메뉴 건너뛰기




Volumn 389, Issue 1-2, 2014, Pages 58-64

Astrocyte-derived growth factors and estrogen neuroprotection: Role of transforming growth factor-α in estrogen-induced upregulation of glutamate transporters in astrocytes

Author keywords

Astrocytes; Estrogen; GLAST; GLT 1; Neuroprotection; TGF

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; EXCITATORY AMINO ACID TRANSPORTER; G PROTEIN COUPLED RECEPTOR 30; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGANESE; MESSENGER RNA; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TAMOXIFEN; TRANSFORMING GROWTH FACTOR ALPHA; VESICULAR GLUTAMATE TRANSPORTER 1; NEUROPROTECTIVE AGENT; SIGNAL PEPTIDE;

EID: 84901478804     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2014.01.010     Document Type: Review
Times cited : (61)

References (103)
  • 2
    • 59649115254 scopus 로고    scopus 로고
    • Neuroscience: glia - more than just brain glue
    • Allen N.J., Barres B.A. Neuroscience: glia - more than just brain glue. Nature 2009, 457:675-677.
    • (2009) Nature , vol.457 , pp. 675-677
    • Allen, N.J.1    Barres, B.A.2
  • 4
    • 80053383728 scopus 로고    scopus 로고
    • 17Beta-estradiol differentially protects cortical pericontusional zone from programmed cell death after traumatic cerebral contusion at distinct stages via non-genomic and genomic pathways
    • Bao Y.J., Li L.Z., Li X.G., Wang Y.J. 17Beta-estradiol differentially protects cortical pericontusional zone from programmed cell death after traumatic cerebral contusion at distinct stages via non-genomic and genomic pathways. Mol. Cell. Neurosci. 2011, 48:185-194.
    • (2011) Mol. Cell. Neurosci. , vol.48 , pp. 185-194
    • Bao, Y.J.1    Li, L.Z.2    Li, X.G.3    Wang, Y.J.4
  • 6
    • 0028341483 scopus 로고
    • Brain-derived neurotrophic factor protects against ischemic cell damage in rat hippocampus
    • Beck T., Lindholm D., Castren E., Wree A. Brain-derived neurotrophic factor protects against ischemic cell damage in rat hippocampus. J. Cereb. Blood Flow Metab. 1994, 14:689-692.
    • (1994) J. Cereb. Blood Flow Metab. , vol.14 , pp. 689-692
    • Beck, T.1    Lindholm, D.2    Castren, E.3    Wree, A.4
  • 7
    • 0036593191 scopus 로고    scopus 로고
    • Oestrogen as a neuroprotective hormone
    • Behl C. Oestrogen as a neuroprotective hormone. Nat. Rev. Neurosci. 2002, 3:433-442.
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 433-442
    • Behl, C.1
  • 8
    • 0344492699 scopus 로고    scopus 로고
    • Estrogen protects neuronal cells from the cytotoxicity induced by acetylcholinesterase-amyloid complexes
    • Bonnefont A.B., Munoz F.J., Inestrosa N.C. Estrogen protects neuronal cells from the cytotoxicity induced by acetylcholinesterase-amyloid complexes. FEBS Lett. 1998, 441:220-224.
    • (1998) FEBS Lett. , vol.441 , pp. 220-224
    • Bonnefont, A.B.1    Munoz, F.J.2    Inestrosa, N.C.3
  • 10
    • 34247150317 scopus 로고    scopus 로고
    • Neurotrophic and neuroprotective actions of estrogen: basic mechanisms and clinical implications
    • Brann D.W., Dhandapani K., Wakade C., Mahesh V.B., Khan M.M. Neurotrophic and neuroprotective actions of estrogen: basic mechanisms and clinical implications. Steroids 2007, 72:381-405.
    • (2007) Steroids , vol.72 , pp. 381-405
    • Brann, D.W.1    Dhandapani, K.2    Wakade, C.3    Mahesh, V.B.4    Khan, M.M.5
  • 11
    • 0034127135 scopus 로고    scopus 로고
    • Estrogen-astrocyte-luteinizing hormone-releasing hormone signaling: a role for transforming growth factor-beta(1)
    • Buchanan C.D., Mahesh V.B., Brann D.W. Estrogen-astrocyte-luteinizing hormone-releasing hormone signaling: a role for transforming growth factor-beta(1). Biol. Reprod. 2000, 62:1710-1721.
    • (2000) Biol. Reprod. , vol.62 , pp. 1710-1721
    • Buchanan, C.D.1    Mahesh, V.B.2    Brann, D.W.3
  • 12
    • 7944227783 scopus 로고    scopus 로고
    • 17 Beta-estradiol prevents focal cerebral ischemic damages via activation of Akt and CREB in association with reduced PTEN phosphorylation in rats
    • Choi Y.C., Lee J.H., Hong K.W., Lee K.S. 17 Beta-estradiol prevents focal cerebral ischemic damages via activation of Akt and CREB in association with reduced PTEN phosphorylation in rats. Fundam. Clin. Pharmacol. 2004, 18:547-557.
    • (2004) Fundam. Clin. Pharmacol. , vol.18 , pp. 547-557
    • Choi, Y.C.1    Lee, J.H.2    Hong, K.W.3    Lee, K.S.4
  • 13
    • 84876668625 scopus 로고    scopus 로고
    • Emerging roles of astrocytes in neural circuit development
    • Clarke L.E., Barres B.A. Emerging roles of astrocytes in neural circuit development. Nat. Rev. Neurosci. 2013, 14:311-321.
    • (2013) Nat. Rev. Neurosci. , vol.14 , pp. 311-321
    • Clarke, L.E.1    Barres, B.A.2
  • 14
    • 2642580113 scopus 로고    scopus 로고
    • Estrogen-astrocyte interactions: implications for neuroprotection
    • Dhandapani K.M., Brann D.W. Estrogen-astrocyte interactions: implications for neuroprotection. BMC Neurosci. 2002, 3:6.
