-
1
-
-
33745614062
-
Stem cells, ageing and the quest for immortality
-
CrossRefPubMed
-
Rando, T.A. (2006) Stem cells, ageing and the quest for immortality. Nature 441, 1080-1086 CrossRef PubMed
-
(2006)
Nature
, vol.441
, pp. 1080-1086
-
-
Rando, T.A.1
-
2
-
-
84878864199
-
The hallmarks of aging
-
CrossRefPubMed
-
Lopez-Otin, C., Blasco, M.A., Partridge, L., Serrano, M. and Kroemer, G. (2013) The hallmarks of aging. Cell 153, 1194-1217 CrossRef PubMed
-
(2013)
Cell
, vol.153
, pp. 1194-1217
-
-
Lopez-Otin, C.1
Blasco, M.A.2
Partridge, L.3
Serrano, M.4
Kroemer, G.5
-
3
-
-
13944270339
-
Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
-
CrossRefPubMed
-
Campisi, J. (2005) Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 120, 513-522 CrossRef PubMed
-
(2005)
Cell
, vol.120
, pp. 513-522
-
-
Campisi, J.1
-
4
-
-
79955513612
-
Manifestations and mechanisms of stem cell aging
-
CrossRefPubMed
-
Liu, L. and Rando, T.A. (2011) Manifestations and mechanisms of stem cell aging. J. Cell Biol. 193, 257-266 CrossRef PubMed
-
(2011)
J. Cell Biol.
, vol.193
, pp. 257-266
-
-
Liu, L.1
Rando, T.A.2
-
5
-
-
34250007142
-
Deficiencies in dna damage repair limit the function of haematopoietic stem cells with age
-
CrossRefPubMed
-
Rossi, D.J., Bryder, D., Seita, J., Nussenzweig, A., Hoeijmakers, J. and Weissman, I.L. (2007) Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature 447, 725-729 CrossRef PubMed
-
(2007)
Nature
, vol.447
, pp. 725-729
-
-
Rossi, D.J.1
Bryder, D.2
Seita, J.3
Nussenzweig, A.4
Hoeijmakers, J.5
Weissman, I.L.6
-
6
-
-
84870488608
-
Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of dna methyltransferase 1
-
CrossRefPubMed
-
Li, J., Jiang, T.X., Hughes, M.W., Wu, P., Yu, J., Widelitz, R.B., Fan, G. and Chuong, C.M. (2012) Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1. J. Invest. Dermatol. 132, 2681-2690 CrossRef PubMed
-
(2012)
J. Invest. Dermatol.
, vol.132
, pp. 2681-2690
-
-
Li, J.1
Jiang, T.X.2
Hughes, M.W.3
Wu, P.4
Yu, J.5
Widelitz, R.B.6
Fan, G.7
Chuong, C.M.8
-
7
-
-
84892440367
-
Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging
-
CrossRefPubMed
-
Liu, L., Cheung, T.H., Charville, G.W., Hurgo, B.M., Leavitt, T., Shih, J., Brunet, A. and Rando, T.A. (2013) Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging. Cell Rep. 4, 189-204 CrossRef PubMed
-
(2013)
Cell Rep.
, vol.4
, pp. 189-204
-
-
Liu, L.1
Cheung, T.H.2
Charville, G.W.3
Hurgo, B.M.4
Leavitt, T.5
Shih, J.6
Brunet, A.7
Rando, T.A.8
-
8
-
-
0037421896
-
Telomere dysfunction and atm deficiency compromises organ homeostasis and accelerates ageing
-
CrossRefPubMed
-
Wong, K.K., Maser, R.S., Bachoo, R.M., Menon, J., Carrasco, D.R., Gu, Y., Alt, F.W. and DePinho, R.A. (2003) Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing. Nature 421, 643-648 CrossRef PubMed
-
(2003)
Nature
, vol.421
, pp. 643-648
-
-
Wong, K.K.1
Maser, R.S.2
Bachoo, R.M.3
Menon, J.4
Carrasco, D.R.5
Gu, Y.6
Alt, F.W.7
DePinho, R.A.8
-
9
-
-
40349085766
-
The longest telomeres: A general signature of adult stem cell compartments
-
CrossRefPubMed
-
Flores, I., Canela, A., Vera, E., Tejera, A., Cotsarelis, G. and Blasco, M.A. (2008) The longest telomeres: a general signature of adult stem cell compartments. Genes Dev. 22, 654-667 CrossRef PubMed
-
(2008)
Genes Dev.
, vol.22
, pp. 654-667
-
-
Flores, I.1
Canela, A.2
Vera, E.3
Tejera, A.4
Cotsarelis, G.5
Blasco, M.A.6
-
10
-
-
33749171885
-
Increasing p16ink4a expression decreases forebrain progenitors and neurogenesis during ageing
-
CrossRefPubMed
-
Molofsky, A.V., Slutsky, S.G., Joseph, N.M., He, S., Pardal, R., Krishnamurthy, J., Sharpless, N.E. and Morrison, S.J. (2006) Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing. Nature 443, 448-452 CrossRef PubMed
-
(2006)
Nature
, vol.443
, pp. 448-452
-
-
Molofsky, A.V.1
Slutsky, S.G.2
Joseph, N.M.3
He, S.4
Pardal, R.5
Krishnamurthy, J.6
Sharpless, N.E.7
Morrison, S.J.8
-
11
-
-
0029863342
-
Neurogenesis in the dentate gyrus of the adult rat: Age-related decrease of neuronal progenitor proliferation
-
PubMed
-
Kuhn, H.G., Dickinson-Anson, H. and Gage, F.H. (1996) Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J. Neurosci. 16, 2027-2033 PubMed
-
(1996)
