-
1
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
-
Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang SI, et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 1997;275:1943-7.
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
Podsypanina, K.4
Bose, S.5
Wang, S.I.6
-
2
-
-
0030837555
-
PTEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
-
Myers MP, Stolarov JP, Eng C, Li J, Wang SI, Wigler MH, et al. PTEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc Natl Acad Sci U S A 1997; 94:9052-7.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 9052-9057
-
-
Myers, M.P.1
Stolarov, J.P.2
Eng, C.3
Li, J.4
Wang, S.I.5
Wigler, M.H.6
-
3
-
-
17144436629
-
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
Steck PA, Pershouse MA, Jasser SA, Yung WK, Lin H, Ligon AH, et al. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet 1997;15:356-62.
-
(1997)
Nat Genet
, vol.15
, pp. 356-362
-
-
Steck, P.A.1
Pershouse, M.A.2
Jasser, S.A.3
Yung, W.K.4
Lin, H.5
Ligon, A.H.6
-
4
-
-
0033579163
-
Mutational spectra of PTEN/MMAC1gene: A tumor suppressor with lipid phosphatase activity
-
Ali IU, Schriml LM, Dean M. Mutational spectra of PTEN/MMAC1gene: a tumor suppressor with lipid phosphatase activity. J Natl Cancer Inst 1999;91:1922-32.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1922-1932
-
-
Ali, I.U.1
Schriml, L.M.2
Dean, M.3
-
5
-
-
0035949707
-
Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression
-
Kwabi-Addo B, Giri D, Schmidt K, Podsypanina K, Parsons R, Greenberg N, et al. Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression. Proc Natl Acad Sci U S A 2001;98:11563-8.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 11563-11568
-
-
Kwabi-Addo, B.1
Giri, D.2
Schmidt, K.3
Podsypanina, K.4
Parsons, R.5
Greenberg, N.6
-
6
-
-
0031922369
-
Homozygous deletion of the PTEN tumor suppressor gene in a subset of prostate adenocarcinomas
-
Wang SI, Parsons R, Ittmann M. Homozygous deletion of the PTEN tumor suppressor gene in a subset of prostate adenocarcinomas. Clin Cancer Res 1998;4:811-5.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 811-815
-
-
Wang, S.I.1
Parsons, R.2
Ittmann, M.3
-
7
-
-
0032506011
-
The lipid phosphatase activity of PTEN is critical for its tumor supressor function
-
Myers MP, Pass I, Batty IH, Van der Kaay J, Stolarov JP, Hemmings BA, et al. The lipid phosphatase activity of PTEN is critical for its tumor supressor function. Proc Natl Acad Sci U S A 1998;95:13513-8.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 13513-13518
-
-
Myers, M.P.1
Pass, I.2
Batty, I.H.3
Van Der Kaay, J.4
Stolarov, J.P.5
Hemmings, B.A.6
-
8
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
-
Maehama T, Dixon JE. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 1998;273:13375-8.
-
(1998)
J Biol Chem
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
9
-
-
79957926724
-
WWP2 is an E3 ubiquitin ligase for PTEN
-
Maddika S, Kavela S, Rani N, Palicharla VR, Pokorny JL, Sarkaria JN, et al. WWP2 is an E3 ubiquitin ligase for PTEN. Nat Cell Biol 2011;13:730-5.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 730-735
-
-
Maddika, S.1
Kavela, S.2
Rani, N.3
Palicharla, V.R.4
Pokorny, J.L.5
Sarkaria, J.N.6
-
10
-
-
0032512720
-
Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit
-
Allen PB, Kwon YG, Nairn AC, Greengard P. Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit. J Biol Chem 1998;273:4089-95.
-
(1998)
J Biol Chem
, vol.273
, pp. 4089-4095
-
-
Allen, P.B.1
Kwon, Y.G.2
Nairn, A.C.3
Greengard, P.4
-
11
-
-
0037515628
-
PNUTS, a protein phosphatase 1 (PP1) nuclear targeting subunit. Characterization of its PP1- And RNA-binding domains and regulation by phosphorylation
-
Kim YM, Watanabe T, Allen PB, Kim YM, Lee SJ, Greengard P, et al. PNUTS, a protein phosphatase 1 (PP1) nuclear targeting subunit. Characterization of its PP1- and RNA-binding domains and regulation by phosphorylation. J Biol Chem 2003;278:13819-28.
-
(2003)
J Biol Chem
, vol.278
, pp. 13819-13828
-
-
Kim, Y.M.1
Watanabe, T.2
Allen, P.B.3
Kim, Y.M.4
Lee, S.J.5
Greengard, P.6
-
12
-
-
46749090395
-
Downregulation of the phosphatase nuclear targeting subunit (PNUTS) triggers pRB dephosphorylation and apoptosis in pRB positive tumor cell lines
-
Grana X. Downregulation of the phosphatase nuclear targeting subunit (PNUTS) triggers pRB dephosphorylation and apoptosis in pRB positive tumor cell lines. Cancer Biol Ther 2008;7:842-4.
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 842-844
-
-
Grana, X.1
-
13
-
-
0036389746
-
PNUTS (phosphatase nuclear targeting subunit) inhibits retinoblastoma-directed PP1 activity
-
Udho E, Tedesco VC, Zygmunt A, Krucher NA. PNUTS (phosphatase nuclear targeting subunit) inhibits retinoblastoma-directed PP1 activity. Biochem Biophys Res Commun 2002;297:463-7.