    • (2002) BMC Neurosci. , vol.3 , pp. 6
    • Dhandapani, K.M.1    Brann, D.W.2
  • 15
    • 0038281501 scopus 로고    scopus 로고
    • Neuroprotective effects of estrogen and tamoxifen in vitro: a facilitative role for glia?
    • Dhandapani K., Brann D. Neuroprotective effects of estrogen and tamoxifen in vitro: a facilitative role for glia?. Endocrine 2003, 21:59-66.
    • (2003) Endocrine , vol.21 , pp. 59-66
    • Dhandapani, K.1    Brann, D.2
  • 16
    • 33845590845 scopus 로고    scopus 로고
    • Role of astrocytes in estrogen-mediated neuroprotection
    • Dhandapani K.M., Brann D.W. Role of astrocytes in estrogen-mediated neuroprotection. Exp. Gerontol. 2007, 42:70-75.
    • (2007) Exp. Gerontol. , vol.42 , pp. 70-75
    • Dhandapani, K.M.1    Brann, D.W.2
  • 17
    • 0242290324 scopus 로고    scopus 로고
    • Astrocyte protection of neurons: role of transforming growth factor-beta signaling via a c-Jun-AP-1 protective pathway
    • Dhandapani K.M., Hadman M., De Sevilla L., Wade M.F., Mahesh V.B., Brann D.W. Astrocyte protection of neurons: role of transforming growth factor-beta signaling via a c-Jun-AP-1 protective pathway. J. Biol. Chem. 2003, 278:43329-43339.
    • (2003) J. Biol. Chem. , vol.278 , pp. 43329-43339
    • Dhandapani, K.M.1    Hadman, M.2    De Sevilla, L.3    Wade, M.F.4    Mahesh, V.B.5    Brann, D.W.6
  • 18
    • 18844376360 scopus 로고    scopus 로고
    • Astrocyte-derived transforming growth factor-{beta} mediates the neuroprotective effects of 17{beta}-estradiol: involvement of nonclassical genomic signaling pathways
    • Dhandapani K.M., Wade F.M., Mahesh V.B., Brann D.W. Astrocyte-derived transforming growth factor-{beta} mediates the neuroprotective effects of 17{beta}-estradiol: involvement of nonclassical genomic signaling pathways. Endocrinology 2005, 146:2749-2759.
    • (2005) Endocrinology , vol.146 , pp. 2749-2759
    • Dhandapani, K.M.1    Wade, F.M.2    Mahesh, V.B.3    Brann, D.W.4
  • 19
    • 84864357300 scopus 로고    scopus 로고
    • The neuroprotective functions of transforming growth factor Beta proteins
    • Dobolyi A., Vincze C., Pal G., Lovas G. The neuroprotective functions of transforming growth factor Beta proteins. Int. J. Mol. Sci. 2012, 13:8219-8258.
    • (2012) Int. J. Mol. Sci. , vol.13 , pp. 8219-8258
    • Dobolyi, A.1    Vincze, C.2    Pal, G.3    Lovas, G.4
  • 23
    • 33646779843 scopus 로고    scopus 로고
    • Differential modulation of estrogen receptors (ERs) in ischemic brain injury: a role for ERalpha in estradiol-mediated protection against delayed cell death
    • Dubal D.B., Rau S.W., Shughrue P.J., Zhu H., Yu J., Cashion A.B., Suzuki S., Gerhold L.M., Bottner M.B., Dubal S.B., et al. Differential modulation of estrogen receptors (ERs) in ischemic brain injury: a role for ERalpha in estradiol-mediated protection against delayed cell death. Endocrinology 2006, 147:3076-3084.
    • (2006) Endocrinology , vol.147 , pp. 3076-3084
    • Dubal, D.B.1    Rau, S.W.2    Shughrue, P.J.3    Zhu, H.4    Yu, J.5    Cashion, A.B.6    Suzuki, S.7    Gerhold, L.M.8    Bottner, M.B.9    Dubal, S.B.10
  • 24
    • 0028343330 scopus 로고
    • Gonadal hormone regulation of insulin-like growth factor-I-like immunoreactivity in hypothalamic astroglia of developing and adult rats
    • Duenas M., Luquin S., Chowen J.A., Torres-Aleman I., Naftolin F., Garcia-Segura L.M. Gonadal hormone regulation of insulin-like growth factor-I-like immunoreactivity in hypothalamic astroglia of developing and adult rats. Neuroendocrinology 1994, 59:528-538.
    • (1994) Neuroendocrinology , vol.59 , pp. 528-538
    • Duenas, M.1    Luquin, S.2    Chowen, J.A.3    Torres-Aleman, I.4    Naftolin, F.5    Garcia-Segura, L.M.6
  • 26
    • 36448946877 scopus 로고    scopus 로고
    • Estrogen receptor beta agonist diarylpropiolnitrile (DPN) does not mediate neuroprotection in a rat model of permanent focal ischemia
    • Farr T.D., Carswell H.V., Gsell W., Macrae I.M. Estrogen receptor beta agonist diarylpropiolnitrile (DPN) does not mediate neuroprotection in a rat model of permanent focal ischemia. Brain Res. 2007, 1185:275-282.
    • (2007) Brain Res. , vol.1185 , pp. 275-282
    • Farr, T.D.1    Carswell, H.V.2    Gsell, W.3    Macrae, I.M.4
  • 27
    • 0036320770 scopus 로고    scopus 로고
    • Estrogen-mediated neuroprotection against beta-amyloid toxicity requires expression of estrogen receptor alpha or beta and activation of the MAPK pathway
    • Fitzpatrick J.L., Mize A.L., Wade C.B., Harris J.A., Shapiro R.A., Dorsa D.M. Estrogen-mediated neuroprotection against beta-amyloid toxicity requires expression of estrogen receptor alpha or beta and activation of the MAPK pathway. J. Neurochem. 2002, 82:674-682.
