning M.J., Smith M.L., Ritchie M.E., Tavare S. Beadarray: R classes and methods for Illumina bead-based data. Bioinformatics 2007, 23:2183-2184.
    • (2007) Bioinformatics , vol.23 , pp. 2183-2184
    • Dunning, M.J.1    Smith, M.L.2    Ritchie, M.E.3    Tavare, S.4
  • 35
    • 0037126171 scopus 로고    scopus 로고
    • Nurr1-null heterozygous mice have reduced mesolimbic and mesocortical dopamine levels and increased stress-induced locomotor activity
    • Eells J.B., Lipska B.K., Yeung S.K., Misler J.A., Nikodem V.M. Nurr1-null heterozygous mice have reduced mesolimbic and mesocortical dopamine levels and increased stress-induced locomotor activity. Behav Brain Res 2002, 136:267-275.
    • (2002) Behav Brain Res , vol.136 , pp. 267-275
    • Eells, J.B.1    Lipska, B.K.2    Yeung, S.K.3    Misler, J.A.4    Nikodem, V.M.5
  • 36
    • 0024317904 scopus 로고
    • Prevalence of Alzheimer's disease in a community population of older persons: higher than previously reported
    • Evans D.A., Funkenstein H.H., Albert M.S., Scherr P.A., Cook N.R., Chown M.J., et al. Prevalence of Alzheimer's disease in a community population of older persons: higher than previously reported. JAMA 1989, 262:2551-2556.
    • (1989) JAMA , vol.262 , pp. 2551-2556
    • Evans, D.A.1    Funkenstein, H.H.2    Albert, M.S.3    Scherr, P.A.4    Cook, N.R.5    Chown, M.J.6
  • 37
    • 0025954066 scopus 로고
    • Ageing and Parkinson's disease: substantia nigra regional selectivity
    • Fearnley J.M., Lees A.J. Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 1991, 114:2283-2301.
    • (1991) Brain , vol.114 , pp. 2283-2301
    • Fearnley, J.M.1    Lees, A.J.2
  • 38
    • 57649121159 scopus 로고    scopus 로고
    • Expression profile analysis of brain aging
    • CRC Press, New York, D.R. Riddle (Ed.)
    • Ginsberg S.D. Expression profile analysis of brain aging. Brain Aging: Models, Methods and Mechanisms 2007, CRC Press, New York. D.R. Riddle (Ed.).
    • (2007) Brain Aging: Models, Methods and Mechanisms
    • Ginsberg, S.D.1
  • 39
    • 33645102446 scopus 로고    scopus 로고
    • Shift in the ratio of 3-repeat tau and 4-repeat tau mRNAs in individual cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease
    • Ginsberg S.D., Che S., Counts S.E., Mufson E.J. Shift in the ratio of 3-repeat tau and 4-repeat tau mRNAs in individual cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease. J Neurochem 2006, 96:1401-1408.
    • (2006) J Neurochem , vol.96 , pp. 1401-1408
    • Ginsberg, S.D.1    Che, S.2    Counts, S.E.3    Mufson, E.J.4
  • 40
    • 33745416559 scopus 로고    scopus 로고
    • Single cell gene expression profiling in Alzheimer's disease
    • Ginsberg S.D., Che S., Counts S.E., Mufson E.J. Single cell gene expression profiling in Alzheimer's disease. NeuroRx 2006, 3:302-318.
    • (2006) NeuroRx , vol.3 , pp. 302-318
    • Ginsberg, S.D.1    Che, S.2    Counts, S.E.3    Mufson, E.J.4
  • 41
    • 33645301867 scopus 로고    scopus 로고
    • Down regulation of trk but not p75NTR gene expression in single cholinergic basal forebrain neurons mark the progression of Alzheimer's disease
    • Ginsberg S.D., Che S., Wuu J., Counts S.E., Mufson E.J. Down regulation of trk but not p75NTR gene expression in single cholinergic basal forebrain neurons mark the progression of Alzheimer's disease. J Neurochem 2006, 97:475-487.
    • (2006) J Neurochem , vol.97 , pp. 475-487
    • Ginsberg, S.D.1    Che, S.2    Wuu, J.3    Counts, S.E.4    Mufson, E.J.5
  • 43
    • 3142680751 scopus 로고    scopus 로고
    • Single cell gene expression analysis: implications for neurodegenerative and neuropsychiatric disorders
    • Ginsberg S.D., Elarova I., Ruben M., Tan F., Counts S.E., Eberwine J.H., et al. Single cell gene expression analysis: implications for neurodegenerative and neuropsychiatric disorders. Neurochem Res 2004, 29:1054-1065.
    • (2004) Neurochem Res , vol.29 , pp. 1054-1065
    • Ginsberg, S.D.1    Elarova, I.2    Ruben, M.3    Tan, F.4    Counts, S.E.5    Eberwine, J.H.6
  • 44
  • 46
    • 0024745894 scopus 로고
    • Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease
    • Goedert M., Spillantini M.G., Jakes R., Rutherford D., Crowther R.A. Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron 1989, 3:519-526.
    • (1989) Neuron , vol.3 , pp. 519-526
    • Goedert, M.1    Spillantini, M.G.2    Jakes, R.3    Rutherford, D.4    Crowther, R.A.5
  • 47
    • 0024387161 scopus 로고
    • Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain
    • Goedert M., Spillantini M.G., Jakes R., Rutherford D., Crowther R.A. Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain. EMBO J 1989, 8:393-399.
    • (1989) EMBO J , vol.8 , pp. 393-399
    • Goedert, M.1    Spillantini, M.G.2    Jakes, R.3    Rutherford, D.4    Crowther, R.A.5
  • 48
    • 0034992339 scopus 로고    scopus 로고
    • Tau and transgenic animal models
    • Gotz J. Tau and transgenic animal models. Brain Res Brain Res Rev 2001, 35:266-286.
    • (2001) Brain Res Brain Res Rev , vol.35 , pp. 266-286
    • Gotz, J.1
  • 49
    • 11844262742 scopus 로고    scopus 로고
    • Gene expression profiling of rat midbrain dopamine neurons: implications for selective vulnerability in Parkinsonism
    • Greene J.G., Dingledine R., Greenamyre J.T. Gene expression profiling of rat midbrain dopamine neurons: implications for selective vulnerability in Parkinsonism. Neurobiol Dis 2005, 18:19-31.
    • (2005) Neurobiol Dis , vol.18 , pp. 19-31
    • Greene, J.G.1    Dingledine, R.2    Greenamyre, J.T.3
  • 50
    • 19944428747 scopus 로고    scopus 로고
    • Gene expression profiling of parkinsonian substantia nigra pars compacta; alterations in ubiquitin-proteasome, heat shock protein, iron and oxidative stress regulated proteins, cell adhesion/cellular matrix and vesicle trafficking genes
    • Grunblatt E., Mandel S., Jacob-Hirsch J., Zeligson S., Amariglo N., Rechavi G., et al. Gene expression profiling of parkinsonian substantia nigra pars compacta; alterations in ubiquitin-proteasome, heat shock protein, iron and oxidative stress regulated proteins, cell adhesion/cellular matrix and vesicle trafficking genes. J Neural Transm 2004, 111:1543-1573.
