Endogenous melatonin provides an effective circadian message to both the suprachiasmatic nuclei and the pars tuberalis of the rat

Journal of Pineal Research

Volumn 46, Issue 1, 2009, Pages 95-105

  Agez, Laurence ^a   Laurent, Virginie ^a   Guerrero, Hilda Y ^a   Pévet, Paul ^a   Masson Pévet, Mireille ^a   Gauer, François ^a  

^a Hopitaux Universitaires de Strasbourg   (France)

Author keywords

In situ hybridization; Pars tuberalis; Pinealectomy; rev erb ; ror ; Suprachiasmatic nuclei

Indexed keywords

MELATONIN; MELATONIN RECEPTOR; PER1 PROTEIN; PER2 PROTEIN; CIRCADIAN RHYTHM SIGNALING PROTEIN; NR1D1 PROTEIN, RAT; NUCLEAR RECEPTOR NR1D1; PER1 PROTEIN, RAT; PER2 PROTEIN, RAT;

ANIMAL EXPERIMENT; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; HYPOPHYSIS PARS TUBERALIS; IN SITU HYBRIDIZATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PINEALECTOMY; RAT; ADENOHYPOPHYSIS; ANALYSIS OF VARIANCE; ANIMAL; BLOOD; GENETICS; MALE; METABOLISM; PHYSIOLOGY; PINEAL BODY; REGRESSION ANALYSIS; STATISTICAL MODEL; SUPRACHIASMATIC NUCLEUS; SURGERY; WISTAR RAT;

ANALYSIS OF VARIANCE; ANIMALS; CIRCADIAN RHYTHM; IN SITU HYBRIDIZATION; LEAST-SQUARES ANALYSIS; LINEAR MODELS; MALE; MELATONIN; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP D, MEMBER 1; PERIOD CIRCADIAN PROTEINS; PINEAL GLAND; PITUITARY GLAND, ANTERIOR; RATS; RATS, WISTAR; SUPRACHIASMATIC NUCLEUS;

EID: 57149144548     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2008.00636.x     Document Type: Article

References (47)