    • (2002) J. Neurochem. , vol.82 , pp. 674-682
    • Fitzpatrick, J.L.1    Mize, A.L.2    Wade, C.B.3    Harris, J.A.4    Shapiro, R.A.5    Dorsa, D.M.6
  • 28
    • 0033216112 scopus 로고    scopus 로고
    • Ovariectomy of adult rats leads to increased expression of astrocytic basic fibroblast growth factor in the ventral tegmental area and in dopaminergic projection regions of the entorhinal and prefrontal cortex
    • Flores C., Salmaso N., Cain S., Rodaros D., Stewart J. Ovariectomy of adult rats leads to increased expression of astrocytic basic fibroblast growth factor in the ventral tegmental area and in dopaminergic projection regions of the entorhinal and prefrontal cortex. J. Neurosci. 1999, 19:8665-8673.
    • (1999) J. Neurosci. , vol.19 , pp. 8665-8673
    • Flores, C.1    Salmaso, N.2    Cain, S.3    Rodaros, D.4    Stewart, J.5
  • 29
    • 0036798756 scopus 로고    scopus 로고
    • Oestrogens, via transforming growth factor alpha, modulate basic fibroblast growth factor synthesis in hypothalamic astrocytes: in vitro observations
    • Galbiati M., Martini L., Melcangi R.C. Oestrogens, via transforming growth factor alpha, modulate basic fibroblast growth factor synthesis in hypothalamic astrocytes: in vitro observations. J. Neuroendocrinol. 2002, 14:829-835.
    • (2002) J. Neuroendocrinol. , vol.14 , pp. 829-835
    • Galbiati, M.1    Martini, L.2    Melcangi, R.C.3
  • 32
    • 77955918599 scopus 로고    scopus 로고
    • Estrogen receptor alpha and G-protein coupled receptor 30 mediate the neuroprotective effects of 17beta-estradiol in novel murine hippocampal cell models
    • Gingerich S., Kim G.L., Chalmers J.A., Koletar M.M., Wang X., Wang Y., Belsham D.D. Estrogen receptor alpha and G-protein coupled receptor 30 mediate the neuroprotective effects of 17beta-estradiol in novel murine hippocampal cell models. Neuroscience 2010, 170:54-66.
    • (2010) Neuroscience , vol.170 , pp. 54-66
    • Gingerich, S.1    Kim, G.L.2    Chalmers, J.A.3    Koletar, M.M.4    Wang, X.5    Wang, Y.6    Belsham, D.D.7
  • 33
    • 0033152867 scopus 로고    scopus 로고
    • Estrogen and NGF synergistically protect terminally differentiated, ERalpha-transfected PC12 cells from apoptosis
    • Gollapudi L., Oblinger M.M. Estrogen and NGF synergistically protect terminally differentiated, ERalpha-transfected PC12 cells from apoptosis. J. Neurosci. Res. 1999, 56:471-481.
    • (1999) J. Neurosci. Res. , vol.56 , pp. 471-481
    • Gollapudi, L.1    Oblinger, M.M.2
  • 34
    • 0034237128 scopus 로고    scopus 로고
    • Neuroprotective effects of estrogens: potential mechanisms of action
    • Green P.S., Simpkins J.W. Neuroprotective effects of estrogens: potential mechanisms of action. Int. J. Dev. Neurosci. 2000, 18:347-358.
    • (2000) Int. J. Dev. Neurosci. , vol.18 , pp. 347-358
    • Green, P.S.1    Simpkins, J.W.2
  • 35
    • 77957090798 scopus 로고    scopus 로고
    • Reactive astrocytes as therapeutic targets for CNS disorders
    • Hamby M.E., Sofroniew M.V. Reactive astrocytes as therapeutic targets for CNS disorders. Neurotherapeutics 2010, 7:494-506.
    • (2010) Neurotherapeutics , vol.7 , pp. 494-506
    • Hamby, M.E.1    Sofroniew, M.V.2
  • 36
    • 30444434216 scopus 로고    scopus 로고
    • Tamoxifen (ICI46,474) as a targeted therapy to treat and prevent breast cancer
    • Jordan V.C. Tamoxifen (ICI46,474) as a targeted therapy to treat and prevent breast cancer. Br. J. Pharmacol. 2006, 147(Suppl. 1):S269-S276.
    • (2006) Br. J. Pharmacol. , vol.147 , Issue.SUPPL. 1
    • Jordan, V.C.1
  • 37
    • 33847062554 scopus 로고    scopus 로고
    • MAPK signaling is critical to estradiol protection of CA1 neurons in global ischemia
    • Jover-Mengual T., Zukin R.S., Etgen A.M. MAPK signaling is critical to estradiol protection of CA1 neurons in global ischemia. Endocrinology 2007, 148:1131-1143.
    • (2007) Endocrinology , vol.148 , pp. 1131-1143
    • Jover-Mengual, T.1    Zukin, R.S.2    Etgen, A.M.3
  • 38
    • 77549084058 scopus 로고    scopus 로고
    • Acute estradiol protects CA1 neurons from ischemia-induced apoptotic cell death via the PI3K/Akt pathway
    • Jover-Mengual T., Miyawaki T., Latuszek A., Alborch E., Zukin R.S., Etgen A.M. Acute estradiol protects CA1 neurons from ischemia-induced apoptotic cell death via the PI3K/Akt pathway. Brain Res. 2010, 1321:1-12.
    • (2010) Brain Res. , vol.1321 , pp. 1-12
    • Jover-Mengual, T.1    Miyawaki, T.2    Latuszek, A.3    Alborch, E.4    Zukin, R.S.5    Etgen, A.M.6
  • 39
    • 0034353578 scopus 로고    scopus 로고
    • What role(s) for TGFalpha in the central nervous system?
    • Junier M.P. What role(s) for TGFalpha in the central nervous system?. Prog. Neurobiol. 2000, 62:443-473.