    • (2004) J Neural Transm , vol.111 , pp. 1543-1573
    • Grunblatt, E.1    Mandel, S.2    Jacob-Hirsch, J.3    Zeligson, S.4    Amariglo, N.5    Rechavi, G.6
  • 51
    • 0034941949 scopus 로고    scopus 로고
    • Gene expression analysis in N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice model of Parkinson's disease using cDNA microarray: effect of R-apomorphine
    • Grunblatt E., Mandel S., Maor G., Youdim M.B. Gene expression analysis in N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice model of Parkinson's disease using cDNA microarray: effect of R-apomorphine. J Neurochem 2001, 78:1-12.
    • (2001) J Neurochem , vol.78 , pp. 1-12
    • Grunblatt, E.1    Mandel, S.2    Maor, G.3    Youdim, M.B.4
  • 52
    • 0033983966 scopus 로고    scopus 로고
    • Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease
    • Guan Z.Z., Zhang X., Ravid R., Nordberg A. Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease. J Neurochem 2000, 74:237-243.
    • (2000) J Neurochem , vol.74 , pp. 237-243
    • Guan, Z.Z.1    Zhang, X.2    Ravid, R.3    Nordberg, A.4
  • 53
    • 0346995416 scopus 로고    scopus 로고
    • The use of real-time PCR analysis in a gene expression study of Alzheimer's disease post-mortem brains
    • Gutala R.V., Reddy P.H. The use of real-time PCR analysis in a gene expression study of Alzheimer's disease post-mortem brains. J Neurosci Methods 2004, 132:101-107.
    • (2004) J Neurosci Methods , vol.132 , pp. 101-107
    • Gutala, R.V.1    Reddy, P.H.2
  • 54
    • 0035836642 scopus 로고    scopus 로고
    • Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia
    • Hakak Y., Walker J.R., Li C., Wong W.H., Davis K.L., Buxbaum J.D. Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia. PNAS 2001, 98:4746-4751.
    • (2001) PNAS , vol.98 , pp. 4746-4751
    • Hakak, Y.1    Walker, J.R.2    Li, C.3    Wong, W.H.4    Davis, K.L.5    Buxbaum, J.D.6
  • 55
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
    • Hardy J., Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002, 297:353-356.
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 56
    • 18544401772 scopus 로고    scopus 로고
    • Up-regulation of calcineurin Abeta mRNA in the Alzheimer's disease brain: assessment by cDNA microarray
    • Hata R., Masumura M., Akatsu H., Li F., Fujita H., Nagai Y., et al. Up-regulation of calcineurin Abeta mRNA in the Alzheimer's disease brain: assessment by cDNA microarray. Biochem Biophys Res Commun 2001, 284:310-316.
    • (2001) Biochem Biophys Res Commun , vol.284 , pp. 310-316
    • Hata, R.1    Masumura, M.2    Akatsu, H.3    Li, F.4    Fujita, H.5    Nagai, Y.6
  • 57
    • 20844436594 scopus 로고    scopus 로고
    • Expression profiling of substantia nigra in Parkinson disease, progressive supranuclear palsy, and frontotemporal dementia in parkinsonism
    • Hauser M.A., Li Y.J., Xu H., Noureddine M.A., Shao Y.S., Gullans S.R., et al. Expression profiling of substantia nigra in Parkinson disease, progressive supranuclear palsy, and frontotemporal dementia in parkinsonism. Arch Neurol 2005, 62:917-921.
    • (2005) Arch Neurol , vol.62 , pp. 917-921
    • Hauser, M.A.1    Li, Y.J.2    Xu, H.3    Noureddine, M.A.4    Shao, Y.S.5    Gullans, S.R.6
  • 59
    • 0035830695 scopus 로고    scopus 로고
    • Altered expression of a-type but not b-type synapsin isoform in the brain of patients at high risk for Alzheimer's disease assessed by DNA microarray technique
    • Ho L., Guo Y., Spielman L., Petrescu O., Haroutunian V., Purohit D., et al. Altered expression of a-type but not b-type synapsin isoform in the brain of patients at high risk for Alzheimer's disease assessed by DNA microarray technique. Neurosci Lett 2001, 298:91-194.
    • (2001) Neurosci Lett , vol.298 , pp. 91-194
    • Ho, L.1    Guo, Y.2    Spielman, L.3    Petrescu, O.4    Haroutunian, V.5    Purohit, D.6
  • 60
    • 33644783812 scopus 로고    scopus 로고
    • Regional and cellular gene expression changes in human Huntington's disease brain
    • Hodges A., Strand A.D., Aragaki A.K., Kuhn A., Sengstag T., Hughes G., et al. Regional and cellular gene expression changes in human Huntington's disease brain. Hum Mol Genet 2006, 15:965-977.
    • (2006) Hum Mol Genet , vol.15 , pp. 965-977
    • Hodges, A.1    Strand, A.D.2    Aragaki, A.K.3    Kuhn, A.4    Sengstag, T.5    Hughes, G.6
  • 61
    • 0021145680 scopus 로고
    • Alzheimer's disease: cell-specific pathology isolates the hippocampal formation
    • Hyman B.T., Van Hoesen G.W., Damasio A.R., Barnes C.L. Alzheimer's disease: cell-specific pathology isolates the hippocampal formation. Science 1984, 225:1168-1170.
    • (1984) Science , vol.225 , pp. 1168-1170
    • Hyman, B.T.1    Van Hoesen, G.W.2    Damasio, A.R.3    Barnes, C.L.4
  • 62
    • 0022535539 scopus 로고
    • Perforant pathway changes and the memory impairment of Alzheimer's disease
    • Hyman B.T., Van Hoesen G.W., Kromer L.J., Damasio A.R. Perforant pathway changes and the memory impairment of Alzheimer's disease. Ann Neurol 1986, 20:472-481.
    • (1986) Ann Neurol , vol.20 , pp. 472-481
    • Hyman, B.T.1    Van Hoesen, G.W.2    Kromer, L.J.3    Damasio, A.R.4
  • 63
    • 0029554331 scopus 로고
    • AMPA-selective glutamate receptor subtype immunoreactivity in the hippocampal formation of patients with Alzheimer's disease
    • Ikonomovic M.D., Sheffield R., Armstrong D.M. AMPA-selective glutamate receptor subtype immunoreactivity in the hippocampal formation of patients with Alzheimer's disease. Hippocampus 1995, 5:469-486.
    • (1995) Hippocampus , vol.5 , pp. 469-486
    • Ikonomovic, M.D.1    Sheffield, R.2    Armstrong, D.M.3
  • 64
    • 7244245762 scopus 로고    scopus 로고
    • International Human Genome Sequencing Consortium. " Finishing the euchromatic sequence of the human genome." Nature
    • International Human Genome Sequencing Consortium. " Finishing the euchromatic sequence of the human genome." Nature 2004;431:931-45.
    • (2004) , vol.431 , pp. 931-45
  • 66
    • 34548856202 scopus 로고    scopus 로고
    • A microarray analysis of laser capture microdissected substantia nigra pars compacta after a single administration of MPTP in common marmosets
    • Iwata S., Nomoto M., Miyata A. A microarray analysis of laser capture microdissected substantia nigra pars compacta after a single administration of MPTP in common marmosets. Nihon Shinkei Seishin Yakurigaku Zasshi 2007, 27:161-166.