1. Buijs RM, Kalsbeek A. Hypothalamic integration of central and peripheral clocks. Nat Rev Neurosci 2001 7 : 521 526.
2. Kalsbeek A, Buijs RM. Output pathways of the mammalian suprachiasmatic nucleus: coding circadian time by transmitter selection and specific targeting. Cell Tissue Res 2002 309 : 109 118.
3. Perreau-Lenz S, Pévet P, Buijs RM, Kalsbeek A. The biological clock : a bodyguard of temporal homeostasis. Chronobiology Int 2004 21 : 143 151.
4. Pevet P, Agez L, Bothorel B et al. Melatonin in the multi-oscillatory mammalian circadian world. Chronobiol Int 2006 23 : 39 51.
5. Reiter RJ. The melatonin rhythm: both a clock and a calendar. Experientia 1993 49 : 654 664.
6. Vanecek J, Pavlik A, Illnerova H. Hypothalamic melatonin receptor sites revealed by autoradiography. Brain Res 1987 435 : 359 362.
7. Vanecek J. Cellular mechanisms of melatonin action. Physiol Rev 1998 78 : 687 721.
8. VonGall C, Stehle JH, Weaver DR. Mammalian melatonin receptors: molecular biology and signal transduction. Cell Tissue Res 2002 309 : 151 162.
9. Johnston JD. Photoperiodic regulation of prolactin secretion: changes in intra-pituitary signalling and lactotroph heterogeneity. J Endocrinol 2004 180 : 351 356.
10. Malpaux B, Tricoire H, Mailliet F et al. Melatonin and seasonal reproduction: understanding the neuroendocrine mechanisms using the sheep as a model. Reprod Suppl 2002 59 : 167 179.
11. Poirel VJ, Masson-Pevet M, Pevet P et al. MT1 melatonin receptor mRNA expression exhibits a circadian variation in the rat suprachiasmatic nuclei. Brain Res 2002 946 : 64 71.
12. Dubocovich ML, Yun K, Al-Ghoul WM, Benloucif S, Masana MI. Selective MT2 melatonin receptor antagonists block melatonin-mediated phase advances of circadian rhythms. FASEB J 1998 12 : 1211 1220.
13. Dubocovich ML, Hudson RL, Sumaya IC, Masana MI, Manna E. Effect of MT1 melatonin receptor deletion on melatonin-mediated phase shift of circadian rhythms in the C57BL/6 mouse. J Pineal Res 2005 39 : 113 120.
14. Reppert SM, Weaver DR. Coordination of circadian timing in mammals. Nature 2002 418 : 935 941.
15. Maywood ES, O'Brien JA, Hastings MH. Expression of mCLOCK and other circadian clock-relevant proteins in the mouse suprachiasmatic nuclei. J Neuroendocrinol 2003 15 : 329 334.
16. Hirota T, Fukada Y. Resetting mechanism of central and peripheral circadian clocks in mammals. Zoolog Sci 2004 21 : 359 368.
17. Poirel VJ, Boggio V, Dardente H et al. Contrary to other non-photic cues, acute melatonin injection does not induce immediate changes of clock gene mRNA expression in the rat suprachiasmatic nuclei. Neuroscience 2003 120 : 745 755.
18. Preitner N, Damiola F, Lopez-Molina L et al. The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator. Cell 2002 110 : 251 260.
19. Sato TK, Panda S, Miraglia LJ et al. A functional genomics strategy reveals Rora as a component of the mammalian circadian clock. Neuron 2004 43 : 527 537.
20. Akashi M, Takumi T. The orphan nuclear receptor RORalpha regulates circadian transcription of the mammalian core-clock Bmal1. Nat Struct Mol Biol 2005 12 : 441 448.
21. Yin L, Wang J, Klein PS, Lazar MA. Nuclear receptor Rev-erbalpha is a critical lithium-sensitive component of the circadian clock. Science 2006 311 : 1002 1005.
22. Agez L, Laurent V, Pevet P et al. Melatonin affects nuclear orphan receptors mRNA in the rat suprachiasmatic nuclei. Neuroscience 2007 144 : 522 530.
23. Cassone VM. Effects of melatonin on vertebrate circadian systems. Trends Neurosci 1990 13 : 457 464.
24. Pevet P, Bothorel B, Slotten H et al. The chronobiotic properties of melatonin. Cell Tissue Res 2002 309 : 183 191.
25. Slotten HA, Pitrosky B, Pevet P. Influence of the mode of daily melatonin administration on entrainment of rat circadian rhythms. J Biol Rhythms 1999 14 : 347 353.
26. Mauviard F, Pevet P, Forlot P. 5'5-Methoxypsoralen enhances plasma melatonin concentrations in the male rat: non-noradrenergic-mediated stimulation and lack of effect in pinealectomized animals. J Pineal Res 1991 11 : 35 41.
27. Schuster C, Gauer F, Guerrero H et al. Photic regulation of mt1 melatonin receptors in the Siberian hamster pars tuberalis and suprachiasmatic nuclei: involvement of the circadian clock and intergeniculate leaflet. J Neuroendocrinol 2000 12 : 207 216.
28. Onishi H, Yamaguchi S, Yagita K et al. Rev-erbalpha gene expression in the mouse brain with special emphasis on its circadian profiles in the suprachiasmatic nucleus. J Neurosci Res 2002 68 : 551 557.
29. Sumi Y, Yagita K, Yamaguchi S et al. Rhythmic expression of ROR beta mRNA in the mice suprachiasmatic nucleus. Neurosci Lett 2002 320 : 13 16.
30. Matsui D, Takekida S, Okamura H. Molecular oscillation of per1 and per2 genes in the rodent brain: an in situ hybridization and molecular biological study. Kobe J Med Sci 2005 51 : 85 93.
31. VonGall C, Garabette ML, Kell CA et al. Rhythmic gene expression in pituitary depends on heterologous sensitization by the neurohormone melatonin. Nat Neurosci 2002 5 : 234 238.
32. VonGall C, Weaver DR, Moek J et al. Melatonin plays a crucial role in the regulation of rhythmic clock gene expression in the mouse pars tuberalis. Ann N Y Acad Sci 2005 1040 : 508 511.
33. Oishi K, Murai I, Sakamoto K et al. The pineal gland is not essential for circadian expression of rat period homologue (rper2) mRNA in the suprachiasmatic nucleus and peripheral tissues. Brain Res 2000 885 : 298 302.
34. Amir S, Harbour VL, Robinson B. Pinealectomy does not affect diurnal PER2 expression in the rat limbic forebrain. Neurosci Lett 2006 15 : 147 150.
35. Johnston JD, Tournier BB, Andersson H et al. Multiple effects of melatonin on rhythmic clock gene expression in the mammalian pars tuberalis. Endocrinology 2006 147 : 959 965.
36. Redman J, Armstrong S, Ng KT. Free-running activity rhythms in the rat: entrainment by melatonin. Science 1983 219 : 1089 1091.
37. Enright JT. Methodology. In : Handbook of Behavioural Neurobiology, Vol. 4. Aschoff J, ed. Plenum Press, New York, 1981 pp. 11 19.
38. Pévet P. Melatonin. Dialogues Clin Neurosci 2002 4 : 57 72.
39. Cardinali DP, Pévet P. Basic aspects of melatonin action. Sleep Med Rev 1998 2 : 175 190.
40. Lima FB, Machado UF, Bartol I et al. Pinealectomy causes glucose intolerance and decreases adipose cell responsiveness to insulin in rats. Am J Physiol 1998 275 : E934 E941.
41. Rusak B, Yu GD. Regulation of melatonin sensitivity and firing-rate rhythms of hamster suprachiasmatic neurons: pinealectomy effects. Brain Res 1993 602 : 200 204.
42. Messager S, Garabette ML, Hastings MH, Hazlerigg DG. Tissue-specific abolition of Per1 expression in the pars tuberalis by pinealectomy in the Syrian hamster. Neuroreport 2001 12 : 579 582.
43. Hazlerigg DG, Morgan PJ, Messager S. Decoding photoperiodic time and melatonin in mammals: what can we learn from the pars tuberalis? J Biol Rhythms 2001 16 : 326 335.
44. Jilg A, Moek J, Weaver DR et al. Rhythms in clock proteins in the mouse pars tuberalis depend on MT1 melatonin receptor signalling. Eur J Neurosci 2005 22 : 2845 2854.
45. Gauer F, Masson-Pevet M, Stehle J, Pevet P. Daily variations in melatonin receptor density of rat pars tuberalis and suprachiasmatic nuclei are distinctly regulated. Brain Res 1994 641 : 92 98.
46. Gauer F, Masson-Pevet M, Pevet P. Differential regulation of melatonin receptors by short- versus long-term pinealectomy in the rat suprachiasmatic nuclei and pars tuberalis. J Pineal Res 1994 16 : 73 76.
47. Dardente H, Poirel VJ, Klosen P et al. Per and neuropeptide expression in the rat suprachiasmatic nuclei: compartmentalization and differential cellular induction by light. Brain Res 2002 958 : 261 271.