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Volumn 56, Issue 5, 1999, Pages 471-481

Estrogen and NGF synergistically protect terminally differentiated, ERα-transfected PC12 cells from apoptosis

Author keywords

Apoptosis; BAD; Bcl 2; Bcl X; Cell death; Estrogen estradiol; Steroid receptors

Indexed keywords

ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; MESSENGER RNA; NERVE GROWTH FACTOR; PROTEIN BCL 2; PROTEIN BCL X; STEROID RECEPTOR;

EID: 0033152867     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19990601)56:5<471::AID-JNR3>3.0.CO;2-1     Document Type: Article
Times cited : (78)

References (53)
  • 1
    • 0026046948 scopus 로고
    • Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: Correlation with suppression of endonuclease activity
    • Batistatou A, Greene LA. 1991. Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: correlation with suppression of endonuclease activity. J Cell Biol 115:461-471.
    • (1991) J Cell Biol , vol.115 , pp. 461-471
    • Batistatou, A.1    Greene, L.A.2
  • 2
    • 0027427493 scopus 로고
    • Bcl-2 affects survival but not neuronal differentiation of PC12 cells
    • Batistatou A, Merry DE, Korsmeyer SJ, Greene LA. 1993. Bcl-2 affects survival but not neuronal differentiation of PC12 cells. J Neurosci 13:4422-4428.
    • (1993) J Neurosci , vol.13 , pp. 4422-4428
    • Batistatou, A.1    Merry, D.E.2    Korsmeyer, S.J.3    Greene, L.A.4
  • 3
    • 0028971169 scopus 로고
    • 17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro
    • Behl C, Widmann M, Trapp T, Holsboer F. 1995. 17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro. Biochem Biophys Res Commun 216:473-482.
    • (1995) Biochem Biophys Res Commun , vol.216 , pp. 473-482
    • Behl, C.1    Widmann, M.2    Trapp, T.3    Holsboer, F.4
  • 4
    • 0027968210 scopus 로고
    • Estradiol treatment increases viability of glioma and neuroblastoma cells in vitro
    • Bishop J, Simpkins JW. 1994. Estradiol treatment increases viability of glioma and neuroblastoma cells in vitro. Mol Cell Neurosci 5:303-308.
    • (1994) Mol Cell Neurosci , vol.5 , pp. 303-308
    • Bishop, J.1    Simpkins, J.W.2
  • 5
    • 0027465170 scopus 로고
    • Estrogen receptor immunoreactivity in rat brain: Rapid effects of estradiol injection
    • Blaustein JD. 1993. Estrogen receptor immunoreactivity in rat brain: rapid effects of estradiol injection. Endocrinology 132:1218-1224.
    • (1993) Endocrinology , vol.132 , pp. 1218-1224
    • Blaustein, J.D.1
  • 7
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomcyznski P, Sacchi N. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomcyznski, P.1    Sacchi, N.2
  • 9
    • 0029103293 scopus 로고
    • Future therapeutic developments of estrogen use
    • Fillit H. 1995. Future therapeutic developments of estrogen use. J Clin Pharm 35:25S-28S.
    • (1995) J Clin Pharm , vol.35
    • Fillit, H.1
  • 11
    • 0028324310 scopus 로고
    • Analysis of cell cycle-related gene expression in postmitotic neurons: Selective induction of cyclin D1 during programmed cell death
    • Freeman RS, Estus S, Johnson EMJ. 1994. Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of cyclin D1 during programmed cell death. Neuron 12:343-355.
    • (1994) Neuron , vol.12 , pp. 343-355
    • Freeman, R.S.1    Estus, S.2    Johnson, E.M.J.3
  • 13
    • 0030975797 scopus 로고    scopus 로고
    • Identification of estrogen responsive genes in neuroblastoma SK-ER3 cells
    • Garnier M, Di Lorenzo D, Albertini A, Maggi A. 1997. Identification of estrogen responsive genes in neuroblastoma SK-ER3 cells. J Neurosci 17:4591-4599.
    • (1997) J Neurosci , vol.17 , pp. 4591-4599
    • Garnier, M.1    Di Lorenzo, D.2    Albertini, A.3    Maggi, A.4
  • 14
    • 0026693260 scopus 로고
    • Effects of estrogen and fimbria/fornix transection on p75NGFR and ChAT expression in the medial septum and diagonal band of Broca
    • Gibbs R, Pfaff DW. 1992. Effects of estrogen and fimbria/fornix transection on p75NGFR and ChAT expression in the medial septum and diagonal band of Broca. Exp Neurol 116:23-39.
