A novel Ku70 function in colorectal homeostasis separate from nonhomologous end joining

Oncogene

Volumn 33, Issue 21, 2014, Pages 2748-2757

  Puebla Osorio, N ^a   Kim, J ^a   Ojeda, S ^a   Zhang, H ^a   Tavana, O ^a,b   Li, S ^a   Wang, Y ^a   Ma, Q ^a,b   Schluns, K S ^a,b   Zhu, C ^a,b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

beta catenin; colorectal cancer; Ku70; Nonhomologous end joining; senescence; Wnt signaling

Indexed keywords

CYCLIN D1; KU ANTIGEN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE 4; PROTEIN P53; UNCLASSIFIED DRUG;

ADENOMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL PROLIFERATION; COLON CARCINOGENESIS; COLON MUCOSA; CONTROLLED STUDY; DIABETES MELLITUS; DNA END JOINING REPAIR; GENE MUTATION; HOMEOSTASIS; IN VIVO STUDY; INFLAMMATION; MOUSE; NONHUMAN; ONCOGENE C MYC; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY;

MUS;

ADENOCARCINOMA; ANIMALS; ANTIGENS, NUCLEAR; CARCINOGENESIS; CELL AGING; CELL PROLIFERATION; CELLS, CULTURED; COLON; COLORECTAL NEOPLASMS; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; DNA END-JOINING REPAIR; DNA-BINDING PROTEINS; EPITHELIAL CELLS; HOMEOSTASIS; HUMANS; INTERLEUKIN-6; MICE; MICE, KNOCKOUT; PROTO-ONCOGENE PROTEINS C-MYC; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEIN P53; WNT SIGNALING PATHWAY;

EID: 84901496121     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.234     Document Type: Article

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