J. Neurosci.
, vol.16
, pp. 2027-2033
-
-
Kuhn, H.G.1
Dickinson-Anson, H.2
Gage, F.H.3
-
12
-
-
77955368742
-
Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging
-
CrossRefPubMed
-
Lugert, S., Basak, O., Knuckles, P., Haussler, U., Fabel, K., Gotz, M., Haas, C.A., Kempermann, G., Taylor, V. and Giachino, C. (2010) Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging. Cell Stem Cell 6, 445-456 CrossRef PubMed
-
(2010)
Cell Stem Cell
, vol.6
, pp. 445-456
-
-
Lugert, S.1
Basak, O.2
Knuckles, P.3
Haussler, U.4
Fabel, K.5
Gotz, M.6
Haas, C.A.7
Kempermann, G.8
Taylor, V.9
Giachino, C.10
-
13
-
-
80052410357
-
The ageing systemic milieu negatively regulates neurogenesis and cognitive function
-
CrossRefPubMed
-
Villeda, S.A., Luo, J., Mosher, K.I., Zou, B., Britschgi, M., Bieri, G., Stan, T.M., Fainberg, N., Ding, Z., Eggel, A. et al. (2011) The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature 477, 90-94 CrossRef PubMed
-
(2011)
Nature
, vol.477
, pp. 90-94
-
-
Villeda, S.A.1
Luo, J.2
Mosher, K.I.3
Zou, B.4
Britschgi, M.5
Bieri, G.6
Stan, T.M.7
Fainberg, N.8
Ding, Z.9
Eggel, A.10
-
14
-
-
70350506802
-
Foxo3 regulates neural stem cell homeostasis
-
CrossRefPubMed
-
Renault, V.M., Rafalski, V.A., Morgan, A.A., Salih, D.A., Brett, J.O., Webb, A.E., Villeda, S.A., Thekkat, P.U., Guillerey, C., Denko, N.C. et al. (2009) FoxO3 regulates neural stem cell homeostasis. Cell Stem Cell 5, 527-539 CrossRef PubMed
-
(2009)
Cell Stem Cell
, vol.5
, pp. 527-539
-
-
Renault, V.M.1
Rafalski, V.A.2
Morgan, A.A.3
Salih, D.A.4
Brett, J.O.5
Webb, A.E.6
Villeda, S.A.7
Thekkat, P.U.8
Guillerey, C.9
Denko, N.C.10
-
15
-
-
79955688967
-
Division-coupled astrocytic differentiation and age-related depletion of neural stem cells in the adult hippocampus
-
CrossRefPubMed
-
Encinas, J.M., Michurina, T.V., Peunova, N., Park, J.H., Tordo, J., Peterson, D.A., Fishell, G., Koulakov, A. and Enikolopov, G. (2011) Division-coupled astrocytic differentiation and age-related depletion of neural stem cells in the adult hippocampus. Cell Stem Cell 8, 566-579 CrossRef PubMed
-
(2011)
Cell Stem Cell
, vol.8
, pp. 566-579
-
-
Encinas, J.M.1
Michurina, T.V.2
Peunova, N.3
Park, J.H.4
Tordo, J.5
Peterson, D.A.6
Fishell, G.7
Koulakov, A.8
Enikolopov, G.9
-
16
-
-
77958187285
-
Intestinal stem cells
-
CrossRefPubMed
-
Umar, S. (2010) Intestinal stem cells. Curr. Gastroenterol. Rep. 12, 340-348 CrossRef PubMed
-
(2010)
Curr. Gastroenterol. Rep.
, vol.12
, pp. 340-348
-
-
Umar, S.1
-
17
-
-
84862946094
-
The intestinal stem cell markers bmi1 and lgr5 identify two functionally distinct populations
-
CrossRefPubMed
-
Yan, K.S., Chia, L.A., Li, X., Ootani, A., Su, J., Lee, J.Y., Su, N., Luo, Y., Heilshorn, S.C., Amieva, M.R. et al. (2012) The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations. Proc. Natl. Acad. Sci. U.S.A. 109, 466-471 CrossRef PubMed
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 466-471
-
-
Yan, K.S.1
Chia, L.A.2
Li, X.3
Ootani, A.4
Su, J.5
Lee, J.Y.6
Su, N.7
Luo, Y.8
Heilshorn, S.C.9
Amieva, M.R.10
-
18
-
-
0012872309
-
Identification of a putative intestinal stem cell and early lineage marker; musashi-1
-
CrossRefPubMed
-
Potten, C.S., Booth, C., Tudor, G.L., Booth, D., Brady, G., Hurley, P., Ashton, G., Clarke, R., Sakakibara, S. and Okano, H. (2003) Identification of a putative intestinal stem cell and early lineage marker; musashi-1. Differentiation 71, 28-41 CrossRef PubMed
-
(2003)
Differentiation
, vol.71
, pp. 28-41
-
-
Potten, C.S.1
Booth, C.2
Tudor, G.L.3
Booth, D.4
Brady, G.5
Hurley, P.6
Ashton, G.7
Clarke, R.8
Sakakibara, S.9
Okano, H.10
-
19
-
-
46249128798
-
Bmi1 is expressed in vivo in intestinal stem cells
-
CrossRefPubMed
-
Sangiorgi, E. and Capecchi, M.R. (2008) Bmi1 is expressed in vivo in intestinal stem cells. Nat. Genet. 40, 915-920 CrossRef PubMed
-
(2008)
Nat. Genet.