    • (1992) Exp Neurol , vol.116 , pp. 23-39
    • Gibbs, R.1    Pfaff, D.W.2
  • 15
    • 0030580456 scopus 로고    scopus 로고
    • Expression pattern of candidate cell death effector proteins Bax, Bcl2, Bcl-X and c-jun in sensory and motor neurons following sciatic nerve transection in the rat
    • Gillardon F, Klimaschewski L, Wickert H, Krajewski S, Reed JC, Zimmermann M. 1996. Expression pattern of candidate cell death effector proteins Bax, Bcl2, Bcl-X and c-jun in sensory and motor neurons following sciatic nerve transection in the rat. Brain Res 739:244-250.
    • (1996) Brain Res , vol.739 , pp. 244-250
    • Gillardon, F.1    Klimaschewski, L.2    Wickert, H.3    Krajewski, S.4    Reed, J.C.5    Zimmermann, M.6
  • 16
    • 0030747261 scopus 로고    scopus 로고
    • Different mechanisms for inhibition of cell proliferation via cell cycle proteins in PC12 cells by nerve growth factor and staurosporine
    • Gollapudi L, Neet KN. 1997. Different mechanisms for inhibition of cell proliferation via cell cycle proteins in PC12 cells by nerve growth factor and staurosporine. J Neurosci Res 49:461-474.
    • (1997) J Neurosci Res , vol.49 , pp. 461-474
    • Gollapudi, L.1    Neet, K.N.2
  • 17
    • 0344678396 scopus 로고    scopus 로고
    • Increased expression of estrogen receptor in PC12 cells: Effects on neurite outgrowth
    • Gollapudi L, Oblinger MM. 1997. Increased expression of estrogen receptor in PC12 cells: Effects on neurite outgrowth. Soc Neurosci Abstr 23:343.
    • (1997) Soc Neurosci Abstr , vol.23 , pp. 343
    • Gollapudi, L.1    Oblinger, M.M.2
  • 18
    • 0033118387 scopus 로고    scopus 로고
    • Stable transfection of PC12 cells with estrogen receptor (ERα): Protective effects of estrogen on cell survival after serum deprivation
    • Gollapudi L, Oblinger MM. 1999. Stable transfection of PC12 cells with estrogen receptor (ERα): protective effects of estrogen on cell survival after serum deprivation. J Neurosci Res 56:99-108.
    • (1999) J Neurosci Res , vol.56 , pp. 99-108
    • Gollapudi, L.1    Oblinger, M.M.2
  • 19
    • 0029073131 scopus 로고
    • Bcl-X is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death
    • Gonzalez-Garcia M, Garcia I, Ding L, O'Shea S, Boise LH. 1995. Bcl-X is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death. PNAS 92:4304-4308.
    • (1995) PNAS , vol.92 , pp. 4304-4308
    • Gonzalez-Garcia, M.1    Garcia, I.2    Ding, L.3    O'Shea, S.4    Boise, L.H.5
  • 20
    • 0031940591 scopus 로고    scopus 로고
    • Nuclear estrogen receptor-independent neuroprotection by estratrienes : A novel interaction with glutathione
    • Green PS, Gridley KE, Simpkins JW. 1998. Nuclear estrogen receptor-independent neuroprotection by estratrienes : a novel interaction with glutathione. Neuroscience 84:7-10.
    • (1998) Neuroscience , vol.84 , pp. 7-10
    • Green, P.S.1    Gridley, K.E.2    Simpkins, J.W.3
  • 22
    • 0018085012 scopus 로고
    • Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium
    • Greene LA. 1978. Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium. J Cell Biol 78:747-755.
    • (1978) J Cell Biol , vol.78 , pp. 747-755
    • Greene, L.A.1
  • 23
    • 0345704610 scopus 로고
    • Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
    • Greene LA, Tischler AS. 1976. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. PNAS 73:2424-2428.
    • (1976) PNAS , vol.73 , pp. 2424-2428
    • Greene, L.A.1    Tischler, A.S.2
  • 24
    • 0029091740 scopus 로고
    • Role of Bcl-2 in the survival and function of developing and mature sympathetic neurons
    • Greenlund LJS, Korsmeyer SJ, Johnson EMJ. 1995. Role of Bcl-2 in the survival and function of developing and mature sympathetic neurons. Neuron 15:649-661.