    • (2007) Nihon Shinkei Seishin Yakurigaku Zasshi , vol.27 , pp. 161-166
    • Iwata, S.1    Nomoto, M.2    Miyata, A.3
  • 67
    • 33847725506 scopus 로고    scopus 로고
    • Alterations in expression of glutamatergic transporters and receptors in sporadic Alzheimer's disease
    • Jacob C.P., Koutsilieri E., Bartl J., Neuen-Jacob E., Arzberger T., Zander N., et al. Alterations in expression of glutamatergic transporters and receptors in sporadic Alzheimer's disease. J Alzheimers Dis 2007, 11:97-116.
    • (2007) J Alzheimers Dis , vol.11 , pp. 97-116
    • Jacob, C.P.1    Koutsilieri, E.2    Bartl, J.3    Neuen-Jacob, E.4    Arzberger, T.5    Zander, N.6
  • 68
    • 84889444838 scopus 로고    scopus 로고
    • editor. Next-generation genome sequencing - towards personalized medicine. Weinheim: Wiley-VCH;
    • Janitz M, editor. Next-generation genome sequencing - towards personalized medicine. Weinheim: Wiley-VCH; 2008.
    • (2008)
    • Janitz, M.1
  • 69
    • 0030668729 scopus 로고    scopus 로고
    • Multivariate analysis of RNA levels from postmortem human brains as measured by three different methods of RT-PCR. Stanley Neuropathology Consortium
    • Johnston N.L., Cervenak J., Shore A.D., Torrey E.F., Yolken R.H. Multivariate analysis of RNA levels from postmortem human brains as measured by three different methods of RT-PCR. Stanley Neuropathology Consortium. J. Neurosci Methods 1997, 77:83-92.
    • (1997) J. Neurosci Methods , vol.77 , pp. 83-92
    • Johnston, N.L.1    Cervenak, J.2    Shore, A.D.3    Torrey, E.F.4    Yolken, R.H.5
  • 70
    • 0027242002 scopus 로고
    • Dopamine D2 receptors in the hippocampus and amygdala in Alzheimer's disease
    • Joyce J.N., Kaeger C., Ryoo H., Goldsmith S. Dopamine D2 receptors in the hippocampus and amygdala in Alzheimer's disease. Neurosci Lett 1993, 154:171-174.
    • (1993) Neurosci Lett , vol.154 , pp. 171-174
    • Joyce, J.N.1    Kaeger, C.2    Ryoo, H.3    Goldsmith, S.4
  • 71
    • 7744245590 scopus 로고    scopus 로고
    • Comparison of microarray-based mRNA profiling technologies for identification of psychiatric disease and drug signatures
    • Jurata L.W., Bukhman Y.V., Charles V., Capriglione F., Bullard J., Lemire A.L., et al. Comparison of microarray-based mRNA profiling technologies for identification of psychiatric disease and drug signatures. J Neurosci Methods 2004, 138:173-188.
    • (2004) J Neurosci Methods , vol.138 , pp. 173-188
    • Jurata, L.W.1    Bukhman, Y.V.2    Charles, V.3    Capriglione, F.4    Bullard, J.5    Lemire, A.L.6
  • 72
    • 0034044227 scopus 로고    scopus 로고
    • Neurotrophin signal transduction in the nervous system
    • Kaplan D.R., Miller F.D. Neurotrophin signal transduction in the nervous system. Curr Opin Neurobiol 2000, 10:381-391.
    • (2000) Curr Opin Neurobiol , vol.10 , pp. 381-391
    • Kaplan, D.R.1    Miller, F.D.2
  • 73
    • 34548853750 scopus 로고    scopus 로고
    • Exon arrays provide accurate assessments of gene expression
    • Kapur K., Xing Y., Ouyang Z., Wong W.H. Exon arrays provide accurate assessments of gene expression. Genome Biol 2007, 8:R82.
    • (2007) Genome Biol , vol.8
    • Kapur, K.1    Xing, Y.2    Ouyang, Z.3    Wong, W.H.4
  • 74
    • 2342533801 scopus 로고    scopus 로고
    • Reliability of gene expression ratios for cDNA microarrays in multiconditional experiments with a reference design
    • Konig R., Baldessari D., Pollet N., Niehrs C., Eils R. Reliability of gene expression ratios for cDNA microarrays in multiconditional experiments with a reference design. Nucleic Acids Res 2004, 32:e29.
    • (2004) Nucleic Acids Res , vol.32
    • Konig, R.1    Baldessari, D.2    Pollet, N.3    Niehrs, C.4    Eils, R.5
  • 75
    • 33846000337 scopus 로고    scopus 로고
    • Immunohistochemical localization of dopamine receptor subtypes (D1R-D5R) in Alzheimer's disease brain
    • Kumar U., Patel S.C. Immunohistochemical localization of dopamine receptor subtypes (D1R-D5R) in Alzheimer's disease brain. Brain Res 2007, 1131:187-196.
    • (2007) Brain Res , vol.1131 , pp. 187-196
    • Kumar, U.1    Patel, S.C.2
  • 76
    • 0642316039 scopus 로고    scopus 로고
    • Nerve growth factor: structure, function and therapeutic implications for Alzheimer's disease
    • Lad S.P., Neet K.E., Mufson E.J. Nerve growth factor: structure, function and therapeutic implications for Alzheimer's disease. Curr Drug Target CNS Neurol Disord 2003, 2:315-334.
    • (2003) Curr Drug Target CNS Neurol Disord , vol.2 , pp. 315-334
    • Lad, S.P.1    Neet, K.E.2    Mufson, E.J.3
  • 77
    • 0035845705 scopus 로고    scopus 로고
    • Psychosis of Alzheimer's disease is associated with elevated muscarinic M2 binding in the cortex
    • Lai M.K., Lai O.F., Keene J., Esiri M.M., Francis P.T., Hope T., et al. Psychosis of Alzheimer's disease is associated with elevated muscarinic M2 binding in the cortex. Neurology 2001, 57:805-811.
    • (2001) Neurology , vol.57 , pp. 805-811
    • Lai, M.K.1    Lai, O.F.2    Keene, J.3    Esiri, M.M.4    Francis, P.T.5    Hope, T.6
  • 78
    • 18744402189 scopus 로고    scopus 로고
    • Loss of serotonin 5-HT2A receptors in the postmortem temporal cortex correlates with rate of cognitive decline in Alzheimer's disease
    • Lai M.K., Tsang S.W., Alder J.T., Keene J., Hope T., Esiri M.M., et al. Loss of serotonin 5-HT2A receptors in the postmortem temporal cortex correlates with rate of cognitive decline in Alzheimer's disease. Psychopharmacology 2005, 179:673-677.
    • (2005) Psychopharmacology , vol.179 , pp. 673-677
    • Lai, M.K.1    Tsang, S.W.2    Alder, J.T.3    Keene, J.4    Hope, T.5    Esiri, M.M.6
  • 79
    • 55549097836 scopus 로고    scopus 로고
    • Mapping short DNA sequencing reads and calling variants using mapping quality scores
    • Li H., Ruan J., Durbin R. Mapping short DNA sequencing reads and calling variants using mapping quality scores. Genome Res 2008, 18:1851-1858.