    • (2000) Prog. Neurobiol. , vol.62 , pp. 443-473
    • Junier, M.P.1
  • 41
    • 1542722935 scopus 로고    scopus 로고
    • Alterations in IGF-I, BDNF and NT-3 levels following experimental brain trauma and the effect of IGF-I administration
    • Kazanis I., Giannakopoulou M., Philippidis H., Stylianopoulou F. Alterations in IGF-I, BDNF and NT-3 levels following experimental brain trauma and the effect of IGF-I administration. Exp. Neurol. 2004, 186:221-234.
    • (2004) Exp. Neurol. , vol.186 , pp. 221-234
    • Kazanis, I.1    Giannakopoulou, M.2    Philippidis, H.3    Stylianopoulou, F.4
  • 42
    • 67449123067 scopus 로고    scopus 로고
    • Control of CNS neuronal excitability by estrogens via membrane-initiated signaling
    • Kelly M.J., Ronnekleiv O.K. Control of CNS neuronal excitability by estrogens via membrane-initiated signaling. Mol. Cell. Endocrinol. 2009, 308:17-25.
    • (2009) Mol. Cell. Endocrinol. , vol.308 , pp. 17-25
    • Kelly, M.J.1    Ronnekleiv, O.K.2
  • 43
    • 79960689550 scopus 로고    scopus 로고
    • Role of excitatory amino acid transporter-2 (EAAT2) and glutamate in neurodegeneration: opportunities for developing novel therapeutics
    • Kim K., Lee S.G., Kegelman T.P., Su Z.Z., Das S.K., Dash R., Dasgupta S., Barral P.M., Hedvat M., Diaz P., et al. Role of excitatory amino acid transporter-2 (EAAT2) and glutamate in neurodegeneration: opportunities for developing novel therapeutics. J. Cell. Physiol. 2011, 226:2484-2493.
    • (2011) J. Cell. Physiol. , vol.226 , pp. 2484-2493
    • Kim, K.1    Lee, S.G.2    Kegelman, T.P.3    Su, Z.Z.4    Das, S.K.5    Dash, R.6    Dasgupta, S.7    Barral, P.M.8    Hedvat, M.9    Diaz, P.10
  • 46
    • 77957345404 scopus 로고    scopus 로고
    • Membrane estrogen receptors stimulate intracellular calcium release and progesterone synthesis in hypothalamic astrocytes
    • Kuo J., Hamid N., Bondar G., Prossnitz E.R., Micevych P. Membrane estrogen receptors stimulate intracellular calcium release and progesterone synthesis in hypothalamic astrocytes. J. Neurosci. 2010, 30:12950-12957.
    • (2010) J. Neurosci. , vol.30 , pp. 12950-12957
    • Kuo, J.1    Hamid, N.2    Bondar, G.3    Prossnitz, E.R.4    Micevych, P.5
  • 47
    • 63649135792 scopus 로고    scopus 로고
    • Estradiol rescues neurons from global ischemia-induced cell death: multiple cellular pathways of neuroprotection
    • Lebesgue D., Chevaleyre V., Zukin R.S., Etgen A.M. Estradiol rescues neurons from global ischemia-induced cell death: multiple cellular pathways of neuroprotection. Steroids 2009, 74:555-561.
    • (2009) Steroids , vol.74 , pp. 555-561
    • Lebesgue, D.1    Chevaleyre, V.2    Zukin, R.S.3    Etgen, A.M.4
  • 48
    • 77649153329 scopus 로고    scopus 로고
    • Acute administration of non-classical estrogen receptor agonists attenuates ischemia-induced hippocampal neuron loss in middle-aged female rats
    • Lebesgue D., Traub M., De Butte-Smith M., Chen C., Zukin R.S., Kelly M.J., Etgen A.M. Acute administration of non-classical estrogen receptor agonists attenuates ischemia-induced hippocampal neuron loss in middle-aged female rats. PLoS ONE 2010, 5:e8642.
    • (2010) PLoS ONE , vol.5
    • Lebesgue, D.1    Traub, M.2    De Butte-Smith, M.3    Chen, C.4    Zukin, R.S.5    Kelly, M.J.6    Etgen, A.M.7
  • 49
    • 0035040148 scopus 로고    scopus 로고
    • Neurotrophic and neuroprotective actions of estrogens and their therapeutic implications
    • Lee S.J., McEwen B.S. Neurotrophic and neuroprotective actions of estrogens and their therapeutic implications. Annu. Rev. Pharmacol. Toxicol. 2001, 41:569-591.
    • (2001) Annu. Rev. Pharmacol. Toxicol. , vol.41 , pp. 569-591
    • Lee, S.J.1    McEwen, B.S.2
  • 50
    • 67649552763 scopus 로고    scopus 로고
    • Estrogen and tamoxifen reverse manganese-induced glutamate transporter impairment in astrocytes
    • Lee E.S., Sidoryk M., Jiang H., Yin Z., Aschner M. Estrogen and tamoxifen reverse manganese-induced glutamate transporter impairment in astrocytes. J. Neurochem. 2009, 110:530-544.
    • (2009) J. Neurochem. , vol.110 , pp. 530-544
    • Lee, E.S.1    Sidoryk, M.2    Jiang, H.3    Yin, Z.4    Aschner, M.5
  • 51
    • 67649221617 scopus 로고    scopus 로고
    • Estrogen and tamoxifen protect against Mn-induced toxicity in rat cortical primary cultures of neurons and astrocytes
    • Lee E.S., Yin Z., Milatovic D., Jiang H., Aschner M. Estrogen and tamoxifen protect against Mn-induced toxicity in rat cortical primary cultures of neurons and astrocytes. Toxicol. Sci. 2009, 110:156-167.