, vol.40
, pp. 915-920
-
-
Sangiorgi, E.1
Capecchi, M.R.2
-
20
-
-
80054041585
-
A reserve stem cell population in small intestine renders lgr5-positive cells dispensable
-
CrossRefPubMed
-
Tian, H., Biehs, B., Warming, S., Leong, K.G., Rangell, L., Klein, O.D. and de Sauvage, F.J. (2011) A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable. Nature 478, 255-259 CrossRef PubMed
-
(2011)
Nature
, vol.478
, pp. 255-259
-
-
Tian, H.1
Biehs, B.2
Warming, S.3
Leong, K.G.4
Rangell, L.5
Klein, O.D.6
De Sauvage, F.J.7
-
21
-
-
35548974423
-
Identification of stem cells in small intestine and colon by marker gene lgr5
-
CrossRefPubMed
-
Barker, N., van Es, J.H., Kuipers, J., Kujala, P., van den Born, M., Cozijnsen, M., Haegebarth, A., Korving, J., Begthel, H., Peters, P.J. et al. (2007) Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 449, 1003-1007 CrossRef PubMed
-
(2007)
Nature
, vol.449
, pp. 1003-1007
-
-
Barker, N.1
Van Es, J.H.2
Kuipers, J.3
Kujala, P.4
Van Den Born, M.5
Cozijnsen, M.6
Haegebarth, A.7
Korving, J.8
Begthel, H.9
Peters, P.J.10
-
22
-
-
0032526476
-
Age changes in stem cells of murine small intestinal crypts
-
CrossRefPubMed
-
Martin, K., Kirkwood, T.B. and Potten, C.S. (1998) Age changes in stem cells of murine small intestinal crypts. Exp. Cell Res. 241, 316-323 CrossRef PubMed
-
(1998)
Exp. Cell Res.
, vol.241
, pp. 316-323
-
-
Martin, K.1
Kirkwood, T.B.2
Potten, C.S.3
-
23
-
-
0033929329
-
Age-related changes in irradiation-induced apoptosis and expression of p21 and p53 in crypt stem cells of murine intestine
-
CrossRefPubMed
-
Martin, K., Potten, C.S. and Kirkwood, T.B. (2000) Age-related changes in irradiation-induced apoptosis and expression of p21 and p53 in crypt stem cells of murine intestine. Ann. N.Y. Acad. Sci. 908, 315-318 CrossRef PubMed
-
(2000)
Ann. N.Y. Acad. Sci.
, vol.908
, pp. 315-318
-
-
Martin, K.1
Potten, C.S.2
Kirkwood, T.B.3
-
24
-
-
0020617574
-
Age-related differences in absolute numbers of skeletal muscle satellite cells
-
CrossRefPubMed
-
Gibson, M.C. and Schultz, E. (1983) Age-related differences in absolute numbers of skeletal muscle satellite cells. Muscle Nerve 6, 574-580 CrossRef PubMed
-
(1983)
Muscle Nerve
, vol.6
, pp. 574-580
-
-
Gibson, M.C.1
Schultz, E.2
-
25
-
-
0344827208
-
Notch-mediated restoration of regenerative potential to aged muscle
-
CrossRefPubMed
-
Conboy, I.M., Conboy, M.J., Smythe, G.M. and Rando, T.A. (2003) Notch-mediated restoration of regenerative potential to aged muscle. Science 302, 1575-1577 CrossRef PubMed
-
(2003)
Science
, vol.302
, pp. 1575-1577
-
-
Conboy, I.M.1
Conboy, M.J.2
Smythe, G.M.3
Rando, T.A.4
-
26
-
-
33646264523
-
Satellite-cell pool size does matter: Defining the myogenic potency of aging skeletal muscle
-
CrossRefPubMed
-
Shefer, G., Van de Mark, D.P., Richardson, J.B. and Yablonka-Reuveni, Z. (2006) Satellite-cell pool size does matter: defining the myogenic potency of aging skeletal muscle. Dev. Biol. 294, 50-66 CrossRef PubMed
-
(2006)
Dev. Biol.
, vol.294
, pp. 50-66
-
-
Shefer, G.1
Van De Mark, D.P.2
Richardson, J.B.3
Yablonka-Reuveni, Z.4
-
27
-
-
0037204538
-
Activation of an adipogenic program in adult myoblasts with age
-
CrossRefPubMed
-
Taylor-Jones, J.M., McGehee, R.E., Rando, T.A., Lecka-Czernik, B., Lipschitz, D.A. and Peterson, C.A. (2002) Activation of an adipogenic program in adult myoblasts with age. Mech. Ageing Dev. 123, 649-661 CrossRef PubMed
-
(2002)
Mech. Ageing Dev.