    • (1995) Neuron , vol.15 , pp. 649-661
    • Greenlund, L.J.S.1    Korsmeyer, S.J.2    Johnson, E.M.J.3
  • 25
    • 0029868112 scopus 로고    scopus 로고
    • The E1b 19K protein blocks apoptosis by interacting with and inhibiting the p53 inducible and death promoting Bax protein
    • Han J, Sabbatini P, Ferez D, Rao L, Modha D, White E. 1996. The E1b 19K protein blocks apoptosis by interacting with and inhibiting the p53 inducible and death promoting Bax protein. Genes Dev 10:461-477.
    • (1996) Genes Dev , vol.10 , pp. 461-477
    • Han, J.1    Sabbatini, P.2    Ferez, D.3    Rao, L.4    Modha, D.5    White, E.6
  • 26
    • 0026514846 scopus 로고
    • Expression of estrogen receptor in the rat brain : Detection of its mRNA using reverse transcription-polymerase chain reaction
    • Hirata S, Osada T, Hirai M, Hagihara K, Kato J. 1992. Expression of estrogen receptor in the rat brain : detection of its mRNA using reverse transcription-polymerase chain reaction. J Steroid Biochem Mol Biol 4:583-587.
    • (1992) J Steroid Biochem Mol Biol , vol.4 , pp. 583-587
    • Hirata, S.1    Osada, T.2    Hirai, M.3    Hagihara, K.4    Kato, J.5
  • 27
    • 0026581722 scopus 로고
    • Estrogen as a growth factor to central nervous cells. Estrogen promotes development of acetylcholinesterase positive basal forebrain neurons transplanted in the anterior eye chamber
    • Honjo H, Tamura T, Matsumoto Y, Kawata M, Ogino Y, Tanaka K, Yamamoto T, Veda S, Okada H. 1992. Estrogen as a growth factor to central nervous cells. Estrogen promotes development of acetylcholinesterase positive basal forebrain neurons transplanted in the anterior eye chamber. J Steroid Biochem Mol Biol 41:633-635.
    • (1992) J Steroid Biochem Mol Biol , vol.41 , pp. 633-635
    • Honjo, H.1    Tamura, T.2    Matsumoto, Y.3    Kawata, M.4    Ogino, Y.5    Tanaka, K.6    Yamamoto, T.7    Veda, S.8    Okada, H.9
  • 28
    • 2142721829 scopus 로고    scopus 로고
    • Interference of BAD (Bcl-XL/Bcl-2-associated death promoter)-induced apoptosis in mammalian cells by 14-3-3 isoforms and P11
    • Hsu SY, Kaipia A, Zhu L, Hsueh JW. 1997. Interference of BAD (Bcl-XL/Bcl-2-associated death promoter)-induced apoptosis in mammalian cells by 14-3-3 isoforms and P11. Mol Endocrinol 11:1858-1867.
    • (1997) Mol Endocrinol , vol.11 , pp. 1858-1867
    • Hsu, S.Y.1    Kaipia, A.2    Zhu, L.3    Hsueh, J.W.4
  • 29
    • 0031018983 scopus 로고    scopus 로고
    • Estrogen increases intracellular p26Bcl-2 to p21Bax ratios and inhibits taxol-induced apoptosis of human breast cancer MCF-7 cells
    • Huang Y, Ray S, Reed JC, Ibrado AM, Nawabi A, Bhalla K. 1997. Estrogen increases intracellular p26Bcl-2 to p21Bax ratios and inhibits taxol-induced apoptosis of human breast cancer MCF-7 cells. Breast Cancer Res Treatise 42:73-81.
    • (1997) Breast Cancer Res Treatise , vol.42 , pp. 73-81
    • Huang, Y.1    Ray, S.2    Reed, J.C.3    Ibrado, A.M.4    Nawabi, A.5    Bhalla, K.6
  • 30
    • 0028558891 scopus 로고
    • Steroid hormone effects on gene expression, neuronal structure, and differentiation
    • Kawata M, Yuri K, Morimoto M. 1994. Steroid hormone effects on gene expression, neuronal structure, and differentiation. Hormones Behav 28:477-482.
    • (1994) Hormones Behav , vol.28 , pp. 477-482
    • Kawata, M.1    Yuri, K.2    Morimoto, M.3
  • 32
    • 0028225403 scopus 로고
    • An in vitro model for the effects of estrogen on neurons employing estrogen receptor-transfected PC12 cells
    • Lustig RH, Hua P, Yu W, Ahmad FJ, Baas PW. 1994. An in vitro model for the effects of estrogen on neurons employing estrogen receptor-transfected PC12 cells. J Neurosci 14:3945-3957.