    • (2009) Toxicol. Sci. , vol.110 , pp. 156-167
    • Lee, E.S.1    Yin, Z.2    Milatovic, D.3    Jiang, H.4    Aschner, M.5
  • 53
    • 84860653702 scopus 로고    scopus 로고
    • Transforming growth factor-alpha mediates estrogen-induced upregulation of glutamate transporter GLT-1 in rat primary astrocytes
    • Lee E., Sidoryk-Wegrzynowicz M., Yin Z., Webb A., Son D.S., Aschner M. Transforming growth factor-alpha mediates estrogen-induced upregulation of glutamate transporter GLT-1 in rat primary astrocytes. Glia 2012, 60:1024-1036.
    • (2012) Glia , vol.60 , pp. 1024-1036
    • Lee, E.1    Sidoryk-Wegrzynowicz, M.2    Yin, Z.3    Webb, A.4    Son, D.S.5    Aschner, M.6
  • 54
    • 0036318856 scopus 로고    scopus 로고
    • Effects of estrogen treatment on glutamate uptake in cultured human astrocytes derived from cortex of Alzheimer's disease patients
    • Liang Z., Valla J., Sefidvash-Hockley S., Rogers J., Li R. Effects of estrogen treatment on glutamate uptake in cultured human astrocytes derived from cortex of Alzheimer's disease patients. J. Neurochem. 2002, 80:807-814.
    • (2002) J. Neurochem. , vol.80 , pp. 807-814
    • Liang, Z.1    Valla, J.2    Sefidvash-Hockley, S.3    Rogers, J.4    Li, R.5
  • 55
    • 84865783553 scopus 로고    scopus 로고
    • Glutamate transporter EAAT2: a new target for the treatment of neurodegenerative diseases
    • Lin C.L., Kong Q., Cuny G.D., Glicksman M.A. Glutamate transporter EAAT2: a new target for the treatment of neurodegenerative diseases. Future Med. Chem. 2012, 4:1689-1700.
    • (2012) Future Med. Chem. , vol.4 , pp. 1689-1700
    • Lin, C.L.1    Kong, Q.2    Cuny, G.D.3    Glicksman, M.A.4
  • 57
    • 80052083256 scopus 로고    scopus 로고
    • Neuroprotective effects of oestrogen against oxidative toxicity through activation of G-protein-coupled receptor 30 receptor
    • Liu S.B., Han J., Zhang N., Tian Z., Li X.B., Zhao M.G. Neuroprotective effects of oestrogen against oxidative toxicity through activation of G-protein-coupled receptor 30 receptor. Clin. Exp. Pharmacol. Physiol. 2011, 38:577-585.
    • (2011) Clin. Exp. Pharmacol. Physiol. , vol.38 , pp. 577-585
    • Liu, S.B.1    Han, J.2    Zhang, N.3    Tian, Z.4    Li, X.B.5    Zhao, M.G.6
  • 58
    • 84859299181 scopus 로고    scopus 로고
    • G-protein-coupled receptor 30 mediates rapid neuroprotective effects of estrogen via depression of NR2B-containing NMDA receptors
    • Liu S.B., Zhang N., Guo Y.Y., Zhao R., Shi T.Y., Feng S.F., Wang S.Q., Yang Q., Li X.Q., Wu Y.M., et al. G-protein-coupled receptor 30 mediates rapid neuroprotective effects of estrogen via depression of NR2B-containing NMDA receptors. J. Neurosci. 2012, 32:4887-4900.
    • (2012) J. Neurosci. , vol.32 , pp. 4887-4900
    • Liu, S.B.1    Zhang, N.2    Guo, Y.Y.3    Zhao, R.4    Shi, T.Y.5    Feng, S.F.6    Wang, S.Q.7    Yang, Q.8    Li, X.Q.9    Wu, Y.M.10
  • 59
    • 0027983492 scopus 로고
    • Region-specific regulation of transforming growth factor alpha (TGF alpha) gene expression in astrocytes of the neuroendocrine brain
    • Ma Y.J., Berg-von der Emde K., Moholt-Siebert M., Hill D.F., Ojeda S.R. Region-specific regulation of transforming growth factor alpha (TGF alpha) gene expression in astrocytes of the neuroendocrine brain. J. Neurosci. 1994, 14:5644-5651.
    • (1994) J. Neurosci. , vol.14 , pp. 5644-5651
    • Ma, Y.J.1    Berg-von der Emde, K.2    Moholt-Siebert, M.3    Hill, D.F.4    Ojeda, S.R.5
  • 61
    • 63249111135 scopus 로고    scopus 로고
    • Role of estrogen receptor alpha in membrane-initiated signaling in neural cells: interaction with IGF-1 receptor
    • Marin R., Diaz M., Alonso R., Sanz A., Arevalo M.A., Garcia-Segura L.M. Role of estrogen receptor alpha in membrane-initiated signaling in neural cells: interaction with IGF-1 receptor. J. Steroid Biochem. Mol. Biol. 2009, 114:2-7.
    • (2009) J. Steroid Biochem. Mol. Biol. , vol.114 , pp. 2-7
    • Marin, R.1    Diaz, M.2    Alonso, R.3    Sanz, A.4    Arevalo, M.A.5    Garcia-Segura, L.M.6
  • 62
    • 33846066888 scopus 로고    scopus 로고
    • Estrogen signaling multiple pathways to impact gene transcription
    • Marino M., Galluzzo P., Ascenzi P. Estrogen signaling multiple pathways to impact gene transcription. Curr. Genomics 2006, 7:497-508.
    • (2006) Curr. Genomics , vol.7 , pp. 497-508
    • Marino, M.1    Galluzzo, P.2    Ascenzi, P.3
  • 63
    • 33644807832 scopus 로고    scopus 로고
    • Interactions of insulin-like growth factor-I and estrogen in the brain
    • Mendez P., Cardona-Gomez G.P., Garcia-Segura L.M. Interactions of insulin-like growth factor-I and estrogen in the brain. Adv. Exp. Med. Biol. 2005, 567:285-303.