, vol.123
, pp. 649-661
-
-
Taylor-Jones, J.M.1
McGehee, R.E.2
Rando, T.A.3
Lecka-Czernik, B.4
Lipschitz, D.A.5
Peterson, C.A.6
-
28
-
-
34547924424
-
Increased wnt signaling during aging alters muscle stem cell fate and increases fibrosis
-
CrossRefPubMed
-
Brack, A.S., Conboy, M.J., Roy, S., Lee, M., Kuo, C.J., Keller, C. and Rando, T.A. (2007) Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis. Science 317, 807-810 CrossRef PubMed
-
(2007)
Science
, vol.317
, pp. 807-810
-
-
Brack, A.S.1
Conboy, M.J.2
Roy, S.3
Lee, M.4
Kuo, C.J.5
Keller, C.6
Rando, T.A.7
-
29
-
-
84894232184
-
Geriatric muscle stem cells switch reversible quiescence into senescence
-
CrossRefPubMed
-
Sousa-Victor, P., Gutarra, S., Garćia-Prat, L., Rodriguez-Ubreva, J., Ortet, L., Ruiz-Bonilla, V., Jardí, M., Ballestar, E., Gonzá lez, S., Serrano, A.L. et al. (2014) Geriatric muscle stem cells switch reversible quiescence into senescence. Nature 506, 316-321 CrossRef PubMed
-
(2014)
Nature
, vol.506
, pp. 316-321
-
-
Sousa-Victor, P.1
Gutarra, S.2
Garćia-Prat, L.3
Rodriguez-Ubreva, J.4
Ortet, L.5
Ruiz-Bonilla, V.6
Jardí, M.7
Ballestar, E.8
González, S.9
Serrano, A.L.10
-
30
-
-
84867676626
-
The aged niche disrupts muscle stem cell quiescence
-
CrossRefPubMed
-
Chakkalakal, J.V., Jones, K.M., Basson, M.A. and Brack, A.S. (2012) The aged niche disrupts muscle stem cell quiescence. Nature 490, 355-360 CrossRef PubMed
-
(2012)
Nature
, vol.490
, pp. 355-360
-
-
Chakkalakal, J.V.1
Jones, K.M.2
Basson, M.A.3
Brack, A.S.4
-
31
-
-
13944261231
-
Rejuvenation of aged progenitor cells by exposure to a young systemic environment
-
Conboy, I.M., Conboy, M.J., Wagers, A.J., Girma, E.R., Weissman, I.L. and Rando, T.A. (2005) Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature 433, 760-764
-
(2005)
Nature
, vol.433
, pp. 760-764
-
-
Conboy, I.M.1
Conboy, M.J.2
Wagers, A.J.3
Girma, E.R.4
Weissman, I.L.5
Rando, T.A.6
-
32
-
-
84876909069
-
The ageing haematopoietic stem cell compartment
-
CrossRefPubMed
-
Geiger, H., de Haan, G. and Florian, M.C. (2013) The ageing haematopoietic stem cell compartment. Nat. Rev. Immunol. 13, 376-389 CrossRef PubMed
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 376-389
-
-
Geiger, H.1
De Haan, G.2
Florian, M.C.3
-
33
-
-
0036604275
-
Lack of antibody production following immunization in old age: Association with cd8+ cd28- t cell clonal expansions and an imbalance in the production of th1 and th2 cytokines
-
PubMed
-
Saurwein-Teissl, M., Lung, T.L., Marx, F., Gschosser, C., Asch, E., Blasko, I., Parson, W., Bock, G., Schonitzer, D., Trannoy, E. et al. (2002) Lack of antibody production following immunization in old age: association with CD8+ CD28- T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines. J. Immunol. 168, 5893-5899 PubMed
-
(2002)
J. Immunol.
, vol.168
, pp. 5893-5899
-
-
Saurwein-Teissl, M.1
Lung, T.L.2
Marx, F.3
Gschosser, C.4
Asch, E.5
Blasko, I.6
Parson, W.7
Bock, G.8
Schonitzer, D.9
Trannoy, E.10
-
34
-
-
23944441502
-
T cell development and receptor diversity during aging
-
CrossRefPubMed
-
Goronzy, J.J. and Weyand, C.M. (2005) T cell development and receptor diversity during aging. Curr. Opin. Immunol. 17, 468-475 CrossRef PubMed
-
(2005)
Curr. Opin. Immunol.