    • (2008) Genome Res , vol.18 , pp. 1851-1858
    • Li, H.1    Ruan, J.2    Durbin, R.3
  • 80
    • 40049104732 scopus 로고    scopus 로고
    • SOAP: short oligonucleotide alignment program
    • Li R., Li Y., Kristiansen K., Wang J. SOAP: short oligonucleotide alignment program. Bioinformatics 2008, 24:713-714.
    • (2008) Bioinformatics , vol.24 , pp. 713-714
    • Li, R.1    Li, Y.2    Kristiansen, K.3    Wang, J.4
  • 81
    • 70449389190 scopus 로고    scopus 로고
    • Microarray platform consistency is revealed by biologically functional analysis of gene expression profiles
    • Li Z., Su Z., Wen Z., Shi L., Chen T. Microarray platform consistency is revealed by biologically functional analysis of gene expression profiles. BMC Bioinformatics 2009, 10:S12.
    • (2009) BMC Bioinformatics , vol.10
    • Li, Z.1    Su, Z.2    Wen, Z.3    Shi, L.4    Chen, T.5
  • 82
    • 27644478606 scopus 로고    scopus 로고
    • Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation
    • Liu F., Grundke-Iqbal I., Iqbal K., Gong C.X. Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation. Eur J Neurosci 2005, 22:1942-1950.
    • (2005) Eur J Neurosci , vol.22 , pp. 1942-1950
    • Liu, F.1    Grundke-Iqbal, I.2    Iqbal, K.3    Gong, C.X.4
  • 83
    • 34748897213 scopus 로고    scopus 로고
    • Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1
    • Liu Q., Zerbinatti C.V., Zhang J., Hoe H.S., Wang B., Cole S.L., et al. Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1. Neuron 2007, 56:66-78.
    • (2007) Neuron , vol.56 , pp. 66-78
    • Liu, Q.1    Zerbinatti, C.V.2    Zhang, J.3    Hoe, H.S.4    Wang, B.5    Cole, S.L.6
  • 84
    • 0037131567 scopus 로고    scopus 로고
    • The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility
    • Liu Y., Fallon L., Lashuel H.A., Liu Z., Lansbury P.T. The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility. Cell 2002, 111:209-218.
    • (2002) Cell , vol.111 , pp. 209-218
    • Liu, Y.1    Fallon, L.2    Lashuel, H.A.3    Liu, Z.4    Lansbury, P.T.5
  • 87
    • 0037101835 scopus 로고    scopus 로고
    • Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain
    • Luthi-Carter R., Hanson S.A., Strand A.D., Bergstrom D.A., Chun W., Peters N.L., et al. Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain. Hum Mol Genet 2002, 11:1911-1926.
    • (2002) Hum Mol Genet , vol.11 , pp. 1911-1926
    • Luthi-Carter, R.1    Hanson, S.A.2    Strand, A.D.3    Bergstrom, D.A.4    Chun, W.5    Peters, N.L.6
  • 89
    • 0037101837 scopus 로고    scopus 로고
    • Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects
    • Luthi-Carter R., Strand A.D., Hanson S.A., Kooperberg C., Schilling G., La Spada A.R., et al. Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects. Hum Mol Genet 2002, 11:1927-1937.
    • (2002) Hum Mol Genet , vol.11 , pp. 1927-1937
    • Luthi-Carter, R.1    Strand, A.D.2    Hanson, S.A.3    Kooperberg, C.4    Schilling, G.5    La Spada, A.R.6
  • 90
    • 29744442267 scopus 로고    scopus 로고
    • Gene expression profiling of sporadic Parkinson's disease substantia nigra pars compacta reveals impairment of ubiquitin-proteasome subunits, SKP1A, aldehyde dehydrogenase, and chaperone HSC-70
    • Mandel S., Grunblatt E., Riederer P., Amariglio N., Jacob-Hirsch J., Rechavi G., et al. Gene expression profiling of sporadic Parkinson's disease substantia nigra pars compacta reveals impairment of ubiquitin-proteasome subunits, SKP1A, aldehyde dehydrogenase, and chaperone HSC-70. Ann N Y Acad Sci 2005, 1053:356-375.
    • (2005) Ann N Y Acad Sci , vol.1053 , pp. 356-375
    • Mandel, S.1    Grunblatt, E.2    Riederer, P.3    Amariglio, N.4    Jacob-Hirsch, J.5    Rechavi, G.6
  • 91
    • 0037386720 scopus 로고    scopus 로고
    • Using cDNA microarray to assess Parkinson's disease models and the effects of neuroprotective drugs
    • Mandel S., Weinreb O., Youdim M. Using cDNA microarray to assess Parkinson's disease models and the effects of neuroprotective drugs. Trends Pharmacol Sci 2003, 24:184-191.
    • (2003) Trends Pharmacol Sci , vol.24 , pp. 184-191
    • Mandel, S.1    Weinreb, O.2    Youdim, M.3
  • 93
    • 0032031780 scopus 로고    scopus 로고
    • Increased peroxidation and reduced antioxidant enzyme activity in Alzheimer's disease
    • Marcus D.L., Thomas C., Rodriguez C., Simberkoff K., Tsai J.S., Strafaci J.A., et al. Increased peroxidation and reduced antioxidant enzyme activity in Alzheimer's disease. Exp Neurol 1998, 150:40-44.
    • (1998) Exp Neurol , vol.150 , pp. 40-44
    • Marcus, D.L.1    Thomas, C.2    Rodriguez, C.3    Simberkoff, K.4    Tsai, J.S.5    Strafaci, J.A.6
  • 96
    • 0030813929 scopus 로고    scopus 로고
    • Selective destruction of stable microtubules and axons by inhibitors of protein serine/threonine phosphatases in cultured human neurons
    • Merrick S.E., Trojanowski J.Q., Lee V.M.-Y. Selective destruction of stable microtubules and axons by inhibitors of protein serine/threonine phosphatases in cultured human neurons. J Neurosci 1997, 17:5726-5737.
    • (1997) J Neurosci , vol.17 , pp. 5726-5737
    • Merrick, S.E.1    Trojanowski, J.Q.2    Lee, V.M.-Y.3
  • 97
    • 78049390783 scopus 로고    scopus 로고
    • MIAME. Viewed July 13 2010, .
    • MIAME. 2009. Viewed July 13 2010, http://www.mged.org/Workgroups/MIAME/miame.html.
    • (2009)
  • 98
    • 38949175007 scopus 로고    scopus 로고
    • A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging
    • Miller J.A., Oldham M.C., Geschwind D.H. A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging. J Neurosci 2008, 28:1410-1420.
    • (2008) J Neurosci , vol.28 , pp. 1410-1420
    • Miller, J.A.1    Oldham, M.C.2    Geschwind, D.H.3
  • 99
    • 4444368405 scopus 로고    scopus 로고
    • Dysregulation of gene expression in the 1-methyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-lesioned mouse substantia nigra
    • Miller R.M., Callahan L.M., Casaceli C., Chen L., Kiser G.L., Chui B., et al. Dysregulation of gene expression in the 1-methyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-lesioned mouse substantia nigra. J Neurosci 2004, 24:7445-7454.