-
(2002)
Biochem Biophys Res Commun
, vol.297
, pp. 463-467
-
-
Udho, E.1
Tedesco, V.C.2
Zygmunt, A.3
Krucher, N.A.4
-
14
-
-
33845977965
-
Ubiquitination regulates PTEN nuclear import and tumor suppression
-
Trotman LC, Wang X, Alimonti A, Chen Z, Teruya-Feldstein J, Yang H, et al. Ubiquitination regulates PTEN nuclear import and tumor suppression. Cell 2007;128:141-56.
-
(2007)
Cell
, vol.128
, pp. 141-156
-
-
Trotman, L.C.1
Wang, X.2
Alimonti, A.3
Chen, Z.4
Teruya-Feldstein, J.5
Yang, H.6
-
15
-
-
53649106156
-
The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network
-
Song MS, Salmena L, Carracedo A, Egia A, Lo-Coco F, Teruya-Feldstein J, et al. The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network. Nature 2008;455:813-7.
-
(2008)
Nature
, vol.455
, pp. 813-817
-
-
Song, M.S.1
Salmena, L.2
Carracedo, A.3
Egia, A.4
Lo-Coco, F.5
Teruya-Feldstein, J.6
-
17
-
-
22044450542
-
Array-based comparative genomic hybridization identifies localized DNA amplifications and homozygous deletions in pancreatic cancer
-
Bashyam MD, Bair R, Kim YH, Wang P, Hernandez-Boussard T, Karikari CA, et al. Array-based comparative genomic hybridization identifies localized DNA amplifications and homozygous deletions in pancreatic cancer. Neoplasia 2005;7:556-62.
-
(2005)
Neoplasia
, vol.7
, pp. 556-562
-
-
Bashyam, M.D.1
Bair, R.2
Kim, Y.H.3
Wang, P.4
Hernandez-Boussard, T.5
Karikari, C.A.6
-
18
-
-
63849329936
-
Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells
-
Marty B, Maire V, Gravier E, Rigaill G, Vincent-Salomon A, Kappler M, et al. Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells. Breast Cancer Res 2008;10:R101.
-
(2008)
Breast Cancer Res
, vol.10
-
-
Marty, B.1
Maire, V.2
Gravier, E.3
Rigaill, G.4
Vincent-Salomon, A.5
Kappler, M.6
-
19
-
-
34250687198
-
Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity
-
Saal LH, Johansson P, Holm K, Gruvberger-Saal SK, She QB, Maurer M, et al. Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity. Proc Natl Acad Sci U S A 2007;104:7564-9.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 7564-7569
-
-
Saal, L.H.1
Johansson, P.2
Holm, K.3
Gruvberger-Saal, S.K.4
She, Q.B.5
Maurer, M.6
-
20
-
-
0032475861
-
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
-
Stambolic V, Suzuki A, de la Pompa JL, Brothers GM, Mirtsos C, Sasaki T, et al. Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell 1998;95:29-39.
-
(1998)
Cell
, vol.95
, pp. 29-39
-
-
Stambolic, V.1
Suzuki, A.2
De La Pompa, J.L.3
Brothers, G.M.4
Mirtsos, C.5
Sasaki, T.6
-
21
-
-
0035873953
-
Tumor suppressor and anti-inflammatory actions of PPARgamma agonists are mediated via upregulation of PTEN
-
Patel L, Pass I, Coxon P, Downes CP, Smith SA, Macphee CH. Tumor suppressor and anti-inflammatory actions of PPARgamma agonists are mediated via upregulation of PTEN. Curr Biol 2001;11:764-8.
-
(2001)
Curr Biol
, vol.11
, pp. 764-768
-
-
Patel, L.1
Pass, I.2
Coxon, P.3
Downes, C.P.4
Smith, S.A.5
Macphee, C.H.6
-
22
-
-
0034854091
-
Regulation of PTEN transcription by p53
-
Stambolic V, MacPherson D, Sas D, Lin Y, Snow B, Jang Y, et al. Regulation of PTEN transcription by p53. Mol Cell 2001;8:317-25.
-
(2001)
Mol Cell
, vol.8
, pp. 317-325
-
-
Stambolic, V.1
MacPherson, D.2
Sas, D.3
Lin, Y.4
Snow, B.5
Jang, Y.6
-
23
-
-
0035199914
-
The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling
-
Virolle T, Adamson ED, Baron V, Birle D, Mercola D, Mustelin T, et al. The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling. Nat Cell Biol 2001;3:1124-8.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 1124-1128
-
-
Virolle, T.1
Adamson, E.D.2
Baron, V.3
Birle, D.4
Mercola, D.5
Mustelin, T.6
-
24
-
-
51849155581
-
Post-translational regulation of PTEN
-
Wang X, Jiang X. Post-translational regulation of PTEN. Oncogene 2008;27:5454-63.
-
(2008)
Oncogene
, vol.27
, pp. 5454-5463
-
-
Wang, X.1
Jiang, X.2
-
25
-
-
38349030742
-
New insights into PTEN
-
Tamguney T, Stokoe D. New insights into PTEN. J Cell Sci 2007;120:4071-9.
-
(2007)
J Cell Sci
, vol.120
, pp. 4071-4079
-
-
Tamguney, T.1
Stokoe, D.2
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