    • (1994) J Neurosci , vol.14 , pp. 3945-3957
    • Lustig, R.H.1    Hua, P.2    Yu, W.3    Ahmad, F.J.4    Baas, P.W.5
  • 33
    • 0030872142 scopus 로고    scopus 로고
    • BCL-2 related protein expression in apoptosis: Oxidative stress versus serum deprivation in PC12 cells
    • Maroto R, Perez-Polo RJ. 1997. BCL-2 related protein expression in apoptosis: oxidative stress versus serum deprivation in PC12 cells. J Neurochem 69:514-523.
    • (1997) J Neurochem , vol.69 , pp. 514-523
    • Maroto, R.1    Perez-Polo, R.J.2
  • 34
    • 0031057656 scopus 로고    scopus 로고
    • Bcl-2 gene family in the nervous system
    • Merry DE, Korsmeyer SJ. 1997. Bcl-2 gene family in the nervous system. Ann Rev Neurosci 20:245-267.
    • (1997) Ann Rev Neurosci , vol.20 , pp. 245-267
    • Merry, D.E.1    Korsmeyer, S.J.2
  • 35
    • 0028839253 scopus 로고
    • A timetable of events during programmed cell death induced by trophic factor withdrawal from neuronal PC12 cells
    • Mesner PW, Epting CL, Hegarty JL, Green SH. 1995. A timetable of events during programmed cell death induced by trophic factor withdrawal from neuronal PC12 cells. J Neurosci 15:7357-7366.
    • (1995) J Neurosci , vol.15 , pp. 7357-7366
    • Mesner, P.W.1    Epting, C.L.2    Hegarty, J.L.3    Green, S.H.4
  • 36
    • 0027071804 scopus 로고
    • Nerve growth factor withdrawal-induced cell death in neuronal PC12 cells resembles that in sympathetic neurons
    • Mesner PW, Winters TR, Green SH. 1992. Nerve growth factor withdrawal-induced cell death in neuronal PC12 cells resembles that in sympathetic neurons. J Cell Biol 119:1669-1680.
    • (1992) J Cell Biol , vol.119 , pp. 1669-1680
    • Mesner, P.W.1    Winters, T.R.2    Green, S.H.3
  • 37
    • 0027507967 scopus 로고
    • Presumptive estrogen target neurons express mRNAs for the neurotrophins and neurotrophin receptors: A basis for potential developmental interactions of estrogen with the neurotrophins
    • Miranda RC, Sohrabji F, Toran-Allerand CD. 1993. Presumptive estrogen target neurons express mRNAs for the neurotrophins and neurotrophin receptors: a basis for potential developmental interactions of estrogen with the neurotrophins. Mol Cell Neurosci 4:510-525.
    • (1993) Mol Cell Neurosci , vol.4 , pp. 510-525
    • Miranda, R.C.1    Sohrabji, F.2    Toran-Allerand, C.D.3
  • 38
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltavi ZN, Millman CL, Korsmeyer SJ. 1993. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74:609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltavi, Z.N.1    Millman, C.L.2    Korsmeyer, S.J.3
  • 39
    • 0024465402 scopus 로고
    • Cell cycle-specific action of nerve growth factor in PC12 cells: Differentiation without proliferation
    • Rudkin BB, Lazarovici P, Levi B, Abe Y, Fujita K, Guroff G. 1989. Cell cycle-specific action of nerve growth factor in PC12 cells: Differentiation without proliferation. EMBO J 8:3319-3325.
    • (1989) EMBO J , vol.8 , pp. 3319-3325
    • Rudkin, B.B.1    Lazarovici, P.2    Levi, B.3    Abe, Y.4    Fujita, K.5    Guroff, G.6
  • 40
    • 0025939423 scopus 로고
    • Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms
    • Rukenstein A, Rydel RE, Greene LA. 1991. Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms. J Neurosci 11:2552-2563.
    • (1991) J Neurosci , vol.11 , pp. 2552-2563
    • Rukenstein, A.1    Rydel, R.E.2    Greene, L.A.3
  • 42
    • 0027984086 scopus 로고
    • The potential role for estrogen replacement therapy in the treatment of the cognitive decline and neurodegeneration associated with Alzheimer's disease
    • Simkins JW, Singh M, Bishop J. 1994. The potential role for estrogen replacement therapy in the treatment of the cognitive decline and neurodegeneration associated with Alzheimer's disease. Neurobiol Aging 15:S195-S197.