    • (2004) J Neurosci , vol.24 , pp. 7445-7454
    • Miller, R.M.1    Callahan, L.M.2    Casaceli, C.3    Chen, L.4    Kiser, G.L.5    Chui, B.6
  • 101
    • 10644247621 scopus 로고    scopus 로고
    • Application of DNA tiling arrays for whole-genome analysis
    • Mockler T.C., Ecker J.R. Application of DNA tiling arrays for whole-genome analysis. Genomics 2005, 85:1-15.
    • (2005) Genomics , vol.85 , pp. 1-15
    • Mockler, T.C.1    Ecker, J.R.2
  • 103
    • 0024449354 scopus 로고
    • Loss of nerve growth factor receptor-containing neurons in Alzheimer's disease: a quantitative analysis across subregions of the basal forebrain
    • Mufson E.J., Bothwell M., Kordower J.H. Loss of nerve growth factor receptor-containing neurons in Alzheimer's disease: a quantitative analysis across subregions of the basal forebrain. Exp Neurol 1989, 105:221-232.
    • (1989) Exp Neurol , vol.105 , pp. 221-232
    • Mufson, E.J.1    Bothwell, M.2    Kordower, J.H.3
  • 104
    • 33749237719 scopus 로고    scopus 로고
    • Neuronal gene expression profiling: uncovering the molecular biology of neurodegenerative disease
    • Mufson E.J., Counts S.E., Che S., Ginsberg S.D. Neuronal gene expression profiling: uncovering the molecular biology of neurodegenerative disease. Prog Brain Res 2006, 159:197-222.
    • (2006) Prog Brain Res , vol.159 , pp. 197-222
    • Mufson, E.J.1    Counts, S.E.2    Che, S.3    Ginsberg, S.D.4
  • 105
    • 0036808469 scopus 로고    scopus 로고
    • Gene expression profiles of cholinergic nucleus basalis neurons in Alzheimer's disease
    • Mufson E.J., Counts S.E., Ginsberg S.D. Gene expression profiles of cholinergic nucleus basalis neurons in Alzheimer's disease. Neurochem Res 2002, 27:1035-1048.
    • (2002) Neurochem Res , vol.27 , pp. 1035-1048
    • Mufson, E.J.1    Counts, S.E.2    Ginsberg, S.D.3
  • 106
    • 0043025510 scopus 로고    scopus 로고
    • Preservation of brain nerve growth factor in mild cognitive impairment and Alzheimer disease
    • Mufson E.J., Ikonomovic M.D., Styren S.D., Counts S.E., Wuu J., Leurgans S., et al. Preservation of brain nerve growth factor in mild cognitive impairment and Alzheimer disease. Arch Neurol 2003, 60:1143-1148.
    • (2003) Arch Neurol , vol.60 , pp. 1143-1148
    • Mufson, E.J.1    Ikonomovic, M.D.2    Styren, S.D.3    Counts, S.E.4    Wuu, J.5    Leurgans, S.6
  • 107
    • 0025261742 scopus 로고
    • The unusual origin of the polymerase chain reaction
    • Mullis K.B. The unusual origin of the polymerase chain reaction. Sci Am 1990, 262:56-65.
    • (1990) Sci Am , vol.262 , pp. 56-65
    • Mullis, K.B.1
  • 108
    • 45549088326 scopus 로고    scopus 로고
    • The transcriptional landscape of the yeast genome defined by RNA sequencing
    • Nagalakshmi U., Wang Z., Waern K., Shou C., Raha D., Gerstein M., et al. The transcriptional landscape of the yeast genome defined by RNA sequencing. Science 2008, 320:1344-1349.
    • (2008) Science , vol.320 , pp. 1344-1349
    • Nagalakshmi, U.1    Wang, Z.2    Waern, K.3    Shou, C.4    Raha, D.5    Gerstein, M.6
  • 109
    • 0036408413 scopus 로고    scopus 로고
    • Experimental Parkinsonism modulates multiple genes involved in the transduction of dopaminergic signals in the striatum
    • Napolitano M., Centonze D., Calce A., Picconi B., Spiezia S., Gulino A., et al. Experimental Parkinsonism modulates multiple genes involved in the transduction of dopaminergic signals in the striatum. Neurobiol Dis 2002, 10:387-395.
    • (2002) Neurobiol Dis , vol.10 , pp. 387-395
    • Napolitano, M.1    Centonze, D.2    Calce, A.3    Picconi, B.4    Spiezia, S.5    Gulino, A.6
  • 110
    • 78049385037 scopus 로고    scopus 로고
    • Gene profile of electroconvulsive seizures: induction of neurotrophic and angiogenic factors
    • Newton S.S., Collier E.F., Hunsberger J., Adams D., Terwilliger R., Selvanayagam E., et al. Gene profile of electroconvulsive seizures: induction of neurotrophic and angiogenic factors. J Neurosci 2003, 15:7539-7547.
    • (2003) J Neurosci , vol.15 , pp. 7539-7547
    • Newton, S.S.1    Collier, E.F.2    Hunsberger, J.3    Adams, D.4    Terwilliger, R.5    Selvanayagam, E.6
  • 111
    • 0028815653 scopus 로고
    • Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressent drug treatments
    • Nibuya M., Morinobu S., Duman R.S. Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressent drug treatments. J Neurosci 1995, 15:7539-7547.
    • (1995) J Neurosci , vol.15 , pp. 7539-7547
    • Nibuya, M.1    Morinobu, S.2    Duman, R.S.3
  • 112
    • 0038689162 scopus 로고    scopus 로고
    • Cdk5 is a key factor in tau aggregation and tangle formation in vivo
    • Noble W., Olm V., Takata K., Casey E., Mary O., Meyerson J., et al. Cdk5 is a key factor in tau aggregation and tangle formation in vivo. Neuron 2003, 38:555-565.
    • (2003) Neuron , vol.38 , pp. 555-565
    • Noble, W.1    Olm, V.2    Takata, K.3    Casey, E.4    Mary, O.5    Meyerson, J.6
  • 113
    • 0035937523 scopus 로고    scopus 로고
    • Interference by huntingtin and atrophin-1 with CBP-mediated transcription leading to cellular toxicity
    • Nucifora F.C., Sasaki M., Peters M.F., Huang H., Cooper J.K., Yamada M., et al. Interference by huntingtin and atrophin-1 with CBP-mediated transcription leading to cellular toxicity. Science 2001, 291:2423-2428.
    • (2001) Science , vol.291 , pp. 2423-2428
    • Nucifora, F.C.1    Sasaki, M.2    Peters, M.F.3    Huang, H.4    Cooper, J.K.5    Yamada, M.6
  • 114
    • 55949131727 scopus 로고    scopus 로고
    • Gene expression profiles of mouse striatum in control and maneb+paraquat-induced Parkinson's disease phenotype: validation of differentially expressed energy metabolizing transcripts
    • Patel S., Singh K., Singh S., Singh M.P. Gene expression profiles of mouse striatum in control and maneb+paraquat-induced Parkinson's disease phenotype: validation of differentially expressed energy metabolizing transcripts. Mol Biotechnol 2008, 40:59-68.