, vol.17
, pp. 468-475
-
-
Goronzy, J.J.1
Weyand, C.M.2
-
35
-
-
59049088629
-
B-cell diversity decreases in old age and is correlated with poor health status
-
CrossRefPubMed
-
Gibson, K.L., Wu, Y.C., Barnett, Y., Duggan, O., Vaughan, R., Kondeatis, E., Nilsson, B.O., Wikby, A., Kipling, D. and Dunn-Walters, D.K. (2009) B-cell diversity decreases in old age and is correlated with poor health status. Aging Cell 8, 18-25 CrossRef PubMed
-
(2009)
Aging Cell
, vol.8
, pp. 18-25
-
-
Gibson, K.L.1
Wu, Y.C.2
Barnett, Y.3
Duggan, O.4
Vaughan, R.5
Kondeatis, E.6
Nilsson, B.O.7
Wikby, A.8
Kipling, D.9
Dunn-Walters, D.K.10
-
36
-
-
0034613690
-
Age-associated characteristics of murine hematopoietic stem cells
-
CrossRefPubMed
-
Sudo, K., Ema, H., Morita, Y. and Nakauchi, H. (2000) Age-associated characteristics of murine hematopoietic stem cells. J. Exp. Med. 192, 1273-1280 CrossRef PubMed
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1273-1280
-
-
Sudo, K.1
Ema, H.2
Morita, Y.3
Nakauchi, H.4
-
37
-
-
21544467270
-
Cell intrinsic alterations underlie hematopoietic stem cell aging
-
CrossRefPubMed
-
Rossi, D.J., Bryder, D., Zahn, J.M., Ahlenius, H., Sonu, R., Wagers, A.J. and Weissman, I.L. (2005) Cell intrinsic alterations underlie hematopoietic stem cell aging. Proc. Natl. Acad. Sci. U.S.A. 102, 9194-9199 CrossRef PubMed
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 9194-9199
-
-
Rossi, D.J.1
Bryder, D.2
Zahn, J.M.3
Ahlenius, H.4
Sonu, R.5
Wagers, A.J.6
Weissman, I.L.7
-
38
-
-
33749365721
-
Increased hematopoietic stem cell mobilization in aged mice
-
CrossRefPubMed
-
Xing, Z., Ryan, M.A., Daria, D., Nattamai, K.J., Van Zant, G., Wang, L., Zheng, Y. and Geiger, H. (2006) Increased hematopoietic stem cell mobilization in aged mice. Blood 108, 2190-2197 CrossRef PubMed
-
(2006)
Blood
, vol.108
, pp. 2190-2197
-
-
Xing, Z.1
Ryan, M.A.2
Daria, D.3
Nattamai, K.J.4
Van Zant, G.5
Wang, L.6
Zheng, Y.7
Geiger, H.8
-
39
-
-
84860634046
-
Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation
-
CrossRefPubMed
-
Florian, M.C., Dorr, K., Niebel, A., Daria, D., Schrezenmeier, H., Rojewski, M., Filippi, M.D., Hasenberg, A., Gunzer, M., Scharffetter-Kochanek, K. et al. (2012) Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation. Cell Stem Cell 10, 520-530 CrossRef PubMed
-
(2012)
Cell Stem Cell
, vol.10
, pp. 520-530
-
-
Florian, M.C.1
Dorr, K.2
Niebel, A.3
Daria, D.4
Schrezenmeier, H.5
Rojewski, M.6
Filippi, M.D.7
Hasenberg, A.8
Gunzer, M.9
Scharffetter-Kochanek, K.10
-
40
-
-
84858649330
-
Rantes/ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing
-
CrossRefPubMed
-
Ergen, A.V., Boles, N.C. and Goodell, M.A. (2012) Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing. Blood 119, 2500-2509 CrossRef PubMed
-
(2012)
Blood
, vol.119
, pp. 2500-2509
-
-
Ergen, A.V.1
Boles, N.C.2
Goodell, M.A.3
-
41
-
-
84886283477
-
Regenerating the skin: A task for the heterogeneous stem cell pool and surrounding niche
-
CrossRefPubMed
-
Solanas, G. and Benitah, S.A. (2013) Regenerating the skin: a task for the heterogeneous stem cell pool and surrounding niche. Nat. Rev. Mol. Cell Biol. 14, 737-748 CrossRef PubMed
-
(2013)
Nat. Rev. Mol. Cell Biol.
, vol.14
, pp. 737-748
-
-
Solanas, G.1
Benitah, S.A.2
-
42
-
-
0024149039
-
Epithelial stem cells in vivo
-
CrossRefPubMed
-
Potten, C.S. and Morris, R.J. (1988) Epithelial stem cells in vivo. J. Cell Sci. Suppl. 10, 45-62 CrossRef PubMed
-
(1988)
J. Cell Sci. Suppl.
, vol.10
, pp. 45-62
-
-
Potten, C.S.1
Morris, R.J.2
-
43
-
-
0025313294
-
Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis
-
CrossRefPubMed
-
Cotsarelis, G., Sun, T.T. and Lavker, R.M. (1990) Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell 61, 1329-1337 CrossRef PubMed
-
(1990)
Cell
, vol.61
, pp. 1329-1337
-
-
Cotsarelis, G.1
Sun, T.T.2
Lavker, R.M.3
-
44
-
-
0347634454
-
Defining the epithelial stem cell niche in skin
-
CrossRefPubMed
-
Tumbar, T., Guasch, G., Greco, V., Blanpain, C., Lowry, W.E., Rendl, M. and Fuchs, E. (2004) Defining the epithelial stem cell niche in skin. Science 303, 359-363 CrossRef PubMed
-
(2004)
Science
, vol.303
, pp. 359-363
-
-
Tumbar, T.1
Guasch, G.2
Greco, V.3
Blanpain, C.4
Lowry, W.E.5
Rendl, M.6
Fuchs, E.7
-
45
-
-
60749125436
-
Epidermal homeostasis: A balancing act of stem cells in the skin
-
CrossRefPubMed
-
Blanpain, C. and Fuchs, E. (2009) Epidermal homeostasis: a balancing act of stem cells in the skin. Nat. Rev. Mol. Cell Biol. 10, 207-217 CrossRef PubMed
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 207-217
-
-
Blanpain, C.1
Fuchs, E.2
-
46
-
-
4444290010
-
Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche
-
CrossRefPubMed
-
Blanpain, C., Lowry, W.E., Geoghegan, A., Polak, L. and Fuchs, E. (2004) Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell 118, 635-648 CrossRef PubMed
-
(2004)
Cell
, vol.118
, pp. 635-648
-
-
Blanpain, C.1
Lowry, W.E.2
Geoghegan, A.3
Polak, L.4
Fuchs, E.5
-
47
-
-
1842529559
-
Capturing and profiling adult hair follicle stem cells
-
CrossRefPubMed
-
Morris, R.J., Liu, Y., Marles, L., Yang, Z., Trempus, C., Li, S., Lin, J.S., Sawicki, J.A. and Cotsarelis, G. (2004) Capturing and profiling adult hair follicle stem cells. Nat. Biotechnol. 22, 411-417 CrossRef PubMed
-
(2004)
Nat. Biotechnol.
