Ras-induced epigenetic inactivation of the RRAD (Ras-related associated with diabetes) gene promotes glucose uptake in a human ovarian cancer model

Journal of Biological Chemistry

Volumn 289, Issue 20, 2014, Pages 14225-14238

  Wang, Yan ^a,b   Li, Guiling ^c   Mao, Fengbiao ^b,d   Li, Xianfeng ^e   Liu, Qi ^c   Chen, Lin ^d   Lv, Lu ^c   Wang, Xin ^c   Wu, Jinyu ^c   Dai, Wei ^a   Wang, Guan ^f   Zhao, Enfeng ^f   Tang, Kai Fu ^c   Sun, Zhong Sheng ^c,d  

^a INSTITUTE OF PSYCHOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c WENZHOU MEDICAL UNIVERSITY   (China)

^d INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^e CENTRAL SOUTH UNIVERSITY   (China)

^f CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; CELL CULTURE; GLUCOSE; HISTOLOGY; RESTORATION; TISSUE; TRANSCRIPTION;

DNA METHYLTRANSFERASES; EPITHELIAL CELLS; FARNESYLTRANSFERASE; GLUCOSE TRANSPORTERS; HYPERMETHYLATION; ONCOGENIC TRANSFORMATION; REDUCED REPRESENTATION BISULFITE SEQUENCING; TUMOR SUPPRESSOR GENES;

DISEASES;

5 AZA 2' DEOXYCYTIDINE; DNA; DNA METHYLTRANSFERASE; LACTIC ACID; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE METHYL ESTER; PROTEIN RRAD; RAS PROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; GLUCOSE; HRAS PROTEIN, HUMAN; PROTEIN P21; RRAD PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; CANCER CELL LINE; CARCINOGENESIS; CONTROLLED STUDY; DNA METHYLATION; DOWN REGULATION; ENZYME ACTIVITY; EPIGENETICS; GENE EXPRESSION; GENE SEQUENCE; GENE SILENCING; GENETIC ASSOCIATION; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MOUSE; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; PROMOTER REGION; RRAD GENE; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE; UPREGULATION; ANIMAL; BIOSYNTHESIS; CELL TRANSFORMATION; DEFICIENCY; EPITHELIUM CELL; FEMALE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; OVARY TUMOR; PATHOLOGY; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE;

ADULT; AGED; ANIMALS; BIOLOGICAL TRANSPORT; CARCINOGENESIS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; DNA METHYLATION; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GLUCOSE; HUMANS; LACTIC ACID; MICE; MIDDLE AGED; OVARIAN NEOPLASMS; PROTO-ONCOGENE PROTEINS P21(RAS); RAS PROTEINS;

EID: 84901024004     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.527671     Document Type: Article

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