    • (2008) Mol Biotechnol , vol.40 , pp. 59-68
    • Patel, S.1    Singh, K.2    Singh, S.3    Singh, M.P.4
  • 115
    • 0030560897 scopus 로고    scopus 로고
    • Antisense RNA amplification: a linear amplification method for analyzing the mRNA population from single living cells
    • Phillips J., Eberwine J.H. Antisense RNA amplification: a linear amplification method for analyzing the mRNA population from single living cells. Methods Enzymol Suppl 1996, 10:283-288.
    • (1996) Methods Enzymol Suppl , vol.10 , pp. 283-288
    • Phillips, J.1    Eberwine, J.H.2
  • 117
    • 3142745187 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress
    • Prabakaran S., Swatt J.E., Ryan M.M., Huffaker S.J., Huang J.T., Griffin J.L., et al. Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress. Mol Psychiatry 2004, 9:684-697.
    • (2004) Mol Psychiatry , vol.9 , pp. 684-697
    • Prabakaran, S.1    Swatt, J.E.2    Ryan, M.M.3    Huffaker, S.J.4    Huang, J.T.5    Griffin, J.L.6
  • 118
    • 0031921466 scopus 로고    scopus 로고
    • Mutant genes in familial Alzheimer's disease and transgenic models
    • Price D.L., Sisodia S.S. Mutant genes in familial Alzheimer's disease and transgenic models. Annu Rev Neurosci 1998, 21:479-505.
    • (1998) Annu Rev Neurosci , vol.21 , pp. 479-505
    • Price, D.L.1    Sisodia, S.S.2
  • 119
    • 0028133319 scopus 로고
    • Loss of dopamine D2 receptors varies along the rostrocaudal axis of the hippocampal complex in Alzheimer's disease
    • Ryoo H.L., Joyce J.N. Loss of dopamine D2 receptors varies along the rostrocaudal axis of the hippocampal complex in Alzheimer's disease. J Comp Neurol 1994, 348:94-110.
    • (1994) J Comp Neurol , vol.348 , pp. 94-110
    • Ryoo, H.L.1    Joyce, J.N.2
  • 120
    • 0033922730 scopus 로고    scopus 로고
    • Evolution of Alzheimer's disease-related cytoskeletal changes in the basal nucleus of Meynert
    • Sassin I., Schultz C., Thal D.R., Rub U., Arai K., Braak E., et al. Evolution of Alzheimer's disease-related cytoskeletal changes in the basal nucleus of Meynert. Acta Neuropathol (Berl) 2000, 100:259-269.
    • (2000) Acta Neuropathol (Berl) , vol.100 , pp. 259-269
    • Sassin, I.1    Schultz, C.2    Thal, D.R.3    Rub, U.4    Arai, K.5    Braak, E.6
  • 121
    • 0345276568 scopus 로고    scopus 로고
    • Synaptic pathology in Alzheimer's disease: a review of ultrastructural studies
    • Scheff S.W., Price D.A. Synaptic pathology in Alzheimer's disease: a review of ultrastructural studies. Neurobiol Aging 2003, 24:1029-1046.
    • (2003) Neurobiol Aging , vol.24 , pp. 1029-1046
    • Scheff, S.W.1    Price, D.A.2
  • 122
    • 0034910345 scopus 로고    scopus 로고
    • Navigating gene expression using microarrays - a technology review
    • Schulze A., Downward J. Navigating gene expression using microarrays - a technology review. Nat Cell Biol 2001, 3:190-195.
    • (2001) Nat Cell Biol , vol.3 , pp. 190-195
    • Schulze, A.1    Downward, J.2
  • 123
    • 67349158815 scopus 로고    scopus 로고
    • Variations in the neuropathology of familial Alzheimer's disease
    • Shepherd C., McCann H., Halliday G.M. Variations in the neuropathology of familial Alzheimer's disease. Acta Neuropathol 2009, 118:37-52.
    • (2009) Acta Neuropathol , vol.118 , pp. 37-52
    • Shepherd, C.1    McCann, H.2    Halliday, G.M.3
  • 124
    • 0037174618 scopus 로고    scopus 로고
    • Alzheimer's disease is a synaptic failure
    • Selkoe D.J. Alzheimer's disease is a synaptic failure. Science 2002, 298:789-791.
    • (2002) Science , vol.298 , pp. 789-791
    • Selkoe, D.J.1
  • 125
    • 33748491517 scopus 로고    scopus 로고
    • The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements
    • Shi L., Reid L.H., Jones W.D., Shippy R., Warrington J.A., Baker S.C., et al. The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements. Nat Biotechnol 2006, 24:1151-1161.
    • (2006) Nat Biotechnol , vol.24 , pp. 1151-1161
    • Shi, L.1    Reid, L.H.2    Jones, W.D.3    Shippy, R.4    Warrington, J.A.5    Baker, S.C.6
  • 126
    • 0033818112 scopus 로고    scopus 로고
    • Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription
    • Shimohata T., Nakajima T., Yamada M., Uchida C., Onodera O., Naruse S., et al. Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription. Nat Genet 2000, 26:29-36.
    • (2000) Nat Genet , vol.26 , pp. 29-36
    • Shimohata, T.1    Nakajima, T.2    Yamada, M.3    Uchida, C.4    Onodera, O.5    Naruse, S.6
  • 128
    • 0033634890 scopus 로고    scopus 로고
    • Pathology of early-onset Alzheimer's disease cases bearing the Thr113-114ins presenilin-1 mutation
    • Singleton A.B., Hall R., Ballard C.G., Perry R.H., Xuereb J.H., Rubinsztein D.C., et al. Pathology of early-onset Alzheimer's disease cases bearing the Thr113-114ins presenilin-1 mutation. Brain 2000, 123:2467-2474.
    • (2000) Brain , vol.123 , pp. 2467-2474
    • Singleton, A.B.1    Hall, R.2    Ballard, C.G.3    Perry, R.H.4    Xuereb, J.H.5    Rubinsztein, D.C.6
  • 129
    • 41249096306 scopus 로고    scopus 로고
    • Using mapping quality scores and longer reads improves accuracy of Solexa read mapping
    • Smith A.D., Xuan Z., Zhang M.Q. Using mapping quality scores and longer reads improves accuracy of Solexa read mapping. BMC Bioinformatics 2008, 9:128.
    • (2008) BMC Bioinformatics , vol.9 , pp. 128
    • Smith, A.D.1    Xuan, Z.2    Zhang, M.Q.3
  • 130
    • 0034941330 scopus 로고    scopus 로고
    • Nerve growth factor signaling, neuroprotection, and neural repair
    • Sofroniew M.V., Howe C.L., Mobley W.C. Nerve growth factor signaling, neuroprotection, and neural repair. Annu Rev Neurosci 2001, 24:1217-1281.
    • (2001) Annu Rev Neurosci , vol.24 , pp. 1217-1281
    • Sofroniew, M.V.1    Howe, C.L.2    Mobley, W.C.3
  • 132
    • 0037408279 scopus 로고    scopus 로고
    • Transcriptional abnormalities in Huntington disease
    • Sugars K.L., Rubinsztein D.C. Transcriptional abnormalities in Huntington disease. Trends Gen 2003, 19:233-237.