, vol.22
, pp. 411-417
-
-
Morris, R.J.1
Liu, Y.2
Marles, L.3
Yang, Z.4
Trempus, C.5
Li, S.6
Lin, J.S.7
Sawicki, J.A.8
Cotsarelis, G.9
-
48
-
-
28644451449
-
Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis
-
CrossRefPubMed
-
Ito, M., Liu, Y., Yang, Z., Nguyen, J., Liang, F., Morris, R.J. and Cotsarelis, G. (2005) Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nat. Med. 11, 1351-1354 CrossRef PubMed
-
(2005)
Nat. Med.
, vol.11
, pp. 1351-1354
-
-
Ito, M.1
Liu, Y.2
Yang, Z.3
Nguyen, J.4
Liang, F.5
Morris, R.J.6
Cotsarelis, G.7
-
49
-
-
33748165316
-
The cell-surface marker mts24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells
-
CrossRefPubMed
-
Nijhof, J.G., Braun, K.M., Giangreco, A., van Pelt, C., Kawamoto, H., Boyd, R.L., Willemze, R., Mullenders, L.H., Watt, F.M., de Gruijl, F.R. et al. (2006) The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells. Development 133, 3027-3037 CrossRef PubMed
-
(2006)
Development
, vol.133
, pp. 3027-3037
-
-
Nijhof, J.G.1
Braun, K.M.2
Giangreco, A.3
Van Pelt, C.4
Kawamoto, H.5
Boyd, R.L.6
Willemze, R.7
Mullenders, L.H.8
Watt, F.M.9
De Gruijl, F.R.10
-
50
-
-
77949360959
-
Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin
-
CrossRefPubMed
-
Snippert, H.J., Haegebarth, A., Kasper, M., Jaks, V., van Es, J.H., Barker, N., van de Wetering, M., van den Born, M., Begthel, H., Vries, R.G. et al. (2010) Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin. Science 327, 1385-1389 CrossRef PubMed
-
(2010)
Science
, vol.327
, pp. 1385-1389
-
-
Snippert, H.J.1
Haegebarth, A.2
Kasper, M.3
Jaks, V.4
Van Es, J.H.5
Barker, N.6
Van De Wetering, M.7
Van Den Born, M.8
Begthel, H.9
Vries, R.G.10
-
51
-
-
42149097827
-
A distinct population of clonogenic and multipotent murine follicular keratinocytes residing in the upper isthmus
-
CrossRefPubMed
-
Jensen, U.B., Yan, X., Triel, C., Woo, S.H., Christensen, R. and Owens, D.M. (2008) A distinct population of clonogenic and multipotent murine follicular keratinocytes residing in the upper isthmus. J. Cell Sci. 121, 609-617 CrossRef PubMed
-
(2008)
J. Cell Sci.
, vol.121
, pp. 609-617
-
-
Jensen, U.B.1
Yan, X.2
Triel, C.3
Woo, S.H.4
Christensen, R.5
Owens, D.M.6
-
52
-
-
65349166258
-
Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis
-
CrossRefPubMed
-
Jensen, K.B., Collins, C.A., Nascimento, E., Tan, D.W., Frye, M., Itami, S. and Watt, F.M. (2009) Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis. Cell Stem Cell 4, 427-439 CrossRef PubMed
-
(2009)
Cell Stem Cell
, vol.4
, pp. 427-439
-
-
Jensen, K.B.1
Collins, C.A.2
Nascimento, E.3
Tan, D.W.4
Frye, M.5
Itami, S.6
Watt, F.M.7
-
53
-
-
33746729815
-
Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland
-
CrossRefPubMed
-
Horsley, V., O'Carroll, D., Tooze, R., Ohinata, Y., Saitou, M., Obukhanych, T., Nussenzweig, M., Tarakhovsky, A. and Fuchs, E. (2006) Blimp1 defines a progenitor population that governs cellular input to the sebaceous gland. Cell 126, 597-609 CrossRef PubMed
-
(2006)
Cell
, vol.126
, pp. 597-609
-
-
Horsley, V.1
O'Carroll, D.2
Tooze, R.3
Ohinata, Y.4
Saitou, M.5
Obukhanych, T.6
Nussenzweig, M.7
Tarakhovsky, A.8
Fuchs, E.9
-
54
-
-
55049112939
-
Lgr5 marks cycling, yet long-lived, hair follicle stem cells
-
CrossRefPubMed
-
Jaks, V., Barker, N., Kasper, M., van Es, J.H., Snippert, H.J., Clevers, H. and Toftgard, R. (2008) Lgr5 marks cycling, yet long-lived, hair follicle stem cells. Nat. Genet. 40, 1291-1299 CrossRef PubMed
-
(2008)
Nat. Genet.
