The cytotoxic T lymphocyte protease granzyme A cleaves and inactivates poly(adenosine 5′-diphosphate-ribose) polymerase-1

Blood

Volumn 114, Issue 6, 2009, Pages 1205-1216

  Zhu, Pengcheng ^a   Martinvalet, Denis ^a   Chowdhury, Dipanjan ^a   Zhang, Dong ^a   Schlesinger, Ann ^a   Lieberman, Judy ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CASPASE; GRANZYME A; LYSINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; GRANZYME; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; CATALYSIS; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DNA BINDING; DNA DAMAGE; DNA REPAIR; GENE MUTATION; GENE OVEREXPRESSION; MOUSE; NECROSIS; NONHUMAN; PRIORITY JOURNAL; AMINO ACID SUBSTITUTION; CD8+ T LYMPHOCYTE; CELL STRAIN K 562; ENZYMOLOGY; GENE EXPRESSION; GENETICS; HELA CELL; HUMAN; IMMUNOLOGY; METABOLISM; MISSENSE MUTATION; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SUBSTITUTION; APOPTOSIS; CASPASES; CD8-POSITIVE T-LYMPHOCYTES; DNA DAMAGE; DNA REPAIR; GENE EXPRESSION; GRANZYMES; HELA CELLS; HUMANS; K562 CELLS; MUTATION, MISSENSE; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN STRUCTURE, TERTIARY;

EID: 69849085156     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-12-195768     Document Type: Article

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