    • (2003) Trends Gen , vol.19 , pp. 233-237
    • Sugars, K.L.1    Rubinsztein, D.C.2
  • 134
    • 0034656234 scopus 로고    scopus 로고
    • Selective regional loss of exocytotic presynaptic vesicle proteins in Alzheimer's disease brains
    • Sze C.I., Bi H., Kleinschmidt-DeMasters B.K., Filley C.M., Martin L.J. Selective regional loss of exocytotic presynaptic vesicle proteins in Alzheimer's disease brains. J Neurol Sci 2000, 175:81-90.
    • (2000) J Neurol Sci , vol.175 , pp. 81-90
    • Sze, C.I.1    Bi, H.2    Kleinschmidt-DeMasters, B.K.3    Filley, C.M.4    Martin, L.J.5
  • 135
    • 0030872413 scopus 로고    scopus 로고
    • Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer disease
    • Sze C.I., Troncoso J.C., Kawas C., Mouton P., Price D.L., Martin L.J. Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer disease. J Neuropathol Exp Neurol 1997, 56:933-944.
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 933-944
    • Sze, C.I.1    Troncoso, J.C.2    Kawas, C.3    Mouton, P.4    Price, D.L.5    Martin, L.J.6
  • 136
    • 0035816492 scopus 로고    scopus 로고
    • Three novel alternatively spliced isoforms of the human beta-site amyloid precursor protein cleaving enzyme (BACE) and their effect on amyloid beta-peptide production
    • Tanahashi H., Tabira T. Three novel alternatively spliced isoforms of the human beta-site amyloid precursor protein cleaving enzyme (BACE) and their effect on amyloid beta-peptide production. Neurosci Lett 2001, 307:9-12.
    • (2001) Neurosci Lett , vol.307 , pp. 9-12
    • Tanahashi, H.1    Tabira, T.2
  • 137
    • 0042668370 scopus 로고    scopus 로고
    • Identification of a novel alternative splicing isoform of human amyloid precursor protein gene APP639
    • Tang K., Wang C., Shen C., Sheng S., Ravid R., Jing N. Identification of a novel alternative splicing isoform of human amyloid precursor protein gene APP639. Eur J Neurosci 2003, 18:102-108.
    • (2003) Eur J Neurosci , vol.18 , pp. 102-108
    • Tang, K.1    Wang, C.2    Shen, C.3    Sheng, S.4    Ravid, R.5    Jing, N.6
  • 138
    • 1642540257 scopus 로고    scopus 로고
    • Neurotrophins and their receptors: signaling trios in complex biological systems
    • Teng K.K., Hempstead B.L. Neurotrophins and their receptors: signaling trios in complex biological systems. Cell Mol Life Sci 2004, 61:35-48.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 35-48
    • Teng, K.K.1    Hempstead, B.L.2
  • 139
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: discovering splice junctions with RNA-Seq
    • Trapnell C., Pachter L., Salzberg S.L. TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 2009, 25:1105-1111.
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 140
    • 77952123055 scopus 로고    scopus 로고
    • Transcript assembly and quantification by RNA-Seq revels unannotated transcripts and isoform switching during cell differentiation
    • Trapnell C., Williams B.A., Pertea G., Mortazavi A., Kwan G., van Baren M.J., et al. Transcript assembly and quantification by RNA-Seq revels unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol 2010, 28:511-515.
    • (2010) Nat Biotechnol , vol.28 , pp. 511-515
    • Trapnell, C.1    Williams, B.A.2    Pertea, G.3    Mortazavi, A.4    Kwan, G.5    van Baren, M.J.6
  • 141
    • 0031910093 scopus 로고    scopus 로고
    • Aggregation of neurofilament and alpha-synuclein proteins in Lewy bodies: implications for the pathogenesis of Parkinson disease and Lewy body dementia
    • Trojanowski J.Q., Lee V.M.-Y. Aggregation of neurofilament and alpha-synuclein proteins in Lewy bodies: implications for the pathogenesis of Parkinson disease and Lewy body dementia. Arch Neurol 1998, 55:151-152.
    • (1998) Arch Neurol , vol.55 , pp. 151-152
    • Trojanowski, J.Q.1    Lee, V.M.-Y.2
  • 142
    • 27544494624 scopus 로고    scopus 로고
    • The Alzheimer's brain: finding out what's broken tells us how to fix it
    • Trojanowski J.Q., Lee V.M.-Y. The Alzheimer's brain: finding out what's broken tells us how to fix it. Am J Pathol 2005, 167:1183-1188.
    • (2005) Am J Pathol , vol.167 , pp. 1183-1188
    • Trojanowski, J.Q.1    Lee, V.M.-Y.2
  • 143
    • 34447578937 scopus 로고    scopus 로고
    • Disrupted muscarinic M1 receptor signaling correlates with loss of protein kinase C activity and glutamatergic deficit in Alzheimer's disease
    • Tsang S.W., Pomakian J., Marshall G.A., Vinters H.V., Cummings J.L., Chen C.P., et al. Disrupted muscarinic M1 receptor signaling correlates with loss of protein kinase C activity and glutamatergic deficit in Alzheimer's disease. Neurobiol Aging 2007, 28:1381-1387.
    • (2007) Neurobiol Aging , vol.28 , pp. 1381-1387
    • Tsang, S.W.1    Pomakian, J.2    Marshall, G.A.3    Vinters, H.V.4    Cummings, J.L.5    Chen, C.P.6
  • 144
    • 41149167170 scopus 로고    scopus 로고
    • Rapid transcriptome characterization for a nonmodel organism using 454 pyrosequencing
    • Vera J.C., Wheat C.W., Fescemyer H.W., Frilander M.J., Crawford D.L., Hanski I., et al. Rapid transcriptome characterization for a nonmodel organism using 454 pyrosequencing. Mol Ecol 2008, 17:1636-1647.
    • (2008) Mol Ecol , vol.17 , pp. 1636-1647
    • Vera, J.C.1    Wheat, C.W.2    Fescemyer, H.W.3    Frilander, M.J.4    Crawford, D.L.5    Hanski, I.6
  • 145
    • 33745268155 scopus 로고    scopus 로고
    • Transcriptional changes in multiple system atrophy and Parkinson's disease putamen
    • Vogt I.R., Lees A.J., Evert B.O., Klockgether T., Bonin M., Wullner U. Transcriptional changes in multiple system atrophy and Parkinson's disease putamen. Exp Neurol 2006, 199:465-478.
    • (2006) Exp Neurol , vol.199 , pp. 465-478
    • Vogt, I.R.1    Lees, A.J.2    Evert, B.O.3    Klockgether, T.4    Bonin, M.5    Wullner, U.6
  • 147
    • 0035477333 scopus 로고    scopus 로고
    • The cell biology of Alzheimer's disease: uncovering the secrets of secretases
    • Walter J., Kaether C., Steiner H., Haass C. The cell biology of Alzheimer's disease: uncovering the secrets of secretases. Curr Opin Neurobiol 2001, 11:585-590.
    • (2001) Curr Opin Neurobiol , vol.11 , pp. 585-590
    • Walter, J.1    Kaether, C.2    Steiner, H.3    Haass, C.4
  • 148
    • 57749195712 scopus 로고    scopus 로고
    • RNA-Seq: a revolutionary tool for transcriptomics
    • Wang Z., Gerstein M., Snyder M. RNA-Seq: a revolutionary tool for transcriptomics. Nat Rev Genet 2009, 10:57-63.