, vol.40
, pp. 1291-1299
-
-
Jaks, V.1
Barker, N.2
Kasper, M.3
Van Es, J.H.4
Snippert, H.J.5
Clevers, H.6
Toftgard, R.7
-
55
-
-
0022543938
-
Structural and functional changes of normal aging skin
-
CrossRefPubMed
-
Fenske, N.A. and Lober, C.W. (1986) Structural and functional changes of normal aging skin. J. Am. Acad. Dermatol. 15, 571-585 CrossRef PubMed
-
(1986)
J. Am. Acad. Dermatol.
, vol.15
, pp. 571-585
-
-
Fenske, N.A.1
Lober, C.W.2
-
56
-
-
33744522589
-
Prevention and treatment of skin aging
-
CrossRefPubMed
-
McCullough, J.L. and Kelly, K.M. (2006) Prevention and treatment of skin aging. Ann. N.Y. Acad. Sci. 1067, 323-331 CrossRef PubMed
-
(2006)
Ann. N.Y. Acad. Sci.
, vol.1067
, pp. 323-331
-
-
McCullough, J.L.1
Kelly, K.M.2
-
57
-
-
40549103466
-
Epidermal stem cells are retained in vivo throughout skin aging
-
CrossRefPubMed
-
Giangreco, A., Qin, M., Pintar, J.E. and Watt, F.M. (2008) Epidermal stem cells are retained in vivo throughout skin aging. Aging Cell 7, 250-259 CrossRef PubMed
-
(2008)
Aging Cell
, vol.7
, pp. 250-259
-
-
Giangreco, A.1
Qin, M.2
Pintar, J.E.3
Watt, F.M.4
-
58
-
-
84890834283
-
Nfatc1 orchestrates aging in hair follicle stem cells
-
CrossRefPubMed
-
Keyes, B.E., Segal, J.P., Heller, E., Lien, W.H., Chang, C.Y., Guo, X., Oristian, D.S., Zheng, D. and Fuchs, E. (2013) Nfatc1 orchestrates aging in hair follicle stem cells. Proc. Natl. Acad. Sci. U.S.A. 110, E4950-E4959 CrossRef PubMed
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
-
-
Keyes, B.E.1
Segal, J.P.2
Heller, E.3
Lien, W.H.4
Chang, C.Y.5
Guo, X.6
Oristian, D.S.7
Zheng, D.8
Fuchs, E.9
-
59
-
-
0011478490
-
Three clonal types of keratinocyte with different capacities for multiplication
-
CrossRefPubMed
-
Barrandon, Y. and Green, H. (1987) Three clonal types of keratinocyte with different capacities for multiplication. Proc. Natl. Acad. Sci. U.S.A. 84, 2302-2306 CrossRef PubMed
-
(1987)
Proc. Natl. Acad. Sci. U.S.A.
, vol.84
, pp. 2302-2306
-
-
Barrandon, Y.1
Green, H.2
-
60
-
-
34447623393
-
Epidermal stem cells are resistant to cellular aging
-
CrossRefPubMed
-
Stern, M.M. and Bickenbach, J.R. (2007) Epidermal stem cells are resistant to cellular aging. Aging Cell 6, 439-452 CrossRef PubMed
-
(2007)
Aging Cell
, vol.6
, pp. 439-452
-
-
Stern, M.M.1
Bickenbach, J.R.2
-
61
-
-
84867208183
-
Age-associated inflammation inhibits epidermal stem cell function
-
CrossRefPubMed
-
Doles, J., Storer, M., Cozzuto, L., Roma, G. and Keyes, W.M. (2012) Age-associated inflammation inhibits epidermal stem cell function. Genes Dev. 26, 2144-2153 CrossRef PubMed
-
(2012)
Genes Dev.