    • (1994) Neurobiol Aging , vol.15
    • Simkins, J.W.1    Singh, M.2    Bishop, J.3
  • 43
    • 0030818062 scopus 로고    scopus 로고
    • Role of estrogen replacement therapy in memory enhancement and the prevention of neuronal loss associated with Alzheimer's disease
    • Simpkins JW, Green PS, Gridley KE, Singh M, deFiebre NC, Rajakumar G. 1997. Role of estrogen replacement therapy in memory enhancement and the prevention of neuronal loss associated with Alzheimer's disease. Am J Med 103:19S-25S.
    • (1997) Am J Med , vol.103
    • Simpkins, J.W.1    Green, P.S.2    Gridley, K.E.3    Singh, M.4    DeFiebre, N.C.5    Rajakumar, G.6
  • 44
  • 45
    • 0028238769 scopus 로고
    • Functions of the neurotrophins during nervous system development: What the knockouts are teaching us
    • Snider WD. 1994. Functions of the neurotrophins during nervous system development: what the knockouts are teaching us. Cell 77:627-638.
    • (1994) Cell , vol.77 , pp. 627-638
    • Snider, W.D.1
  • 46
    • 0028264440 scopus 로고
    • Reciprocal regulation of estrogen and NGF receptors by their ligands in PC12 cells
    • Sohrabji F, Greene LA, Miranda RC, Toran-Allerand CD. 1994. Reciprocal regulation of estrogen and NGF receptors by their ligands in PC12 cells. J Neurobiol 25:974-988.
    • (1994) J Neurobiol , vol.25 , pp. 974-988
    • Sohrabji, F.1    Greene, L.A.2    Miranda, R.C.3    Toran-Allerand, C.D.4
  • 47
    • 0030665659 scopus 로고    scopus 로고
    • The role of the Bcl-2 ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy
    • Strasser A, Huang DCS, Vaux DL. 1997. The role of the Bcl-2 ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy. Biochem Biophys Acta 1333:F151-F178.
    • (1997) Biochem Biophys Acta , vol.1333
    • Strasser, A.1    Huang, D.C.S.2    Vaux, D.L.3
  • 49
    • 0028891851 scopus 로고
    • Expression of members of the Bcl-2 gene family in the immature rat ovary: Equine chorionic gonadotropin mediated inhibition of granulosa cell apoptosis is associated with decreased bax and constitutive Bcl-2 and Bcl-xl messenger ribonucleic acid levels
    • Tilly JL, Tilly KI, Kenton ML, Johnson AL. 1995. Expression of members of the Bcl-2 gene family in the immature rat ovary: equine chorionic gonadotropin mediated inhibition of granulosa cell apoptosis is associated with decreased Bax and constitutive Bcl-2 and Bcl-xl messenger ribonucleic acid levels. Endocrinology 136:232-292.
    • (1995) Endocrinology , vol.136 , pp. 232-292
    • Tilly, J.L.1    Tilly, K.I.2    Kenton, M.L.3    Johnson, A.L.4
  • 50
    • 0017229245 scopus 로고
    • Sex steroids and the development of the newborn mouse hypothalamus and preoptic area in vitro: Implications for sexual differentiation
    • Toran-Allerand DC. 1976. Sex steroids and the development of the newborn mouse hypothalamus and preoptic area in vitro: implications for sexual differentiation. Brain Res 106:407-412.
    • (1976) Brain Res , vol.106 , pp. 407-412
    • Toran-Allerand, D.C.1
  • 52
    • 0028809209 scopus 로고
    • Bad, a heterodimeric partner for Bcl-Xl and Bcl-2, displaces Bax and promotes cell death
    • Yang E, Zha J, Jockei J, Boise LH, Thompson CB, Korsemeyer SJ. 1995. Bad, a heterodimeric partner for Bcl-Xl and Bcl-2, displaces Bax and promotes cell death. Cell 80:285-291.
    • (1995) Cell , vol.80 , pp. 285-291
    • Yang, E.1    Zha, J.2    Jockei, J.3    Boise, L.H.4    Thompson, C.B.5    Korsemeyer, S.J.6
  • 53
    • 0030980751 scopus 로고    scopus 로고
    • Neonatal diethylstilbestrol treatment alters the estrogen-regulated expression of both cell proliferation and apoptosis -related protooncogenes (c-jun, c-myc, bax, bcl-2, and bcl-x) in the hamster uterus
    • Zheng X, Hendry WJ. 1997. Neonatal diethylstilbestrol treatment alters the estrogen-regulated expression of both cell proliferation and apoptosis -related protooncogenes (c-jun, c-myc, bax, bcl-2, and bcl-x) in the hamster uterus. Cell Growth Differ 8:425-434.
    • (1997) Cell Growth Differ , vol.8 , pp. 425-434
    • Zheng, X.1    Hendry, W.J.2


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