Leukocyte protease binding to nucleic acids promotes nuclear localization and cleavage of nucleic acid binding proteins

Journal of Immunology

Volumn 192, Issue 11, 2014, Pages 5390-5397

  Thomas, Marshall P ^c   Whangbo, Jennifer ^a,b   McCrossan, Geoffrey ^c   Deutsch, Aaron J ^c   Martinod, Kimberly ^c   Walch, Michael ^c   Lieberman, Judy ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF FRIBOURG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN G; DEOXYRIBONUCLEASE; GRANZYME A; GRANZYME B; HUR PROTEIN; LEUKOCYTE ELASTASE; LEUKOCYTE ENZYME; NUCLEIC ACID BINDING PROTEIN; RIBONUCLEASE; RNA BINDING PROTEIN;

ARTICLE; BINDING AFFINITY; BONE MARROW CELL; CELL LYSATE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME BINDING; ENZYME SPECIFICITY; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKOCYTE ACTIVATION; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DNA BINDING; PROTEIN RNA BINDING; PROTEIN TARGETING;

ACTIVE TRANSPORT, CELL NUCLEUS; CELL NUCLEUS; DNA; DNA-BINDING PROTEINS; FEMALE; GRANZYMES; HEK293 CELLS; HUMANS; MALE; NEUTROPHILS; PROTEOLYSIS; RNA; RNA-BINDING PROTEINS;

EID: 84901257282     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1303296     Document Type: Article

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