, vol.26
, pp. 2144-2153
-
-
Doles, J.1
Storer, M.2
Cozzuto, L.3
Roma, G.4
Keyes, W.M.5
-
62
-
-
74049092761
-
Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin
-
CrossRefPubMed
-
Rittie, L., Stoll, S.W., Kang, S., Voorhees, J.J. and Fisher, G.J. (2009) Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin. Aging Cell 8, 738-751 CrossRef PubMed
-
(2009)
Aging Cell
, vol.8
, pp. 738-751
-
-
Rittie, L.1
Stoll, S.W.2
Kang, S.3
Voorhees, J.J.4
Fisher, G.J.5
-
63
-
-
79551607574
-
Np63α is an oncogene that targets chromatin remodeler lsh to drive skin stem cell proliferation and tumorigenesis
-
CrossRefPubMed
-
Keyes, W.M., Pecoraro, M., Aranda, V., Vernersson-Lindahl, E., Li, W., Vogel, H., Guo, X., Garcia, E.L., Michurina, T.V., Enikolopov, G. et al. (2011) -Np63α is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis. Cell Stem Cell 8, 164-176 CrossRef PubMed
-
(2011)
Cell Stem Cell
, vol.8
, pp. 164-176
-
-
Keyes, W.M.1
Pecoraro, M.2
Aranda, V.3
Vernersson-Lindahl, E.4
Li, W.5
Vogel, H.6
Guo, X.7
Garcia, E.L.8
Michurina, T.V.9
Enikolopov, G.10
-
64
-
-
79956317899
-
Identifying the cellular origin of squamous skin tumors
-
CrossRefPubMed
-
Lapouge, G., Youssef, K.K., Vokaer, B., Achouri, Y., Michaux, C., Sotiropoulou, P.A. and Blanpain, C. (2011) Identifying the cellular origin of squamous skin tumors. Proc. Natl. Acad. Sci. U.S.A. 108, 7431-7436 CrossRef PubMed
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 7431-7436
-
-
Lapouge, G.1
Youssef, K.K.2
Vokaer, B.3
Achouri, Y.4
Michaux, C.5
Sotiropoulou, P.A.6
Blanpain, C.7
-
65
-
-
79956317166
-
Defining the origins of ras/p53-mediated squamous cell carcinoma
-
CrossRefPubMed
-
White, A.C., Tran, K., Khuu, J., Dang, C., Cui, Y., Binder, S.W. and Lowry, W.E. (2011) Defining the origins of Ras/p53-mediated squamous cell carcinoma. Proc. Natl. Acad. Sci. U.S.A. 108, 7425-7430 CrossRef PubMed
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 7425-7430
-
-
White, A.C.1
Tran, K.2
Khuu, J.3
Dang, C.4
Cui, Y.5
Binder, S.W.6
Lowry, W.E.7
-
66
-
-
84881476621
-
Progeny of lgr5-expressing hair follicle stem cell contributes to papillomavirus-induced tumor development in epidermis
-
CrossRefPubMed
-
da Silva-Diz, V., Sole-Sanchez, S., Valdes-Gutierrez, A., Urpi, M., Riba-Artes, D., Penin, R.M., Pascual, G., Gonzalez-Suarez, E., Casanovas, O., Vinals, F. et al. (2013) Progeny of Lgr5-expressing hair follicle stem cell contributes to papillomavirus-induced tumor development in epidermis. Oncogene 32, 3732-3743 CrossRef PubMed
-
(2013)
Oncogene
, vol.32
, pp. 3732-3743
-
-
Da Silva-Diz, V.1
Sole-Sanchez, S.2
Valdes-Gutierrez, A.3
Urpi, M.4
Riba-Artes, D.5
Penin, R.M.6
Pascual, G.7
Gonzalez-Suarez, E.8
Casanovas, O.9
Vinals, F.10
-
67
-
-
84863723266
-
Stat3 can serve as a hit in the process of malignant transformation of primary cells
-
CrossRefPubMed
-
Demaria, M., Misale, S., Giorgi, C., Miano, V., Camporeale, A., Campisi, J., Pinton, P. and Poli, V. (2012) STAT3 can serve as a hit in the process of malignant transformation of primary cells. Cell Death Differ. 19, 1390-1397 CrossRef PubMed
-
(2012)
Cell Death Differ.
, vol.19
, pp. 1390-1397
-
-
Demaria, M.1
Misale, S.2
Giorgi, C.3
Miano, V.4
Camporeale, A.5
Campisi, J.6
Pinton, P.7
Poli, V.8
-
68
-
-
33748327046
-
P16ink4a is a robust in vivo biomarker of cellular aging in human skin
-
CrossRefPubMed
-
Ressler, S., Bartkova, J., Niederegger, H., Bartek, J., Scharffetter-Kochanek, K., Jansen-Durr, P. and Wlaschek, M. (2006) p16INK4A is a robust in vivo biomarker of cellular aging in human skin. Aging Cell 5, 379-389 CrossRef PubMed
-
(2006)
Aging Cell
, vol.5
, pp. 379-389
-
-
Ressler, S.1
Bartkova, J.2
Niederegger, H.3
Bartek, J.4
Scharffetter-Kochanek, K.5
Jansen-Durr, P.6
Wlaschek, M.7
-
69
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
CrossRefPubMed
-
Dimri, G.P., Lee, X., Basile, G., Acosta, M., Scott, G., Roskelley, C., Medrano, E.E., Linskens, M., Rubelj, I., Pereira-Smith, O. et al. (1995) A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl. Acad. Sci. U.S.A. 92, 9363-9367 CrossRef PubMed
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelley, C.6
Medrano, E.E.7
Linskens, M.8
Rubelj, I.9
Pereira-Smith, O.10
-
70
-
-
84856090875
-
Aging, rejuvenation, and epigenetic reprogramming: Resetting the aging clock
-
CrossRefPubMed
-
Rando, T.A. and Chang, H.Y. (2012) Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock. Cell 148, 46-57 CrossRef PubMed
-
(2012)
Cell
, vol.148
, pp. 46-57
-
-
Rando, T.A.1
Chang, H.Y.2
|