    • (2005) Adv. Exp. Med. Biol. , vol.567 , pp. 285-303
    • Mendez, P.1    Cardona-Gomez, G.P.2    Garcia-Segura, L.M.3
  • 64
    • 0035341498 scopus 로고    scopus 로고
    • Neuroprotection mediated by glial cell line-derived neurotrophic factor: involvement of a reduction of NMDA-induced calcium influx by the mitogen-activated protein kinase pathway
    • Nicole O., Ali C., Docagne F., Plawinski L., MacKenzie E.T., Vivien D., Buisson A. Neuroprotection mediated by glial cell line-derived neurotrophic factor: involvement of a reduction of NMDA-induced calcium influx by the mitogen-activated protein kinase pathway. J. Neurosci. 2001, 21:3024-3033.
    • (2001) J. Neurosci. , vol.21 , pp. 3024-3033
    • Nicole, O.1    Ali, C.2    Docagne, F.3    Plawinski, L.4    MacKenzie, E.T.5    Vivien, D.6    Buisson, A.7
  • 65
    • 0027407036 scopus 로고
    • Basic fibroblast growth factor protects against hypoxia-ischemia and NMDA neurotoxicity in neonatal rats
    • Nozaki K., Finklestein S.P., Beal M.F. Basic fibroblast growth factor protects against hypoxia-ischemia and NMDA neurotoxicity in neonatal rats. J. Cereb. Blood Flow Metab. 1993, 13:221-228.
    • (1993) J. Cereb. Blood Flow Metab. , vol.13 , pp. 221-228
    • Nozaki, K.1    Finklestein, S.P.2    Beal, M.F.3
  • 66
    • 0035106245 scopus 로고    scopus 로고
    • Tamoxifen inhibits nitrotyrosine formation after reversible middle cerebral artery occlusion in the rat
    • Osuka K., Feustel P.J., Mongin A.A., Tranmer B.I., Kimelberg H.K. Tamoxifen inhibits nitrotyrosine formation after reversible middle cerebral artery occlusion in the rat. J. Neurochem. 2001, 76:1842-1850.
    • (2001) J. Neurochem. , vol.76 , pp. 1842-1850
    • Osuka, K.1    Feustel, P.J.2    Mongin, A.A.3    Tranmer, B.I.4    Kimelberg, H.K.5
  • 67
    • 0033002368 scopus 로고    scopus 로고
    • Manganese neurotoxicity: a review of clinical features, imaging and pathology
    • Pal P.K., Samii A., Calne D.B. Manganese neurotoxicity: a review of clinical features, imaging and pathology. Neurotoxicology 1999, 20:227-238.
    • (1999) Neurotoxicology , vol.20 , pp. 227-238
    • Pal, P.K.1    Samii, A.2    Calne, D.B.3
  • 68
    • 0034788741 scopus 로고    scopus 로고
    • Co-culture with astrocytes or microglia protects metabolically impaired neurons
    • Park L.C.H., Zhang H., Gibson G.E. Co-culture with astrocytes or microglia protects metabolically impaired neurons. Mech. Ageing Dev. 2001, 123:21-27.
    • (2001) Mech. Ageing Dev. , vol.123 , pp. 21-27
    • Park, L.C.H.1    Zhang, H.2    Gibson, G.E.3
  • 69
    • 22744439476 scopus 로고    scopus 로고
    • Regulation of glutamate transporter GLAST and GLT-1 expression in astrocytes by estrogen
    • Pawlak J., Brito V., Kuppers E., Beyer C. Regulation of glutamate transporter GLAST and GLT-1 expression in astrocytes by estrogen. Brain Res. Mol. Brain Res. 2005, 138:1-7.
    • (2005) Brain Res. Mol. Brain Res. , vol.138 , pp. 1-7
    • Pawlak, J.1    Brito, V.2    Kuppers, E.3    Beyer, C.4
  • 70
    • 20044373886 scopus 로고    scopus 로고
    • Estrogen receptor-alpha is associated with the plasma membrane of astrocytes and coupled to the MAP/Src-kinase pathway
    • Pawlak J., Karolczak M., Krust A., Chambon P., Beyer C. Estrogen receptor-alpha is associated with the plasma membrane of astrocytes and coupled to the MAP/Src-kinase pathway. Glia 2005, 50:270-275.
    • (2005) Glia , vol.50 , pp. 270-275
    • Pawlak, J.1    Karolczak, M.2    Krust, A.3    Chambon, P.4    Beyer, C.5
  • 72
    • 0030848432 scopus 로고    scopus 로고
    • Estrogens attenuate neuronal injury due to hemoglobin, chemical hypoxia, and excitatory amino acids in murine cortical cultures
    • Regan R.F., Guo Y. Estrogens attenuate neuronal injury due to hemoglobin, chemical hypoxia, and excitatory amino acids in murine cortical cultures. Brain Res. 1997, 764:133-140.
    • (1997) Brain Res. , vol.764 , pp. 133-140
    • Regan, R.F.1    Guo, Y.2
  • 73
    • 0024406708 scopus 로고
    • Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex
    • Rosenberg P.A., Aizenman E. Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex. Neurosci. Lett. 1989, 103:162-168.
    • (1989) Neurosci. Lett. , vol.103 , pp. 162-168
    • Rosenberg, P.A.1    Aizenman, E.2
  • 74
    • 0029030610 scopus 로고
    • Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis
    • Rothstein J.D., Van Kammen M., Levey A.I., Martin L.J., Kuncl R.W. Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis. Ann. Neurol. 1995, 38:73-84.
    • (1995) Ann. Neurol. , vol.38 , pp. 73-84
    • Rothstein, J.D.1    Van Kammen, M.2    Levey, A.I.3    Martin, L.J.4    Kuncl, R.W.5
  • 75
    • 52049094598 scopus 로고    scopus 로고
    • Interleukin-1beta-dependent signaling between astrocytes and neurons depends critically on astrocytic calcineurin/NFAT activity
    • Sama M.A., Mathis D.M., Furman J.L., Abdul H.M., Artiushin I.A., Kraner S.D., Norris C.M. Interleukin-1beta-dependent signaling between astrocytes and neurons depends critically on astrocytic calcineurin/NFAT activity. J. Biol. Chem. 2008, 283:21953-21964.
