Modulation of NF-κB transcription factor activation by Molluscum contagiosum virus proteins

Postepy Higieny i Medycyny Doswiadczalnej

Volumn 68, Issue , 2014, Pages 129-136

  Struzik, Justyna ^a   Szulc Dąbrowska, Lidia ^a   Niemiałtowski, Marek ^a  

^a WARSAW UNIVERSITY OF LIFE SCIENCES   (Poland)

Author keywords

Molluscum contagiosum virus; NF B; Transcription factor

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 18;

ANIMAL; APOPTOSIS; GENETICS; HUMAN; IMMUNOLOGY; IMMUNOMODULATION; METABOLISM; MOLLUSCIPOXVIRUS; PHOSPHORYLATION; PHYSIOLOGY; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANIMALS; APOPTOSIS; HUMANS; IMMUNOMODULATION; INTERFERON-GAMMA; INTERLEUKIN-18; MOLLUSCUM CONTAGIOSUM VIRUS; NF-KAPPA B; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

EID: 84901612328     PISSN: 00325449     EISSN: 17322693     Source Type: Journal    
DOI: 10.5604/17322693.1088053     Document Type: Review

References (46)

1. Alcami A.: Viral mimicry of cytokines, chemokines and their receptors. Nat. Rev. Immunol., 2003; 3: 36-50
2. Barry M., Wasilenko S.T., Stewart T.L., Taylor J.M.: Apoptosis regulator genes encoded by poxviruses. Prog. Mol. Subcell. Biol., 2004; 36: 19-37
3. Bugert J.J., Melquiot N., Kehm R.: Molluscum contagiosum virus expresses late genes in primary human fibroblasts but does not produce infectious progeny. Virus Genes, 2001; 22: 27-33
4. Buller R.M., Palumbo G.J.: Poxvirus pathogenesis. Microbiol. Rev., 1991; 55: 80-122
5. Challa S., Woelfel M., Guildford M., Moquin D., Chan F.K.: Viral cell death inhibitor MC159 enhances innate immunity against vaccinia virus infection. J. Virol., 2010; 84: 10467-10476
6. Dhar S., Jain S., Verma G., Tanwar R.K.: Disseminated and atypical molluscum contagiosum in an AIDS patient. Indian J. Dermatol. Venerol. Leprol., 1996; 62: 331-332
7. Esteban D.J., Buller R.M.: Ectromelia virus: the causative agent of mousepox. J. Gen. Virol., 2005; 86: 2645-2659
8. Fox R., Thiemann A., Everest D., Steinbach F., Dastjerdi A., Finnegan C.: Molluscum contagiosum in two donkeys. Vet. Rec., 2012; 170: 649
9. Gil J., Bermejo M., Alcamí J.: HIV and apoptosis: a complex interaction between cell death and virus survival. Prog. Mol. Subcell. Biol., 2004; 36: 117-149
10. Gil J., Rullas J., Alcamí J., Esteban M.: MC159L protein from poxvirus molluscum contagiosum virus inhibits NF-κB activation and apoptosis induced by PKR. J. Gen. Virol., 2001; 82: 3027-3034
11. Gould D.: An overview of molluscum contagiosum: a viral skin condition. Nurs. Stand., 2008; 22: 45-48
12. Hayden M.S., Ghosh S.: Shared principles in NF-κB signaling. Cell, 2008; 132: 344-362
13. Hiscott J., Kwon H., Génin P.: Hostile takeovers: viral appropriation of the NF-κB pathway. J. Clin. Invest., 2001; 107: 143-151
14. Kojima H., Aizawa Y., Yanai Y., Nagaoka K., Takeuchi M., Ohta T., Ikegami H., Ikeda M., Kurimoto M.: An essential role for NF-κB in IL-18-induced IFN-γ expression in KG-1 cells. J. Immunol., 1999; 162: 5063-5069
15. Krammer P.H.: CD95 (APO-1/Fas)-mediated apoptosis: live and let die. Adv. Immunol., 1999; 71: 163-210
16. Lee R., Schwartz R.A.: Pediatric molluscum contagiosum: reflections on the last challenging poxvirus infection, Part 1. Cutis, 2010; 86: 230-236
17. Li F.Y., Jeffrey P.D., Yu J.W., Shi Y.: Crystal structure of a viral FLIP: insights into FLIP-mediated inhibition of death receptor signaling. J. Biol. Chem., 2006; 281: 2960-2968
18. Li Y., Meyer H., Zhao H., Damon I.K.: GC content-based panpox universal PCR assays for poxvirus detection. J. Clin. Microbiol., 2010; 48: 268-276
19. Luke J.D., Silverberg N.B.: Vertically transmitted molluscum contagiosum infection. Pediatrics, 2010; 125: e423-e425
20. Markum E., Baillie J.: Combination of essential oil of Melaleuca alternifolia and iodine in the treatment of molluscum contagiosum in children. J. Drugs Dermatol., 2012; 11: 349-354
21. Mohamed M.R., McFadden G.: NFκB inhibitors: strategies from poxviruses. Cell Cycle, 2009; 8: 3125-3132
22. Molluscum contagiosum. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001829/(12.04.2013)
23. Moss B., Shisler J.L., Xiang Y., Senkevich T.G.: Immune-defense molecules of molluscum contagiosum virus, a human poxvirus. Trends Microbiol., 2000; 8: 473-477