    • (2009) Nat Rev Genet , vol.10 , pp. 57-63
    • Wang, Z.1    Gerstein, M.2    Snyder, M.3
  • 149
    • 43249124363 scopus 로고    scopus 로고
    • Microtubule-associated protein tau in development, degeneration and protection of neurons
    • Wang J.-Z., Liu F. Microtubule-associated protein tau in development, degeneration and protection of neurons. Prog Neurobiol 2008, 85:148-175.
    • (2008) Prog Neurobiol , vol.85 , pp. 148-175
    • Wang, J.-Z.1    Liu, F.2
  • 150
    • 0027258552 scopus 로고
    • Coupling of muscarinic receptors to GTP proteins in postmortem human brain - alterations in Alzheimer's disease
    • Warpman U., Alafuzoff I., Nordberg A. Coupling of muscarinic receptors to GTP proteins in postmortem human brain - alterations in Alzheimer's disease. Neurosci Lett 1993, 150:39-43.
    • (1993) Neurosci Lett , vol.150 , pp. 39-43
    • Warpman, U.1    Alafuzoff, I.2    Nordberg, A.3
  • 151
    • 0041911085 scopus 로고    scopus 로고
    • Synaptic vesicle transport and synaptic membrane transporter sites in excitatory amino acid nerve terminals in Alzheimer disease
    • Westphalen R.I., Scott H.L., Dodd P.R. Synaptic vesicle transport and synaptic membrane transporter sites in excitatory amino acid nerve terminals in Alzheimer disease. J Neural Transm 2003, 110:1013-1027.
    • (2003) J Neural Transm , vol.110 , pp. 1013-1027
    • Westphalen, R.I.1    Scott, H.L.2    Dodd, P.R.3
  • 152
    • 0019410162 scopus 로고
    • Alzheimer disease: evidence for selective loss of cholinergic neurons in the nucleus basalis
    • Whitehouse P.J., Price D.L., Clark A.W., Coyle J.T., DeLong M.R. Alzheimer disease: evidence for selective loss of cholinergic neurons in the nucleus basalis. Ann Neurol 1981, 10:122-126.
    • (1981) Ann Neurol , vol.10 , pp. 122-126
    • Whitehouse, P.J.1    Price, D.L.2    Clark, A.W.3    Coyle, J.T.4    DeLong, M.R.5
  • 153
    • 12244255799 scopus 로고    scopus 로고
    • ABCA1 modulates CSF cholesterol levels and influences the age at onset of Alzheimer's disease
    • Wollmer M.A., Streffer J.R., Lutjohann D., Tsolaki M., Iakovidou V., Hegi T., et al. ABCA1 modulates CSF cholesterol levels and influences the age at onset of Alzheimer's disease. Neurobiol Aging 2003, 24:421-426.
    • (2003) Neurobiol Aging , vol.24 , pp. 421-426
    • Wollmer, M.A.1    Streffer, J.R.2    Lutjohann, D.3    Tsolaki, M.4    Iakovidou, V.5    Hegi, T.6
  • 154
    • 33748660487 scopus 로고    scopus 로고
    • SRp54 (SFRS11), a regulator for tau exon 10 alternative splicing identified by an expression cloning strategy
    • Wu J.Y., Kar A., Kuo D., Yu B., Havlioglu N. SRp54 (SFRS11), a regulator for tau exon 10 alternative splicing identified by an expression cloning strategy. Mol Cell Biol 2006, 26:6739-6747.
    • (2006) Mol Cell Biol , vol.26 , pp. 6739-6747
    • Wu, J.Y.1    Kar, A.2    Kuo, D.3    Yu, B.4    Havlioglu, N.5
  • 155
    • 33748471099 scopus 로고    scopus 로고
    • Inflammation in Alzheimer disease: driving force, bystander or beneficial response?
    • Wyss-Coray T. Inflammation in Alzheimer disease: driving force, bystander or beneficial response?. Nat Med 2006, 12:1005-1015.
    • (2006) Nat Med , vol.12 , pp. 1005-1015
    • Wyss-Coray, T.1
  • 156
    • 0035880474 scopus 로고    scopus 로고
    • Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease
    • Wyttenbach A., Swartz J., Kita H., Thykjaer T., Carmichael J., Bradley J., et al. Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease. Hum Mol Genet 2001, 10:1829-1845.
    • (2001) Hum Mol Genet , vol.10 , pp. 1829-1845
    • Wyttenbach, A.1    Swartz, J.2    Kita, H.3    Thykjaer, T.4    Carmichael, J.5    Bradley, J.6
  • 157
    • 0027321208 scopus 로고
    • Neuron-specific splicing of the Alzheimer amyloid precursor protein gene in a mini-gene system
    • Yamada T., Goto I., Sakaki Y. Neuron-specific splicing of the Alzheimer amyloid precursor protein gene in a mini-gene system. Biochem Biophys Res Commun 1993, 195:442-448.
    • (1993) Biochem Biophys Res Commun , vol.195 , pp. 442-448
    • Yamada, T.1    Goto, I.2    Sakaki, Y.3
  • 158
    • 0037343844 scopus 로고    scopus 로고
    • Defects in expression of genes related to synaptic vesicle trafficking in frontal cortex of Alzheimer's disease
    • Yao P.J., Zhu M., Pyun E.I., Brooks A.I., Therianos S., Meyers V.E., et al. Defects in expression of genes related to synaptic vesicle trafficking in frontal cortex of Alzheimer's disease. Neurobiol Dis 2003, 12:97-109.
    • (2003) Neurobiol Dis , vol.12 , pp. 97-109
    • Yao, P.J.1    Zhu, M.2    Pyun, E.I.3    Brooks, A.I.4    Therianos, S.5    Meyers, V.E.6
  • 159
    • 0028952094 scopus 로고
    • Reduction of AMPA-selective glutamate receptor subunits in the entorhinal cortex of patients with Alzheimer's disease pathology: a biochemical study
    • Yasuda R.P., Ikonomovic M.D., Sheffield R., Rubin R.T., Wolfe B.B., Armstrong D.M. Reduction of AMPA-selective glutamate receptor subunits in the entorhinal cortex of patients with Alzheimer's disease pathology: a biochemical study. Brain Res 1995, 678:161-167.
    • (1995) Brain Res , vol.678 , pp. 161-167
    • Yasuda, R.P.1    Ikonomovic, M.D.2    Sheffield, R.3    Rubin, R.T.4    Wolfe, B.B.5    Armstrong, D.M.6
  • 160
    • 0036770144 scopus 로고    scopus 로고
    • The role of mitogen-activated protein kinase pathways in Alzheimer's disease
    • Zhu X., Lee H.G., Raina A.K., Perry G., Smith M.A. The role of mitogen-activated protein kinase pathways in Alzheimer's disease. Neurosignals 2002, 11:270-281.
    • (2002) Neurosignals , vol.11 , pp. 270-281
    • Zhu, X.1    Lee, H.G.2    Raina, A.K.3    Perry, G.4    Smith, M.A.5


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