    • (2008) J. Biol. Chem. , vol.283 , pp. 21953-21964
    • Sama, M.A.1    Mathis, D.M.2    Furman, J.L.3    Abdul, H.M.4    Artiushin, I.A.5    Kraner, S.D.6    Norris, C.M.7
  • 78
    • 0034727094 scopus 로고    scopus 로고
    • Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase
    • Simoncini T., Hafezi-Moghadam A., Brazil D.P., Ley K., Chin W.W., Liao J.K. Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase. Nature 2000, 407:538-541.
    • (2000) Nature , vol.407 , pp. 538-541
    • Simoncini, T.1    Hafezi-Moghadam, A.2    Brazil, D.P.3    Ley, K.4    Chin, W.W.5    Liao, J.K.6
  • 80
  • 81
    • 0033118665 scopus 로고    scopus 로고
    • The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons
    • Singer C.A., Figueroa-Masot X.A., Batchelor R.H., Dorsa D.M. The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons. J. Neurosci. 1999, 19:2455-2463.
    • (1999) J. Neurosci. , vol.19 , pp. 2455-2463
    • Singer, C.A.1    Figueroa-Masot, X.A.2    Batchelor, R.H.3    Dorsa, D.M.4
  • 82
    • 14844316278 scopus 로고    scopus 로고
    • Positive and negative regulation of EAAT2 by NF-kappaB: a role for N-myc in TNFalpha-controlled repression
    • Sitcheran R., Gupta P., Fisher P.B., Baldwin A.S. Positive and negative regulation of EAAT2 by NF-kappaB: a role for N-myc in TNFalpha-controlled repression. Embo J. 2005, 24:510-520.
    • (2005) Embo J. , vol.24 , pp. 510-520
    • Sitcheran, R.1    Gupta, P.2    Fisher, P.B.3    Baldwin, A.S.4
  • 83
    • 33750965014 scopus 로고    scopus 로고
    • Estrogen-BDNF interactions: implications for neurodegenerative diseases
    • Sohrabji F., Lewis D.K. Estrogen-BDNF interactions: implications for neurodegenerative diseases. Front. Neuroendocrinol. 2006, 27:404-414.
    • (2006) Front. Neuroendocrinol. , vol.27 , pp. 404-414
    • Sohrabji, F.1    Lewis, D.K.2
  • 87
    • 84879315379 scopus 로고    scopus 로고
    • Estrogen mediates neuroprotection and anti-inflammatory effects during EAE through ERalpha signaling on astrocytes but not through ERbeta signaling on astrocytes or neurons
    • Spence R.D., Wisdom A.J., Cao Y., Hill H.M., Mongerson C.R., Stapornkul B., Itoh N., Sofroniew M.V., Voskuhl R.R. Estrogen mediates neuroprotection and anti-inflammatory effects during EAE through ERalpha signaling on astrocytes but not through ERbeta signaling on astrocytes or neurons. J. Neurosci. 2013, 33:10924-10933.
    • (2013) J. Neurosci. , vol.33 , pp. 10924-10933
    • Spence, R.D.1    Wisdom, A.J.2    Cao, Y.3    Hill, H.M.4    Mongerson, C.R.5    Stapornkul, B.6    Itoh, N.7    Sofroniew, M.V.8    Voskuhl, R.R.9
  • 88
    • 0037452698 scopus 로고    scopus 로고
    • Insights into glutamate transport regulation in human astrocytes: cloning of the promoter for excitatory amino acid transporter 2 (EAAT2)
    • Su Z.Z., Leszczyniecka M., Kang D.C., Sarkar D., Chao W., Volsky D.J., Fisher P.B. Insights into glutamate transport regulation in human astrocytes: cloning of the promoter for excitatory amino acid transporter 2 (EAAT2). Proc. Natl. Acad. Sci. USA 2003, 100:1955-1960.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 1955-1960
    • Su, Z.Z.1    Leszczyniecka, M.2    Kang, D.C.3    Sarkar, D.4    Chao, W.5    Volsky, D.J.6    Fisher, P.B.7
  • 90
    • 0037007635 scopus 로고    scopus 로고
    • The amazing astrocyte
    • Svendsen C.N. The amazing astrocyte. Nature 2002, 417:29-32.
    • (2002) Nature , vol.417 , pp. 29-32
    • Svendsen, C.N.1
  • 92
    • 0033016186 scopus 로고    scopus 로고
    • Estrogen hormones reduce lipid peroxidation in cells and tissues of the central nervous system
    • Vedder H., Anthes N., Stumm G., Wurz C., Behl C., Krieg J.C. Estrogen hormones reduce lipid peroxidation in cells and tissues of the central nervous system. J. Neurochem. 1999, 72:2531-2538.
    • (1999) J. Neurochem. , vol.72 , pp. 2531-2538
    • Vedder, H.1    Anthes, N.2    Stumm, G.3    Wurz, C.4    Behl, C.5    Krieg, J.C.6
  • 93
    • 51749112880 scopus 로고    scopus 로고
    • Estrogen anti-inflammatory activity in brain: a therapeutic opportunity for menopause and neurodegenerative diseases
    • Vegeto E., Benedusi V., Maggi A. Estrogen anti-inflammatory activity in brain: a therapeutic opportunity for menopause and neurodegenerative diseases. Front. Neuroendocrinol. 2008, 29:507-519.