24. Murao L.E., Shisler J.L.: The MCV MC159 protein inhibits late, but not early, events of TNF-α-i induced NF-κB activation. Virology, 2005; 340: 255-264
25. Nakanishi K., Yoshimoto T., Tsutsui H., Okamura H.: Interleukin- 18 regulates both Th1 and Th2 responses. Annu. Rev. Immunol., 2001; 19: 423-474
26. Nichols D.B., Shisler J.L.: Poxvirus MC160 protein utilizes multiple mechanisms to inhibit NF-κB activation mediated via components of the tumor necrosis factor receptor 1 signal transduction pathway. J. Virol., 2009; 83: 3162-3174
27. Nichols D.B., Shisler J.L.: The MC160 protein expressed by the dermatotropic poxvirus molluscum contagiosum virus prevents tumor necrosis factor α-induced NF-κB activation via inhibition of Iκ kinase complex formation. J. Virol., 2006; 80: 578-586
28. Oztürk S., Schleich K., Lavrik I.N.: Cellular FLICE-like inhibitory proteins (c-FLIPs): fine-tuners of life and death decisions. Exp. Cell Res., 2012; 318: 1324-1331
29. Park H.H., Lo Y.C., Lin S.C., Wang L., Yang J.K., Wu H.: The death domain superfamily in intracellular signaling of apoptosis and inflammation. Annu. Rev. Immunol., 2007; 25: 561-586
30. Perkins N.D.: The Rel/NF-κB family: friend and foe. Trends Biochem. Sci., 2000; 25: 434-440
31. Postlethwaite R.: Molluscum contagiosum. Arch. Environ. Health, 1970; 21: 432-452
32. Randall C.M., Jokela J.A., Shisler J.L.: The MC159 protein from the molluscum contagiosum poxvirus inhibits NF-κB activation by interacting with the IκB kinase complex. J. Immunol., 2012; 188: 2371-2379
33. Seet B.T., Johnston J.B., Brunetti C.R., Barrett J.W., Everett H., Cameron C., Sypula J., Nazarian S.H., Lucas A., McFadden G.: Poxviruses and immune evasion. Annu. Rev. Immunol., 2003; 21: 377-423
34. Sen S., Goswami B.K., Karjyi N., Bhaumik P.: Disfiguring molluscum contagiosum in a HIV-positive patient responding to antiretroviral therapy. Indian J. Dermatol., 2009; 54: 180-182
35. Senkevich T.G., Bugert J.J., Sisler J.R., Koonin E.V., Darai G., Moss B.: Genome sequence of a human tumorigenic poxvirus: prediction of specific host response-evasion genes. Science, 1996; 273: 813-816
36. Smith V.P., Bryant N.A., Alcamí A.: Ectromelia, vaccinia and cowpox viruses encode secreted interleukin-18-binding proteins. J. Gen. Virol., 2000; 81: 1223-1230
37. Steinberg A.D.: Recent worldwide research on animal pox viruses. Open Source Center, MITRE Corp., January 2008; p.24
38. Thome M., Schneider P., Hofmann K., Fickenscher H., Meinl E., Neipel F., Mattmann C., Burns K., Bodmer J.L., Schröter M., Scaffidi C., Krammer P.H., Peter M.E., Tschopp J.: Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors. Nature, 1997; 386: 517-521
39. van der Wouden J.C., van der Sande R., van Suijlekom-Smit L.W., Berger M., Butler C.C., Koning S.: Interventions for cutaneous molluscum contagiosum. Cochrane Database Syst. Rev., 2009; 7: CD004767
40. Virus Taxonomy: 2012 Release. http://www.ictvonline.org/virusTaxonomy.asp?taxnode-id=20120371 (12.04.2013)
41. Wan F., Lenardo M.J.: Specification of DNA binding activity of NF-κB proteins. Cold Spring Harb. Perspect. Biol., 2009; 1: a000067
42. Xiang Y., Moss B.: Correspondence of the functional epitopes of poxvirus and human interleukin-18-binding proteins. J. Virol., 2001; 75: 9947-9954
43. Xiang Y., Moss B.: Identification of human and mouse homologs of the MC51L-53L-54L family of secreted glycoproteins encoded by the Molluscum contagiosum poxvirus. Virology, 1999; 257: 297-302
44. Xiang Y., Moss B.: IL-18 binding and inhibition of interferon γ induction by human poxvirus-encoded proteins. Proc. Natl. Acad. Sci. USA, 1999; 96: 11537-11542
45. Xiang Y., Moss B.: Molluscum contagiosum virus interleukin-18 (IL-18) binding protein is secreted as a full-length form that binds cell surface glycosaminoglycans through the C-terminal tail and a furin-cleaved form with only the IL-18 binding domain. J. Virol., 2003; 77: 2623-2630
46. Yang J.K., Wang L., Zheng L., Wan F., Ahmed M., Lenardo M.J., Wu H.: Crystal structure of MC159 reveals molecular mechanism of DISC assembly and FLIP inhibition. Mol. Cell, 2005; 20: 939-949