    • (2008) Front. Neuroendocrinol. , vol.29 , pp. 507-519
    • Vegeto, E.1    Benedusi, V.2    Maggi, A.3
  • 94
    • 0035956960 scopus 로고    scopus 로고
    • Morphological abnormalities in the brains of estrogen receptor beta knockout mice
    • Wang L., Andersson S., Warner M., Gustafsson J.A. Morphological abnormalities in the brains of estrogen receptor beta knockout mice. Proc. Natl. Acad. Sci. USA 2001, 98:2792-2796.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 2792-2796
    • Wang, L.1    Andersson, S.2    Warner, M.3    Gustafsson, J.A.4
  • 95
    • 80054773465 scopus 로고    scopus 로고
    • Transforming growth factor alpha transforms astrocytes to a growth-supportive phenotype after spinal cord injury
    • White R.E., Rao M., Gensel J.C., McTigue D.M., Kaspar B.K., Jakeman L.B. Transforming growth factor alpha transforms astrocytes to a growth-supportive phenotype after spinal cord injury. J. Neurosci. 2011, 31:15173-15187.
    • (2011) J. Neurosci. , vol.31 , pp. 15173-15187
    • White, R.E.1    Rao, M.2    Gensel, J.C.3    McTigue, D.M.4    Kaspar, B.K.5    Jakeman, L.B.6
  • 96
    • 0036674986 scopus 로고    scopus 로고
    • Estrogens and neuroprotection
    • Wise P.M. Estrogens and neuroprotection. Trends Endocrinol. Metab. 2002, 13:229-230.
    • (2002) Trends Endocrinol. Metab. , vol.13 , pp. 229-230
    • Wise, P.M.1
  • 97
    • 84880202236 scopus 로고    scopus 로고
    • Flavonoids induce the synthesis and secretion of neurotrophic factors in cultured rat astrocytes: a signaling response mediated by estrogen receptor
    • Xu S.L., Bi C.W., Choi R.C., Zhu K.Y., Miernisha A., Dong T.T., Tsim K.W. Flavonoids induce the synthesis and secretion of neurotrophic factors in cultured rat astrocytes: a signaling response mediated by estrogen receptor. Evid. Based Complement. Alternat. Med. 2013, 2013:127075.
    • (2013) Evid. Based Complement. Alternat. Med. , vol.2013 , pp. 127075
    • Xu, S.L.1    Bi, C.W.2    Choi, R.C.3    Zhu, K.Y.4    Miernisha, A.5    Dong, T.T.6    Tsim, K.W.7
  • 98
    • 0031415298 scopus 로고    scopus 로고
    • Post-occlusion treatment with BDNF reduces infarct size in a model of permanent occlusion of the middle cerebral artery in rat
    • Yamashita K., Wiessner C., Lindholm D., Thoenen H., Hossmann K.A. Post-occlusion treatment with BDNF reduces infarct size in a model of permanent occlusion of the middle cerebral artery in rat. Metab. Brain Dis. 1997, 12:271-280.
    • (1997) Metab. Brain Dis. , vol.12 , pp. 271-280
    • Yamashita, K.1    Wiessner, C.2    Lindholm, D.3    Thoenen, H.4    Hossmann, K.A.5
  • 99
    • 77956285989 scopus 로고    scopus 로고
    • Extranuclear estrogen receptors mediate the neuroprotective effects of estrogen in the rat hippocampus
    • Yang L.C., Zhang Q.G., Zhou C.F., Yang F., Zhang Y.D., Wang R.M., Brann D.W. Extranuclear estrogen receptors mediate the neuroprotective effects of estrogen in the rat hippocampus. PLoS ONE 2010, 5:e9851.
    • (2010) PLoS ONE , vol.5
    • Yang, L.C.1    Zhang, Q.G.2    Zhou, C.F.3    Yang, F.4    Zhang, Y.D.5    Wang, R.M.6    Brann, D.W.7
  • 100
    • 77957021581 scopus 로고    scopus 로고
    • Astrocyte heterogeneity: an underappreciated topic in neurobiology
    • Zhang Y., Barres B.A. Astrocyte heterogeneity: an underappreciated topic in neurobiology. Curr. Opin. Neurobiol. 2010, 20:588-594.
    • (2010) Curr. Opin. Neurobiol. , vol.20 , pp. 588-594
    • Zhang, Y.1    Barres, B.A.2
  • 101
    • 80052293585 scopus 로고    scopus 로고
    • C terminus of Hsc70-interacting protein (CHIP)-mediated degradation of hippocampal estrogen receptor-alpha and the critical period hypothesis of estrogen neuroprotection
    • Zhang Q.G., Han D., Wang R.M., Dong Y., Yang F., Vadlamudi R.K., Brann D.W. C terminus of Hsc70-interacting protein (CHIP)-mediated degradation of hippocampal estrogen receptor-alpha and the critical period hypothesis of estrogen neuroprotection. Proc. Natl. Acad. Sci. USA 2011, 108:E617-E624.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108
    • Zhang, Q.G.1    Han, D.2    Wang, R.M.3    Dong, Y.4    Yang, F.5    Vadlamudi, R.K.6    Brann, D.W.7
  • 102
    • 34548681666 scopus 로고    scopus 로고
    • Estrogen receptor alpha and beta differentially regulate intracellular Ca(2+) dynamics leading to ERK phosphorylation and estrogen neuroprotection in hippocampal neurons
    • Zhao L., Brinton R.D. Estrogen receptor alpha and beta differentially regulate intracellular Ca(2+) dynamics leading to ERK phosphorylation and estrogen neuroprotection in hippocampal neurons. Brain Res. 2007, 1172:48-59.
    • (2007) Brain Res. , vol.1172 , pp. 48-59
    • Zhao, L.1    Brinton, R.D.2
  • 103
    • 2342630011 scopus 로고    scopus 로고
    • Estrogen receptor subtypes alpha and beta contribute to neuroprotection and increased Bcl-2 expression in primary hippocampal neurons
    • Zhao L., Wu T.W., Brinton R.D. Estrogen receptor subtypes alpha and beta contribute to neuroprotection and increased Bcl-2 expression in primary hippocampal neurons. Brain Res. 2004, 1010:22-34.
    • (2004) Brain Res. , vol.1010 , pp. 22-34
    • Zhao, L.1    Wu, T.W.2    Brinton, R.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.